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Sheffield Biomedical Research Centre Public Launch

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Page 1: Sheffield Biomedical Research Centresheffieldbrc.nihr.ac.uk/wp-content/uploads/2019/01/... · creativity: Introducing The KAWA (river of life) Model In this model the river is your

Sheffield Biomedical

Research Centre

Public Launch

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This event aims to introduce the NIHR Sheffield Biomedical

Research Centre’s Translational Neuroscience research.

We would like to take the opportunity to thank patients and

the public who give their time to get involved with research.

We hope to present a chance to find out more about what

we do, meet like-minded others, and give more

opportunities for getting involved.

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Programme:

12 pm Introductory talk Translational Neuroscience for Chronic Neurological Disorders by Director, Professor Dame Pamela Shaw

12:20 Join us for a buffet lunch and networking opportunity in the lobby

12:45 Advanced Medical Imaging for Neurology

by Professor Iain Wilkinson

1 pm Do Virtual Patients see Electric Doctors?

by Professor Marco Viceconti

1:15 Group activities

We will invite attendees to join groups to be guided through 4 activities

2:15 Teas, Coffees, and festive refreshments

2:30 Have your say in an Ask the Audience live polling research involvement exercise with Professor Chris McDermott

2:45 3 pm

Meet Patient and Public Involvement organisers, reclaim travel expenses and exchange contact details if you wish

Close

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Advanced Medical Imaging for Neurology

New medical scanning techniques will

support how we can diagnose patients earlier

and get conclusive results in trials for new

treatments. Find out what we are developing

and what the future of medical imaging may

look like in 5 years’ time.

Professor Iain Wilkinson

Translational Neuroscience for Chronic

Neurological Disorders

My talk introduces the ways in which we are

addressing our main research areas of Motor

Neurone Disease, Parkinson’s Disease,

Dementia, Multiple Sclerosis, and Stroke

Professor Dame Pamela Shaw

Do Virtual Patients see Electric Doctors?

Computer models and simulations can to help

diagnose, manage and predict better

treatments for neurological diseases. In Silico

(computerized) medicine has the goal of

speeding up the process of finding more

effective therapies. By gathering

comprehensive biological data we aim to build

virtual patients to improve clinical trial design.

Professor Marco Viceconti

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Group Activities

If you turn your name badge over you will find a

picture. Our friendly ushers and trainees will help

to take you around these 4 activities in groups

during the next hour.

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What is a genome? What is genomic

sequencing? And how will these things help our

research into neurological disorders? Members

of our Genomic Medicine and Bioinformatics,

and Motor Neurone

Disease research teams will use

the Genomics Education

Programme game to help to

explain the era of genomic

medicine we are living in and ask

you what you think about it.

Drs Dennis Wang, Stephanie

Shepheard and Mark Dunning

Play the Genomics Game

Understanding people's experiences through

creativity: Introducing The KAWA (river of life) Model

In this model the river is your life

journey, the boulders are life

circumstances. The art work example I

created to the left represents a Multiple

Sclerosis (MS) diagnosis as a large

boulder and goes on to depict my

experience with HSCT (hematopoietic

stem cell transplantation) therapy. The

Model can be applied to any journey.

I’m using it to collect people’s

experience with HSCT for relapsing

remitting Multiple Sclerosis in my own

research.

Colette Beecher

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Wearable Sensors to measure

movement disorders

‘Tap vs Cap’ can you tell the difference between tap

water and bottled in a randomized doubled-blind

mock trial?

Would you like to know more about

clinical trials? This session aims to

help understanding about

randomization and double-blind trials

(perhaps cross-over design too, if

there’s time). Learn what these

words mean through a simple water

taste test, conducted by members of

the Sheffield Teaching Hospitals

Clinical Research and Innovation

Office team.

Dan Lawrence, Jodie Keyworth, Alisha Patel and Jennie Smith

Many neurological disorders carry a hallmark of

changes in gait and other movements.

Researchers from The Insigneo Institute for in

silico Medicine will demonstrate how movement

can be tracked objectively to help monitor

changes over time and in response to

treatment. Would you wear these around your

home to be monitored for movement changes?

Drs Claudia Mazza and Lorenza Angelini

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Contact Details

If you would like to find out more about patient and

public involvement in research please contact one

of the co-ordinators listed here:

NIHR Sheffield Biomedical Research Centre Laura Evans [email protected] 0114 222 2268

Sheffield Motor Neurone Disorders Research Advisory Group Annette Taylor [email protected] 0114 222 2289

NIHR Sheffield Clinical Research Facility Liz Ralph [email protected] 0114 271 5114

South Yorkshire Dementia Research Advisory Group Jane Mckeown [email protected] 0114 222 2071

Parkinson’s UK Anna-Louise Smith [email protected]

For further information: Sheffield Teaching Hospitals NHS Foundation Trust Clinical Research and Innovation Office www.sheffieldclinicalresearch.org 0114 226 5938 JACKIE PALMER Clinical Research Administrator

[email protected] [email protected]

Yorkshire and Humber Genomic Medicine Centre PPI Panel Debbie Bearne [email protected] .

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Want to know more?

Follow us on Twitter

@SheffieldBRC

We are developing a public facing website.

Help us to make it better for you by having a

look and giving comments in the online

feedback form

www.sheffieldbrc.nihr.ac.uk

Password: sheffieldBRC

Stay in touch and receive newsletters by

leaving your email or mailing address at the

sign out desk

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Thank You

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The image on the cover is called ‘Dancing

Flowers Astrocytes’ by 2nd Year PhD student,

Noemi Gatto, supervised by Dr Laura Ferraiuolo

at the Sheffield Institute for Translational

Neuroscience. The image was taken with

equipment in our drug screening facility and

shows a type of brain cell called astrocytes.

These cells have been reprogrammed from the

skin cells of patients so we can study them in

close detail and see how potential new

treatments may affect their biology.

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