Standard Operating Procedurefor work withChemical name/class:Toxic Powders and solutions/suspensions of toxic powders (customization required for PHS powders/suspensionsmust complete red sections!C"S #:$ariousP%: "ll &u'e P%s (customization required for PHSs) &ate:(uilding:"ll &u'e (uildings(customization required for PHSs))oom#:&esignated *or' "rea for PHSs:1. Circumstances of +se:Toxic powders include all substances on the particularl hazardous substances listthat are in solid form at room temperature.The procedures outlined below are also recommended for irritatin! powders (nontoxic powders that ma cause respirator or ee irritation if handled onthe open bench). See the separate S"P for nanomaterials (re!ardless of the toxicit of the parent material).For toxic powders/suspensions on the PHS list, you must list circumstances of use, including concentration and quantity. #. Potential Hazards: $onsult the Safet %ata Sheet (S%S) for the material ou are workin! with. Pa attention to both health and phsical hazards.For toxic powders/suspensions on the list of Particularly Hazardous Substances PHSs!, this section must indicate that the chemical is a PHS and why, and gi"e a general o"er"iew of the hazards. #f PHS powders/suspensions ha"e other hazards associated with their use e.g. $ammable, corrosi"e, reacti"e!, those must also be addressed in this S%P. &lternately, this document may refer to another source of information such as a lab in"entory that includes basic hazard information!.&. ,ngineering Controls: 'f aerosols ma be produced( toxic powders (and an suspensions of toxic powders) must be handled in a chemical fume hood( exhausted biolo!ical safet cabinet with ne!ati)e pressure ductwork( or other exhausted enclosure.*erosols ma be produced durin! an open handlin!of dr powder( and durin! open or pressurized manipulations of suspensions.'t is recommended that labs post this information sheet on +orkin! Safel with Toxic Powders.,. *or' Practice Controls: #f other speci'c written procedures are required for wor( with toxic powders/suspensions on the particularly hazardous substances list, you must list them here or attach a step)by)step procedure. #f no further procedures are needed beyond those listed in this template, you can delete this bullet.! #f animals will be dosed with the chemical including drugs!, state that the S%P for Handling &nimals *osed with +oxic ,hemicals will be followed, including ad"anced noti'cation of the animal facility and room and cage labeling requirements. +hen possible( order the material in liquid form( or purchase in pre-wei!hed amounts( preferabl in a sealed )ial with a septum so that the diluent can be in.ected directl into the )ial. Set up a desi!nated area for work with toxic powders and suspensions thereof( and label it. %etermine a means for decontaminatin! the work area. (%ail H/P* )acuumin! or wet cleanin! methods (with a compatible sol)ent) are required for an work that ma !enerateaerosols. 0ote that H/P* )acuumin! is not recommended for reacti)e materials( as the ma react with other materials collected in the )acuum( or with components of the )acuum itself.) 'f wei!hin! dr powders and the balance cannot be located in a fume hood or 1S$( tare a container then add the material to the container in a hood and seal the container before returnin! to the balance to wei!h the powder. $han!e !lo)es re!ularl (at least e)er two hours) and wash hands at the time of the !lo)e chan!e. 'f usin! a H/P* )acuum( chan!e the 2lter inside a chemical fume hood or biolo!ical safet cabinet. 'f the H/P* )acuum ma be used for incompatible materials( maintain a lo! of )acuum use so that collection of incompatible materials can be a)oided. 3eep containers closed as much as possible. *etermine a means for decontaminating the wor( area for PHS powders/suspensions and list it here. -.g., a mild detergent and water, or another sol"ent may be used ) as long as the method is compatible with the chemical.!4. Personal protecti-e equipment (PP,!: Standard nitrile laborator !lo)es and a full buttoned lab coat with slee)es extendin! to the wrists should be worn when handlin! toxic powders. +hen handlin! suspensions or solutions( choose a !lo)e that is protecti)e a!ainst the sol)ent. 'f splashes ma occur( wear !o!!les. "therwise( wear standard laborator safet !lasses. 'n cases where the arms or torso ma be exposed to liquid suspensions or dr particles( wear T)ek slee)es and5or !owns (or other air-ti!ht non-wo)en textile).6. Transportation and Storage: %r powders must be in sealed shatter-resistant containers durin! transportation. 'f the container is not shatter-resistant( use a secondar container. 'f the material ma be 7ammable( reacti)e( or explosi)e( keep awa from heat and open 7ame. 3eep toxic powders awa from an incompatible materials.8. *aste &isposal: 9nwanted toxic powders (and suspensions of toxic powders) must be disposed of followin! our laborator-speci2c chemical h!iene plan( %uke 9ni)ersit:s $hemical +aste Polic and the ;aborator $hemical +aste 1>-6=,-&1&6 for medical ad)ice on occupational chemical exposures.?or an actual chemical exposure ?lush exposed ees or skin with water for at least 14 minutes( then seek medical attention. ?or situations with risk of inhalation exposure (includin! spills outside of a chemical fume hood)( remo)e all persons from the contaminated area and contact the "/S" spill team. $all >11 from a campus phone or >1>-6=,-#,,, from an phone to request assistance if needed. $ontact /mploee "ccupational Health and +ellness at >1>-6=,-=114 for exposure-related ad)ice.The work-related in.ur or illness report found at@ http@55www.hr.duke.edu5bene2ts5medical5workcomp5report.phpshould be completed within #, hours. ?ollow-up medical attention should be sou!ht throu!h %uke /mploee "ccupationalHealth and +ellness (>1>-6=,-&1&6).>. Spill Procedure: Spills of dr toxic powders outside of a chemical fume hood or other enclosure should be referred to the "/S" spill response team b callin! >11 from a campus phone or >1>-6=,-#,,, from an phone. Spills of liquid suspensions should be absorbed with a suitable absorbent. *fterwards( wet-wipe the aAected area three times. Place all absorbent and PP/ into a ba! and seal( then mana!e as chemical waste. ?or spills of dr powders in a chemical fume hood or other enclosure( or )er small spills outside a chemical fume hood( wipe up the powder usin! a cloth dampened with a suitableabsorbent( (determined in ad)ance) or wet the powder with a suitable absorbent and then wipe with a dr cloth. $onsider usin! electrostatic micro2ber cleanin! cloths( especiall if the powder is likel to carr an electrostatic char!e. *lternatel (or in addition)( a H/P* )acuum (preferabl with electrostatic-char!e-neutralization features) ma be used for cleanin! the spill (but do not use the )acuum for cleanin! incompatible materials). 1>-6=,-#8>, with questions).1B.Training of personnel: *ll personnel are required to complete the online Ceneral ;ab Safet session thru the "/S" website.This session includes an introduction to !eneral chemical safet. Trainin! on the speci2c procedures is required for all personnel workin! with these materials( and must be documented (topics co)ered( date( emploee names and si!natures). *ll personnel shall read and full adhere to the laborator-speci2c S"P for toxic powders( and shall document that the ha)e read it b si!nin! and datin! the S"P..% ha-e read and understand this SOP/ % agree to full0 adhere to its requirements/12ast 3irst &u'e %& Signature &ate