sunday 3 february 2013 2013 - final p… · sunday 3 february 2013 13:00 – 15:00 . australian...

SUNDAY 3 FEBRUARY 2013

13:00 – 15:00

AUSTRALIAN BRAIN BEE CHALLENGE NATIONAL FINAL

Location: Plenary Hall 2 15:00 – 15:30

AUSTRALIAN BRAIN BEE CHALLENGE AWARDS Location: Plenary Hall 2 15:00 – 20:00 REGISTRATION Location: Main Foyer 17:00 – 17:15

OPENING OF CONFERENCE A/Prof James Bourne, Chair, ANS 2013 Professor John Rostas, President ANS

Location: Plenary Hall 2

SUNDAY 3 FEBRUARY 2013

17:15 – 18:15 PLENARY 1

OVERSEAS PLENARY LECTURE Chair: Professor John Rostas, President ANS University of Newcastle, NSW Location: Plenary Hall 2

PLE-SUN-01 Elucidating receptor tyrosine kinase-dependent signaling in

neural circuit assembly and plasticity Ip, Nancy (The Hong Kong University of Science and

Technology, Hong Kong)

Professor Nancy Ip

Professor Nancy Ip is currently the Dean of Science, Chair Professor of the Division of Life Science, and Director of the State Key Laboratory of Molecular Neuroscience at The Hong Kong University of Science and Technology (HKUST). She received her PhD degree in Pharmacology from Harvard Medical School, and was Senior Staff Scientist at Regeneron Pharmaceuticals

Inc., New York. Since joining HKUST in 1993, she has served as Associate Dean of Science (1998-2005), Director of the Biotechnology Research Institute (1996-2008), and Head of Biochemistry Department (2000-2009). Professor Ip is a world-renowned neuroscientist with primary interest in brain development and drug discovery for neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. She is well known for her discoveries in the biology of neurotrophic factors, which are proteins that promote the survival, development and maintenance of neurons in the nervous system. She is also internationally recognized as a leader in elucidating the molecular signaling mechanism at synapses, where nerve cells communicate. Given the association of synaptic dysfunction with the pathophysiology of neurodegenerative diseases, her findings provided important clues for the development of therapeutics for these disorders.

18:15 – 20:00 WELCOME MIXER/EXHIBITION Location: Main Foyer

MONDAY 4 FEBRUARY 2013

From 07:30 REGISTRATION Location: Main Foyer 08:30 - 09:30 PLENARY 2

LAWRIE AUSTIN PLENARY LECTURE Chair: Professor Pankaj Sah, Queensland Brain Institute, QLD Location: Plenary Hall 2 PLE-MON-02 Colour vision, colour blindness, and importance of an eye for

detail Martin, Paul R. (University of Sydney, NSW)

Professor Paul Martin

Paul R. Martin received his PhD in Physiology at Sydney in 1986. Following postdoctoral work in Germany, in 1992 he joined Faculty at the University of Sydney. From 2003 to 2010 he was Director of Research at the National Vision Research Institute of Australia and the University of Melbourne. He returned to Sydney in 2010 to take up his current appointment as Professor of Experimental Ophthalmology. Paul's abiding research interest is signal processing in nervous

systems. His research programs have addressed how signals from receptors in the eye are fed into separate brain pathways which underlie the red-green and blue-yellow axes of colour vision. Because defects in colour vision are an early sign of blinding diseases such as glaucoma, basic experiments such as these can improve our understanding of visual dysfunction, as well as revealing the basis of the colour sensations which so enrich our perception of the world. Results of these scientific experiments have been published in over 70 papers in scientific journals and several textbook chapters.

09:30 – 10:00 MORNING TEA / EXHIBITION / POSTERS Location: Main Foyer


10:00 – 12:00 SYMPOSIUM 1

TRANSLATIONAL NEUROSCIENCE SYMPOSIUM A Special Symposium of the ANS 2013 Local

Organising Committee Sponsored by Vice Chancellor's Fund, Monash University

Chair: A/Prof James Bourne, Chair ANS 2013 Australian Regenerative Medicine Institute, VIC Location: Plenary Hall 2 10:00 SYM-01-01 Translational research in Parkinson's disease (PD) Halliday, Glenda (Neuroscience Research Australia) 10:30 SYM-01-02 The translation of bionics into clinical tools Cook, Mark (St Vincent's Hospital Melbourne, VIC) 11:00 SYM-01-03 The translation of potential new drugs affecting endocytosis Robinson, Phil*, McCluskey, A. and O'Brien, T. (*Children's

Medical Research Institute, NSW) 11:30 SYM-01-04 Attentional asymmetry as a predictor of stimulant response in

ADHD Bellgrove, Mark (Monash University, VIC)


10:00 – 12:00 SYMPOSIUM 2

NEUROINFLAMMATION Chair: Professor Louise Nicholson, University of Auckland, NEW ZEALAND Location: Meeting Room 105 10:00 SYM-02-01 Human studies defining the cellular and tissue responses to

Alzheimer proteins Shepherd, Claire (Neuroscience Research Australia, NSW) 10:30 SYM-02-02 TAM receptor signalling, neuroinflammation and

demyelination Field, Judith*, Ma, G.Z.M., Foo, G., Jordan, M., Johnson,

L.J., Stankovich, J., Baxter, A., Butzkueven, H., Kilpatrick, T.J. and Binder, M.D. (*Florey Institute of Neuroscience and Mental Health, VIC)

11:00 SYM-02-03 Low nitric oxide bioavailability is a central mediator of

cerebral malaria pathogenesis van der Heyde, H.C. (La Jolla Infectious Disease Institute,

USA) 11:30 SYM-02-04 Connexon roles in neuroinflammation and vascular leak Green, Colin (University of Auckland, New Zealand)


10:00 – 12:00 ORAL 1

SENSORY SYSTEMS I: AUDITORY Chair: Professor Tony Paolini, RMIT University, VIC Location: Meeting Room 103 10:00 ORAL-01-01 Multisensory integration of visual and auditory rate

information in older adults McKendrick, Allison*, Brooks, C.J., Anderson, A.J., Roach,

N.W. and McGraw, P.V. (*University of Melbourne, VIC) 10:15 ORAL-01-02 What factors determine the perceived complexity of

commonplace sounds? Burns, Tom*, Mokri, Y. and Rajan, R. (*Monash University,

VIC) 10:30 ORAL-01-03 The effect of contralateral stimulation on cochlear amplifier

performance Froud, Kristina*, Wong, A.C.Y. and Housley, G.D.

(*University of New South Wales, NSW) 10:45 ORAL 01-04 Primary auditory cortex of anaesthetized marmosets:

neuronal sensitivity to interaural level differences for natural vocalizations

Lui, Leo*, Mokri, Y., Rosa, M.G.P. and Rajan, R. (*Monash University, VIC)


11:00 ORAL-01-05 Visual and auditory perception deficits suggest altered neural

integration function in psychosis Carter, Olivia*, Bennett, D., Nash, T., Arnold, S., Brown, L.,

Cai, R.Y., Allen, Z., Dluzniak, A., McAnally, K. and Sundram, S. (*University of Melbourne, VIC)

11:15 ORAL-01-06 Spatial selectivity of responses of caudolateral auditory cortex

fields Mokri, Yasamin*, Lui, L., Reser, D., Rosa, M.G.P. and

Rajan, R. (*Monash University, VIC) 11:30 ORAL-01-07 Cochlear gene expression analysis in response to noise stress

in mice Cederholm, Jennie*, Froud, K.E. and Housley, G.D.

(*University of New South Wales, NSW) 11:45 ORAL-01-08 Cell-based neurotrophin delivery for auditory neuron survival

in deafness Gillespie, Lisa*, Zanin, M.P. and Shepherd, R.K. (*Bionics

Institute, VIC)


10:00 – 12:00 ORAL 2

AUTONOMIC AND MOTOR SYSTEMS I Chair: Dr Stuart Mazzone, University of Queensland, QLD Location: Meeting rooms 101/102 10:00 ORAL-02-01 Postural control in young female FMR1 premutation carriers Kraan, Claudine*, Hocking, D., Bradshaw, J., Georgiou-

Karistianis, N. and Cornish, K. (*Monash University, VIC) 10:15 ORAL-02-02 Consistent inter-individual differences in the cardiovascular

responses to sustained muscle pain in human subjects Fazalbhoy, Azharuddin*, Birznieks, I. and Macefield, V.G.

(*Neuroscience Research Australia, NSW) 10:30 ORAL-02-03 Using optogenetic stimulation to understand the function of

C3 neurons Menuet, Clement*, Bassi, J.K., Connelly, A. and Allen, A.M.

(*University of Melbourne, VIC) 10:45 ORAL-02-04 Metallo-complexes as therapeutics in mouse models of

amyotrophic lateral sclerosis McAllum, Erin*, Lim, N., Roberts, B.R., Paterson, B.M.,

Hickey, J.L., Barnham, K.J., Donnelly, P.S., Liddell, J.R., White, A.R. and Crouch, P.J. (*University of Melbourne, VIC)

11:00 ORAL-02-05 Central pathways for sweating in humans Farrell, Michael*, Trevaks, D., Taylor, N.A., Lambert, G.W.

and McAllen, R.M. (*Florey Institute of Neuroscience and Mental Health, VIC)


11:15 ORAL-02-06 Use of illicit stimulant drugs is associated with long term

changes in human motor circuitry Flavel, S.C., White, J.M. and Todd, Gabrielle* (*University

of South Australia, SA) 11:30 ORAL-02-07 Aldosterone-sensitive neurons within the solitary tract nucleus

(NTS) receive direct primary afferent input Guo, H. and McDougall, Stuart* (*Florey Institute of

Neuroscience and Mental Health, VIC) 11:45 ORAL-02-08 Prefrontal cortex mediates respiratory activation in response

to brief alerting stimuli and stress Bondarenko, Evgeny*, Averell, L., Hodgson, D.M. and

Nalivaiko, E. (*University of Newcastle, NSW)


10:00 – 12:00 ORAL 3

SYNPATIC TRANSMISSION AND EXCITABILITY Chair: Dr Atomu Sawatari, University of Sydney, NSW Location: Meeting Room 106 10:00 ORAL-03-01 AAV-mediated overexpression of cannabinoid receptor

interacting protein Crip1a decreases seizure activity in mice Guggenhuber, S., Schmitz, N., Elphick, M.R., Alpar, A.,

Harkany, T., Harasta, A.E., Monory, K., Kaiser, N., Lutz, B. and Klugmann, Matthias* (*University of New South Wales, NSW)

10:15 ORAL-03-02 Human auxiliary subunits KCTD12 and KCTD16

differentially modulate GABA(B) receptor function Li, Melody*, Milligan, C., Reid, C., Wang, H., Hopkins, S.C.

and Petrou, S. (*Florey Institute of Neuroscience and Mental Health, VIC)

10:30 ORAL-03-03 Human Cav2.3 (R-type) calcium channels are inhibited by

analgesic α-conotoxin Vc1.1 via a voltage-independent pathway involving c-src tyrosine kinase

Berecki, Geza*, McArthur, J.R. and Adams, D.J. (*RMIT University, VIC)

10:45 ORAL-03-04 Cannabinoid receptor interacting protein (CRIP1a) modulates

CB1 receptor-mediated downstream signalling events in neuroblastoma X glioma cells

Khajehali, Elham*, Exintaris, B., White, P., Haynes, J.M. and Malone, D.T. (*Monash University, VIC)


11:00 ORAL-03-05 N-arachidonoyl dopamine mobilizes calcium via human CB1

and CB2 receptors without inhibiting adenylyl cyclase: evidence of biased agonism

Redmond, William*, Breen, C., Cawston, E., Glass, M. and Connor, M. (*Macquarie University, NSW)

11:15 ORAL-03-06 Liquid state computation in cholinergically modulated cortical

networks Stiefel, Klaus* and van Schaik, A. (*University of Western

Sydney, NSW) 11:30 ORAL-03-07 Examination of voltage-activated currents elicited by external

electrical stimulation Cameron, Morven*, Suaning, G.J., Lovell, N.H. and Morley,

J.W. (*University of Western Sydney, NSW) 11:45 ORAL-03-08 Patient autoantibodies reveal the role of muscle specific

kinase in maintaining the mature neuromuscular junction Morsch, Marco*, Reddel, S.W., Ghazanfari, N., Toyka, K.V.

and Phillips, W.D. (*University of Sydney, NSW)


10:00 – 12:00 ORAL 4

LIMBIC, NEUROENDOCRINE AND OTHER SYSTEMS Chair: Professor Mark Sleeman, Monash University, VIC Location: Meeting Room 104 10:00 ORAL-04-01 Inter-generational sex-specific transmission of an anxiety

phenotype due to sire cocaine exposure White, Samantha*, Vassoler, F.M., Schmidt, H.D., Sadri-Vakili, G. and Pierce, R.C (*University of

Pennsylvania, USA) 10:15 ORAL-04-02 Modulation of feeding by chronic viral expression of a

relaxin-3 peptide agonist in rat hypothalamus Ganella, Despina*, Callander, G.E., Ma, S., Bye, C.,

Gundlach, A.L. and Bathgate, R.A.D. (*Florey Institute of Neuroscience and Mental Health, VIC)

10:30 ORAL-04-03 Interactions between GnRH, Kisspeptin and GnlH neurons in

the equine hypothalamus McGrath, Briony*, Norman, S.T. and Scott, C.J. (*Charles

Sturt University, NSW) 10:45 ORAL-04-04 Enterochromaffin cells release 5-HT with synaptic kinetics Raghupathi, Ravi*, Zelkas, L., Duffield, M., Spencer, N. and

Keating, D. (*Flinders University of South Australia, SA)


11:00 ORAL-04-05 Long term alterations in gene expression in limbic regions and

adrenal tyrosine hydroxylase activity induced by a neonatal immune challenge are associated with an anxiety-like phenotype

Sominsky, Luba*, Ong, L.K., Moussavi, M., Dunkley, P.R., Dickson, P.W. and Hodgson, D.M. (*University of Newcastle, NSW)

11:15 ORAL-04-06 Orexin neurons are hyporesponsive to stress following

maternal separation James, Morgan*, Campbell, E.J., Sominsky, L., Hodgson,

D.M. and Dayas, C.V. (*University of Newcastle, NSW) 11:30 ORAL-04-07 Lactation-induced changes in phospho-STAT5 and phospho-

ERK signalling in tuberoinfundibular dopaminergic neurons Kirk, S., Grattan, D.R. and Bunn, Stephen* (*University of

Otago, New Zealand) 11:45 ORAL-04-08 Leptin signalling in the dorsal vagal complex and ventrolateral

medulla with age and high-fat diet induced obesity Bell, Chris*, Yu, Y.H., Szabo, A. and Huang, X.F.

(*University of Wollongong, NSW)

12:00 – 12:30 LUNCH/EXHIBITION (Lunch provided) Location: Main Foyer

12:30– 14:30 POSTER SESSION A / EXHIBITION 12:30 – 13:30 Presenters of odd numbered posters in attendance 13:30 – 14:30 Presenters of even numbered posters in attendance Location: Main Foyer


14:30 – 16:30 SYMPOSIUM 3

STEM-CELL DERIVED NEURONS: FROM DISEASE MODELS TO THERAPIES

Chairs: Dr Mirella Dottori, University of Melbourne, VIC Dr Jenny Gunnersen, University of Melbourne, VIC Location: Plenary Hall 2 14:30 SYM-03-01 Using iPS cells to study autism spectrum disorders Dolmetsch, Ricardo*, Pasca, S., Shchlegovitov, A., Yazawa,

M., Portmann, T., Mao, R., Krawisz, A., Bernstein, J. and Hallmayer, J. (*Stanford University, USA)

15:00 SYM-03-02 A cellular model for sporadic ALS using patient-derived

induced pluripotent stem cells Javaherian, Ashkan (iPierian Inc, USA) 15:30 SYM-03-03 Challenges for stem cells to functionally repair the deaf

cochlea Nayagam, Bryony*, Needham, K., Hyakumura, T.,

Gunewardene, N. and Dottori, M. (*University of Melbourne, VIC)

16:00 SYM-03-04 Challenges towards stem cell therapy for Parkinson's disease Takahashi, Jun (Kyoto University, Japan)


14:30 – 16:30 SYMPOSIUM 4

MOLECULAR PATHOLOGY OF MOTOR NEURODENGENERATIVE DISORDERS

Chair: Professor Phil Beart, Florey Neuroscience Institutes, VIC Location: Meeting Room 105 14:30 SYM-04-01 Motor neuron degeneration in spinal muscular atrophy Talbot, Kevin (University of Oxford, UK) 15:00 SYM-04-02 Newly identified familial ALS genes provide fresh insights

into pathogenic mechanisms Williams, K.L, Solski, J.A., Yang, S., Warraich, S.,

Nicholson, G.A. and Blair, Ian* (*Australian School of Advanced Medicine, Macquarie University, NSW)

15:30 SYM-04-03 A central and early role for disruption of COPII-mediated ER-

Golgi trafficking in amyotrophic lateral sclerosis Soo, K.Y., Farg, M.A., Halloran, M., Sundarmoorthy, V.,

Walker, A.K., Nagley, P.N., Turner, B.J., Horne, M.K. and Atkin, Julie* (*La Trobe Institute for Molecular Science, VIC)

16:00 SYM-04-04 Endosome-lysosome system dysregulation in amyotrophic

lateral sclerosis Sheean, R.K., Aumann, T.D., Coleman, B.M., Hill, A.F.,

Atkin, J.D., Horne, M.K. and Turner, Bradley* (*Florey Institute of Neuroscience and Mental Health, VIC)


14:30 – 16:30 SYMPOSIUM 5

FAONS SYMPOSIUM I: “STRESS AND DRUG ADDICTION”

Supported by: Federation of Asian Oceanian Neuroscience Societies (FAONS)

International Brain Research Organization (IBRO) Pratt Foundation

Seong-Seng Tan, Melbourne, Australia Queensland Brain Institute, University of Queensland

Chinese Neuroscience Society Chairs: A/Prof Peter Dodd, University of Queensland, QLD Professor Andrew Lawrence, Florey Institute of

Neuroscience & Mental Health, VIC Location: Meeting Room 106 14:30 SYM-05-01 Dissecting the central stress response using site-specific

genetic manipulation in adult mice Chen, Alon (Weizmann Institute of Science, Israel) 15:00 SYM-05-02 Hypothalamic mechanisms promoting and preventing drug

seeking McNally, Gavan (University of New South Wales, NSW) 15:30 SYM-05-03 Behavioral manipulation of US specific reconsolidation to

erase emotion memory Zhao, L., Liu, J., Shi, J., Xue, Y., Suo, L., Chai, B., Zhang, Y.,

Yang, C. and Lu, Lin* (*Peking University, China) 16:00 SYM-05-04 Stress, culture and alcoholism Kim, Sung-Gon (Pusan National University, Korea)


14:30 – 16:30 ORAL 5

NEURAL ENGINEERING/BIONICS Sponsored by The Finkel Foundation

Chair: A/Prof Steven Petrou, Florey Institute of Neuroscience &

Mental Health, VIC Location: Meeting Room 103 14:30 ORAL-05-01 Recreating vision with a retinal prosthesis Wong, R.C.S., Garrett, D., Grayden, D.B., Savage, C., Apollo,

N., Cloherty, S.L., Ibbotson, M.R., Prawer, S., Burkitt, A.N. and O'Brien, Brendan* (*National Vision Research Institute, VIC)

14:45 ORAL-05-02 A bidomain approach to predict the activation map of the

retina in visual prostheses Meffin, H., Tahayori, Bahman*, Grayden, D.G. and Burkitt,

A.N. (*University of Melbourne, VIC) 15:00 ORAL-05-03 Impedance variation and stimulation efficacy of chronic

cortical implants in rat motor cortex Wang, Chun*, Brunton, E., Haghgooie, S., Cassells, K. and

Rajan, R. (*Monash University, VIC) 15:15 ORAL-05-04 Spatiotemporal interactions in the visual cortex using paired

electrical stimulation of the retina Cicione, Rosemary*, Shivdasani, M.N., Fallon, J.B.,

Rathbone, G.D. and Williams, C.E. (*Bionics Institute, VIC)


15:30 ORAL-05-05 Doped conducting polymer coated neural recording electrodes Harris, Alex*, Morgan, S.J., Chen, J., Kapsa, R.M.I.,

Wallace, G.G. and Paolini, A.G. (*La Trobe University, VIC) 15:45 ORAL-05-06 Suprachoriodal electrical stimulation: assessing efficacy of

repetitive electrical stimulation John, Sam*, Shivdasani, M.N., Fallon, J.B., Rathbone, G. and

Williams, C.W. (*Bionics Institute, VIC) 16:00 ORAL-05-07 Promoting engraftment of transplanted neural stem

cells/progenitors using biofunctionalised electrospun scaffolds Wang, T., Nisbet, D.R. and Parish, Clare* (*Florey Institute

of Neuroscience and Mental Health, VIC) 16:15 ORAL-05-08 Epiretinal stimulation using ultrananocrystalline diamond

electrodes Shivdasani, Mohit*, Garrett, D.J., Nayagam, D.A.X., Allen,

P.J., Saunders, A., McPhedran, M., Burns, O., Meffin, H., Prawer, S. and Shepherd, R.K. (*Bionics Institute, VIC)


14:30 – 16:30 ORAL 6

DISORDERS AND INJURY OF THE NERVOUS SYSTEM I: ALZHEIMERS

Chair: A/Prof Elizabeth Coulson, Queensland Brain Institute,

QLD Location: Meeting Rooms 101/102 14:30 ORAL-06-01 HDAC6 mutations rescue human tau-induced microtubule

defects in Drosophila Xiong, Y., Zhao, K., Wu, J.X., Jin, S. and Zhang, Yong*

(*Institute of Genetics and Developmental Biology, China) 14:45 ORAL-06-02 Regiospecific loss of essential sphingolipids in the early

stages of Alzheimer's disease Kain, Nupur*, Couttas, T.A., Garner, B. and Don, A.S.

(*University of New South Wales, NSW) 15:00 ORAL-06-03 Biometal homeostasis in childhood neurodegenerative disease Grubman, Alex*, Kanninen, K., Duncan, C., Lidgerwood,

G., Choo, X.Y., Caragounis, A., Moujalled, D., Liddell, J., Crouch, P.J. and White, A.R. (*University of Melbourne, VIC)

15:15 ORAL-06-04 Synaptic proteome in Alzheimer's disease Chang, Rachel*, Etheridge, N., Nouwens, A. and Dodd, P.

(*University of Queensland, QLD)


15:30 ORAL-06-05 RCAN1 over-expression results in iron accumulation and

increased oxidative stress in the mouse brain Corlett, A., Czerwinska, H., Morianos, C., Dubach, D.,

Finkelstein, D.I., Lawen, A. and Pritchard, Melanie* (*Monash University, VIC)

15:45 ORAL-06-06 Sortilin interacts with amyloid precursor protein and regulates

its lysosomal trafficking and processing Yang, X.F., Virassamy, B., Vijayaraj, S.L., Lim, Y.,

Saadipour, K., Wang, Y.J., Zhong, J.H., Morales, C.R. and Zhou, Xin-Fu* (*University of South Australia, SA))

16:00 ORAL-06-07 Estren attenuates beta amyloid-induced lesions of cortical

cholinergic projections in vivo Kwakowsky, Andrea*, Kim, S.H. and Abraham,

(*University of Otago, New Zealand) 16:15 ORAL-06-08 Guinea pigs and zebrafish for investigation of Alzheimer's

disease genetics Sharman, M.J., Moussavi Nik, S.H., Chen, M., Ong, D.,

Wijaya, L., Laws, S.M., Newman, M., Verdile, G., Martins, R.N. and Lardelli, Michael* (*University of Adelaide, SA)


14:30 – 16:30 ORAL 7

COGNITION, LEARNING AND BEHAVIOUR I Chair: Dr Olivia Carter, University of Melbourne, VIC Location: Meeting Room 104 14:30 ORAL-07-01 The effects of high fat and sugar diets on cognition in the rat Beilharz, Jessica*, Maniam, J., Morris, M.J. and Westbrook,

R.F. (*University of New South Wales, NSW) 14:45 ORAL-07-02 Suboccipital intracranial ERP recordings for visual objects:

electrophysiological evidence for separate specialized areas Darcey, Terrance*, Hughes, H.C., Williamson, P.D.,

Thadani, V.M. and Roberts, D.W. (*Dartmouth-Hitchcock Medical Center, USA)

15:00 ORAL-07-03 Frontal lobe contributions to cognitive flexibility and control Mansouri, Farshad*, Buckely, M.J. and Tanaka, K.

(*Monash University, VIC) 15:15 ORAL-07-04 Optogenetic analysis of the cerebellar circuits involved in

zebrafish motor learning Thompson, Andrew*, Staykov, E. and Scott, E.K.

(*University of Queensland, QLD) 15:30 ORAL-07-05 RXFP3 deletion enhances ethanol-induced ataxia and reduces

ethanol preference following forced swim stress in C57BL/6J mice

Walker, Andrew*, Smith, C.M., Gundlach, A.L. and Lawrence, A.J. (*Florey Institute of Neuroscience and Mental Health, VIC)


15:45 ORAL-07-06 Cocaine self-administration during adolescence leads to

diminished primed - but exaggerated cue-induced reinstatement compared to adulthood

Zbukvic, I., Luikinga, S., Lawrence, A.J. and Kim, Jee Hyun* (*Florey Institute of Neuroscience and Mental Health, VIC)

16:00 ORAL-07-07 MicroRNA regulation of olfactory learning and memory in

honeybees Cristino, Alex*, Reinhard, J., Barchuk, A.R., Biergans, S.,

Freitas, F.P., Zhao, Z., Simoes, Z.L.P. and Claudianos, C. (*University of Queensland, QLD)

16:15 ORAL-07-08 Measuring the level of consciousness based on the amount of

integrated information Tsuchiya, Nao*, Oizumi, M., Yanagawa, T., Amari, S. and

Fujii, N. (*Monash University, VIC)

16:30 – 17:00 AFTERNOON TEA / EXHIBITION / POSTERS Location: Main Foyer


17:00 – 18:00

PLENARY 3

ECCLES PLENARY LECTURE

Chair: Professor Louise Nicholson, University of Auckland, NEW ZEALAND


PLE-MON-03 Deciphering the epilepsy genome and its impact on clinical practice Scheffer, Ingrid (Florey Institute of Neuroscience and Mental Health, VIC)

Professor Ingrid Scheffer

Professor Ingrid Scheffer is a paediatric neurologist and epileptologist at the University of Melbourne, Australia. Her work together with Professor Sam Berkovic, with the molecular geneticists at the Women’s and Children’s Hospital, Adelaide, has led the field

of epilepsy genetics research over the last 21 years. This collaboration resulted in identification of the first epilepsy gene and more than half of the genes currently known. Professor Scheffer has described many novel epilepsy syndromes and continues to work on genotype–phenotype correlation. Professor Scheffer’s research interests include genetics of epilepsy, epilepsy syndrome classification, and genetics of autism spectrum disorders and speech and language disorders. She was awarded the 2007 American Epilepsy Society Clinical Research Recognition Award, the 2009 Eric Susman Prize from the Royal Australasian College Of Physicians and she was awarded the L’Oreal-UNESCO Women in Science Laureate for the Asia-Pacific region for 2012. Professor Scheffer is currently Chair of the International League Against Epilepsy Commission for Classification and Terminology

TUESDAY 5 FEBRUARY 2013

08:00 – 10:00 SYMPOSIUM 6

NEURAL BASIS OF VISUAL CORTICAL ORIENTATION SELECTIVITY, 50 YEARS AFTER HUBEL & WIESEL’S

HYPOTHESIS Chairs: Professor Bogdan Dreher, University of Sydney, NSW Professor Michael Ibbotson, National Vision Research

Institute, VIC Location: Plenary Hall 2 08:00 SYM-06-01 Inhibition, spike threshold, and stimulus selectivity in primary

visual cortex Priebe, Nicholas (University of Texas at Austin, USA) 08:30 SYM-06-02 Orientation and direction specificity in the cat visual cortex -

dissecting the intracortical network Eysel, Ulf (Ruhr-University Bochum, Germany) 09:00 SYM-06-03 Multiple mechanisms - subcortical and cortical - in the

generation of striate cortical orientation selectivity Vidyasagar, Trichur (University of Melbourne, VIC) 09:30 SYM-06-04 Circuits that create tuned responses in visual cortex Sur, Mriganka (Massachusetts Institute of Technology,

USA)


08:00 – 10:00 SYMPOSIUM 7

NOVEL THERAPIES FOR THE TREATMENT OF EPILEPSY Chairs: Dr Kim Powell, University of Melbourne, VIC Dr Chris Reid, Florey Institute of Neuroscience & Mental

Health, VIC Location: Meeting Room 105 08:00 SYM-07-01 Abolishment of burst-firing-mediated excitability in thalamic

neurons and absence seizures by a novel T-type calcium channel blocker

Snatch, Terry (University of British Columbia, Canada) 08:30 SYM-07-02 Reduced pyramidal neuron dendritic arborisation underlies

enhanced excitability in a NAVβ1 model of severe epilepsy is sensitive to disease mechanism based therapy

Petrou, Steven*, Reid, C.A., Leaw, B., Richards, K.L., Wimmer, V., Hill, E., Scheffer, I.E., Berkovic, S.F., Low, J. and Lerche, H. (*Florey Institute of Neuroscience & Mental Health, VIC)

09:00 SYM-07-03 Environmental stimulation mitigates epilepsy progression: a

novel therapeutic strategy Jones, Nigel (University of Melbourne, VIC) 09:30 SYM-07-04 Targeting tau phosphorylation with sodium selenate to impact

on epilepsy Hovens, Christopher*, Liu, S., Jones, N.C., Nguyen, T.,

Corcoran, N.M. and O'Brien, T.J. (*University of Melbourne, VIC)


08:00 – 10:00 SYMPOSIUM 8

NEURAL MECHANISMS OF COGNITIVE BRAIN TRAINING

Chair: A/Prof Michael Valenzuela, Brain and Mind Research

Institute, NSW Location: Meeting Room 106 08:00 SYM-08-01 Neural correlates of cognitive training in older adults Naismith, Sharon (University of Sydney, NSW) 08:30 SYM-08-02 Training the multitasking brain Dux, P.E. (University of Queensland, QLD) 09:00 SYM-08-03 Effects and correlates of memory training in the adult brain Engvig, Andreas*, Fjell, A.M., Westlye, L.T., Skaane, N.V.,

Dale, A.M., Holland, D. and Walhovd, K.B. (*University of Oslo, Norway)

09:30 SYM-08-04 Timecourse of cognitive, structural and functional responses

to cognitive brain training in at-risk elderly Lampit, Amit*, Suo, C., Kwok, S., Moss, R., Hallock, H.,

Brodaty, H., Naismith, S. and Valenzuela, M. (*University of Sydney, NSW)


08:00 – 10:00 ORAL 8

DISORDERS AND INJURY OF THE NERVOUS SYSTEM II: NEUROTRAUMA

Chair: A/Prof Melinda Fitzgerald, University of Western

Australia, WA Location: Meeting Room 101/102 08:00 ORAL-08-01 Traumatic brain injury: characterisation of behavioural and

electrophysiological deficits 24 hours post-injury Johnstone, Vicky*, Alwis, D., Yan, E. and Rajan, R.

(*Monash University, VIC) 08:15 ORAL-08-02 Modulating aquaporin-4 channels: effects on cerebral oedema

following brain injury Mander, Kim*, Turner, R.J., Thornton, E., Yool, A. and

Vink, R. (*University of Adelaide, SA) 08:30 ORAL-08-03 Type-1 interferon signalling plays a key role in the

exacerbation of neuro-inflammation following traumatic brain injury

Karve, Ila*, Zhang, M., Ates, R., Taylor, J.M. and Crack, P.J. (*University of Melbourne, VIC)

08:45 ORAL-08-04 Developmentally-linked proteomic changes of the spinal cord

of the Monodelphis domestica: response to spinal injury Noor, Natassya*, Steer, D.L., Wheaton, B.J., Ek, C.J.,

Truettner, J.S., Dziegielewska, K.M. and Dietrich, W.D. (*University of Melbourne, VIC)


09:00 ORAL-08-05 Motor function recovery in spinal cord injured rats after

nanoparticles implantation and electromagnetic field exposure Jain, Suman*, Pal, A., Kumar, S., Nag, T.C. and Mathur, R.

(*All India Institute of Medical Sciences, India) 09:15 ORAL-08-06 Does oedema development contribute to raised intrathecal

pressure following traumatic spinal cord injury? Leonard, Anna*, Thornton, E. and Vink, R. (*University of

Adelaide, SA) 09:30 ORAL-08-07 Isoproterenol or norepinephrine treatment modulates

neurogenesis after an endothelin-1 hippocampal stroke model in adult mouse

Codd, Lavinia*, Jhaveri, D.J., Hamlin, A.S. and Bartlett, P.F. (*Queensland Brain Institute, QLD)

09:45 ORAL-08-08 Cellular changes following focal ischemia of the infant and

adult nonhuman primate primary visual cortex Teo, Leon* and Bourne, J.A. (*Monash University, VIC)


08:00 – 10:00 ORAL 9

DEVELOPMENT AND REGENERATION I Chair: Dr Joanne Britto, Florey Institute of Neuroscience &

Mental Health, VIC Location: Meeting Room 103 08:00 ORAL-09-01 14-3-3zeta maintains phosphorylation of NDEL1 to control

neural migration Saleh, Eiman*, Ramshaw, H., Xu, X., Lopez, A.F. and

Schwarz, Q. (*University of Adelaide, SA) 08:15 ORAL-09-02 Phenotypically distinct neural precursor cell populations

generate progeny that have discrete transcriptional profiles in the adult hippocampus

Jhaveri, Dhanisha*, Newcombe, E., Robinson, G., Wray, N. and Bartlett, P. (*Queensland Brain Institute, QLD)

08:30 ORAL-09-03 Adult hippocampal neurogenesis, Rho kinase inhibition and

enhancement of neuronal survival Christie, Kim*, Turbic, A. and Turnley, A.M. (*University of

Melbourne, VIC) 08:45 ORAL-09-04 Neuron-specific alternative splicing is a mechanism for

increasing the diversity of brain wiring proteins Lah, G.J., Carroll, L. and Millard, Sean* (*University of

Queensland, QLD)


09:00 ORAL-09-05 Npas4 regulates the expression of Sox1 in an early neural

progenitor cell population during neural differentiation of mouse embryonic stem cells

Klaric, Thomas*, Thomas, P.Q., Dottori, M., Leong, W.K., Koblar, S.A. and Lewis, M.D. (*University of Adelaide, SA)

09:15 ORAL-09-06 Examining the role of STIM proteins in the developing

nervous system Mitchell, C.B., Hadrill, C.E., Gasperini, R., Small, D.H. and

Foa, Lisa* (*University of Tasmania, TAS) 09:30 ORAL-09-07 Enrichment accelerates PNN formation in the hippocampus Rahman, Tasnim*, O'Connor, A., Leamey, C. and Sawatari,

A. (*University of Sydney, NSW) 09:45 ORAL-09-08 The role of innervation in development of limb muscle

progenitors Hurren, Brad* and Duxson, M.J. (*University of Otago,

New Zealand)


08:00 – 10:00 ORAL 10

AUTONOMIC AND MOTOR SYSTEMS II Chair: Professor John Furness, University of Melbourne, VIC Location: Meeting Room 104 08:00 ORAL-10-01 Reduced dorsal horn neuron activation following intra-colonic

icilin administration Harrington, Andrea* and Brierley, S.M. (*University of

Adelaide, SA) 08:15 ORAL-10-02 Expression of the ghrelin receptor gene in neurons of the

medulla oblongata of the rat Bron, Romke*, Yin, L., Russo, R. and Furness, J.

(*University of Melbourne, VIC) 08:30 ORAL-10-03 Natural stimuli evoke co-ordinated activation of sympathetic,

cardiac, respiratory and motor outputs after disinhibition of neurons in the inferior and superior colliculi

Muller-Ribeiro, Flavia*, Fontes, M.A.P., Dampney, R.A.L. and Goodchild, A.K. (*Macquarie University, NSW)`

08:45 ORAL-10-04 Blockade of epithelial sodium channels (ENaC) reduces

pressure-induced peristalsis in guinea pig intestine Polglaze, Kate*, Lim, C.R., Morgulis, Y., Bertrand, R.L.,

Liu, L. and Bertrand, P.P. (*University of New South Wales, NSW)


09:00 ORAL-10-05 Activity of enteric motor neurons deduced from their

mechanical consequences in isolated rabbit colon Costa, Marcello*, Wiklendt, L., Arkwright, J.W., Spencer,

N.J., Brookes, S.J. and Dinning, P.G. (*Flinders University of South Australia, SA)

09:15 ORAL-10-06 A human model for understanding small bowel motility Sia, Tiong Chen*, Dodds, K., Kyloh, M., Wattchow, D.,

Spencer, N., Brookes, S., Arkwright, J. and Dinning, P.G. (*Flinders University of South Australia, SA)

09:30 ORAL-10-07 A computational model of intrinsic sensory neurons of the gut Chambers, Jordan*, Bornstein, J.C., Gwynne, R.M.,

Koussoulas, K. and Thomas, E.A. (*University of Melbourne, VIC)

09:45 ORAL-10-08 Ataxin-2 interacts with FUS and intermediate-length

polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis

Farg, Manal*, Soo, K., Warraich, S., Sundaramoorthy, V., Blair, I. and Atkin, J. (*La Trobe University, VIC)

10:00 – 10:30 MORNING TEA / EXHIBITION / POSTERS Location: Main Foyer


10:30 – 12:30 SYMPOSIUM 9

DEVELOPMENT OF THERAPEUTICS FOR NEURODEGENERATIVE DISEASES

Chair: Professor Ashley Bush, Mental Health Research Institute,

VIC Location: Plenary Hall 2 10:30 SYM-09-01 Novel multi target neurorestorative anti Alzheimer drugs

with cell cycle activity Youdim, Moussa (Rappaport Family Faculty of Medicine,

Israel) 11:00 SYM-09-02 Novel therapeutic approaches for the neurodegenerative

diseases Barnham, Kevin (Mental Health Research Institute, VIC) 11:30 SYM-09-03 Structural characterization for the design of Alzheimers

disease diagnostics and therapeutics Streltsov, Victor (CSIRO Materials Science and

Engineering & Preventative Health Flagship and CRC for Mental Health, VIC)

12:00 SYM-09-04 Identification and validation of biomarkers for

neurodegenerative diseases Rainey-Smith, Stephanie (Edith Cowan University, WA)


10:30 – 12:30

SYMPOSIUM 10

FAONS SYMPOSIUM II “DEVELOPMENT OF CORTICAL CIRCUITS”

Supported by: Federation of Asian Oceanian Neuroscience Societies (FAONS)

International Brain Research Organization (IBRO) Pratt Foundation

Seong-Seng Tan, Melbourne, Australia Queensland Brain Institute, University of Queensland

Chinese Neuroscience Society

Chairs: Professor Linda Richards, Queensland Brain Institute, QLD

Professor Seong-Seng Tan, Florey Institute of Neuroscience & Mental Health, VIC

Location: Meeting Room 105

10:30 SYM-10-01 Global and crossmodal effects of environmental stimulation of

neural circuit formation in the sensory cortices Zheng, J.-J., Li, S.-J., Zhang, X.-D. and Yu, Xiang* (Institute

of Neuroscience, CAS, China)

11:00 SYM-10-02 Molecular mechanisms involved in regulation of neuronal

migration, cell autonomous and non-cell autonomous Reiner, Orly*, Sapir, T. and Gorelik, A. (*Weizmann

Institute of Science, Israel)

11:30 SYM-10-03 Molecular mechanisms of barrel cortex development Shimogori, Tomomi* and Matsui, A. (*RIKEN Brain

Science Institute, Japan)

12:00 SYM-10-04 Early stress evokes age-dependent biphasic changes in

hippocampal neurogenesis, epigenetic regulation of the BDNF gene, and cognitive behavior

Suri, D., Veenit, V., Sarkar, A., Thiagarajan, D., Kumar, A., Nestler, E.J., Galande, S. and Vaidya, Vidita A.* (*Tata Institute of Fundamental Research, India)


10:30 – 12:30 SYMPOSIUM 11

NOVEL APPROACHES TO UNDERSTANDING THE BRAIN’S CONNECTOME

Chair: A/Prof Andrew Allen, University of Melbourne, VIC Location: Meeting Room 106 10:30 SYM-11-01 Cre-dependent pseudorabies viral approaches for examining

polysynaptic connections Sved, Alan*, Enquist, L.W. and Card, J.P. (*University of

Pittsburgh, USA) 11:00 - SYM-11-02 Mapping the connectome of functionally-identified neurons McMullan, Simon (Macquarie University, NSW) 11:30 SYM-11-03 Cell-selective lentiviruses enable mapping of the projections

of specific neuronal cell groups throughout the CNS Sevigny, Charles*, Bassi, J., Williams, D.A., Anderson, C.R.,

Thomas, W.G. and Allen, A.M. (*University of Melbourne, VIC)

12:00 SYM-11-04 In vivo functional connectomics using fMRI Fornito, Alex (University of Melbourne, VIC)


10:30 – 12:30 ORAL 11

DISORDERS AND INJURY OF THE NERVOUS SYSTEM III: PSYCHIATRIC DISORDERS

Chair: Professor Peter Schofield, Neuroscience Research

Australia, NSW Location: Meeting Room 103 10:30 ORAL-11-01 Sex differences in Reelin/BDNF interactions in the ventral

hippocampus Hill, Rachel*, Wu, Y.W.C., Gogos, A. and van den Buuse,

M. (*Florey Institute of Neuroscience and Mental Health, VIC)

10:45 ORAL-11-02 A cognitive neurome: neuropsychiatric disorders represent an

interconnected molecular system Cristino, A.S., Williams, S., Hawi, Z., An, J.A., Bellgrove,

M.A., Schwartz, C., Costa, L.F. and Claudianos, Charles* (*Queensland Brain Institute, QLD)

11:00 ORAL-11-03 Time-dependent ghrelinergic signaling and hyperphagia

induced by olanzapine Zhang, Qingsheng*, He, M., Wang, H.Q., Lian, J., Deng, C.

and Huang, X.F. (*University of Wollongong, NSW) 11:15 ORAL-11-04 Advances in modeling an endophenotype of schizophrenia in

rodents: mismatch responses to frequency deviants in awake, freely-moving rats

Nakamura, T., Harms, Lauren*, Fulham, W.R., Todd, J., Schall, U., Michie, P.T. and Hodgson, D.M. (*University of Newcastle, NSW)


11:30 ORAL-11-05 Focal adhesion dynamics are altered in schizophrenia Fan, Y., Abrahamsen, G., Mills, R., Calderon, C., Tee, J.Y.,

Leyton, L., Murrell, W., Cooper-White, J., McGrath, J.J. and Mackay-Sim, Alan* (*Griffith University, QLD)

11:45 ORAL-11-06 Plasticity induced in the prefrontal cortex is impaired in

people with schizophrenia Rogasch, Nigel*, Rajji, T.K., Tran, L.C., Fitzgerald, P.B. and

Daskalakis, Z.J. (*Monash University, VIC) 12:00 ORAL-11-07 An analysis of metabotropic glutamate receptors 2/3 and 5 in

schizophrenia, major depression and bipolar disorder from the Stanley Neuropathology Consortium

Matosin, Natalie*, Frank, E., Fernandez, F., Deng, C., Wong, J., Huang, X.F. and Newell, K.A. (*University of Wollongong, NSW)

12:15 ORAL-11-08 Expression of proteins within the Nogo receptor complex are

altered in the dorsolateral prefrontal cortex in schizophrenia Andrews, Jessica*, Newell, K. and Fernandez, F.



10:30 – 12:30 ORAL 12

SYNAPTIC TRANSMISSION AND EXCITABILITY II Chair: Dr Nigel Jones, University of Melbourne, VIC Location: Meeting Room 104 10:30 ORAL-12-01 tDCS applied to the forearm region of M1 modulates cortical

excitability and intracortical inhibition Zhang, Xue*, Van Den Berg, F.E., Swinnen, S.P., Feys, H.

and Wenderoth, N. (*Research Centre for Movement Control Neuroplasticity, Belgium)

10:45 ORAL-12-02 Changes in synaptic inputs to retinal ganglion cells during

retinal degeneration Saha, Susmita*, Greferath, U., Nowell, C., Grayden, D.,

Burkitt, A. and Fletcher, E. (*University of Melbourne, VIC) 11:00 ORAL-12-03 GSK3 mediated phosphorylation of PI4K2A regulates vesicle

trafficking: implications for mood disorders Robinson, James*, Farghaian, H., Hughes, W.E., Wang, Q.,

Neely, G.G. and Cole, A.R. (*Garvan Institute for Medical Research, NSW)

11:15 ORAL-12-04 Acto-myosin II constricting rings contributes to activity

dependent bulk endocytosis in chromaffin cells Gormal, Rachel*, Nguyen, T.H. Wen, P.J. and Meunier, F.A.

(*University of Queensland, QLD)


11:30 ORAL-12-05 PICK1 interacts with PACSINI1 to regulate AMPA receptor

trafficking Anggono, Victor*, Widagdo, J., Quan, A., Wegener, E., Koc-

Schmitz, Y., Schael, S., Chen, C.M., Robinson, P.J., Plomann, M. and Huganir, R.L. (*University of Queensland, QLD)

11:45 ORAL-12-06 Isolating the bulk endosome from nerve terminals Miller, Linda*, Hains, P., Kettle, E., Boadle, R.A. and

Robinson, P.J. (*Children's Medical Research Institute, NSW) 12:00 ORAL-12-07 Electrophysiological and molecular development of substantia

nigra pars compacta dopaminergic neurons Dufour, M., Woodhouse, Adele*, Amendola, J. and

Goaillard, J.-M. (*University of Tasmania, TAS) 12:15 ORAL-12-08 Huntingtin-associated protein 1 (HAP1) regulates exocytosis,

vesicle localisation and interacts with multiple vesicle proteins Mackenzie, K.D., Zhou, X.F. and Keating, Damien*

(*Flinders University of South Australia, SA)


10:30 – 12:30 ORAL 13

SENSORY SYSTEMS II: VISION Chair: Professor Shaun Collin, University of Western Australia,

WA Location: Meeting Rooms 101/102 10:30 ORAL-13-01 The role of Cx3cr1 signalling in regulating photoreceptor

integrity Fletcher, Erica*, Vessey, K.A., Waugh, M. and Jobling, A.I.

(*University of Melbourne, VIC) 10:45 ORAL-13-02 Cone bipolar types in primate retina: quantitative analysis Percival, Kumiko*, Martin, P.R. and Grunert, U. (*Save

Sight Institute, NSW) 11:00 ORAL-13-03 Plasticity of the primate retinothalamo-MT pathways

following lesions of the striate cortex (V1) during development and adulthood

Bourne, James*, Johnston, L., Egan G.F. and Warner, C.E. (*Australian Regenerative Medicine Institute, VIC)

11:15 ORAL-13-04 Timescales of long-range response correlations in visual areas

V2 and DM Price, Nic*, Haghgooie, S., Yu, H.-H., Davies, A.J. and Rosa,

M.G.P. (*Monash University, VIC)


11:30 ORAL-13-05 Saccade direction modulates post-saccadic enhancement of

ocular following eye speed Cloherty, Shaun* Hietanen, M.A., Price, N.S.C., Rosa, M.G.

and Ibbotson, M.R. (*National Vision Research Institute, VIC)

11:45 ORAL-13-06 The role of protein arginine methyltransferase 8 in visual

cortical critical period Lee, P.K.M. and Sng, Judy* (*Agency for Science and

Technology, Singapore) 12:00 ORAL-13-07 Correlations and synchrony in the middle temporal area

depend on functional distance and tuning Solomon, Selina*, Chen, S.C., Morley, J.W. and Solomon,

S.G. (*University of Sydney, NSW) 12:15 ORAL-13-08 Comparison of fluorescein angiography dynamics between the

eye and brain Hui, Flora*, Nguyen, C.T., He, Z., Fish, R.L., Gurrell, R.,

Vingrys, A.J. and Bui, B.V. (*University of Melbourne, VIC)

12:30 – 13:00 LUNCH/EXHIBITION (Lunch provided) Location: Main Foyer

13:00– 15:00 POSTER SESSION B / EXHIBITION 13:00 – 14:00 Presenters of odd numbered posters in attendance 14:00 – 15:00 Presenters of even numbered posters in attendance Location: Main Foyer

15:00 – 15:40 AFTERNOON TEA / EXHIBITION / POSTERS (Including Passport Draw)

Location: Main Foyer


15:40 – 16:55

ANS ANNUAL GENERAL MEETING


17:00 – 18:00

PLENARY 4

ANS PLENARY LECTURE

Chair: Professor Sarah Dunlop, University of Western Australia, WA


PLE-TUE-04 Food on the brain Morris, Margaret (University of New South Wales, NSW)

Professor Margaret Morris

Margaret Morris is chair and Head of Pharmacology, School of Medical Sciences, UNSW. She completed her PhD at Monash University in 1983. After postdoctoral work in Adelaide and Paris she took an academic appointment at Deakin. In 1995 she moved to University of Melbourne, where she began exploring the brain mechanisms involved in food intake and metabolism using animal models of obesity

and diabetes. In 2005 she joined UNSW where she teaches in Medicine, Optometry, Medical Science and Science. An author of 160 papers and reviews, her current research addresses critical questions concerning the impact of adverse early life events and lifestyle factors on chronic disease risk. Using neuropharmacological approaches, she explores underlying CNS mechanisms in epilepsy, obesity, diabetes, and the link between obesity and hypertension. Research in the Morris lab showed a palatable high fat diet can ameliorate the behavioral effects of early life stress. Current NHMRC funded work includes intergenerational transmission of obesity and the psychology of eating, e.g. how does provision of a varied, energy rich diet override the regulatory control mechanisms should maintain body weight?

19:30 – 23:30 CONFERENCE DINNER Location: Melbourne Town Hall

WEDNESDAY 6 FEBRUARY 2013

09:00 – 11:00 SYMPOSIUM 12

ANS PRESIDENTIAL SYMPOSIUM: Early intervention in psychosis: what happens in the brain

before, during and after the development of psychosis and can we stop it?

Chair: A/Prof Maarten van den Buuse, Florey Institute of

Neuroscience & Mental Health, VIC Location: Meeting Room 105 09:00 SYM-12-01 The developing brain: pathways through adolescence Lenroot, Rhoshei (University of New South Wales, NSW) 09:30 SYM-12-02 Drugs, stress and inflammation: explaining progressive brain

changes in schizophrenia Pantelis, Christos (University of Melbourne, VIC) 10:00 SYM-12-03 Early intervention in psychosis: what can be learned from

animal models Weiner, Ina* and Pointkewitz, Y. (*Tel Aviv University,

Israel) 10:30 SYM-12-04 Indicated prevention in patients in incipient risk of developing

psychosis McGorry, Patrick (University of Melbourne, VIC)


09:00 – 11:00 SYMPOSIUM 13

NEURAL PLASTICITY AND THE GUT Chairs: Professor Simon Brookes, Flinders University of South

Australia, SA A/Prof Nicholas Spencer, Flinders University of South

Australia, SA Location: Meeting Room 106 09:00 SYM-13-01 Serotonergic regulation of enteric nervous system

development/plasticity Gershon, Michael (Columbia University, USA) 09:30 SYM-13-02 Mechanisms underlying neuronal cell death in colitis Sharkey, Keith (University of Calgary, Canada)

10:00 SYM-13-03 Role of TRP channels in the mechanical hypersensitivity of

extrinsic sensory neurons that project to the gut Brierley, Stuart (University of Adelaide, SA) 10:30 SYM-13-04 Enteric nervous system as a therapeutic target Nurgali, Kulmira (Victoria University, VIC)


09:00 – 11:00 SYMPOSIUM 14

THE NEURONAL CYTOSKELETON IN HEALTH AND DISEASE

Chair: A/Prof Fred Meunier, Queensland Brain Institute, QLD Location: Meeting Rooms 101/102 09:00 SYM-14-01 Physiology and dynamics of the microtubule-associated

protein tau during neuronal development and maintenance Brandt, Roland (University of Osnabrueck, Germany) 09:30 SYM-14-02 GSK3 regulates vesicular trafficking via the lipid kinase

Pl4K2A: implications for mood disorders Cole, Adam (Garvan Institute, NSW) 10:00 SYM-14-03 Axon degeneration in trauma and disease: a critical role for

the neurofilaments Dickson, Tracey (Menzies Research Institute, TAS) 10:30 SYM-14-04 Tropomyosins are key regulators of different actin filament

populations that control neuronal morphogenesis and function Curthoys, N.M., Freittag, H. and Fath, Thomas* (*University

of New South Wales, NSW)


09:00 – 11:00 ORAL 14

DISORDERS AND INJURY OF THE NERVOUS SYSTEM IV Chair: A/Prof Ann Turnley, University of Melbourne, VIC Location: Meeting Room 103 09:00 ORAL-14-01 Expression of the neurite outgrowth inhibitor NogoA

following focal ischemia of primate neocortex is greater in the neonate compared to the adult

Boghdadi, Anthony*, Teo, L., Krishnamurthy, G. and Bourne, J.A. (*Australian Regenerative Medicine Institute, VIC)

09:15 ORAL-14-02 The role of the cytoskeleton and caspase activation in

axonopathy following excitotoxicity in vitro King, Anna*, Southam, K.A., Dickson, T.C. and Vickers,

J.C. (*University of Tasmania, TAS) 09:30 ORAL-14-03 The potential of NK1 antagonists as anti-cancer agents in

brain tumours Harford-Wright, Elizabeth*, Lewis, K.M., Vink, R. and

Ghabriel, M.N. (*University of Adelaide, SA) 09:45 ORAL-14-04 Role of chemokine signaling in an animal model of atrophic

age-related macular degeneration Rutar, Matt*, Chia, R.X., Natoli, R. and Provis, J.M. (*John

Curtin School of Medical Research, ACT)


10:00 ORAL-14-05 In vivo sutureless median nerve repair Barton, Matthew*, Mahns, D.A., Morley, J.W., Stoodley,

M., Piller, S.C. and Lauto, A. (*University of Western Sydney, NSW)

10:15 ORAL-14-06 Variability in α- and β-synuclein in Parkinson's disease and

multiple system atrophy Stevens, Claire*, Lewis, S. and Halliday, G.M.

(*Neuroscience Research Australia, NSW) 10:30 ORAL-14-07 Cortical pyramidal neurons demonstrate resilience to

degeneration following mild traumatic brain injury in the adult mouse

Chuckowree, Jyoti* and Dickson, T.C. (*Menzies Research Institute, TAS)

10:45 ORAL-14-08 A rare functional haplotype of the P2RX4 and P2RX7 genes

leads to loss of innate phagocytosis and confers increased risk of age related macular degeneration

Gu, Ben*, Baird, P.N., Vessey, K.A., Skarratt, K.K., Fletcher, E.L., Fuller, S.J., Richardson, A.J., Guymer, R.H. and Wiley, J.S. (*Florey Institute of Neuroscience and Mental Health, VIC)


09:00 – 11:00 ORAL 15

COGNITION, LEARNING AND BEHAVIOUR II Chair: Dr Nic Price, Monash University, VIC Location: Meeting Room 104 09:00 ORAL-15-01 Motions add, orientations don't, in the human visual system Freeman, Alan (University of Sydney, NSW) 09:15 ORAL-15-02 Combination of antipsychotics with a positive allosteric

modulator of the M1 muscarinic receptor yields synergistic efficacy in animal models of schizophrenia

Choy, Christopher*, Lane, J.R., Langmead, C., Malone, D.T., Sexton, P.M. and Christopoulos, A. (*Monash Institutre of Pharamceutical Sciences, VIC)

09:30 ORAL-15-03 Response sensitivity in the auditory brainstem altered by fear

conditioned frequency discrimination Paolini, Tony* and Morgan, S. (*RMIT University, VIC) 09:45 ORAL-15-04 Development of a cellular-resolution connectivity atlas of the

primate cerebral cortex Chaplin, T.A., Yu, H.H., Pinskiy, V., Tolpygo, A., Mukherjee,

A., Mitra, P.P. and Rosa, Marcello* (*Monash University, VIC)

10:00 ORAL-15-05 Genetic analysis of HDAC4 function in long-term memory Fitzsimons, Helen* and Scott, M.J. (*Massey University,

New Zealand)


10:15 ORAL-15-06 Novel method for determining frequency discrimination

abilities of cats without using negative reinforcement Benovitski, Yuri*, Fallon, J.B., Blamey, P.J. and Rathbone,

G.D. (*Bionics Institute, VIC) 10:30 ORAL-15-07 How many scenes are seen? Attention allocation in multiplex

displays Stainer, Matt*, Tatler, B.W. and Scott-Brown, K.C.

(*University of Dundee, UK) 10:45 ORAL-15-08 Neural encoding of competitive effort in the anterior cingulate

cortex Hillman, Kristin* and Bilkey, D.K. (*University of Otago,

New Zealand)

11:00 – 11:30 MORNING TEA Location: Main Foyer

WEDNESDAY 6 FEBRUARY 2013 11:30 – 13:30 SYMPOSIUM 15

ONE GENE CLOSER – UNDERSTANDING THE NEUROBIOLOGY OF INTELLECTUAL DISABILITY

Chairs: Dr Matilda Haas, Australian Regenerative Medicine

Institute, VIC Dr Michael Piper, University of Queensland, QLD Location: Meeting Rooms 101/102 11:30 SYM-15-01 Neurobiology of X-chromosome linked intellectual disability,

extreme genetic heterogeneity, unexpected mutation pleiotropy and sex (male and female) bias

Gecz, Jozef (SA Pathology/ University of Adelaide, SA) 12:00 SYM-15-02 Fgf8 signalling regulates telencephalic midline development

and formation of the corpus callosum Gobius, Ilan* and Richards, L.J. (*Queensland Brain

Institute, QLD) 12:30 SYM-15-03 The tubulin gene family and neurodevelopmental disease Keays, David (Institute for Molecular Pathology, Austria) 13:00 SYM-15-04 A novel basis for the development of intellectual disability in

Down syndrome Heng, Julian (Australian Regenerative Medicine Institute,

VIC)


11:30 – 13:30 SYMPOSIUM 16

STRESS AND THE BRAIN: COMPARATIVE APPROACHES TO UNDERSTANDING PLASTICITY

Chair: Professor Trevor Day, Deakin University, VIC Location: Meeting Room 106 11:30 SYM-16-01 Modulating effect of 'calming' odours on stress, aggressive

behaviour and gene expression in insect brains Reinhard, Judith*, Van Der Burg, N., Lavidis, N. and

Claudianos, C. (*Queensland Brain Institute, QLD) 12:00 SYM-16-02 Stress and vocal learning in songbirds: the effects of genotype

and environment Buchanan, Kate*, Leitner, S., Catchpole, C.K., Woodgate,

J.W. and Bennett, A.T.D. (*Deakin University, VIC) 12:30 SYM-16-03 The role of microglia in cognitive disturbance: a new frontier

in the neurobiology of stress Walker, Rohan (University of Newcastle, NSW) 13:00 SYM-16-04 The effects of stress on the morphology and function of the

avian songbird brain Gahr, Manfred* and Leitner, S. (*Max Planck Institute for

Ornithology, Germany)


11:30 – 13:30 SYMPOSIUM 17

PERINATAL BRAIN INJURY: CAUSE AND CURE Chair: Dr Mary Tolcos, Monash Institute of Medical Research,

VIC Location: Meeting Room 105 11:30 SYM-17-01 Brain injury in the preterm infant: can we improve outcomes? Juul, S.J. (University of Washington, USA) 12:00 SYM-17-02 GABA, HI injury and seizures in the newborn brain Bjorkman, Tracey (University of Queensland, QLD) 12:30 SYM-17-03 Antenatal glucocorticoids, what we know and what we should

know Bennet, Laura*, Koome, M. and Gunn, A.J. (*University of

Auckland, New Zealand) 13:00 SYM-17-04 Protecting the newborn brain with melatonin Miller, Suzie*, Yawno, T., Aridas, J.D., Fahey, M., Jenkin,

G. and Wallace, E.M. (*Monash University, VIC)


11:30 – 13:30 ORAL 16

GLIA Chair: Dr Toby Merson, Florey Institute of Neuroscience &

Mental Health, VIC Location: Meeting Room 103 11:30 ORAL-16-01 Lead (Pb) modulates human microglia inflammatory

responses Etemad, Samar*, Ruitenberg, M. and Filgueira, L.

(*University of Western Australia, WA) 11:45 ORAL-16-02 Regulation of zinc transporters in neurons and astrocytes Hancock, Sara*, Finkelstein, D.I., Bush, A.I. and Adlard,

P.A. (*Mental Health Research Institute, VIC) 12:00 ORAL-16-03 Astrocytes maintained on 3D nanoscaffolds exhibit altered

phenotypic responses to Rho kinase inhibitors Zulaziz, Natasha*, Lau, C.L. Nisbet, D.R., Horne, M.K.,

Beart, P.M. and O'Shea, R.D. (*La Trobe University, VIC) 12:15 ORAL-16-04 Astrocytes in TDP-43 pathology Chen, T. and Muyderman, Hakan* (*Flinders University of

South Australia, SA) 12:30 ORAL-16-05 The role of BDNF in CNS myelination and remyelination Wong, Agnes*, Xiao, J., Sabo, J., Kemper, D., Cate, H.,

Kilpatrick, T.J. and Murray, S.S. (*University of Melbourne, VIC)


12:45 ORAL-16-06 Transcriptional control of myelin maintenance in the adult

CNS Koenning, Matthias*, Jackson, S., Hay, C.M., Willingham,

M. and Emery, B. (*University of Melbourne, VIC) 13:00 ORAL-16-07 Oligodendrocyte dynamics in the healthy adult CNS:

evidence for myelin remodeling Young, Kaylene*, Psachoulia, K., Tripathi, R.B., Dunn, S.,

Attwell, D., Tohyama, K. and Richardson, W.D. (*Menzies Research Institute, TAS)

13:15 ORAL-16-08 Peri-infarct glial cell responses in a photothrombotic model of

stroke in rats Yew, Wai Ping*, Djukic N.D., Jayaseelan, J.S.P.,

Muyderman, H. and Sims, N.R. (*Flinders University of South Australia, SA)


11:30 – 13:30 ORAL 17

NEW TECHNIQUES IN NEUROSCIENCE Chair: A/Prof Jenny Rodger, University of Western Australia,

WA Location: Meeting Room 104 11:30 ORAL-17-01 Efficient delivery of siRNAs to neurons using layered double

hydroxide nanoparticles Chen, M., Xu, Z.P., Bartlett, P.F., Lu, G.Q. and Cooper,

Helen* (*University of Queensland, QLD) 11:45 ORAL-17-02 Conscious, simultaneous recordings of rodent visual

electrophysiology: improved clinical translatability Charng, Jason*, He, Z., Vingrys, A.J., Bui, B.V., Fish, R.L.,

Gurrell, R. and Nguyen, C.T. (*University of Melbourne, VIC)

12:00 ORAL-17-03 Deep brain stimulation and cortical activation Jonmohamadi, Yaqub*, Weiss, D.W., Krueger, R.K., Innes,

C.I. and Jones, R.D. (*University of Otago, New Zealand) 12:15 ORAL-17-04 A physiologically plausible spatiotemporal model of bold

allows deconvolution of hemodynamic and neuron response components

Aquino, Kevin*, Schira, M.M., Robinson, P.A. and Breakspear, M. (*University of Sydney, NSW)


12:30 ORAL-17-05 Defining mechanical states of peristalsis using combined

impedance/manometry intraluminal recording Dinning, Phil*, Omari, T., Wiklendt, L., Spencer, N.J. and

Costa, M. (*Flinders University of South Australia, SA) 12:45 ORAL-17-06 Development of viral vector-mediated pharmacogenetic tools

to facilitate in vivo investigation of nucleus incertus / relaxin-3 neural networks

Hawkes, David*, Ong-Pålsson, E.K.E., Smith, C.M., Ma, S., White, M.D., Bathgate, R.A.D. and Gundlach, A.L.

(*Florey Institute of Neuroscience & Mental Health, VIC) 13:00 ORAL-17-07 Towards development of AAV vectors for treatment of

leukodystrophies von Jonquieres, Georg*, Klugmann, C., Harasta, A. and

Klugmann, M. (*University of New South Wales, NSW) 13:15 ORAL-17-08 Measuring the spatiotemporal profiles of neuronal activity and

BOLD in early visual cortex using high resolution fMRI Schira, Mark*, Breakspear, M. and Aquino, K.M.


13:30 – 14:30 LUNCH BREAK (lunch may be purchased at nearby cafés)


14:30 – 16:30 SYMPOSIUM 18

NEURO-IMMUNE CROSSTALK IN NERVOUS SYSTEM DISORDERS

Chair: Professor Gilles Guillemin, Macquarie University, NSW Location: Meeting Room 105 14:30 SYM-18-01 Involvement of immune responses in peripheral neuropathies Moalem-Taylor, Gila (University of New South Wales,

NSW) 15:00 SYM-18-02 The toll of central immune signalling: implications for pain

and its treatment Hutchinson, Mark (University of Adelaide, SA) 15:30 SYM-18-03 Roles of professional and non-professional phagocytes in

brain maintenance Derecki, Noel*, Cronk, J.C., Lu, Z. and Kipnis, J.

(*University of Virginia, USA) 16:00 SYM-18-04 Immune reactivity and influence upon neuronal pathology

following oligodendrocyte apoptosis Merson, T.D., Xing, Y.L., Stratton, J.S., Wikhe, K., Ng, S.W.

and Kilpatrick, Trevor* (*University of Melbourne, VIC)


14:30 – 16:30 SYMPOSIUM 19

PTEN IN THE BRAIN Chair: Dr Jason Howitt, Florey Institute of Neuroscience &

Mental Health, VIC Location: Meeting Room 106 14:30 SYM-19-01 Regulation of the actin binding protein Drebrin by the PTEN

tumour suppressor at the CNS synapse Kreis, P., Kay, L., Hendricusdottir, R., van Diepen, M.,

Burrone, J., Parsons, M. and Eickholt, Britta* (*Universitätsmedizin Berlin, Germany)

15:00 SYM-19-02 How PTEN keeps neurons alive after injury Tan, Seong-Seng (Florey Institute of Neuroscience and

Mental Health, VIC) 15:30 SYM-19-03 Long antisense non-coding RNAs; epigenetic regulators of

gene transcription in human cells Morris, Kevin (University of New South Wales, NSW) 16:00 SYM-19-04 Role of inositol polyphosphate 5-phosphatases in neuronal

function Dyson, J., Conduit, S., Hakim, S., Smyth, I. and Mitchell,

Christina* (*Monash University, VIC)


14:30 – 16:30 ORAL 18

DISORDERS AND INJURY OF THE NERVOUS SYSTEM V: MOVEMENT DISORDERS

Chair: A/Prof Kay Double, University of Sydney, NSW Location: Meeting Rooms 101/102 14:30 ORAL-18-01 Analysis of planning and online control of movement in

multiple sclerosis using a Fitts' law reciprocal aiming paradigm

Ternes, Anne-Marie*, Fielding, J., Corben, L., White, O., Bradshaw, J.L., Hocking, D. and Georgiou-Karistianis, N. (*Monash University, VIC)

14:45 ORAL-18-02 p75NTR may be a biomarker for motor neuron disease

progression Shepheard, Stephanie*, Chataway, T., Schultz, D., Smith,

K.S., Rush, R.A. and Rogers, M.-L. (*Flinders University of South Australia, SA)

15:00 ORAL-18-03 Chronically elevated stress hormone accelerates the onset of

memory decline in Huntington's disease mice Mo, Christina*, Renoir, T. and Hannan, A.J. (*Florey

Institute of Neuroscience and Mental Health, VIC) 15:15 ORAL-18-04 Global fatty acid composition is altered in Parkinson's disease

anterior cingulate cortex Abbott, Sarah*, Halliday, G.M. and Garner, B. (*University

of Wollongong, NSW)


15:30 ORAL-18-05 Reduced copper, copper transport proteins and cuproprotein

SOD1 activity in the substantia nigra in Parkinson's disease Davies, Katherine*, Bohic, S., Ortega, R., Cottam, V., Hare,

D.J., Finberg, J.P.M., Halliday, G., Mercer, J.F.B. and Double, K.L. (*Neuroscience Research Australia, NSW)

15:45 ORAL-18-06 Identification and characterisation of a novel gene associated

with X-linked early onset Parkinsonism Wilson, G.R., Fitzpatrick, E., McLean, C., Gregg, R.C.,

Bromhead, C., Lawrence, C., Bahlo, M., Leventer, R., Delatycki, M., Amor, D. and Lockhart, Paul* (*Murdoch Childrens Research Institute, VIC)

16:00 ORAL-18-07 Acute effects of rotenone on Locus Coeruleus and Substantia

Nigra pars compacta neurons: implications for Parkinson's disease

Yee, Andrew*, Freestone, P.S. and Lipski, J. (*University of Auckland, New Zealand)

16:15 ORAL-18-08 MAPT genotype, methylation and their implications for late-

onset Parkinson's disease Coupland, Kirsten*, Dobson-Stone, C., Mellick, G., Kim,

W., Halliday, G. and Kwok, J. (*Neuroscience Research Australia, NSW)


14:30 – 16:30 ORAL 19

DEVELOPMENT AND REGENERATION II Chair: A/Prof Helen Cooper, Queensland Brain Institute, QLD Location: Meeting Room 103 14:30 ORAL-19-01 Enteric gangliogenesis driven by differential cell adhesion:

cell biological and mathematical models Newgreen, Donald*, Hackett-Jones, E.J., Landman, K.A.,

Zhang, D.C. and Binder, B. (*Murdoch Children's Research Institute, VIC)

14:45 ORAL-19-02 A pathogenetic model for Tourette syndrome Eapen, Valsa* and Clarke, R. (*University of New South

Wales, NSW) 15:00 ORAL-19-03 Sex specific effects of prenatal stress on myelination in the

hippocampus, cerebral cortex and cerebellum Bennett, Greer*, Palliser, H.K. and Hirst, J.J. (*University of

Newcastle, NSW) 15:15 ORAL-19-04 Embryonic development and maturation of cholinergic enteric

neurons Hao, M.M., Young, H.M. and Bornstein, Joel* (*University

of Melbourne, VIC) 15:30 ORAL-19-05 Striatal projection neurons are generated through a latent

period of neurogenesis in the neonatal rodent brain Wright, Jordan*, Stanic, D. and Thompson, L.H.

(*University of Melbourne, VIC)


15:45 ORAL-19-06 Regeneration and protection in the deaf cochlea Atkinson, Patrick*, Wise, A.K., Flynn, B.O., Nayagam,

B.A., Hume, C.R., O'Leary, S.J., Shepherd, R.K. and Richardson, R.T. (*Bionics Institute, VIC)

16:00 ORAL-19-07 Using zebrafish to identify factors involved in neurogenesis

and brain regeneration Colquhoun, D., Tang, K. and Kaslin, Jan* (*Australian

Regenerative Medicine Institute, VIC) 16:15 ORAL-19-08 Establishment of the olfactory bulb in embryonic mice Amaya, Daniel*, Ekberg, J. and St John, J. (*Griffith

University, QLD)


14:30 – 16:30 ORAL 20

SENSORY SYSTEMS III: SOMATOSENSORY Chair: Dr James Fallon, Bionics Institute, VIC Location: Meeting Room 104 14:30 ORAL-20-01 Modulating effect of oral sucrose on β endorphin and pain

perception Suri, Manjula*, Jain, S. and Mathur, R. (*University of

Delhi, India) 14:45 ORAL-20-02 Encoding of object softness by tactile mechanoreceptors in the

human finger pads Condon, M., Hudson, K., Chelvanayagam, D., Mahns, D.,

Birznieks, I., Olausson, H., Lamotte, R.H. and Macefield, Vaughan* (* University of Western Sydney, NSW)

15:00 ORAL-20-03 Gain modulation of neuronal responsiveness by persistently

active state in neocortex Yang, Xiufeng*, Yang, M. and Shu, Y. (*Chinese Academy

of Sciences, China) 15:15 ORAL-20-04 Barrelettes, barreloids and barrels: structures and connectivity

of the somatosensory pathway revealed using super resolution tractography

Richards, Kay*, Calamante, F., Tournier, J.-D., Kurniawan, N.D., Reutens, D.C., Reid, C.A., Connelly, A. and Petrou, S. (*Florey Institute of Neuroscience and Mental Health, VIC)


15:30 ORAL-20-05 Increased efficacy of the peripherally-restricted kappa-opioid

receptor agonist, Asimadoline, in chronic visceral hypersensitivity

Hughes, P.A., Harrington, A.M., Castro, J., Isaacs, N., Moretta, M., Hicks, G.A., Urso, D.M. and Brierley, Stuart* (*University of Adelaide, SA)

15:45 ORAL-20-06 Whisker-mediated vibration detection: neural coding and

behaviour Lee, Conrad*, McDonald, J.S. and Arabzadeh, E.

(*University of New South Wales, NSW) 16:00 ORAL-20-07 Ampullary structure and electrosensory hyperacuity in sharks Pullar, Kiri* and Paulin, MG. (*University of Otago, New

Zealand) 16:15 ORAL-20-08 The effect of placebo conditioning on regional brain blood

oxygen level-dependent signal changes during capsaicin-evoked urge-to-cough

Leech, Jennifer*, Farrell, M.J. and Mazzone, S.B. (*Florey Institute of Neuroscience and Mental Health, VIC)

16:45 FAREWELL DRINKS & PRESENTATION OF AWARDS Location: Level 1 Foyer

sunday 3 february 2013 2013 - final p… · sunday 3 february 2013 13:00 – 15:00 . australian...

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