supplemental digital content -...

25
1 Drug Safety Preventability of Drug-Related Harms – Part I A Systematic Review Ferner RE, Aronson JK Supplemental Digital Content This Supplemental Digital Content contains the appendix referred to in the full version of this article, which can be found at http://adisonline.com/drugsafety © 2010 Adis Data Information BV. All rights reserved.

Upload: dinhdien

Post on 16-Aug-2019

213 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

1

Drug Safety Preventability of Drug-Related Harms – Part I

A Systematic Review

Ferner RE, Aronson JK

Supplemental Digital Content This Supplemental Digital Content contains the appendix referred to in the full version of this article, which can be found at http://adisonline.com/drugsafety

© 2010 Adis Data Information BV. All rights reserved.

Page 2: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

2

Appendix

1. Ackroyd-Stolarz S, Hartnell N, MacKinnon NJ. Demystifying medication safety:

making sense of the terminology. Res Social Adm Pharm 2006; 2(2): 280-9.

2. Alexopoulou A, Dourakis SP, Mantzoukis D, Pitsariotis T, Kandyli A, Deutsch M,

Archimandritis AJ. Adverse drug reactions as a cause of hospital admissions: a 6-

month experience in a single center in Greece. Eur J Intern Med 2008; 19(7): 505-

10.

3. Allen JE. Risk factors and prevention strategies for adverse drug reactions. J Pharm

Care Pain Symptom Control 1995; 3(1): 31-5.

4. Al-Malaq HM, Al-Aqeel SA, Al-Sultan MS. Adverse drug reactions related

hospitalization identified by discharge ICD-9 codes in a university hospital in

Riyadh. Saudi Med J 2008; 29(8): 1145-50.

5. Baena MI, Faus MJ, Fajardo PC, Luque FM, Sierra F, Martinez-Olmos J, Cabrera

A, Fernandez-Llimos F, Martinez-Martinez F, Jimenez J, Zarzuelo A. Medicine-

related problems resulting in emergency department visits. Eur J Clin Pharmacol

2006; 62(5): 387-93.

6. Bailey TC, Noirot LA, Christensen EM, Milligan PE, Kimmel NL, Fraser VJ,

Dunagan WC. Validation of automated event triggers using laboratory values

related to two problem-prone drugs. AMIA Annu Symp Proc 2003: 781.

7. Baker GR, Norton PG, Flintoft V, Blais R, Brown A, Cox J, Etchells E, Ghali WA,

Hébert P, Majumdar SR, O'Beirne M, Palacios-Derflingher L, Reid RJ, Sheps S,

Page 3: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

3

Tamblyn R. The Canadian Adverse Events Study: the incidence of adverse events

among hospital patients in Canada. CMAJ 2004; 170(11): 1678-86.

8. Bartlett G, Blais R, Tamblyn R, Clermont RJ, MacGibbon B. Impact of patient

communication problems on the risk of preventable adverse events in acute care

settings. CMAJ 2008; 178(12): 1555-62.

9. Bates DW, Boyle DL, Vander Vliet MB, Schneider J, Leape L. Relationship

between medication errors and adverse drug events. J Gen Intern Med 1995; 10(4):

199-205.

10. Bates DW, Cullen DJ, Laird N, Petersen LA, Small SD, Servi D, Laffel G, Sweitzer

BJ, Shea BF, Hallisey R, Vander Vliet M, Nemeskal R, Leape LL. Incidence of

adverse drug events and potential adverse drug events. Implications for prevention.

ADE Prevention Study Group. JAMA 1995; 274(1): 29-34.

11. Bates DW, Leape LL, Cullen DJ, Laird N, Petersen LA, Teich JM, Burdick E,

Hickey M, Kleefield S, Shea B, Vander Vliet M, Seger DL. Effect of computerized

physician order entry and a team intervention on prevention of serious medication

errors. JAMA 1998; 280(15): 1311-6.

12. Bates DW, Leape LL, Petrycki S. Incidence and preventability of adverse drug

events in hospitalized adults. J Gen Intern Med 1993; 8(6): 289-94.

13. Bates DW, O'Neil AC, Boyle D, Teich J, Chertow GM, Komaroff AL, Brennan

TA. Potential identifiability and preventability of adverse events using information

systems. J Am Med Inform Assoc 1994; 1(5): 404-11.

Page 4: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

4

14. Bates DW, Teich JM, Lee J, Seger D, Kuperman GJ, Ma'Luf N, Boyle D, Leape L.

The impact of computerized physician order entry on medication error prevention. J

Am Med Inform Assoc 1999; 6(4): 313-21.

15. Bates DW. Medication errors. How common are they and what can be done to

prevent them? Drug Saf 1996; 15(5): 303-10.

16. Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC. Explicit

criteria for determining inappropriate medication use in nursing home residents.

UCLA Division of Geriatric Medicine. Arch Intern Med 1991; 151(9): 1825-32.

17. Beers MH. Explicit criteria for determining potentially inappropriate medication

use by the elderly. An update. Arch Intern Med 1997; 157(14): 1531-6.

18. Beijer HJ, de Blaey CJ Hospitalisations caused by adverse drug reactions (ADR): a

meta-analysis of observational studies. Pharm World Sci 2002; 24(2): 46-54.

19. Bigby J, Dunn J, Goldman L, Adams B, Jen P, Landefeld GS, Komaroff AL.

Assessing the preventability of emergency hospital admissions. Am J Med 1987; 3:

1031-6.

20. Bobb A, Gleason K, Husch M, Feinglass J, Yarnold PR, Noskin GA. The

epidemiology of prescribing errors: the potential impact of computerized prescriber

order entry. Arch Intern Med 2004; 164(7): 785-92.

21. Brennan TA, Hebert LE, Laird NM, Lawthers A, Thorpe KE, Leape LL, Localio

AR, Lipsitz SR, Newhouse JP, Weiler PC, Hiatt HH. Hospital characteristics

associated with adverse events and substandard care. JAMA 1991; 265(24): 3265-

9.

Page 5: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

5

22. Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG,

Newhouse JP, Weiler PC, Hiatt HH. Incidence of adverse events and negligence in

hospitalized patients. Results of the Harvard Medical Practice Study I. N Engl J

Med 1991; 324(6): 370-6.

23. Buckley MS, Erstad BL, Kopp BJ, Theodorou AA, Priestley G. Direct observation

approach for detecting medication errors and adverse drug events in a pediatric

intensive care unit. Pediatr Crit Care Med 2007; 8(2): 145-52.

24. Budnitz DS, Shehab N, Kegler SR, Richards CL. Medication use leading to

emergency department visits for adverse drug events in older adults. Ann Intern

Med 2007; 147(11): 755-65.

25. Burkhardt H. Wehling M. Gladisch R. Prävention unerwunschter

Arzneimittelwirkungen bei alteren Patienten. [Prevention of adverse drug reactions

in older patients.] Zeitschrift fur Gerontologie und Geriatrie 2007; 40(4): 241-54.

26. Burnum JF. Preventability of adverse drug reactions. Ann Intern Med 1976; 85(1):

80-1.

27. Calderon-Ospina C, Orozco-Diaz J. Reacciones adversas a medicamentos como

motivo de consulta en un servicio de atencion prioritaria. [Adverse drug reactions

as the reason for visiting an emergency department.] Rev Salud Publica (Bogota)

2008; 10(2): 315-21.

28. Chan M, Nicklason F, Vial JH. Adverse drug events as a cause of hospital

admission in the elderly. Intern Med J 2001; 31(4): 199-205.

Page 6: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

6

29. Cimino MA, Kirschbaum MS, Brodsky L, Shaha SH; Child Health Accountability

Initiative. Assessing medication prescribing errors in pediatric intensive care units.

Pediatr Crit Care Med 2004; 5(2): 124-32.

30. Committee on Drugs and Committee on Hospital Care. Prevention of medication

errors in the pediatric inpatient setting. American Academy of Pediatrics.

Committee on Drugs and Committee on Hospital Care. Pediatrics 1998; 102(2 Pt

1): 428-30.

31. Cooper JB, Newbower RS, Long CD, McPeek B. Preventable anesthesia mishaps: a

study of human factors. Qual Saf Health Care 2002 Sep; 11(3): 277-82. Reprinted

from Anesthesiology 1978; 49: 399-406.

32. Cousins DD. Developing a uniform reporting system for preventable adverse drug

events. Clin Ther 1998; 20 Suppl C: C45-58.

33. Cresswell KM, Fernando B, McKinstry B, Sheikh A. Adverse drug events in the

elderly. Br Med Bull 2007; 83: 259-74.

34. Cresswell KM, Sheikh A. Information technology-based approaches to reducing

repeat drug exposure in patients with known drug allergies. J Allergy Clin Immunol

2008; 121(5): 1112-7.e7.

35. Cullen DJ, Bates DW, Small SD, Cooper JB, Nemeskal AR, Leape LL. The

incident reporting system does not detect adverse drug events: a problem for quality

improvement. Jt Comm J Qual Improv 1995; 21(10): 541-8.

36. Cullen DJ, Sweitzer BJ, Bates DW, Burdick E, Edmondson A, Leape LL.

Preventable adverse drug events in hospitalized patients: a comparative study of

intensive care and general care units. Crit Care Med 1997; 25(8): 1289-97.

Page 7: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

7

37. Cunningham G, Dodd TR, Grant DJ, McMurdo ME, Richards RM. Drug-related

problems in elderly patients admitted to Tayside hospitals, methods for prevention

and subsequent reassessment. Age Ageing 1997; 26(5): 375-82.

38. Cunningham G, Dodd TRP, Grant DJ, McMurdo MET, Richards RME.

Preventability of drug related problems in elderly patients in the community. Pharm

J 1997; 259(6968 Suppl): R2.

39. Curtiss FR. Preventable drug-related morbidity. Preventable drug-related morbidity

(PDRM). J Managed Care Pharm 2003; 9(2): 178.

40. Dago Martinez A. Arcos Gonzalez P. Alvarez de Toledo Saavedra F. Baena Parejo

MI. Martinez Olmos J. Gorostiza Ormaetxe I. Indicadores de riesgo de morbilidad

prevenible. [Risk indicators of preventable morbidity related to drug utilization.]

Gac Sanit 2007; 21(1): 29-36.

41. Darchy B, Le Mière E, Figuérédo B, Bavoux E, Domart Y. Iatrogenic diseases as a

reason for admission to the intensive care unit: incidence, causes, and

consequences. Arch Intern Med 1999; 159(1): 71-8

42. Davies EC, Green CF, Taylor S, Williamson PR, Mottram DR, Pirmohamed M.

Adverse drug reactions in hospital in-patients: a prospective analysis of 3695

patient-episodes. PLoS One 2009; 4(2): e4439.

43. Davis P, Lay-Yee R, Briant R, Ali W, Scott A, Schug S. Adverse events in New

Zealand public hospitals. II: preventability and clinical context. N Z Med J 2003;

116(1183): U624.

Page 8: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

8

44. Davis P, Lay-Yee R, Briant R, Ali W, Scott A, Schug S. Adverse events in New

Zealand public hospitals I: occurrence and impact. N Z Med J 2002; 115(1167):

U271.

45. Davis P, Lay-Yee R, Briant R, Scott A. Preventable in-hospital medical injury

under the "no fault" system in New Zealand. Qual Saf Health Care 2003; 12(4):

251-6.

46. Dormann H, Neubert A, Criegee-Rieck M, Egger T, Radespiel-Tröger M, Azaz-

Livshits T, Levy M, Brune K, Hahn EG. Readmissions and adverse drug reactions

in internal medicine: the economic impact. J Intern Med 2004; 255(6): 653-63

47. Doucet J, Jego A, Noel D, Geffroy CE, Capet C, Coquard A, Couffin E, Fauchais

AL, Chassagne P, Mouton-Schleifer D, Bercoff E. Preventable and non-preventable

risk factors for adverse drug events related to hospital admissions in the elderly: a

prospective study. Clin Drug Investig 2002; 22 (6): 385-92.;

48. Ducharme, M M. Boothby, L A. Analysis of adverse drug reactions for

preventability. Int J Clin Pract 2007; 61(1): 157-61.

49. Easton-Carter KL, Chapman CB, Brien JE. Emergency department attendances

associated with drug-related problems in paediatrics. J Paediatr Child Health 2003;

39(2): 124-9.

50. Fernández-Llimós F, Tuneu L, Baena MI, Garcia-Delgado A, Faus MJ.Morbidity

and mortality associated with pharmacotherapy. Evolution and current concept of

drug-related problems. Curr Pharm Des 2004; 10(31): 3947-67.

Page 9: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

9

51. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the

Beers criteria for potentially inappropriate medication use in older adults: results of

a US consensus panel of experts. Arch Intern Med 2003; 163(22): 2716-24.

52. Field TS, Gurwitz JH, Harrold LR, Rothschild J, DeBellis KR, Seger AC, Auger

JC, Garber LA, Cadoret C, Fish LS, Garber LD, Kelleher M, Bates DW. Risk

factors for adverse drug events among older adults in the ambulatory setting. J Am

Geriatr Soc 2004; 52(8): 1349-54.

53. Field TS, Gurwitz JH, Harrold LR, Rothschild JM, Debellis K, Seger AC, Fish LS,

Garber L, Kelleher M, Bates DW. Strategies for detecting adverse drug events

among older persons in the ambulatory setting. J Am Med Inform Assoc 2004;

11(6): 492-8.

54. Flanagan PS, MacKinnon NJ, Bowles SK, Kirkland SA. Validation of four clinical

indicators of preventable drug-related morbidity. Ann Pharmacother 2004; 38(1):

20-4.

55. Forster AJ, Halil RB, Tierney MG. Pharmacist surveillance of adverse drug events.

Am J Health Syst Pharm 2004; 61(14): 1466-72.

56. Forster AJ, Murff HJ, Peterson JF, Gandhi TK, Bates DW. Adverse drug events

occurring following hospital discharge. J Gen Intern Med 2005; 20(4): 317-23.

57. Forster AJ, Rose NG, van Walraven C, Stiell I. Adverse events following an

emergency department visit. Qual Saf Health Care 2007; 16(1): 17-22.

58. Franceschi M. Scarcelli C. Niro V. Seripa D. Pazienza A.M. Pepe G. Colusso A.M.

Pacilli L. Pilotto A. Prevalence, clinical features and avoidability of adverse drug

Page 10: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

10

reactions as cause of admission to a geriatric unit: a prospective study of 1756

patients. Drug Saf 2008; 31(6): 545-56.

59. Gandhi TK, Seger DL, Bates DW. Identifying drug safety issues: from research to

practice. Int J Qual Health Care 2000; 12(1): 69-76.

60. Gandhi TK, Weingart SN, Borus J, Seger AC, Peterson J, Burdick E, Seger DL,

Shu K, Federico F, Leape LL, Bates DW. Adverse drug events in ambulatory care.

N Engl J Med 2003; 348(16): 1556-64.

61. Gandhi TK, Weingart SN, Seger AC, Borus J, Burdick E, Poon EG, Leape LL,

Bates DW. Outpatient prescribing errors and the impact of computerized

prescribing. J Gen Intern Med 2005; 20(9): 837-41.

62. García V, Marquina I, Olabarri A, Miranda G, Rubiera G, Baena MI. Resultados

negativos asociados con la medicacion en un servicio de urgencias hospitalario.

[Negative results associated with medication in the emergency department of a

hospital.] Farm Hosp 2008; 32(3): 157-62.

63. Gianino MM, Foti G, Borghese R, Lorelli S, Siliquini R, Renga G. Indicators for

preventable drug-related morbidity. Practical application in home-based care.

Pharmacoepidemiol Drug Saf 2008; 17(5): 501-10.

64. Gosney M, Tallis R.Prescription of contraindicated and interacting drugs in elderly

patients admitted to hospital. Lancet 1984; 2(8402): 564-7.

65. Grenouillet-Delacre M, Verdoux H, Moore N, Haramburu F, Miremont-Salamé G,

Etienne G, Robinson P, Gruson D, Hilbert G, Gabinski C, Bégaud B, Molimard M.

Life-threatening adverse drug reactions at admission to medical intensive care: a

prospective study in a teaching hospital. Intensive Care Med 2007; 33(12): 2150-7.

Page 11: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

11

66. Gurwitz JH, Field TS, Avorn J, McCormick D, Jain S, Eckler M, Benser M,

Edmondson AC, Bates DW. Incidence and preventability of adverse drug events in

nursing homes. Am J Med 2000; 109(2): 87-94.

67. Gurwitz JH, Field TS, Harrold LR, Rothschild J, Debellis K, Seger AC, Cadoret C,

Fish LS, Garber L, Kelleher M, Bates DW. Incidence and preventability of adverse

drug events among older persons in the ambulatory setting. JAMA 2003; 289(9):

1107-16.

68. Gurwitz JH, Field TS, Judge J, Rochon P, Harrold LR, Cadoret C, Lee M, White K,

LaPrino J, Erramuspe-Mainard J, DeFlorio M, Gavendo L, Auger J, Bates DW. The

incidence of adverse drug events in two large academic long-term care facilities.

Am J Med 2005; 118(3): 251-8.

69. Gurwitz JH, Field TS, Radford MJ, Harrold LR, Becker R, Reed G, DeBellis K,

Moldoff J, Verzier N. The safety of warfarin therapy in the nursing home setting.

Am J Med 2007; 120(6): 539-44.

70. Gurwitz JH, Field TS, Rochon P, Judge J, Harrold LR, Bell CM, Lee M, White K,

LaPrino J, Erramuspe-Mainard J, DeFlorio M, Gavendo L, Baril JL, Reed G, Bates

DW. Effect of computerized provider order entry with clinical decision support on

adverse drug events in the long-term care setting. J Am Geriatr Soc 2008; 56(12):

2225-33.

71. Hallas J, Gram LF, Grodum E, Damsbo N, Brøsen K, Haghfelt T, Harvald B, Beck-

Nielsen J, Worm J, Jensen KB, Davidsen O, Frandsen NE, Hagen C, Andersen M,

Frølund F, Kromann-Andersen H, Schou J. Drug related admissions to medical

wards: a population based survey. Br J Clin Pharmacol 1992; 33(1): 61-8.

Page 12: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

12

72. Hallas J, Harvald B, Gram LF, Grodum E, Brøsen K, Haghfelt T, Damsbo N. Drug

related hospital admissions: the role of definitions and intensity of data collection,

and the possibility of prevention. J Intern Med 1990; 228(2): 83-90.

73. Hanlon JT, Pieper CF, Hajjar ER, Sloane RJ, Lindblad CI, Ruby CM, Schmader

KE. Incidence and predictors of all and preventable adverse drug reactions in frail

elderly persons after hospital stay. J Gerontol A Biol Sci Med Sci 2006; 61(5): 511-

5.

74. Hansen RA, Greene SB, Williams CE, Blalock SJ, Crook KD, Akers R, Carey TS.

Types of medication errors in North Carolina nursing homes: a target for quality

improvement. Am J Geriatr Pharmacother 2006; 4(1): 52-61.

75. Hartwig SC. Siegel J. Schneider PJ. Preventability and severity assessment in

reporting adverse drug reactions. Am J Hosp Pharm 1992; 49(9): 2229-32.

76. Hayward RA, Hofer TP. Estimating hospital deaths due to medical errors:

preventability is in the eye of the reviewer. JAMA 2001; 286(4): 415-20.

77. Holdsworth MT, Fichtl RE, Raisch DW, Hewryk A, Behta M, Mendez-Rico E,

Wong CL, Cohen J, Bostwick S, Greenwald BM. Impact of computerized

prescriber order entry on the incidence of adverse drug events in pediatric

inpatients. Pediatrics 2007; 120(5): 1058-66.

78. Hopf Y, Watson M, Williams D. Adverse-drug-reaction related admissions to a

hospital in Scotland. Pharm World Sci 2008; 30(6): 854-62.

79. Howard RL, Avery AJ, Howard PD, Partridge M. Investigation into the reasons for

preventable drug related admissions to a medical admissions unit: observational

study. Qual Saf Health Care 2003; 12(4): 280-5.

Page 13: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

13

80. Hwang SH, Lee S, Koo HK, Kim Y. Evaluation of a computer-based adverse-drug-

event monitor. Am J Health Syst Pharm 2008; 65(23): 2265-72.

81. Imbs JL, Pletan Y, Spriet A. Evaluation de la iatrogénèse médicamenteuse évitable:

méthodologie. [Assessment of preventable iatrogenic drug therapy: methodology.

Round Table No 2 at Giens XIII.] Therapie 1998; 53: 365-70

82. MacKinnon NJ, Hepler CD. Preventable drug-related morbidity in older adults 1.

Indicator development. J Manag Care Pharm 2002; 8(5): 365-71.

83. Jain S, Basu S, Parmar VR. Medication errors in neonates admitted in intensive

care unit and emergency department. Indian J Med Sci 2009; 63(4): 145-51.

84. Jönsson AK, Hakkarainen KM, Spigset O, Druid H, Hiselius A, Hägg S.

Preventable drug related mortality in a Swedish population. Pharmacoepidemiol

Drug Saf 2010; 19(2): 211-5.

85. Jonville-Béra AP, Saissi H, Bensouda-Grimaldi L, Beau-Salinas F, Cissoko H,

Giraudeau B, Autret-Leca E. Avoidability of adverse drug reactions spontaneously

reported to a French regional drug monitoring centre. Drug Saf 2009; 32(5): 429-

40.

86. Joshua L, Devi P, Guido S. Adverse drug reactions in medical intensive care unit of

a tertiary care hospital. Pharmacoepidemiol Drug Saf 2009; 18(7): 639-45.

87. Kanjanarat P, Winterstein AG, Johns TE, Hatton RC, Gonzalez-Rothi R, Segal R.

Nature of preventable adverse drug events in hospitals: a literature review. Am J

Health Syst Pharm 2003; 60(17): 1750-9.

Page 14: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

14

88. Kaushal R, Bates DW, Abramson EL, Soukup JR, Goldmann DA. Unit-based

clinical pharmacists' prevention of serious medication errors in pediatric inpatients.

Am J Health Syst Pharm 2008; 65(13): 1254-60.

89. Kelly WN. Potential risks and prevention. Part 1: Fatal adverse drug events. Am J

Health Syst Pharm 2001; 58(14): 1317-24.

90. Kelly WN. Potential risks and prevention. Part 2: Drug-induced permanent

disabilities. Am J Health Syst Pharm 2001; 58(14): 1325-9.

91. Kelly WN. Potential risks and prevention. Part 4: Reports of significant adverse

drug events. Am J Health Syst Pharm 2001; 58(15): 1406-12.

92. Klarin I, Wimo A, Fastbom J. The association of inappropriate drug use with

hospitalisation and mortality: a population-based study of the very old. Drugs

Aging 2005; 22(1): 69-82.

93. Kopp BJ, Erstad BL, Allen ME, Theodorou AA, Priestley G. Medication errors and

adverse drug events in an intensive care unit: direct observation approach for

detection. Crit Care Med 2006; 34(2): 415-25.

94. Krähenbühl-Melcher A, Schlienger R, Lampert M, Haschke M, Drewe J,

Krähenbühl S. Drug-related problems in hospitals: a review of the recent literature.

Drug Saf 2007; 30(5): 379-407.

95. Kucukarslan SN, Peters M, Mlynarek M, Nafziger DA. Pharmacists on rounding

teams reduce preventable adverse drug events in hospital general medicine units.

Arch Intern Med 2003; 163(17): 2014-8.

96. Kunac DL, Kennedy J, Austin N, Reith D. Incidence, preventability, and impact of

Adverse Drug Events (ADEs) and potential ADEs in hospitalized children in New

Page 15: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

15

Zealand: a prospective observational cohort study. Paediatr Drugs 2009; 11(2):

153-60.

97. Kunac DL, Reith DM, Kennedy J, Austin NC, Williams SM. Inter- and intra-rater

reliability for classification of medication related events in paediatric inpatients.

Qual Saf Health Care 2006; 15(3): 196-201.

98. Kunac DL, Reith DM. Identification of priorities for medication safety in neonatal

intensive care. Drug Saf 2005; 28(3): 251-61.

99. Kunac DL, Reith DM. Preventable medication-related events in hospitalised

children in New Zealand. N Z Med J 2008; 121(1272): 17-32.

100. Kuo GM, Phillips RL, Graham D, Hickner JM. Medication errors reported by US

family physicians and their office staff. Qual Saf Health Care 2008; 17(4): 286-90.

101. Lagnaoui R, Moore N, Fach J, Longy-Boursier M, Bégaud B. Adverse drug

reactions in a department of systemic diseases-oriented internal medicine:

prevalence, incidence, direct costs and avoidability. Eur J Clin Pharmacol 2000;

56(2): 181-6.

102. Leape LL, Bates DW, Cullen DJ, Cooper J, Demonaco HJ, Gallivan T, Hallisey R,

Ives J, Laird N, Laffel G, Nemeskal R, Petersen LA, Porter K, Servi D, Shea BF,

Small SD, Sweitzer BJ, Thompson BT, Vander Vliet M; for the ADE Prevention

Study Group. Systems analysis of adverse drug events. ADE Prevention Study

Group. JAMA 1995; 274(1): 35-43.

103. Leape LL, Cullen DJ, Clapp MD, Burdick E, Demonaco HJ, Erickson JI, Bates

DW. Pharmacist participation on physician rounds and adverse drug events in the

intensive care unit. JAMA 1999; 282(3): 267-70.

Page 16: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

16

104. Leape LL, Lawthers AG, Brennan TA, Johnson WG. Preventing medical injury.

QRB Qual Rev Bull 1993; 19(5): 144-9.

105. Lehmann CU, Kim GR. Prevention of medication errors. Clin Perinatol 2005;

32(1): 107-23, vii.

106. Lepori V, Perren A, Marone C. Unerwünschte internmedizinische

Arzneimittelwirkungen bei Spitaleintritt. [Adverse internal medicine drug effects at

hospital admission.] Schweiz Med Wochenschr 1999; 129(24): 915-22.

107. MacKinnon NJ, Hepler CD. Indicators of preventable drug-related morbidity in

older adults. 2. Use within a managed care organization. J Manag Care Pharm

2003; 9(2): 134-41.

108. Marcellino K, Kelly WN. Potential risks and prevention, Part 3: Drug-induced

threats to life. Am J Health Syst Pharm 2001; 58(15): 1399-405.

109. McDonnell PJ, Jacobs MR. Hospital admissions resulting from preventable adverse

drug reactions. Ann Pharmacother 2002; 36(9): 1331-6.

110. Melmon KL. Preventable drug reactions—causes and cures. N Engl J Med 1971;

284(24): 1361-8.

111. Miller GC, Britth HC, Valenti L. Adverse drug events in general practice patients

in Australia. Med J Aust 2006; 184(7): 321-4.

112. Mjörndal T, Boman MD, Hägg S, Bäckström M, Wiholm BE, Wahlin A, Dahlqvist

R. Adverse drug reactions as a cause for admissions to a department of internal

medicine. Pharmacoepidemiol Drug Saf 2002; 11(1): 65-72.

Page 17: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

17

113. Moore N, Lecointre D, Noblet C, Mabille M. Frequency and cost of serious adverse

drug reactions in a department of general medicine. Br J Clin Pharmacol 1998;

45(3): 301-8.

114. Morimoto T, Gandhi TK, Seger AC, Hsieh TC, Bates DW. Adverse drug events

and medication errors: detection and classification methods. Qual Saf Health Care

2004; 13(4): 306-14.

115. Morris CJ, Cantrill JA, Avery AJ, Howard RL. Preventing drug related morbidity: a

process for facilitating changes in practice. Qual Saf Health Care 2006; 15(2): 116-

21.

116. Morris CJ, Cantrill JA, Hepler CD, Noyce PR. Preventing drug-related morbidity—

determining valid indicators. Int J Qual Health Care 2002; 14(3): 183-98.

117. Morris CJ, Cantrill JA. Preventing drug-related morbidity—the development of

quality indicators. J Clin Pharm Ther 2003 Aug; 28(4): 295-305.

118. Murray MD, Ritchey ME, Wu J, Tu W. Effect of a pharmacist on adverse drug

events and medication errors in outpatients with cardiovascular disease. Arch Intern

Med 2009; 169(8): 757-63.

119. Olivier P, Caron J, Haramburu F, Imbs JL, Jonville-Béra AP, Lagier G, Sgro C,

Vial T, Montastruc JL, Lapeyr-Mestre M. Therapie. Validation d’une échelle de

mesure: exemple de l'échelle française d'évitabilité des effets indésirables

medicamenteux. [Validation of a measurement scale: example of a French Adverse

Drug Reactions Preventability Scale.] 2005; 60(1): 39-45.

120. Olivier P. Boulbes O. Tubery M. Carles P. Montastruc J.L. Lapeyre-Mestre M.

Evitabilité des effets indésirables dans un service d’admissions médicales.

Page 18: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

18

[Preventability of adverse effects in a medical emergency service.] Therapie 2001;

56: 275-8.

121. O'Mahony D, Gallagher PF. Inappropriate prescribing in the older population: need

for new criteria. Age Ageing 2008; 37(2): 138-41.

122. Otero López MJ, Alonso Hernández P, Maderuelo Fernández JA, Ceruelo Bermejo

J, Domínguez-Gil Hurlé A, Sánchez Rodríguez A. Prevalencia y factores asociados

a los acontecimientos adversos prevenibles por medicamentos que causan el

ingreso hospitalario. [Prevalence and factors associated with preventable adverse

drug events leading to hospital admission.] Farm Hosp 2006; 30(3): 161-70.

123. Otero López MJ, Bajo Bajo A, Maderuelo Fernández JA, Domínguez-Gil Hurlé A.

Evitabilidad de los acontecimientos adversos inducidos por medicamentos

detectados en un Servicio de Urgencias. [Preventable adverse drug effects at an

emergency department.] Rev Clin Esp 1999; 199(12): 796-805.

124. Otero-López MJ, Alonso-Hernández P, Maderuelo-Fernández JA, Garrido-Corro B,

Domínguez-Gil A, Sánchez-Rodríguez A. Acontecimientos adversos prevenibles

causados por medicamentos en pacientes hospitalizados. [Preventable adverse drug

events in hospitalized patients.] Med Clin (Barc) 2006; 126(3): 81-7.

125. Passarelli MC, Jacob-Filho W, Figueras A. Adverse drug reactions in an elderly

hospitalised population: inappropriate prescription is a leading cause. Drugs Aging

2005; 22(9): 767-77.

126. Patel KJ, Kedia MS, Bajpai D, Mehta SS, Kshirsagar NA, Gogtay NJ. Evaluation

of the prevalence and economic burden of adverse drug reactions presenting to the

Page 19: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

19

medical emergency department of a tertiary referral centre: a prospective study.

BMC Clin Pharmacol 2007; 7: 8

127. Patel KJ, Kedia MS, Bajpai D, Mehta SS, Kshirsagar NA, Gogtay NJ. Evaluation

of the prevalence and economic burden of adverse drug reactions presenting to the

medical emergency department of a tertiary referral centre: a prospective study.

BMC Clin Pharmacol 2007; 7: 8.

128. Pearson TF, Pittman DG, Longley JM, Grapes T, Vigliotti DJ, Mullis SR. Factors

associated with preventable adverse drug reactions. Am J Hosp Pharm 1994; 51:

2268-72.

129. Peyriere H, Cassan S, Floutard E, Riviere S, Blayac JP, Hillaire-Buys D, Le

Quellec A, Hansel S. Adverse drug events associated with hospital admission. Ann

Pharmacother 2003; 37(1): 5-11.

130. Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, Farrar K, Park

BK, Breckenridge AM. Adverse drug reactions as cause of admission to hospital:

prospective analysis of 18 820 patients. BMJ 2004; 329(7456): 15-19.

131. Pourseyed S, Fattahi F, Pourpak Z, Gholami K, Shariatpanahi SS, Moin A,

Kazemnejad A, Moin M. Adverse drug reactions in patients in an Iranian

department of internal medicine. Pharmacoepidemiol Drug Saf 2009; 18(2): 104-

10.

132. Pronovost PJ, Thompson DA, Holzmueller CG, Lubomski LH, Morlock LL.

Defining and measuring patient safety. Crit Care Clin 2005; 21(1): 1-19

133. Prudent M, Dramé M, Jolly D, Trenque T, Parjoie R, Mahmoudi R, Lang PO,

Somme D, Boyer F, Lanièce I, Gauvain JB, Blanchard F, Novella JL. Potentially

Page 20: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

20

inappropriate use of psychotropic medications in hospitalized elderly patients in

France: cross-sectional analysis of the prospective, multicentre SAFEs cohort.

Drugs Aging 2008; 25(11): 933-46.

134. Queneau P, Bergmann JF. Prévention de la iatrogénie évitable: quand la sécurité

des maladies se conjugue avec les économies de santé. [Prevention of avoidable

iatrogenic disease: when patient safety joins with health care economics.] Therapie

2001; 56(2): 163-8.

135. Queneau P. Adnet F. Bannwarth B. Carpentier F. Bouget J. Trinh-Duc A.

Emergency-department visits cause by adverse-drug events: Incidence in a French

survey; preventability and useless costs. JEUR 2008; 21(1): 22-8.

136. Queneau P. Trombert B. Carpentier F. Trinh-Duc A. Bannwarth B. Bouget J.

Adverse drug effects: a prospective study by Apnet performed in seven emergency

care units in France: propositions for preventive measures. Ann Pharm Fr 2005;

63(2): 131-42.

137. Queneau, P. Grandmottet P. Prévention de la iatrogénie evitable: le devior de

vigilance. [Prevention of avoidable iatrogenic effects: the obligation for vigilance.]

Presse Med 1998; 27(25): 1280-2.

138. Raschetti R, Morgutti M, Menniti-Ippolito F, Belisari A, Rossignoli A, Longhini P,

La Guidara C. Suspected adverse drug events requiring emergency department

visits or hospital admissions. Eur J Clin Pharmacol 1999; 54(12): 959-63.

139. Rivkin A. Admissions to a medical intensive care unit related to adverse drug

reactions. Am J Health Syst Pharm 2007; 64(17): 1840-3

Page 21: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

21

140. Robertson HA, MacKinnon NJ. Development of a list of consensus-approved

clinical indicators of preventable drug-related morbidity in older adults. Clin Ther

2002; 24(10): 1595-613.

141. Rothschild JM, Bates DW, Leape LL. Preventable medical injuries in older

patients. Arch Intern Med 2000; 160(18): 2717-28.

142. Rothschild JM, Federico FA, Gandhi TK, Kaushal R, Williams DH, Bates DW.

Analysis of medication-related malpractice claims: causes, preventability, and

costs. Arch Intern Med 2002; 162(21): 2414-20.

143. Rothschild JM, Landrigan CP, Cronin JW, Kaushal R, Lockley SW, Burdick E,

Stone PH, Lilly CM, Katz JT, Czeisler CA, Bates DW. The Critical Care Safety

Study: the incidence and nature of adverse events and serious medical errors in

intensive care. Crit Care Med 2005; 33(8): 1694-700.

144. Rothschild JM, Mann K, Keohane CA, Williams DH, Foskett C, Rosen SL,

Flaherty L, Chu JA, Bates DW. Medication safety in a psychiatric hospital. Gen

Hosp Psychiatry 2007; 29(2): 156-62.

145. Ruiz B, García M, Aguirre U, Aguirre C. Factors predicting hospital readmissions

related to adverse drug reactions. Eur J Clin Pharmacol 2008; 64(7): 715-22.

146. Sánchez Muñoz LA, Castiella Herrero J, Sanjuán Portugal FJ, Naya Manchado J,

Alfaro Alfaro MJ. Utilidad del CMBD para la detección de acontecimientos

adversos por medicamentos. [Usefulness of MBDS in detection of adverse drug

events.] An Med Interna 2007; 24(3): 113-9.

Page 22: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

22

147. Sari AB, Cracknell A, Sheldon TA. Incidence, preventability and consequences of

adverse events in older people: results of a retrospective case-note review. Age

Ageing 2008; 37(3): 265-9.

148. Schnurrer JU, Frölich JC. Zur Häufigkeit und Vermeidbarkeit von tödlichen

unerwünschten Arzneimittelwirkungen. [Incidence and prevention of lethal

undesirable drug effects.] Internist (Berl) 2003; 44(7): 889-95.

149. Schumock G.T. Thornton J.P. Focusing on the preventability of adverse drug

reactions. Hosp Pharm 1992; 27(6): 538.

150. Senst BL, Achusim LE, Genest RP, Cosentino LA, Ford CC, Little JA, Raybon SJ,

Bates DW. Practical approach to determining costs and frequency of adverse drug

events in a health care network. Am J Health Syst Pharm 2001; 58(12): 1126-32.

151. Sharifzadeh M, Rasoulinejad M, Valipour F, Nouraie M, Vaziri S. Evaluation of

patient-related factors associated with causality, preventability, predictability and

severity of hepatotoxicity during antituberculosis treatment. Pharmacol Res 2005;

51(4): 353-8.

152. Singh R, McLean-Plunckett EA, Kee R, Wisniewski A, Cadzow R, Okazaki S, Fox

C, Singh G. Experience with a trigger tool for identifying adverse drug events

among older adults in ambulatory primary care. Qual Saf Health Care 2009; 18(3):

199-204.

153. Snyder RA, Abarca J, Meza JL, Rothschild JM, Rizos A, Bates DW. Reliability

evaluation of the adapted national coordinating council medication error reporting

and prevention (NCC MERP) index. Pharmacoepidemiol Drug Saf 2007; 16(9):

1006-13.

Page 23: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

23

154. Sotoca Momblona JM, Canivell Fusté S, Alemany Vilches L, Sisó Almirall A,

Codina Jané C, Ribas Sala J. Problemas relacionados con la medicación que causan

ingresos hospitalarios. Aten Prim 2009; 41(3): 141-6.

155. Strandell J, Bate A, Lindquist M, Edwards IR; Swedish, Finnish, Interaction X-

referencing Drug-drug Interaction Database (SFINX Group). Drug-drug

interactions—a preventable patient safety issue? Br J Clin Pharmacol 2008; 65(1):

144-6.

156. Takata GS, Mason W, Taketomo C, Logsdon T, Sharek PJ. Development, testing,

and findings of a pediatric-focused trigger tool to identify medication-related harm

in US children's hospitals. Pediatrics 2008; 121(4): e927-35.

157. Tam KW, Kwok KH, Fan YM, Tsui KB, Ng KK, Ho KY, Lau KT, Chan YC, Tse

CW, Lau CM. Detection and prevention of medication misadventures in general

practice. Int J Qual Health Care 2008; 20(3): 192-9.

158. Temple ME, Robinson RF, Miller JC, Hayes JR, Nahata MC. Frequency and

preventability of adverse drug reactions in paediatric patients. Drug Saf 2004;

27(11): 819-29.

159. The Canadian Adverse Events Study. The Canadian Adverse Events Supplement.

www.cmaj.ca/cgi/content/full/170/11/1678/DC1

160. Thomas EJ, Brennan TA. Incidence and types of preventable adverse events in

elderly patients: population based review of medical records. BMJ 2000;

320(7237): 741-4.

Page 24: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

24

161. van der Hooft CS, Dieleman JP, Siemes C, Aarnoudse AJ, Verhamme KM, Stricker

BH, Sturkenboom MC. Adverse drug reaction-related hospitalisations: a

population-based cohort study. Pharmacoepidemiol Drug Saf 2008; 17(4): 365-71.

162. van Doormaal JE, Mol PG, van den Bemt PM, Zaal RJ, Egberts AC, Kosterink JG,

Haaijer-Ruskamp FM. Reliability of the assessment of preventable adverse drug

events in daily clinical practice. Qual Saf Health Care 2009; 18(1): 22-7.

163. van Doormaal JE, van den Bemt PM, Mol PG, Zaal RJ, Egberts AC, Haaijer-

Ruskamp FM, Kosterink JG. Medication errors: the impact of prescribing and

transcribing errors on preventable harm in hospitalised patients. Qual Saf Health

Care 2009; 18(1): 22-7.

164. von Laue NC, Schwappach DL, Koeck CM. The epidemiology of preventable

adverse drug events: a review of the literature. Wien Klin Wochenschr 2003;

115(12): 407-15.

165. Wang J.K. Herzog N.S. Kaushal R. Park C. Mochizuki C. Weingarten S.R.

Prevention of pediatric medication errors by hospital pharmacists and the potential

benefit of computerized physician order entry. Pediatrics 2007; 119(1): e77-85.

166. Wawruch M, Zikavska M, Wsolova L, Kuzelova M, Kahayova K, Strateny K,

Kristova V. Adverse drug reactions related to hospital admission in Slovak elderly

patients. Arch Gerontol Geriatr 2009; 48(2): 186-90.

167. Winterstein AG, Hatton RC, Gonzalez-Rothi R, Johns TE, Segal R. Identifying

clinically significant preventable adverse drug events through a hospital's database

of adverse drug reaction reports. Am J Health Syst Pharm 2002; 59(18): 1742-9.

Page 25: Supplemental Digital Content - download.lww.comdownload.lww.com/wolterskluwer_vitalstream_com/PermaLink/DSZ/A/DSZ_33...1 Drug Safety Preventability of Drug-Related Harms – Part I

25

168. Winterstein AG, Johns TE, Rosenberg EI, Hatton RC, Gonzalez-Rothi R,

Kanjanarat P. Nature and causes of clinically significant medication errors in a

tertiary care hospital. Am J Health Syst Pharm 2004; 61(18): 1908-16.

169. Winterstein AG, Sauer BC, Hepler CD, Poole C. Preventable drug-related hospital

admissions. Ann Pharmacother 2002; 36(7-8): 1238-48.

170. Woods D, Thomas E, Holl J, Altman S, Brennan T. Adverse events and preventable

adverse events in children. Pediatrics 2005; 115(1): 155-60.

171. Zandieh SO, Goldmann DA, Keohane CA, Yoon C, Bates DW, Kaushal R. Risk

factors in preventable adverse drug events in pediatric outpatients. J Pediatr 2008;

152(2): 225-31

172. Zed PJ, Abu-Laban RB, Balen RM, Loewen PS, Hohl CM, Brubacher JR, Wilbur

K, Wiens MO, Samoy LJ, Lacaria K, Purssell RA. Incidence, severity and

preventability of medication-related visits to the emergency department: a

prospective study. CMAJ 2008; 178(12): 1563-9.