supplementary figure s2: hbv whole genome, bcp, c, p, prec ... · supplementary figure s2: hbv...
TRANSCRIPT
Supplementary Figure S2: HBV whole genome, BCP, C, P, PreC, PreS1, PreS2, RT,
S, X QS at nucleotide level (A) and amino acid level (B), genetic distance at
nucleotide level (C) and amino acid level (D), dS (E) and dN (F) based on CBS and
TGS data. Red points represent the characteristics of QS of each patient for CBS.
Blue points represent the characteristics of QS of each patient for TGS. (*, P<0.05)
CBS TGS
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CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS
CBS TGS
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CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS
CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS
CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS
CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS CBS TGS
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C P PreC PreS1 PreS2 RT S X
Genome BCP C P PreC PreS1 PreS2 RT S X
Genome BCP C P PreC PreS1 PreS2 RT S X
C P PreC PreS1 PreS2 RT S X
C P PreC PreS1 PreS2 RT S X
C P PreC PreS1 PreS2 RT S X
Com
plex
ity(n
t)C
ompl
exity
(aa)
dist
ance
(nt)
dist
ance
(aa)
dSdN
*
* *
* *
*
A
B
C
D
E
F