TWENTY-EIGHTH (28TH) ANNUAL REPORT

(July, 2018 to June, 2019)

DEPARTMENT

OF

VETERINARY PHARMACOLOGY AND TOXICOLOGY

DGCN COLLEGE OF VETERINARY AND ANIMAL SCIENCES

CSK HIMACHAL PRADESH KRISHI VISHVAVIDYALAYA,

PALAMPUR - 176062 {HP}

(2019)

1. INTRODUCTION

The discipline of Veterinary Pharmacology & Toxicology came into existence as one of the

constituents of the erstwhile Department of Physiology and Pharmacology at the time of the

inception of the College in July, 1986. The discipline gained the status of an independent

Department of Pharmacology & Toxicology w.e.f. July 1st, 1991 becoming one of the core

subjects in the Veterinary profession.

The Department attained the status of Postgraduate Department with the start of PG

program leading to M.V.Sc. in Veterinary Pharmacology & Toxicology w.e.f. July 1996–97.

Since then 29 students have been passed out with M.V.Sc. degree. The thrust areas of the

Department are:

• Studies on the efficacy of medicinal plants of Himachal Pradesh for animal disease control

• Studies on the poisonous plants of Himachal Pradesh and their antidotal therapy

It is evident from this 27nd Annual Report that the Department is making steady progress

since its establishment in 1991. However, there is shortage of teaching and technical supporting

staff. In order to meet the future challenges and as per new VCI recommendations, the faculty

and technically trained supporting staff need to be provided.

2. TEACHING

a) Undergraduates Courses:

S. No. Course Title Course No. Cr. Hrs. Name of Teacher(s)

1st Semester

1. General and Systemic

Veterinary Pharmacology

VPT-311 2+1 Dr. Pallavi Bhardwaj

Dr. Prashant S Daundkar

2. Veterinary Chemotherapy VPT-411 2+0 Dr. Pallavi Bhardwaj

Dr. Prashant S Daundkar

2nd Semester

1. Veterinary Neuropharmacology VPT-321 2+1 Dr. Pallavi Bhardwaj

Dr. Prashant S Daundkar

2. Veterinary Toxicology VPT-421 2+0 Dr. Prashant S Daundkar

Dr. Pallavi Bhardwaj

3. Veterinary Clinical

Biochemistry and Laboratory

Diagnosis-II

VLD-421 0+1 Dr. Prashant S Daundkar

Veterinary Pharmacology and Toxicology (Annual System)

1. Veterinary Pharmacology and Toxicology 4+1 Dr. Pallavi Bhardwaj

Dr. Prashant S Daundkar

b) Postgraduate Courses: Nil

c) Numbers of students graduated:

Degree During last academic year Accumulated total

M.V. Sc. Nil 29

Ph.D. Nil Nil

d) National and International Level Competition: UG/MSc/PhD: Nil

e) Student got admission in National and International institutes: Nil

f) Student got job/placement in India or abroad: Nil

3. RESEARCH

a. Postgraduate Research

i) Ongoing Masters Programme: Nil

ii) Ongoing Doctoral Programme: Nil

iii) Postgraduate Research Salient Achievements: Nil

b. Research Projects in Progress:

Sr.

No.

Title of the Project Funding

Source

Budget

(Lakhs)

Year of

Start

1 “Outreach programme on Ethnoveterinary

Medicine” (Network Project)

ICAR 15.15

approx.

2007

c. Summary of research finding during the year

➢ Twenty plant samples from different areas of Kangra and Mandi District of H.P. viz.

Barot, Panchrukhi, Sulah, Baijnath, Bandla, Banuri etc. were collected and got identified

from IHBT, Palampur.

➢ Plant samples were dried, grinded and aqua-ethanolic extract were prepared. Extracts

were lyophilized and stored.

➢ Anti-neoplastic activity of five plant extracts was evaluated by SRB assay conducted on

LC-450 (Rat Leydig cell) cancer cell line at IHBT, Palampur.

d. Establishment of research collaboration with national and international institutes: Nil

e. Scientific Publications and Presentations

i) Publications

1. Pritam Kaur Sidhu, Gauravdeep Singh Waraich, Gurpreet Kaur, Prashant S. Daundkar,

Suresh Kumar Sharma and Ronette Gehring. (2018) Difference in the PK of ceftiofur in

the presence and absence of nimesulide and implications for dose determination through

PK/PD integration. Small Ruminant Research 159:18–25. (NAAS Rating = 6.97)

2. Bhardwaj, P., Sidhu, P. K., Lonare, M. K., Kaur, R., Dumka, V. K., & Rampal, S. (2018).

Pharmacokinetic‐pharmacodynamic integration of marbofloxacin after single and

repeated intravenous administration in goats. Research in Veterinary Sciences, 121, 111–

115. https://doi.org/10.1016/j.rvsc.2018.10.010 (NAAS Rating = 7.62)

3. Bhardwaj, P. and Rampal, S. (2018). Resistance against fluoroquinolones in E. coli: Role

of efflux pumps. Journal of Veterinary Pharmacology and Toxicology. 17(2): 1-7.

(Review Article)

ii). Presentations

1. Lead Paper entitled “Marbofloxacin-resistant Escherichia coli isolated from fecal flora

of healthy goats following marbofloxacin administration: Is there a link?” by Pallavi

Bhardwaj and Rampal S, presented in XVIII Annual Conference of Indian Society of

Veterinary Pharmacology and Toxicology held at College of Veterinary Science and

Animal Husbandry, Anand Agricultural University, Anand (Gujrat) w.e.f 5-7 December,

2018.

2. Oral presentation on “Effect of piperine co-administration on pharmacokinetics of

marbofloxacin in goats” by Pallavi Bhardwaj, Saloni Singla and Rampal S, in XVIII

Annual Conference of Indian Society of Veterinary Pharmacology and Toxicology held

at College of Veterinary Science and Animal Husbandry, Anand Agricultural University,

Anand (Gujrat) w.e.f 5-7 December, 2018.

3. Poster Presentation on “Pharmacokinetics of ketoprofen and its interaction with

ceftiofur and cefquinome in buffalo calves” by Daundkar P.S., Bhaskar Vemu and

Sharma S.K. in XVIII Annual Conference of Indian Society of Veterinary Pharmacology

and Toxicology held at College of Veterinary Science and Animal Husbandry, Anand

Agricultural University, Anand (Gujrat) w.e.f 5-7 December, 2018.

iii). Manuals, Books, Booklets and Bulletin

➢ Practical Manual for “Veterinary Pharmacology Paper-II (2018)” by Pallavi Bhardwaj,

Dinesh Sharma and Prashant S Daundkar.

f. Technologies or patent Developed /Registered/Research infrastructure developed: Nil

4. EXTENSION AND OUTREACH ACTIVITIES

a. Extension Publication

1. Chapter entitled “Toxicological analysis in common animal poisonings” in Training

Manual on “Diagnostic Protocols in Veterinary Medicine” for SVOs & VOs of H.P. State

Animal Husbandry Department, prepared by Dept. of Veterinary Medicine, DGCN

COVAS, by Pallavi Bhardwaj, Dinesh Sharma and Prashant S. Daundkar

2. Chapter entitled “DoyarI pSauuAaoM maoM vanaspit evaM kITnaaSak ivaYaakta” in

Training Manual prepared by Dept. of Extension Education, DGCN COVAS, by Pallavi

Bhardwaj

3. Chapter entitled “pSauAaoM maoM ivaYaa@ta ko p`qaaimak ]pcaar eMva bacaava” in

Training Manual prepared by Dept. of Extension Education, DGCN COVAS by Pallavi

Bhardwaj

b. Radio talk/TV Telecast: Nil

c. Clinical camps/trainings/extension camps/animal health camps: Nil

d. Clinical cases (routine and referrals)/disease investigations/disease outbreaks

investigated

S. No Types of samples Species Important findings

1 Total eight cases were investigated

for toxicological analysis.

Samples submitted were Rumen

liquor/stomach contents, Fodder

Leopard,

Monkey, Cow

One sample was found

positive for high

nitrate/nitrite content

sample, Liver, kidney, lung,

blood/plasma

5. PARTICIPATION IN WORKSHOP/ CONFERENCES, TRAININGS ETC.

a) Trainings:

b) Conferences/workshops/seminars/symposia:

S.

No.

Date Title Name of

Participants

Place

1. Sept. 5.9.18

to 14.9.18

ICAR sponsored short course

on “Proteomics and its

Applications in Agriculture”

Dr. Prashant

S. Daundkar

Department of Biochemistry,

College of Basic Sciences &

Humanities, PAU, Ludhiana

2. 26.2.19 to

1.3.19

“Bioinformatics tools & its

application in agriculture”

Dr. Pallavi

Bhardwaj

College of Agriculture, CSK

HPKV, Palampur, H.P.

S.

No.

Date Title Name of

Participants

Nature of

participation

1. Dec. 5-7,

2018

XVIII Annual Conference of Indian

Society of Veterinary Pharmacology and

Toxicology held at College of Veterinary

Science and Animal Husbandry, AAU,

Anand (Gujrat)

Dr. Pallavi

Bhardwaj

Lead Paper and

Oral

Presentation

2. Dec. 5-7,

2018

XVIII Annual Conference of Indian

Society of Veterinary Pharmacology and

Toxicology held at College of Veterinary

Science and Animal Husbandry, AAU,

Anand (Gujrat)

Dr. Prashant

S. Daundkar

Poster

presentation

3. 3.4.19. Attended talk delivered by Mr.

Harshavardhana Kikkeri on AI and

Robotics at CSKHPKV, Palampur

Dr. Pallavi

Bhardwaj

Participant

4. 13.4.19 Attended sensitization workshop to

develop a project on National

Agricultural Higher Education Project

(NAHEP) at CSKHPKV, Palampur

Dr. Pallavi

Bhardwaj

Participant

6. WORKSHOP/SEMINAR/TRAININGS ETC. ORGANIZED:

1. Dr. Pallavi Bhardwaj and Dr. Prashant S. Daundkar delivered lectures to farmers in Skill

Development Training Programme on “Dairy farmer/Entrepreneur” organized by Dept.

of Extension Education, DGCN COVAS, CSKHPKV, Palampur, H.P.

2. Dr. Pallavi Bhardwaj and Dr. Prashant S. Daundkar acted as Resource Person in training

on “Disease diagnosis protocol in Veterinary Medicine” for Veterinary Officers of H.P.

State Animal Husbandry Department conducted by Dept. of Veterinary Medicine, DGCN

COVAS, CSKHPKV

7. HONOURS AND AWARDS

1. Dr. Pallavi Bhardwaj is elected as Executive member of the Indian Society of Veterinary

Pharmacology and Toxicology, for 2018-2020.

2. Dr. Pallavi Bhardwaj presented Lead Paper in XVIII Annual Conference of Indian Society

of Veterinary Pharmacology and Toxicology held at College of Veterinary Science and

Animal Husbandry, AAU, Anand (Gujrat)

3. Dr. Pallavi Bhardwaj acted as Rapporteur in XVIII Annual conference of the Indian

Society of Veterinary Pharmacology and Toxicology, Dec. 5-7, 2017, held at AAU,

Aanad, Gujrat.

8. FACULTY VISITS ABROAD: Nil

9. INCOME GENERATED BY COMMERCIAL UNITS AND SERVICE WINDOWS:

Nil

10. EXTRA CURRICULUM DUTY: NCC/NSS/HOSTEL WARDEN/SPORTS ETC.:

➢ Faculty members of the Department are actively involved in various extra-curricular

activities at the University and College level viz. Entrance Examination Supervision Duty,

Anti-ragging Duty, Oath Taking Ceremony, World Veterinary Day, "Daan Utsav", Lohri

celebrations-2019, Farewells/talks organized by Faculty Club COVAS etc.

11. MISCELLANEOUS

1. Dr. Pallavi Bhardwaj is a PI and Dr. Prashant S. Daundkar is Co-PI in the research project

entitled “Outreach Programme on Ethno Veterinary Medicine”.

2. Dr. Pallavi Bhardwaj is Incharge Literary Activities of DGCN COVAS.

3. Dr. Pallavi Bhardwaj acted as Tour Incharge for Participation of Post-Graduate students

in the Zonal Level Elocution Contest held at PAU, Ludhiana on August 24, 2018.

4. Dr. Pallavi Bhardwaj accompanied the students of 4th professional B.V.Sc. & A.H. for

All India Educational Tour for 15 days.

5. Dr. Pallavi Bhardwaj was member of stage Decoration and Announcement Committee

for the conduct of CSKHPKV Inter College Youth Festival 2018-19 held on 16-17

January, 2019. Performed Stage Comparing in the opening ceremony.

6. Dr. Pallavi Bhardwaj acted as Judge and member of organizing committee in Rajbhasha

Pakhwada: Poetry and Essay Writing competition conducted by CSKHPKV, Palampur

for selection of students in State Level Inter Poetry Writing Competition.

7. Dr. Pallavi Bhardwaj was member of organizing committee to conduct the Elocution

Competition on 14.8.18 for selection of team for participation in the Zonal Level

Elocution Contest held at PAU, Ludhiana.

8. Dr. Prashant Daundkar attended Annual Review Meet of the project ‘Outreach

Programme on Ethno Veterinary Medicine’ on 10th December, 2018 at TANUVAS,

Chennai.

9. Dr, Prashant S. Daundkar performed the duty of Supervisor in the CET held by CSK

HPKV on June 8, 2019.

10. Faculty members acted as Paper setter for Annual Examination of Veterinary Pharmacist

conducted by CSKHPKV, Palampur, H.P. and Abhilashi University, Mandi, H.P.

PREPARATION OF PLANT EXTRACTS IN ROTARY EVAPORATOR

LYOPHILIZATION OF PLANT

EXTRACTS

ANNEXURES

Annexure – I (Faculty position)

S. No. Name Designation

1. Dr. Pallavi Bhardwaj Assistant Professor

2. Dr. Dinesh Sharma Assistant Professor (on study leave)

3. Dr. Prashant S Daundkar Assistant Professor

Annexure – II (Staff position)

S. No. Name Designation

1. Sh. Joginder Sharma Junior Technician

2. Sh. Naginder Kumar Contractual worker

3. Sh. Desh Raj Junior Asstt. (presently working in Dean’s

Office, DGCN COVAS)

4. Sh. Karam Chand Beldar (presently on secondment in Swan River

Flood Management Project, Haroli, Una, H.P.

Annexure –III (Budget in Rs.)

S. No. Scheme Salary/wages TA Contingency TOTAL (Rs.)

1. SFS-001-53 81,819 - 60,000 1,41,819.00

2. CDA-003-53 - - 2,60,688 2,60,688.00

3. CDA-010-53 - - 33,333 33,333.00

4. Adhoc-ICAR-214-53 - 30,000 3,85,000 4,15,000.00

ACKNOWLEDGEMENTS

I appreciate all the faculty members, office and laboratory staff of the department for their

support, devotion and assistance. The encouragement and the support extended by the Hon’ble

Vice-Chancellor, Dean COVAS, Dean PGS, Director of Research & Director of Extension

Education of the University to this Department is gratefully acknowledged. I thank Dr. Pallavi

Bhardwaj, Assistant Professor of the department for compiling this 28th Annual Report of the

Department.

Dr. Mandeep Sharma

Head