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Institute for Information Transmission Problems (Kharkevich Institute) RUSSIAN ACADEMY OF SCIENCES Visual acuity charts: comparison study Gracheva M.A., Kazakova A.A., Medvedev I.B., Rychkova S.I., Pokrovskiy D.F. Pirogov Russian National Research Medical University (RNRMU); Institute for Information Transmission Problems (Kharkevich Institute), Russian Academy of Sciences; Moscow, Russia; e-mail: [email protected] Background and aim Introduction In clinical practice, visual acuity charts are used mainly for optical correction prescribing and detecting of severe impairments. Most of the charts known are good enough for these tasks. Methods Procedure Best corrected visual acuity was assessed twice (test and retest) with three test charts in random order, monocularly and binocularly, at viewing distance 4 m. Ambient light corresponded to 250 lx, luminance of charts – to 160 Cd/m2. Results We compared test and retest data by Wilcoxon signed-rank test. In group 1, the results of test and retest were significantly different for Lea chart (p=0.003), that indictes poor repeatability; for IITP and IITP-V charts no significant differences were found (p=0.611 and p=0.807). In group 2, no significant differences were found for all three charts (p=0.727 - Lea, p=0.340 - IITP, 0.974 - IITP-V). Thus, according to our data, in group with worse visual acuity (with optic nerve atrophy and retinopathy), Lea-screener chart show worse repeatability than IITP and IITP-V chart. In group with better visual acuity (light amblyopia), all charts provided comparable results. Bland-Altman plots, designed to compare test and retest measurements (agreement between two measurements for each chart separately) shows better results for IITP-V chart. LEA chart IITP-V chart (proportional design) Pirogov Russian National Research Medical University (RNRMU) Conclusions 0.32 0.25 0.25 0.2 0.16 0.16 0.2 Для 4 м 2 1.6 1.25 1 0.8 0.63 0.5 0.63 0.5 0.4 0.4 0.32 Для 4 м 2 1.6 1.25 1.0 0.8 0.63 0.5 0.4 0.32 Для 4 м 0.25 0.2 IITP chart (linear design) Modified 3-bar optotypes IITP charts contains modified 3-bar optotypes which were shown to have better repeatability in comparison with tumbling-E [1, 2]. 42 subjects (11.1±0.2 yrs) I group Optic nerve atrophy and retinopathy 0.1 (1.0 logMAR) 15 subj. II group Light amblyopia 0.9 (0.05 logMAR) 27 subj. Subjects Lea IITP IITP-V Optical nerve atrophy and retinopathy I group p=0.003** p=0.611 p=0.807 Amblyopia II group p=0.727 p=0.340 p=0.974 Results: p-values for comparison test and retest 42nd European Conference on Visual Perception Leuven, Belgium August 25th - 29th, 2019 For precise and repeatable visual acuity assessment in children with optical nerve atrophy and retinopathy (bad visual acuity), Lea chart seems to be inappropriate because of bad repeatability. IITP charts might be better alternative for repeatable testing in medical practice. The aim of the study was to assess repeatability of Lea-screener chart and new visual acuity charts: with wide-space design (IITP) and with proportional design (IITP-V). But if you want to assess treatment results, to monitor subtle changes, to track age dynamics or to conduct precise scientific experiments, you need the chart, that 1) is precise, 2) provides repeatable and reliable results. LEA IITP All subjects Amblyopia group Optic nerve atrophy and retinopathy group IITP-V Average of two measurements (test and retest) Difference between two measures Bland-Altman plots for two repeated measurements (test and retest) Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference Mean difference Zero line +1.96 SD of the difference -1.96 SD of the difference 1. Rozhkova G, Lebedev DS, Gracheva M, Rychkova S. Optimal optotype structure for monitoring visual acuity. Proc Latv Acad Sci Sect B Nat Exact, Appl Sci. 2017;71(5):327-338. doi:10.1515/prolas-2017-0057 2. Lebedev, D. S., Belozerov, A. E., Rozhkova, G. I. (2010). The optotypes for an accurate assessment of visual acuity [Оптотипы для точной оценки остроты зрения]. Patent 2447826; 07.12.10 (in Russian). References Average visual acuity:

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  • Institute for Information Transmission Problems

    (Kharkevich Institute)

    RUSSIAN ACADEMY OF SCIENCES

    Visual acuity charts: comparison study

    Gracheva M.A., Kazakova A.A., Medvedev I.B., Rychkova S.I.,

    Pokrovskiy D.F.

    Pirogov Russian National Research Medical University (RNRMU);Institute for Information Transmission Problems (Kharkevich Institute), Russian

    Academy of Sciences;Moscow, Russia;

    e-mail: [email protected]

    Background and aim

    IntroductionIn clinical practice, visual acuity charts are used

    mainly for optical correction prescribing and detecting of severe impairments. Most of the charts known are good enough for these tasks.

    Methods

    ProcedureBest corrected visual acuity was assessed twice (test and

    retest) with three test charts in random order, monocularly and binocularly, at viewing distance 4 m.

    Ambient light corresponded to 250 lx, luminance of charts – to 160 Cd/m2.

    Results

    We compared test and retest data by Wilcoxon signed-rank test. In group 1, the results of test and retest were significantly different for Lea chart (p=0.003), that indictes poor repeatability; for IITP and IITP-V charts no significant differences were found (p=0.611 and p=0.807). In group 2, no significant differences were found for all three charts (p=0.727 - Lea, p=0.340 - IITP, 0.974 - IITP-V).

    Thus, according to our data, in group with worse visual acuity (with optic nerve atrophy and retinopathy), Lea-screener chart show worse repeatability than IITP and IITP-V chart.

    In group with better visual acuity (light amblyopia), all charts provided comparable results.

    Bland-Altman plots, designed to compare test and retest measurements (agreement between two measurements for each chart separately) shows better results for IITP-V chart.

    LEA chartIITP-V chart

    (proportional design)

    Pirogov Russian NationalResearch Medical University

    (RNRMU)

    Conclusions

    0.32

    0.25

    0.25

    0.2

    0.16

    0.16

    0.2

    Для 4 м 2

    1.6

    1.25

    1

    0.8

    0.63

    0.5

    0.63

    0.5

    0.4

    0.4

    0.32Для 4 м

    2

    1.6

    1.25

    1.0

    0.8

    0.63

    0.5

    0.4

    0.32Для 4 м

    0.25

    0.2

    IITP chart(linear design)

    Modified 3-bar optotypes

    IITP charts contains modified 3-bar optotypes which were shown to have better repeatability in comparison with tumbling-E [1, 2].

    42 subjects(11.1±0.2 yrs)

    I groupOptic nerve atrophy and retinopathy

    0.1 (1.0 logMAR) 15 subj.

    II groupLight

    amblyopia0.9

    (0.05 logMAR)27 subj.

    Subjects

    Lea IITP IITP-V

    Optical nerve atrophy and retinopathy

    I group p=0.003** p=0.611 p=0.807

    Amblyopia II group p=0.727 p=0.340 p=0.974

    Results: p-values for comparison test and retest

    42nd European Conference on Visual PerceptionLeuven, BelgiumAugust 25th - 29th, 2019

    For precise and repeatable visual acuity assessment in children with optical nerve atrophy and retinopathy (bad visual acuity), Lea chart seems to be inappropriate because of bad repeatability.

    IITP charts might be better alternative for repeatable testing in medical practice.

    The aim of the study was to assess repeatability of Lea-screener chart and new visual acuity charts: with wide-space design (IITP) and with proportional design (IITP-V).

    But if you want to assess treatment results, to monitor subtle changes, to track age dynamics or to conduct precise scientific experiments, you need the chart, that 1) is precise, 2) provides repeatable and reliable results.

    LEA IITP

    All

    su

    bje

    cts

    Am

    bly

    op

    iag

    rou

    p

    Op

    tic n

    erv

    e a

    tro

    ph

    y

    an

    d r

    eti

    no

    path

    y g

    rou

    p

    IITP-V

    Average of two measurements (test and retest)

    Diff

    ere

    nce

    betw

    een tw

    o m

    easu

    res

    Bland-Altman plots for two repeated measurements (test and retest)

    Mean difference

    Zero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean difference

    Zero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean differenceZero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean differenceZero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean differenceZero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean difference

    Zero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean difference

    Zero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean differenceZero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    Mean difference

    Zero line

    +1.96 SD of the difference

    -1.96 SD of the difference

    1. Rozhkova G, Lebedev DS, Gracheva M, Rychkova S. Optimal optotype structure for monitoring visual acuity. Proc Latv Acad Sci Sect B Nat Exact, Appl Sci. 2017;71(5):327-338. doi:10.1515/prolas-2017-00572. Lebedev, D. S., Belozerov, A. E., Rozhkova, G. I. (2010). The optotypes for an accurate assessment of visual acuity [Оптотипы для точной оценки остроты зрения]. Patent 2447826; 07.12.10 (in Russian).

    References

    Average visual acuity:

    Страница 1