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WELCOME

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Located in Brattleboro, Vermont, NutraGenesis and its affiliated companies, Tradeworks Group and Icon Group, are dedicated to the commercialization of proprietary, scientifically validated bioactive ingredients that enhance human health. Our management team possesses over 60 years of combined experience in the nutraceutical industry supplying leading dietary supplement brands in all market segments. Our functional ingredients are found in premiere food and beverage brands. Who We Are

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At Nutragenesis, our select portfolio of patented, clinically tested, efficacious, nutraceutical ingredients provides our customers with a clear competitive edge. Our dietary supplement ingredients are utilized by leading supplement brands in all market segments. Our GRAS affirmed functional ingredients are found in premiere food and beverage brands. Corporate Capabilities

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Condition-Specific Claim Categories Our portfolio of ingredients feature highly marketable, substantiated claims that address todays leading health concerns including: Stress Energy Beauty from Within Weight Management Satiety/Appetite Control Metabolic Wellness Cognitive Function Anti-Aging Immunity Cardiovascular Health Antioxidant Inflammation Response

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Found in Many Leading Dietary Supplement Brands

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Featured in Leading Functional Food and Beverage Products

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NutraGenesis Structure/Function Claims are: Substantiated by our FDA and FTC Counsel at Hyman Phelps McNamara Supported by randomized, double-blind, placebo controlled human clinical trials Supported by in-vivo and in-vitro testing

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Introducing The patented multi-functional ingredient for enhanced mind and body well-being

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Why Sensoril is the Superior Choice Multi-Functional, Multi-Patented Ingredient Substantiated Structure/Function Claims Efficacy Determined in Human Clinical Trials Well-Defined Composition Water Soluble Pure Water Extraction Without Solvents

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Sensoril is derived from the renowned Ayurvedic, adaptogenic botanical, Ashwagandha (Withania somnifera) Specially cultivated roots and leaves are regionally harvested and extracted to the highest levels of glycowithanolide bioactives in the industry Ashwagandha has been used for thousands of years as one of Ayurvedic medicines most revered revitalizers A Unique Nutraceutical Ingredient

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What is an Adaptogen? Adaptogens are a select group of botanicals that: Increase the bodys resistance to physical, chemical or biological stressors Bring the body into balance after stressors disrupt body systems Reduce stress, revitalize and rejuvenate the body with no side effects (unlike stimulants)

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Sensoril Provides Diverse Health Benefits Sensorils clinically proven adaptogenic properties substantiate the following structure/function claim areas: STRESS REDUCTION MORE RESTFUL SLEEP MENTAL FOCUS AND CLARITY REDUCED FATIGUE

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Opportunities for Sensoril in the Healthy Weight Management Category Sensorils clinically proven adaptogenic properties also substantiate the following structure/function claim areas in the healthy weight management category: REDUCTION IN STRESS-RELATED APPETITE BLOOD SUGAR BALANCE

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Stress Claims Helps increase resistance to stress, tension, and irritability Helps the body cope with stress Helps to reduce physical, emotional, and mental stress and fatigue Promotes a calming, relaxing state of mind Enhances feelings of emotional well-being

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Sleep Claims Helps promote more restful sleep Helps promote better sleep Reduces stress to help promote more restful sleep

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Mental Focus and Clarity Claims Helps enhance focus and mental stamina Helps promote mental clarity and concentration

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Reduced Fatigue Claims Increases resistance to fatigue Helps restore and sustain energy levels Boosts energy and reduces fatigue Boosts energy levels

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Chemical Composition Sensoril is standardized to contain: A minimum of 8% Glycowithanolides A minimum of 32% Oligosaccharides A maximum of 2% Withaferin A

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Hypothalamus Pituitary Adrenal Axis Stressor Hypothalamus Pituitary ACTH (Adrenocorticotropic hormone) Adrenals Glucocorticoid Hormones (Cortisol)

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Sensoril Stress Mechanism of Action Glycowithanolides, a class of steroidal lactones, structurally resemble specific corticosteroids that shut off or deactivate the stress response to protect the body against the deleterious effects of prolonged stress or overreaction to stressors.

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Its all about the Science Sensoril is supported by a randomized, double-blind placebo controlled human clinical trial. This type of trial is the Gold Standard in product efficacy validation. The Sensoril study is published in the peer review Journal of the American Nutraceutical Association (JANA)

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Clinical Trial Features 98 participants completed the trial Four dosage protocols were used: 125 mg QD 125 mg BID 250 mg BID Placebo

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Objective Assessment Criteria Cortisol and DHEA Levels in Serum Examination of Routine Blood (Hb%) Examination of Lipid Profile in Serum Fasting Blood Sugar C-Reactive Protein

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Subjective Assessment Criteria The Hamilton Anxiety Scale is a widely accepted quantifier of the severity of stress and anxiety-related symptoms In the Sensoril clinical trial, participants questionnaires were prepared utilizing a Modified Hamilton Anxiety (mHAM-A) Scale

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Subjective Features Report Study participants completed a mHAM-A questionnaire at Day 0, Day 30 and Day 60. Subjects ranked the effect on their daily life of conditions/problems using a 0-4 scale. 0 = no symptoms, 1 = occasional, 2 = mild, 3 = moderate, 4 = severe

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Subjective Assessment Criteria Areas included: Overall Measure of Stress & Anxiety Sleeplessness Memory/Concentration Fatigue/Lack of Energy Perspiration, Palpitations, Dry Mouth Irritability, Feelings of Impending Doom

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Objective Features Report for 125 mg BID after 60 Days Fasting Blood Sugar Decreased 4.7% Triglycerides Decreased 9.5% LDL Decreased 9.0% VLDL Decreased 16.6% C Reactive Protein Decreased 36.6% Serum Cortisol Decreased 24.2% Serum DHEA Increased 32.2% P value of treatment group versus placebo is as follows: Fasting Blood Sugar p