world weather open science climate conference 2014 montrÉal users, application, & social...
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WORLD WEATHER OPEN SCIENCE CLIMATE CONFERENCE
2014 MONTRÉAL
USERS, APPLICATION, & SOCIAL SCIENCE
Joint Plenary Session
21 August 2014
RESEARCH NEEDS for BETTER HEALTH RESILIENCE
to WEATHER HAZARDS
MICHEL JANCLOES
MD, MPH, DPH
Assisted by: NICHOLAS CHONG
Joint Plenary: User, Applications, and Science Program
WWOSC Montreal
21 August 2014
A Story: Malaria in Pikine
• Early acute malaria cases
• Longitudinal prospective study
• Findings: Humidity changes = transmission shift
New warning messages and interventions against malaria
M. JancloesWWOSC Montreal
21 August 2014
A new health proverb
“When baobabs blossom, use your mosquito bed nets”
M. JancloesWWOSC Montreal
21 August 2014
Science is beautiful when open to community knowledge and action
Our agenda today
This plenary:
Health Issues and Research Perspectives
Later, a special panel!
Climatic information data to improve public health
M. JancloesWWOSC Montreal
21 August 2014
Plenary presentation outline
1. Need for Operational Research
2. Experience sharing
3. Current trends
4. Strategic Research tracks
M. JancloesWWOSC Montreal
21 August 2014
Plenary presentation outline
1. Need for Operational Research
2. Experience sharing
3. Current trends
4. Strategic Research tracks
M. JancloesWWOSC Montreal
21 August 2014
Need for Operational Research
In the future: more frequent, longer and more severe weather hazards.
Predicted health impact due to:• Water/food/shelter conditions• Spread of diseases• Access to Health infrastructure and services
M. JancloesWWOSC Montreal
21 August 2014
Potential use of new Climate IC Technologies
Demand for informed decision making on: • Response preparedness• Early warning• Alert
Request of scientific evidence for investment pre appraisal and capacity building
Need for Operational Research
M. JancloesWWOSC Montreal
21 August 2014
Plenary presentation outline
1. Need for Operational Research
2. Experience sharing
3. Current trends
4. Strategic Research tracks
M. JancloesWWOSC Montreal
21 August 2014
Experience 1: MERIT
Meningitis
Environment
Risk
Information
Technologies
M. JancloesWWOSC Montreal
21 August 2014
Meningitis belt
What shape today?
Tomorrow?
•Thomson et al., 2013
M. JancloesWWOSC Montreal
21 August 2014
MERIT purposes
A network of public health and climate/environment scientists to:
Improve response timeliness to meningococcal meningitis outbreaks
AND
Influence decisions related the introduction a new preventive vaccine.
M. JancloesWWOSC Montreal
21 August 2014
Cyclic outbreaks due to conjunction of risks factors:• Root cause still not fully understood• Meningitis belt in Africa is extending• Urgent need to better capture the influence of
environmental factors on epidemics• Attention is given to
Climate changesNew climate technologies
• Services are available
Rationale for a Research Network
M. JancloesWWOSC Montreal
21 August 2014
Epidemiological pattern
Season: Dry season
December to June
Biological factors: Damaged mucosaCo-infections
Climate factors:
Humidity, dust, winds, temperature
Person to person transmissionCarriers
Social & behavioural factorsCrowded housingDisplacementsSocial gathering
Seasonal annual epidemic pattern Major cyclic outbreaks every 5-12 Y
Causal pathogen
Preventive vaccine Reactive vaccination
Thresholds for saving lives
Alert threshold (5/100 000/wk)
Alinical samples + lab confirmation
Epidemic threshold (10/100 000/wk)
Immediate mass vaccination
Strengthen case management
M. JancloesWWOSC Montreal
21 August 2014
From coordinated research works ( more than 30 institutions):
• Retrospective review of existing data (epidemiological, environmental and climatic)
Several models developed and validated during two years in five countries.
Predictive value of models in countries with and without vaccines.
M. JancloesWWOSC Montreal
21 August 2014
MERIT 7 years work
MERIT’s merits
M. JancloesWWOSC Montreal
21 August 2014
Working with a Network of research institutions and country officers.
Strengthening epidemiological surveillance.
Validating strategies between several countries.
FIND OUT MORE: WWW.HC-FOUNDATION.ORG
Plenary presentation outline
1. Need for Operational Research
2. Experience sharing
3. Current trends
4. Strategic Research tracks
M. JancloesWWOSC Montreal
21 August 2014
Experience 2: GLEAN
Global
Leptospirosis
Environmental
Action
Network
M. JancloesWWOSC Montreal
21 August 2014
GLEAN Participants
M. JancloesWWOSC Montreal
21 August 2014
Leptospirosis: a neglected disease
Endemic & epidemic disease
Increasing severity post-disaster
Adjusted due to potential underreporting:
>1,500,000 cases>100,000 deaths
A serious global zoonosis
M. JancloesWWOSC Montreal
21 August 2014
Rationale for a Research network
Major human and animal disease• YET neglected, non-detected, and under-reported
Absence of control strategy due to• Non-specific symptoms• Complex transmission• Complex pathogen agent with multiple variants
>250 sero-variants
Economic impact
Probable impact of climate change
Increasing concerns at country level and request for technical support
M. JancloesWWOSC Montreal
21 August 2014
M. JancloesWWOSC Montreal
21 August 2014
A complex epidemiology
GLEAN network components
PREDICT
Baseline Incidence?
Main drivers and predictive value?
• Climate
• Environment
• Vector demography
Predictive models and risk stratification
(to be validated at risk sites)
INTERVENE
Informing public health decision
Outbreak investigation guidelines
Operational Guidance for outbreak control
PREVENT
Evaluation of:• Rodent controls?• Chemoprophylaxi
s in humans?
Impact of animal vaccination ?
DETECT
Case definition?
Outbreak threshold?
Early diagnosis tests and case confirmation
(specificity-sensitivity)
Algorithms for outbreak detection ?
M. JancloesWWOSC Montreal
21 August 2014
Linking extreme events and outbreaks
M. JancloesWWOSC Montreal
21 August 2014
Compounding impacts of floods (AR4, IPCC):• Proving more than just a correlation to increase and/or shifts in
disease epidemiology.
Identifying the specific link will be crucial for targeting the most appropriate health determinant:
• Role of animal hosts (esp. rodents) in disease spread.
Need for understanding different patterns of outbreaks:
• Local transmission dynamics• Important for intervention program focused on control
Especially since post-outbreak management is costly
M. JancloesWWOSC Montreal
21 August 2014
Linking extreme events and outbreaks
680 cases of leptospirosis /yr with seasonal peak during the rainy season
Typhoon Pepeng: 3 October
Typhoon Ondoy: 26 September
Thousands of people displaced and housed in emergency evacuation centers
In the 2 following weeks, 505 suspect cases and 15 deaths in Manila alone!
Philippines, 2009
GLEAN: Way forward
New partnerships and new working areasPublic Health-Veterinarians-Biotechnology Industry
• Economic analysis of outbreaks• Detection strategies• Vaccine development
Public health and Research Institutions• Prediction and Early case detection
surveillance and public health intelligence• Improved coordination with meteo/climate services
M. JancloesWWOSC Montreal
21 August 2014
Lessons learnt
1. Prerequisite: Understand the knowledge and capacity gaps
2. Move from impact assessment towards risk management with a focus on vulnerability understanding.
3. Time and space downscale for developing adaptation strategies and involve the local communities
4. Enhance quality of data sets , in particular epidemiological surveillance .
5. Develop interaction between Health and MET/Climate services on a need based approach
6. Validate the relevance of new knowledge and identify backup required for implementation
M. JancloesWWOSC Montreal
21 August 2014
Still some Research traps
a) Weather/Climate kills?
b) Impact assessment leads to risk management?
c) Research meets user needs when findings are shared?
M. JancloesWWOSC Montreal
21 August 2014
Plenary presentation outline
1. Need for Operational Research
2. Experience sharing
3. Current trends
4. Strategic Research tracks
M. JancloesWWOSC Montreal
21 August 2014
Current Research trends
Policy background and recommendations from the international community:
• WMO/GFCS, WHO, the UN Summit,• Several world conferences such as ICCS, One Health…
Advocacy for health at the center of adaptation strategies.
Research needs for backing up short and long term policy decisions.
M. JancloesWWOSC Montreal
21 August 2014
Current Research trends
Using new technologies, in particular tele-information and communication.
Scaling down to local contexts with participative process.
Integrating research into Resilience development including awareness on solution gaps, vulnerability risk analysis and incremental capacity building towards anticipative interventions awareness.
M. JancloesWWOSC Montreal
21 August 2014
Plenary presentation outline
1. Need for Operational Research
2. Experience sharing
3. Current trends
4. Strategic Research tracks
M. JancloesWWOSC Montreal
21 August 2014
Strategic Research tracks
Patterns of health resilience challenges due to extreme events ( as amplified by climate change and vulnerability shift)
Synergy of observations, experiments and modeling for policy guidance
Water Safety, Food security Risks linked with extreme events and vulnerability predictions
Specificity and sensitivity Early Warning, Alert thresholds linked with vulnerability
Space Downscaling (new modeling methods)
M. JancloesWWOSC Montreal
21 August 2014
Some institutional issues
• Considering other determinants of health, should it be a priority to link meteorology and climatology for better health resilience against future weather hazards?
• Who should be involved in the design of research proposals? Who should be the key actors?
• How can we develop a sustained cooperation between met/climate offices, research institutes and public health related services?
M. JancloesWWOSC Montreal
21 August 2014
Conclusion
M. JancloesWWOSC Montreal
21 August 2014
Science is beautiful when open to community knowledge and action
A political MUST
An Applied Research Opportunity
FIND OUT MORE: WWW.HC-FOUNDATION.ORG
References
M. JancloesWWOSC Montreal
21 August 2014
• Bertherat E. 2007. Meningococcal Meningitis in Africa Overview: Response Strategies and Current Challenges. WHO
• Global Frame Work for Climate Services. Available online: http://www.gfcs-climate.org (accessed on 31 July 2014)
• Jancloes M, et al. 2014. Climate services to improve public health. Int. J. Environ. Res. Public Health. 11, p. 4555-4559.
• Jancloes M. 2013. Climate Services for Health (Presentation). WMO GFCS• MERIT Report of the 4th MERIT technical meeting (2010).• Rogers, D.P.; Tsirkunov, V. 2013. Weather and Climate Resilience Effective Preparedness through National
Meteorological and Hydrological Services; The World Bank: Washington, DC, USA. • Thomson MC, et al. 2013. A climate and health partnership to inform the prevention and control of
meningoccocal meningitis in sub-Saharan Africa: the MERIT initiative. Climate Science for Serving Society: Research, Modeling and Prediction Priorities. Geneva (Switzerland): World Health Organization; p.459–484.
• 3rd Global Leptospirosis Environmental Action Network (GLEAN) Meeting (2013).• One Health Summit. Available online: http://glean-lepto.org/component/k2/item/95-one-health-summit-17-20-
november-2013-in-davos-switzerland (accessed on 31 July 2014). • Committee on Climate, Ecosystems, Infectious Diseases, and Human Health. Under the Weather: Climate,
Ecosystems, and Infectious Disease. 2001:National Academies Press.