cdti funding: from seminconductors to digital healthphantomsfoundation.com/imaginenano/2018/... ·...
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CDTI FUNDING:
FROM SEMINCONDUCTORS
TO DIGITAL HEALTH
This report is solely for the internal use of potential partner
personnel. No part of it may be circulated, quoted, or reproduced
for distribution outside the potential partner organization without
prior written approval from AlphaSIP Group. This material was
used by AlphaSIP Group during an oral presentation; it is not a
complete record of the discussion.
BOSTON – MADRID – ZARAGOZA STRICTLY CONFIDENTIAL
AlphaSIP
• Advanced electronic medical diagnostics laboratory founded in 2008.
• Experts in infectious respiratory diseases and antibiotic resistance (PneumoSIP)
• Winner of the SME Instrument Phase 2 of the European Commission (Top 10 largest projects)
• We develop point-of-care diagnostics devices, based on nanoelectronics, lateral-flow and microfluidics, toprovide immediate and reliable results. Patented DNA based Molecular Dx
• Only Spanish company approved by Traffic Department (DGT) in drug detection
• Partnerships with national and international Universities, Technological Centers and Hospitals such asHarvard University, Universidad Complutense de Madrid, Autónoma Barcelona, University of Zaragoza,National Center for Microelectronics, CSIC- Consejo Superior de Investigaciones Científicas, CEEI Aragón,Clinical Hospitals, Miguel Servet, La Paz, Can Ruti, Clinic, La Fe and Instituto de Salud San Carlos
• Extensive market know-how and continuous investment in R&D (More than 10 European projects)
• Direct investment of more than 14 Million EUR in Product R&D (Up to 18 Million in conjunction with Bosch,ST, Philips, NXP)
• 120 exclusive patent licenses and 10 own patents
• Team of 32 employees (PhD & Engineers) and external researchers in cooperation projects.
www.alphasip.es
Madrid - Zaragoza - USA
Company Overview
Molecular Diagnostics
Antibiotic resistance & Infectious Diseases
R&D Line
R&Dconsulting projects
DOA Line
Drugs of Abuse Detection
2
Engineering
Product Portfolio 2018 in the market
DRUG TESTERSDrug SIP
SME INSTRUMENTPhase2
PneumoSIP
Pilot Line IA ECSEL& Lighthouse
Initiave
Advance Bio & Nanoelectronics
Engeneering
CDTI NEOTEC 2008 “SENDA” ENABLE FOLLOW
ON 14M EUR INVESTMENT IN R&D & 10 Patents
pneumosipdx.com
3
•Why Pneumonia?
Each year 3,4 million cases of
pneumonia are diagnosed in
Europe, costing more than € 10bn
www.alphasip.es
Madrid - Zaragoza - USA
5
10
PneumoSIP SystemPneumoSIP is a system that combines all manual laboratory steps for PCR detection
• Robotic arm and automatic pipette for preparationand pre-PCR tasks
• Thermocycler and fluorescence detector for qPCR
• Cross-contamination prevention flow system
• Internal and external bar code reader / QR
• Touch screen
11
PneumoSIP SystemPneumoSIP uses its own consumables that contains all the necessary reagents in a safe way
• Made in white room, under ISO13485
• Sealed to maintain reagent freshness until testtime
• Cost-effective, adaptable to variety of panels
• Includes bar codes / QR for identification
• Contains elements in patent process
www.alphasip.es
Madrid - Zaragoza - USA
DOA LineDrugs of Abuse Detection Line
21
www.alphasip.es
DOA LineWe have developed the FirstSafety Device for Rapid DrugDetection in Saliva.
Madrid - Zaragoza - USA
22
1. MOBILITY 4.0 (Thermostated, Saliva)2. DrugSIP DUAL Medical (Saliva & Urine)3. DrugSIP Manual
DOA ApproachBiochemical research has positioned us as the first Spanish company in Drug of Abuse Detection knowledge
www.alphasip.es
Madrid - Zaragoza - USA
31
www.alphasip.es
R&D Line: Manufacturing 4.0
AlphaSIP is the only Spanish companypresent in the Pilot Line of EuropeanManufacturing Ecsel InForMed, thatallows large scale manufacturing of chipsin the facilities of Philips and Medtronics
AlphaSIP has the support of Cerler GlobalElectronics as a priority manufacturer
Madrid - Zaragoza - USA
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Manufacturing and Distribution
Establish strategic partnerships,a number of large distributors are
searching for such products
Year 1 Year 3 Year 5 Year 7
Proof of concept
Colon Cancer
with CEA
AlphaSIP
established
ENIAC CAJAL4EU Project
. 25 MILL EUR, 30
partners, 9 countries
Licensed out 400 patents
from Nantero
CDTI SENDA D-Dimer
chip generation I.
ENIAC SILVER project
12MILL EUR Cleantech
Nanocardiococo Mill
EUR Clinical Essay
Innpacto
AvanSurf CIEN
CATRENE 3DFF
Ecsel Silense
SME Instrument
Phase II Pneumosip
Year 11
ECSEL - Informed
Penta 2 ESAIR Infineon
“Pending National GO”
11 Years of Evolution
www.alphasip.es
Beyond Core Business Line
CDTI CIEN “Avansurf” has helped to enternew business niche like cleantech, energyfinance
PID will yield to IoT works with Infineonlead business IoT
Madrid - Zaragoza - USA
18
CDTI IMPACT
NEOTEC SENDA: Proof of concept new CMOS CNTs Based
1
8Sources: The World Nanotechnology Market 2006; Nanotechnology Market Forecast to 2011; Elaboración propia
BioMEMS* (BioMEMS = BioMicroelectromechanical Devices) abarcan desde el tamaño de un SIM de teléfono móvil hasta 1000 veces el tamaño de un Globulo Rojo
Thanks to coordinate large projects AlphaSIP is part
of JTI ECSEL Governing Board (5 Bn EUR)
SAMPLE
PREPARATIONTRANSDUCTION
BIOSENSORBIOCHEMISTRYELECTRONIC
SYSTEM
DIAGNOSIS
EQUIPMENT
AlphaSIP designs, patents and outsourcesmanufacture of medical nanotechnology (fabless)
Premios y Reconocimientos
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Premio MEJOR PYME
2012
Premio Jóvenes Emprendedores – Empresa
de Base Tecnológica
Premio Redherring
2012
Premio Emtech 2011
ISCTE-IUL MIT-
Portugal Venture
Competition
Premio Emprendedores XXI
categoría CRECES XXI
Fondo Emprendedores de Repsol 2013
Premio Idea 2009
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6 tips: Learnt Lessons
CDTI is a real way of financing new start-up businesses or new business line of revenue.
Foster international exposure and proactively helps to find new partners all over the world or in any expertise domain.
Thanks to this AlphaSIP has interacted over 700 partners in 11 years of experience.
Support from technical experts from CDTI allow us to take part in large projects at a European and International level.
Our participation in large projects is a good opportunity to get in contact and take part in European Making Decisions Boards.
Timelines of R&D financed projects push your company to launch products to the market at a competitive time (without delays).
www.alphasip.es
THANKSReliability Safety Efficiency
Madrid - Zaragoza - USA
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