intro to benefits of lims - thermo fisher...

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Introduction and Business Benefits of

LIMS

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What is LIMS?

Laboratory Information Management System

A database system for maintaining an accurate record of work carried out in a laboratory environment.

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What is the purpose of LIMS

Maximize value from laboratory operations§ Improve laboratory efficiency§ Assist compliance with regulatory and quality standards

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Improving Laboratory Efficiency

§ Reduce time spent on• Locating samples• Entering and reviewing data• Calculating results• Producing reports• Communicating with the laboratory’s customers

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Assist with regulatory and quality compliance

§ Help your lab comply with• Quality standards like ISO 9000 and ISO 17025• Regulatory standards like GxP, FDA 21 CFR Pt 11• Environmental standards like ISO 14000

§ Also beneficial if your lab produces data that is• Used to confirm a product is within specifications• Used to confirm the safety of a product• Submitted to a court of law (Forensic labs, Patent protection)

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Some functional areas of a LIMS

§Management of the laboratory environment• Information about personnel, instruments, analytical procedures,

sample types, customers, products, other IT systems…§ Sample Processing

• Recording the progress of samples through the laboratory§ Results Management

• Entering results, comparing with specifications, and authorizing analytical test results

§ Reporting• Generating reports or certificates of analysis based on information

currently in the database

Static Data

Dynamic Data

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Lifecycle of a Sample

§ Sample Login§ Receiving in the lab§ Test assignment§ Result entry§ Specification checking§ Review and Authorization§ Reports

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Lifecycle of a Sample – Sample Login

(screenshot)

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Lifecycle of a Sample – Receiving in the lab

(screenshot plus picture of a barcode)

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Lifecycle of a Sample – Test Assignment

(screenshot)

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Lifecycle of a Sample – Result Entry

(screenshot plus picture of an instrument. Maybe diagram of IM)

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Lifecycle of a Sample – Specification Checking

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Lifecycle of a Sample – Reports

(picture of a C of A plus some other flashy reports)

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Other features

§ Help Productivity• Barcoding• Instrument Integration• Location tracking• Workload/resource planning• Management by exception

(Incidents etc)• Technical architecture and

impact on IT administration overhead

§ Help Compliance• Security• Operator approval• Instrument calibration and

maintenance (incl. AQC)• SQC (statistics)• E-Sigs• Vendor qualification

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Paperless lab

Before Implementation After Implementation

Greatly improved quality and productivity through massive reduction in paper and manual processes

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Example LIMS benefits within the laboratory

Laboratory Labour Saving in man/days per year Man Days per annum

Actual Saving

Introducing Bar-coding for sample receipt 2 minutes per sample 272 $40,800

Transcribing GC data into spreadsheets 4 hrs per site per day 440 $66,000

Online access for production (avoiding lab calls) 20 minutes per day per site 18 $2,700

Collecting monthly management report information 4 man days per site per month 48 $7,200

Central repository for enterprise data for customer queries 40 queries per year 15 $2,250

Updating invoicing system with sample data, batch release 10 min per sample 1248 $187,200

Automated checking of lab results 30 minutes per analyst per day 330 $49,500

$355,650

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Other examples of Benefits

§ Return on Investment with Thermo LIMS• BP: Benefit from improved specification checking. Saved nearly $2M

per year• Statoil: Integration with operations saved $800K a year through

control of blending operations. C of A Integration with finance system saved another $180K through reduced shipping (demurrage) charges

• Bristol Myers Squibb:“Estimates at one of our sites alone are that within 2 years the LIMS has saved $1 million”

• Source 2003 Thermo UGM presentations• Petrobras: (ISO 17025 service lab) Laboratory customer satisfaction

increased from 68% to 99% after implementing LIMS

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Conclusion

§ LIMS can bring multiple benefits to your business…• Laboratory Efficiency/Cost reduction• Easier/Improved compliance with quality standards (ISO 17025 etc)• Enhanced customer satisfaction

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Thank you

§Questions?§ Kevin.smith@thermofisher.com§ Booth 700