my folding vanessa morales ospina
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“COWCATCHER” ENZYME FIXES SINGLE-STRAND DNA AND PROTOCELLS MAY HAVE FORMED IN SALTY SOUP.
VANESSA MORALES OSPINA
MEDICINE STUDENT
3RD SEMESTER
INTRODUCTION
• For years the DNA molecule has been the focus of genetic and molecular studies
• This molecular structure when performing its functions is regulated by highly organized processes to ensure their proper development and function
“ COWCATCHER” ENZYME FIXES SINGLE- STRAND DNA
“Zipper” DNA
• To understand the UTMB researchers' work, it helps to picture DNA strand separation during replication as analogous to the opening of a zipper. As the "zipper" opens, it exposes strings of four uniformly spaced bases attached to each single strand of DNA.
“ COWCATCHER” ENZYME FIXES SINGLE- STRAND DNA
Nei endonuclease VIII-like 1 ( NEIL 1).
• The group of scientists from UTBM focused their study on the mechanisms of the enzyme NEIL 1 found in the single-stranded DNA and the replication complex.
“ COWCATCHER” ENZYME FIXES SINGLE- STRAND DNA
Genome
• This enzyme is very important because in the cell division, controls and
regulates many processes, also maintains the integrity of the
genome.
OBSERVATION
This news seems to me very useful and significant as
showing a responsible for repairs in our genetics also seems very important for the medical use because
with the help of this enzyme and biotechnology can be
implemented the elimination of genetic
mutations that affect our patients
PROTOCELLS MAY HAVE FORMED IN A SALTY SOUP
Cell
• This news question on a evolutionary enigma : a cell doesn't function without a cell wall, but how does the cell wall form if there is no cell?
PROTOCELLS MAY HAVE FORMED IN A SALTY SOUP
Protein synthesis
• In a solution containing the biomolecules that are
normally locked in a cell (like DNA, RNA, enzymes, proteins) these large
biomolecules clustered together spontaneously when
the salt concentration was increased.
PROTOCELLS MAY HAVE FORMED IN A SALTY SOUP
• "When biomolecules are packed together, we expect reactions to proceed much faster.
• A functioning cell must be entirely correct at once, in all its complexity,“
• “ We are now closer to Building a synthetic cell Than anyone ever before us” said the professor Huck.
OBSERVATION
This news seems very interesting because it answers
questions that has many people we have come and to
seek an explanation, I think the Professor Wilhelm Huck
essentially sought to show the cell, in medicine this is very
valuable for the development of these investigations can help prevent and improve
many diseases using synthetic cells to regenerate tissues,
organs etc.
MEDICAL UTILITYPROTOCELLS MAY HAVE FORMED IN A
SALTY SOUP
• Treatments such as synthetic cell development if it can implement this, it would mean the disappearance of malignant cell regeneration that can invade the proliferative disease patients.
MEDICAL UTILITY“ COWCATCHER” ENZYME FIXES SINGLE-
STRAND DNA
Is very important the concept of enzyme NEIL 1 level riders because of genetic diseases could invent and develop processes either from the womb to born persons, improving gene disorders can show serious affecting the morphology and neurological capacity
MEDICAL UTILITY
• These findings actually are significant in the race that is always in favor of the health and welfare of people.
BIBLIOGRAPHY
• Martínez S, lina maría. Biología molecular. 7 ed. Medellín: UPB. Fac medicina, 2012. 74-84 p.
• Radboud University Nijmegen (2013, July 2). Protocells may have formed in a salty soup.[On Line] ScienceDaily. Retrieved August 2, 2013, from http://www.sciencedaily.com /releases/2013/07/130702100115.htm.
• University of Texas Medical Branch at Galveston (2013, July 29). 'Cowcatcher' enzyme fixes single-strand DNA. [On Line]ScienceDaily. Retrieved August 2, 2013, avalaible online: from http://www.sciencedaily.com /releases/2013/07/130729161751.htm.
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