anotec toxicity and corrosivty testing

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  • 8/14/2019 Anotec Toxicity and Corrosivty Testing

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    TOX MONITOR LABORATORIES, INC.REPORT NO. TM 92-8

    D.O.T. CORROSIVITY

    Extra Strength Anotec 0307, Pure ConcentrateSAMPLE:

    SAMPLE PREPARATION: Dosed neat.

    UNABRADED SITES48 HOURS4 HOURSRabbit

    Erythema EdemaErythema EdemaNumber

    02121

    2 012 2

    01113

    4 0212

    5 21 02

    6 011 1

    CONCLUSION: Not a Corrosive Agent

    .

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    .

    Tox Monitor Laboratories, Inc.33 West Chicago AvenueOak Park. Illinois 60302

    (708) 345-6970

    TM 92-8REPORT NO.

    SAMPLE: Extra Strength Anotec 0307

    TESTS PERFORMED:

    OECD Guideline 405OECD Guideline 404

    Primary Eye IrritationAcute Dermal Irritation

    --

    Ac ute Or al To xic it y O ECD G uid eli ne 40 1OECD Guideline 403-Acute Inhalation Toxicity -OECD Guideline 402Acute Dermal Toxicity -

    EPA Guideline 81-6Sensitization -

    SUMMARY AND CONCLUSION:

    A.T. Products, sample of Extra Strength Anotec0307, was tested for toxicity in accordance withOECD Regulations. Listed below are brief summariesof the results of these studies.

    EYE IRRITATION

    There were no positive eye irritation reactionsin any of the test subjects, indicating that thesample is not an eye irritant.

    ACUTE DERMAL IRRITATION

    The maximum primary skin irritation score wasfound to be 0.33), indicating that the sample is

    not a skin irritant.

    ACUTE ORAL TOXICITY

    The acute oral LD 50 of sample was found to be greaterthan 5 g/kg body ight, indicating that the sampleis not toxic by oral ingestion at this dosage level.

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    ACUTE INHALATION TOXICITY:

    The acute inhalation of the test article at 5.02 mg/Lof air for a 4 hour period, produced no toxic effectsin the test subjects.

    ACUTE DERMAL TOXICITY:

    sample was found to be greaterThe acute dermal LD50 ofthan 2 g/kg body weight, indicating that the sample isnot toxic by dermal application.

    .

    SKIN SENSITIZATION:

    Application of sample by dermal contact using a modifiedBuehler testt produced no positive reactions indicatingthat the sample is not a skin senstizing agent.

    Michael KukulinskiStudy Director