Classical Swine FeverHog Cholera, Peste du Porc, Colera Porcina, VirusschweinepestOverview Organism Economic Impact Epidemiology Transmission Clinical Signs Diagnosis and Treatment Prevention and Control Actions to TakeCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((THE ORGANISMCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((Classical Swine Fever )irs Family Flaviviridae*+ens Pestivirs ,ipid-enveloped$ single-stranded./A virs )aries in virlence Environmentally sta!le*In tisses 0meat1*Cold temperatresCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((IMPORTANCECenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'(("istory First confirmed in %S$ (233*Endemic in late (4t# and &'t# centry*Eradicated !y late &'t# .eported in t#e %5$ (267 .ecogni8ed in 36 contries Eradication Astralia$ Canada$ /ew 9ealand$and t#e %S :ost of western and central EropeCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((Economic Impact Impact on prodction ,oss of import and e;port markets*Pigs and pork prodcts E;ample< T#e /et#erlands$ (44=-2*7'' #erds affected*(& million pigs et#ani8ed*Cost of >&?3 !illion Control*@arantine and slag#terCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((EPIDEMIOLOGYCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((+eograp#ic Distri!tion Sot# A Central America$ :e;ico Parts of Africa and Cari!!ean islands :c# of Asia .ecent ot!reaks*.ssia*BlgariaCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((:or!idity and :ortality Age and immne stats important )aries wit# viral strain*Acte "ig# mortality 0p to (''C1*S!acte ,ower mor!idity and mortality rates*C#ronic Few animals affected * always fatal*Some cases are asymptomaticCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((TRANSMISSIONCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((Animal Transmission "ig#ly contagios*Blood$ saliva$ rine$ feces$ tisses Transmission*Ingestion of contaminated gar!age or meat prodcts*Direct or indirect contact 0fomites1*,ess common< aerosol$ semen$ vectors Infected pigs are t#e only reservoirCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((ANIMALS AND CLASSICAL SWINE FEVERCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((Clinical Signs CSF) only infects pigs Inc!ation period< & to (7 days Disease varia!le*Actely fatal to asymptomatic Persistent viremia*Congenitally infected piglets*S#ed t#e virs for mont#s Signs mimic ot#er swine diseasesCenter for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((Clinical Signs< Acte Disease "ig# fever 0('DoF1 "ddling$ weakness Anore;ia ConEnctivitis Diarr#ea Staggering Cyanosis Skin #emorr#ages Deat#Center for Food Secrity and P!lic "ealt#$ Iowa State %niversity$ &'((Clinical Signs