Curriculum Vitae Personal Data Full Name: Sara Isabel Guerra Carvalhal Birth place and date: Chãs, 17 -07-1987 Nationality: Portuguese Age: 23 Institutional address: Primary Institution: Wellcome Trust Centre for Gene Regulation and Expression College of Life Sciences University of Dundee MSI/WTB/JBC Complex Dow Street Dundee DD1 5EH UK Contact Data Email: s.i.g.carvalhal@dundee.ac.uk Education 2012 – present – PhD Life Sciences Institution: University of Dundee, UK. 2008 – 2010 – Mestrado em Bioquímica Médica com especialização em Bioquímica Médica (2 years; Master degree in Biochemistry with a specialization in Medical Biochemistry) Institution: Faculty of Sciences, University of Lisbon, Portugal Final classification: 17/20 2005 – 2008 – Licenciatura em Bioquímica (3 years; 1stDegree in Biochemistry) Institution: Faculty of Sciences, University of Lisbon, Portugal Final classification: 14/20 2002 – 2005 – Ensino secundário, Curso Geral do 1º Agrupamento (3 years; Secondary Education (High school), General Course, Subject Group 1) Institution: Escola Básica e secundária (Basic and High School) Tenente Coronel Adão Carrapatoso, Vila Nova de Foz Côa, Portugal Final classification: 18/20 (The Portuguese secondary and higher education system award marks on a scale of 0 to 20; pass mark: 10)

Awards: 2012 – present – Centre for Gene Regulation and Expression PhD Programme – CLS PhD Studentship, University of Dundee, UK. 2005 – 2008 – Serviços de Acção Social da Universidade de Lisboa ( SASUL ), Portugal. The award provides funding to pay the tution fees and accommodation. 2005 – Honor award for best student. Associaçāo Juvenil Gustavo Filipe, Vila Nova de Foz Côa, Portugal. 2004 – Honor award for best student. Associaçāo Juvenil Gustavo Filipe, Vila Nova de Foz Côa, Portugal Previous and current scientific and/or professional activities January 2012 – present – PhD student Eric Griffis Lab, Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences at University of Dundee under the supervision of Dr.Eric Griffis. ALADIN/AAAS functions in miotic spindle assembly. May 2011 – November 2011 – predoctoral Fellow “Centrosoma_3D. Hacia la comprensión estructural y funcional del centrosoma” Grupo de plegamiento de proteínas del citoesqueleto, Departamento de Biología Molecular, IFMAV, Faculty of Medicine, University of Cantabria under the supervision of Prof. Juan Carlos Zabala and with Prof. Helena Soares like co-supervisor. Structural and functional characterization of a key regulator of centrosome positioning: the TBCCD1 (TBCC-domain containing 1). November 2010 – December 2011 – Team collaborator Biochemistry of Oxidants and Antioxidants Group, Centro de Química e Bioquímica, Faculty of Sciences, University of Lisbon, led by prof. H. Susana Marinho. September 2009 – December 2010 (Last year of Master) – Undergraduate student Biochemistry of Oxidants and Antioxidants Group, Centro de Química e Bioquímica, Faculty of Sciences, University of Lisbon under the supervision of Prof. Luísa Cyrne and Prof. Helena Soares. Prof. Helena Soares is also an external group of the Instituto Gulbenkian de Ciência (IGC, Oeiras)

Study of the human centrosomal protein TBCCD1 under oxidative stress conditions

induced by steady-state H2O2 treatment.

Final classification of the research project: 19/20

January 2009 – July 2009 (during the first year of Master) – Undergraduate student Biochemistry of Oxidants and Antioxidants Group, Centro de Química e Bioquímica, Faculty of Sciences, University of Lisbon, led by prof. H. Susana Marinho. Determination of anisotropy in ΔPil1p Saccharomyces cerevisiae at different temperatures. Publications Publication in Refereed Journals: Gonçalves, J; Tavares, A; Carvalhal, S and Soares, H. "Revisiting the tubulin folding pathway: new roles at centrosomes and cilia", BioMol Concepts, Vol. 1 (2010), pp. 423–434. DOI 10.1515/BMC.2010.033. Posters in conferences: Carvalhal, S; Pereira, I; Gonçalves J; Barriga Negra L; Saúde, L; Zabala, JC and Soares H. Uncovering the role of TBCCD1 in the centrosome-nucleus connection. Centrosomes and Spindle Pole Bodies Conference 2011 (EMBO Conference), 2-6 October 2011, Barcelona, Spain. Present. Gonçalves, J; Tavares, A; Carvalhal, S; Zabala, JC and Soares, H. (2010). TBCCD1 a key protein in the centrosome-nucleus connection is spread through the phylogenetic tree of life. 50th annual ASCB meeting, 11-15 December, Philadelphia, USA. Gonçalves, J; Tavares, A; Carvalhal, S; Zabala, JC and Soares, H. (2010). Human TBCCD1 is a key protein in the centrosome-nucleus connection. Why do acentrosomal organisms have it? The Centrosome: Structure, Function and Dynamics Meeting, 15-17 November, Baeza, Spain. Thesis: Carvalhal, S. (2010), "Estudo da proteína humana centrossomal TBCCD1 em condições de stress oxidativo causadas por H2O2 em estado estacionário" (Study of the human centrosomal protein TBCCD1 under oxidative stress conditions induced by steady-state H2O2 treatment), Master Thesis in Biochemistry - Medical Biochemistry, FCUL, Lisbon, PT.