founded in 1965 (almost 50 years experience)...for asme bpe / din 32676 ferrules and na-connectors...
TRANSCRIPT
Founded in 1965 (almost 50 years experience)
Global leader in Rupture Disc Manufacturing We have the Best Rupture Disc in the market!!!
Continental Disc Corporation
Why Rupture Discs?
Safeguard against under/overpressure
Protect plant and equipment
Protect the environment
Ultimate can safe lives!
Mandatory by law (code, standard, guidelines)
Chemical reactions External fire Human error Loss of electricity Loss of heating or cooling Control system / valve malfunction Overfilling Insufficient vent capacity
Why Overpressure Protection?
What can go wrong?
Overpressure protection
Vacuum protection
Pressure Vessels (Reactors, Fermenters, Blending, Filtration, Storage, etc.) WFI systems, CIP systems, Utilities Filling and packaging systems Purified water distribution Autoclaves for sterilization Thermal oxidizers Chromatography Heat exchangers Etc….
Where are discs used in Pharma?
So What is
a relief device or a Rupture Disc?
Pressure Relief Devices
Relief devices
Reclosing
Safety relief valves
Pressure/vacuum valves
Non-Reclosing
Rupture discs
Rupture pin devices
So what is a Rupture Disc?
A rupture disc, also known as a bursting disc or burst diaphragm, is a non-reclosing pressure relief device that, in most uses, protects
a pressure vessel, equipment or system from over pressurization or potentially damaging vacuum conditions.
Sometimes described as a …
Engineered Weak Spot!
Non-reclosing
Pressure relief
Device
Works on ∆P and
pressure is always
influenced by
temperature
Always
disk + holder
assembly
Generally subject
to the highest
category of PED
Important things to remember!
Benefits of a Rupture Disc?
Less material Lightweight
No Moving Parts
Less Maintenance
Clean Ability
Versatility in materials/sizes
Leak Tight
Combination
Clean Ability
Corrosion Preventions
Tight Seal
Reclosure for Containment
Available materials
Combination
Clean Ability
Corrosion Preventions
Tight Seal
Reclosure for Containment
Available materials
Where (how) to use a Rupture Disc?
Primary Relief
Secondary Relief
Series Relief
Disc Types?
Different Basic Disc-types
Forward Acting (Tension Type) • Pressure on the concave side of the disk
Reverse Acting • pressure on the convex side of the disk
Flat (Bi-Directional) • pressure acts on either side of the disk
3 important points to consider
Tolerances • Burst Tolerance • Manufacturing range • Performance Tolerance
Operating-to-burst-pressure-Ratio • 50% for flat rupture discs • 70% for forward acting discs(80% if with scoring) • 90% for reverse acting discs
Pulsating or Cycling Pressure Capability • Forward acting discs = poor resistance • Reverse acting discs = good resistance
Per
cent
of o
rigin
al b
urst
pre
ssur
e
Temperature °F
Aluminum
Stainless Steel
Nickel
Inconel
Temperature Influence
Evolution of Pharma Rupture Discs
• 1- 36”
• 0,5 – 20 bar
• OR 80%
• FRAGMENTS!
• Between flanges
• 1- 36”
• 0,5 – 20 bar
• OR 80%
• Non-fragmenting
• Between disc holder
• 1- 12” / (24”)
• 0,10 – 68,9 bar
• OR 90/95%
• Non-fragmenting
• Between disc holder
• 1- 4”
• 0,3 – 34,5 bar
• OR 90/95%
• Non-fragmenting
• Sanitary ferules
HPX/ULTRX/LOTRX SANITRX CDC(V) GRAFSERT
Special Pharma Rupture Discs
• 3- 12”
• 1 – 30 inch WC
• OR 80%
• Bi-directional
• Non-fragmenting
• Between flanges
• 3 - 8”
• 1 – 30 inch WC
• OR 80%
• Bi-directional
• Non-fragmenting
• Between ferule/clamp
• 1/4” - 1/2”
• 4,48– 1034 bar
• OR 80%
• Non-fragmenting
• Threaded holders
Screw-type rupture discs CALVAC (sanitary) CALVAC (flanged)
• Pre-bulged - media pressure on concave side of the disk
• Tensile “or stretching” burst
• Subject to fatigue caused by disc flexing (less cycling cap.)
• Generally requires a vacuum support
• Random bursting pattern (fragmenting if not scored!)
• Operating Ratio 70% up to 80%
Forward Acting Rupture Discs
Reverse Acting Rupture Discs
• Domed shape - media pressure on convex side of the disk
• Not subject to fatigue because of instant snap (flex back)
• Non-fragmenting and Full vacuum without support
• Best performance tolerances (Zero manufacturing range)
• OR is normally max 95% (100% of minimum burst pressure)
• Best for cyclic or pulsating conditions (HPX up to 250K cycles)
High Purity Rupture Discs?
High Purity Discs
Surface finish RA20
Sanitary
gaskets
Best performance
tolerances
Acc. to
ASME BPE
Optional integral burst disc Indicator
Assembly
Clean ability with Safety Valves?
Clean ability with Safety Valves?
Large L/D (deadleg area)
Why is dead leg area an issue?
Ferrule TC Connection NA Connector, flush mounted
How to Increase Clean Ability?
How to Increase Clean Ability?
Increase Clean Ability with Disc!
Or even better…!!!
NA-Connect ZERO deadleg
Tight Sealing?
High Purity Rupture Disc designs are BUBBLE TIGHT against internal or external leakage • Preserves process environment where high vacuum
conditions exist
• Provides safe working conditions under pressure
Tight Sealing “Sanitary” Gaskets
Tight Sealing “Sanitary” Gaskets
Integral “envelope” gasket (for use in standard ferrules) For ASME BPE / DIN 32676 ferrules and NA-Connectors 3A approved (designed to prevent media build-up) FDA grade and USP Class VI approved Platinum Cured Silicone, Viton (black and white); EPDM (black and white) and PTFE, etc…
Multi Bold Clamp (MBC)
232 C
121 C
22 C
34,5 69,0 103,4
Tri-Clamps only up to 121°C / 34,5barg Longer durability and better performance Under higher pressures/ temperatures Especially for PTFE gaskets
Accessories?
Integral Burst Disc Indicator
Code Compliance?
Compliance with Code/Standards
ASME Section VIII
ISO 4126
PED/CE and ATEX
ASME-BPE (2009)
USP grade Class VI
FDA approval
3A Sanitary Standard
Type design Installation issues Sizing and selection
Sanitary issues
ASME Section VIII and ISO 4126 criteria • Burst rating maximum for rupture discs
• Burst rating tolerances
• Sizing parameters for rupture discs and holders
• Rupture disc / safety valve combination design
• Marking or tagging of rupture discs
• Approved materials of construction for holders
• Product testing requirements for rupture discs/holders
• PED is mainly referring to ISO 4126
Compliance with Code/Standards
Compliance with Code/Standards
ASME BPE-2009 (Bioprocessing Equipment) • Defines surface finish options for discs and fittings
• Defines dimensions and tolerances for ferrules/clamps
• Traceability of materials of construction
• Criteria to optimize sterility and cleanability
• Marking and packaging requirements for fittings
• Elastomer performance properties (see next slide)
Compliance with Code/Standards
USP CLASS VI • Testing of elastomers for biological reactivity in vivo
• Testing of elastomers for chemical leaching impact
FDA • US federal executive departments, responsible for
protecting and promoting public health (material compatibility)
3A Sanitary Standard • Originated in the Dairy industry but has carried over to
food and pharmaceutical applications.
Conclusions!
Conclusions!
Why use Rupture Discs? • 100% leak tight (containment, Bio safety, fugitive emissions)
• Clean Ability with CIP or SIP (reduce/zero dead leg)
• Accuracy (best tolerances, fixed burst pressures, operating ratio)
• Code compliance (ASME, ISO, PED, FDA, USP, 3A)
• Versatility (Materials, pressure ranges, sizes, etc…)
Richard Neale M ike van den Bos Ronald van der Boon Product Development Regional Sales Manager Managing Director Manager CDC USA CDC NL Romynox B.V. [email protected] [email protected] [email protected] Phone: (816) 792-1500 Phone: +31 641 869 370 Phone: + 31 (0)85 877 65 78