history and scope of pharmacognosy and scope of pharmacognosy.pdf · development of pharmacognosy...
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History and Scope of
Pharmacognosy
Unit 1st
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Objectives
On completion of this period, you would be able to
know
• History
• Present status and future prospects and
• Scope of Pharmacognosy in India
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Known to Unknown
1. You might have heard the term Botany
2. What is Botany? What it deals with?
3. Have you ever heard the term Pharmacognosy?
4. If so, what it deals with?
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• Nature always stands as a golden mark to
exemplify the outstanding phenomenon of
Symbiosis
History of Pharmacognosy
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History of Pharmacognosy
Plants were used medicinally in
• China
• India
• Egypt
• Greece before beginning of the Christian era .
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History of Pharmacognosy
The Chinese system of medicine is still prevalent.
• Internal medicine Huang Di Nei Jing
Which is believed to be prepared between 200 BC
and 100 AD
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History of Pharmacognosy
Ayurveda is based on the hypothesis that
• Everything in the universe is composed of five basic
Elements.
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History of Pharmacognosy
Space
Air
Energy
Water
Matter
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History of Pharmacognosy
The oldest known herbal is Pen-tsao by
Emperor Shen Nung
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History of Pharmacognosy
A large portion of Indian population even today
depends on the
Indian System of Medicine – Ayurveda
an ancient Science of Life
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History of Pharmacognosy
• The progress achieved in Botanical studies
• During 19th Century had a direct influence on
Pharmacognosy.
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History of Pharmacognosy
• Oldest documents Papyrus Ebers written in 1500 B.C.
• Hippocrates 460 – 360 B.C known as Father of Medicine
Served the basis of discovery of medicines.
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History of Pharmacognosy
Aristotle
• Greek Philosopher
• Father of Natural History
• Made valuable contributions to Unani.
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History of Pharmacognosy
Homoeopathic system
Developed in 18th Century
• By Samuel Hahnemann
• A German Physician and Chemist
• In this System drug treatment is not specified.
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History of Pharmacognosy
• Siddha system of medicine
• Like Ayurveda, this system believes that all
objects in universe are made up of five basic
Elements
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History of Pharmacognosy
• Naturopathy is not a system of treatment which is
based on laws of Nature.
• Attention is paid to purificatory measures use of
Hydrotherapy.
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History of Pharmacognosy
• Bach Flower Remedies were discovered by
Edward Bach in the 20th Century
• 38 remedies prepared from flowers of wild plants,
bushes or trees.
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History of Pharmacognosy
• Aromatherapy begin in 4500 B.C.
• Egyptians used aromatic substances in medicines
• Prof. Gantle Fosse a French cosmetic chemist
coined the term Aromatherapy.
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History of Pharmacognosy
• Theophrastus 370 – 287 B.C presented about the
Plant kingdom.
• Dioscorides in 78 A.D gave his work De Materia
Medica.
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History of Pharmacognosy
• Greek pharmacist Galen 131 – 200 A.D.
Described various methods for preparations of
Extracts.
• Materia Medica was used for compilation of all
details about Natural products.
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History of Pharmacognosy
• Therapeutic properties of plants described in Rigveda
and Atharva Veda.
• Sarasparilla coined the word Pharmacognosy by two
words.
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History of Pharmacognosy
• Pharmakon = a drug and
• Gignosco = to acquire knowledge of it
• Pharmacognosy is scientific and systematic study of
• Structural
• Physical
• Chemical
• Biological aspects of Crude Drugs.
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History of Pharmacognosy
• An Anatomical Atlas of Powdered Vegetable Drugs
was compiled in 1904 by Greenish and Collin
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Development of Pharmacognosy
• Modern Pharmacognosy occurred during 1934 – 1960.
• This development was mainly due to some events like:
• Discovery of Pencillin in 1928
• Isolation of Resperine 1952
• Anticancer properties of Vinca rosea
• Discovery of Dioscorea was utilised to prepare
semi-synthetic steroidal hormones.
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Development of Pharmacognosy
• Pharmacognosy as an applied science
• Played a crucial role in the development of different
disciplines of science.
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Development of Pharmacognosy
• Pharmacognosy is an important link between
Pharmacology and Medicinal Chemistry
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Development of Pharmacognosy
Natural products got more and more therapeutic
importance with developments like:
• Isolation of therapeutically active constituents
• Their identification and structure elucidation.
• There is close link between structure and
Pharmacological action.
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Development of Pharmacognosy
• Natural products served the purpose of precursor
for synthesis of several medicinally important compounds.
• Some isolated components from plants were made into
different formulations and used as drugs.
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Development of Pharmacognosy
It was during this period only
• That step by step processes in Biosynthesis of Primary
and Secondary metabolites were presented before the
world.
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Development of Pharmacognosy
Knowledge of
• Plant taxonomy
• Plant breeding
• Plant pathology
• Plant genetics
Is helpful in the development of cultivation
technology for medicinal and aromatic plants.
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Present Status and Future Prospects
• Now the people have realized the utility of drugs of
natural origin which are not only economical but even
safer too.
• Active constituents from plant sources have lead to rapid
developments in Pharmacognosy and Phytochemistry.
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Present Status and Future Prospects
• Rapid developments in the fields of Chemistry
Biochemistry and Pharmacology have further
supported advancements in Pharmacognosy.
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Present Status and Future Prospects
Plants like
• Podophyllum
• Liquorice
• Valerian
• Artimisia
• Veratrum
Earlier considered to be less important but their
re-evaluation have established their utility.
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Scope of Pharmacognosy
• World Health Organisation has emphasized the
utilization of Indigenous systems of medicine based on
folklore and locally available plant materials.
• Large scale scientific cultivation of some of the
medicinally important plants is necessary.
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• Some of the products like Balsam of Tolu and Peru
Benzoin, Storax, Asafoetida, Colocynth etc.,
• If large scale cultivation of these drugs producing
plants is started we can save huge amount on
Foreign currency.
Scope of Pharmacognosy
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• Guggulsterols from Commiphora mukul
• Podophyllotoxin from Podophyllum hexandrum
• Artimisinin from Artemisia
• Annua and Silymarine from Silybuim marionum are
approved as drugs in several countries which is
encouraging news in the fields of Pharmacognosy
and Phytochemistry.
Scope of Pharmacognosy
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Scope of Pharmacognosy
Although not fully proved clinically
• Siberian ginseng Eleutherococcus senticosu
• Korean ginseng Panax ginseng
• American ginseng Panax quinquefolium
• Aswagandha with Ania somnifera are in use
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Scope of Pharmacognosy
We have not yet devised the cure by modern medicine.
• Only symptomatic relief is our reply as in case of
Arthritic disorders, AIDS & Cancer.
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