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Recent Advances in Sta.s.cs: Theory of Rough Paths Tessy Papavasiliou Department of Sta.s.cs, University of Warwick

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Page 1: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

RecentAdvancesinSta.s.cs:

TheoryofRoughPathsTessyPapavasiliou

DepartmentofSta.s.cs,UniversityofWarwick

Page 2: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Some Examples of Real Data

SeismicdataInternettrafficdata

Financialdata Albatrossflighttrajectory

I A path is ‘rough’ if change is space is not proportional tochange in time.

Page 3: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Why does roughness matter?

200 400 600 800 1000

-3

-2

-1

1

2

-2 -1 1 2

-2

-1

1

2

Ahome-madeearthquake Twoofthesignalsplo8edasapathin2d

I To understand the e↵ects of such data to systems, we need tomake sense of di↵erential equations

dYt = f (Yt) · dXt ,

where X is rough.I In order to make sense of such equations, we need to make

sense of integrals Z t

sf (Xu) · dXu.

Page 4: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Integrals and Areas

What is the meaning of

Z t

sZudXu?

-1.0 -0.5 0.5 1.0

0.5

1.0

1.5

2.0

Page 5: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Integrals and Areas

What is the meaning of

Z t

sZudXu?

-1.0 -0.5 0.5 1.0

0.5

1.0

1.5

2.0

Page 6: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Integrals and Areas

What is the meaning of

Z t

sZudXu?

-1.0 -0.5 0.5 1.0

0.5

1.0

1.5

2.0

Page 7: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Integrals and Areas

What is the meaning of

Z t

sZudXu?

-0.5 0.5 1.0

-0.8

-0.6

-0.4

-0.2

0.2

Page 8: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Integrals and Areas

What is the meaning of

Z t

sZudXu?

-0.5 0.5 1.0

-0.8

-0.6

-0.4

-0.2

0.2

Page 9: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Integrals and Areas

What is the meaning of

Z t

sZudXu?

-0.5 0.5 1.0

-0.8

-0.6

-0.4

-0.2

0.2

Page 10: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Rough Paths

I When a path is rough, the integrals are not uniquely defined.

I The first result of the theory of rough paths was to identifythe minimum number of integrals needed to identify the rest:for a path of ‘roughness p’, any integral

Z

0,Tf (Xu) · dXu

is uniquely defined, once we fix Z t

sdXu,

Z

s<u1<u2<tdXu1dXu2 , . . . ,

Z

s<u1<···<up<tdXu1 . . . dXup

!.

(Terry Lyons, 1998).

I Extension to systems that involve changes in time and space:theory of regularity structures (Martin Hairer, Fields Medal2014).

Page 11: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Rough Paths

I When a path is rough, the integrals are not uniquely defined.

I The first result of the theory of rough paths was to identifythe minimum number of integrals needed to identify the rest:for a path of ‘roughness p’, any integral

Z

0,Tf (Xu) · dXu

is uniquely defined, once we fix Z t

sdXu,

Z

s<u1<u2<tdXu1dXu2 , . . . ,

Z

s<u1<···<up<tdXu1 . . . dXup

!.

(Terry Lyons, 1998).

I Extension to systems that involve changes in time and space:theory of regularity structures (Martin Hairer, Fields Medal2014).

Page 12: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Rough Paths

I When a path is rough, the integrals are not uniquely defined.

I The first result of the theory of rough paths was to identifythe minimum number of integrals needed to identify the rest:for a path of ‘roughness p’, any integral

Z

0,Tf (Xu) · dXu

is uniquely defined, once we fix Z t

sdXu,

Z

s<u1<u2<tdXu1dXu2 , . . . ,

Z

s<u1<···<up<tdXu1 . . . dXup

!.

(Terry Lyons, 1998).

I Extension to systems that involve changes in time and space:theory of regularity structures (Martin Hairer, Fields Medal2014).

Page 13: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Signature of a Path

I The ‘iterated integrals’ provide the basic blocks forunderstanding any system driven by any path.

I All these integrals together (the ‘signature’ of the path)provide an alternative way of describing the path.(Boedihardjo et al, 2016)

I In many cases, by replacing a data stream (path) by thecorresponding signature, it is possible to capture informationmore e�ciently.

I First application: Chinese Handwriting Recognition (BenGraham, winner of 2013 competition).

Page 14: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Signature of a Path

I The ‘iterated integrals’ provide the basic blocks forunderstanding any system driven by any path.

I All these integrals together (the ‘signature’ of the path)provide an alternative way of describing the path.(Boedihardjo et al, 2016)

I In many cases, by replacing a data stream (path) by thecorresponding signature, it is possible to capture informationmore e�ciently.

I First application: Chinese Handwriting Recognition (BenGraham, winner of 2013 competition).

Page 15: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Signature of a Path

I The ‘iterated integrals’ provide the basic blocks forunderstanding any system driven by any path.

I All these integrals together (the ‘signature’ of the path)provide an alternative way of describing the path.(Boedihardjo et al, 2016)

I In many cases, by replacing a data stream (path) by thecorresponding signature, it is possible to capture informationmore e�ciently.

I First application: Chinese Handwriting Recognition (BenGraham, winner of 2013 competition).

Page 16: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Signature of a Path

I The ‘iterated integrals’ provide the basic blocks forunderstanding any system driven by any path.

I All these integrals together (the ‘signature’ of the path)provide an alternative way of describing the path.(Boedihardjo et al, 2016)

I In many cases, by replacing a data stream (path) by thecorresponding signature, it is possible to capture informationmore e�ciently.

I First application: Chinese Handwriting Recognition (BenGraham, winner of 2013 competition).

Page 17: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Capturing Sound (Daniel Wilson-Nunn, MMathStats’16)

4HE 3IGNATURE OF 3OUND

)NTRODUCTION

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3IGNATURE AND !REA

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[s,t]

r?2`2Xn

[s,t] =Z

u1Æ···Æunu1,...,unœ[s,t]

dXu1 ¢ · · · ¢ dXun.

h?2 }M�H 2H2K2Mi Q7 S(2)[s,t](X) +�M #2 2tT`2bb2/

2H2K2Mi rBb2 �b � bmKX (i,j)

[s,t] = A(i,j)[s,t] + B(i,j)

[s,t] ,

r?2`2A(i,j)

[s,t] = 12

Z

u1Æu2u1,u2œ[s1,t1]

dX (i)u1 dX (j)

u2 ≠ dX (j)u1 dX (i)

u2 ,

�M/B(i,j)

[s,t] = 12

⇣X (i)

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7Q` i, j = 1, . . . , d- �M/ X (i)t Bb i?2 p�Hm2 Q7 i?2

i@i? +QQ`/BM�i2 Q7 i?2 T�i? �i iBK2 tXA(i,j)

[s,t] Bb i?2 �`2� 2M+HQb2/ #v i?2 i?2 TH�M�` +m`p2⇣X (i)

u , X (j)u

⌘7Q` u œ [s, t]- �M/ i?2 +?Q`/ 7`QK

⇣X (i)

s , X (j)s

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Page 18: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Arabic Handwriting Recognition

Two types of handwriting recognition

OfflineImage (matrix) data

– Scanned documents

– Historical and modern documents

X =

�����

x11 x12 . . . x1n2

x21 x22 . . . x2n2

.... . .

...xn11 xn12 . . . xn1n2

�����

OnlineTimeseries data

– Data from touch devices

– Handwritten with finger or stylus

X = {(x1, y1) , (x2, y2) , . . . , (xN , yN )}

October 10, 2017 The Alan Turing InstituteA Rough Path Signature Approach to Time Series Classification

14

I Di↵erent challenge than Chinese: sequence of strokes matters.

I By including the signature as a feature of the data, Danielachieved 92.5% recognition, which is an improvement to thestate of the art (D Wilson-Nunn et al, in IEEE 2ndInternational Workshop on Arabic and Derived Script Analysisand Recognition (ASAR), 2018.)

Page 19: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

Arabic Handwriting Recognition

Two types of handwriting recognition

OfflineImage (matrix) data

– Scanned documents

– Historical and modern documents

X =

�����

x11 x12 . . . x1n2

x21 x22 . . . x2n2

.... . .

...xn11 xn12 . . . xn1n2

�����

OnlineTimeseries data

– Data from touch devices

– Handwritten with finger or stylus

X = {(x1, y1) , (x2, y2) , . . . , (xN , yN )}

October 10, 2017 The Alan Turing InstituteA Rough Path Signature Approach to Time Series Classification

14

I Di↵erent challenge than Chinese: sequence of strokes matters.

I By including the signature as a feature of the data, Danielachieved 92.5% recognition, which is an improvement to thestate of the art (D Wilson-Nunn et al, in IEEE 2ndInternational Workshop on Arabic and Derived Script Analysisand Recognition (ASAR), 2018.)

Page 20: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

RNA editing - an adapting mechanism

I Main Dogma: DNA to RNA to protein expression.

I Hypothesis: Random changes in the RNA (editing) createvariability, making cells behave di↵erently, thus allowing anindividual to adapt to change in the same way that DNAmutations help species adapt to change.

I Experiment: We are given RNA molecules from a largenumber of genetically identical cells (same DNA) of anindividual organism, subject to change. We do not knowwhich cell each RNA molecule comes from except for a smallnumber of cells (single cell experiments).

I Question: Are cells di↵erent based on the percentage ofediting of their RNA molecules?

I Statistical Challenge: We need to use single cell data toinfer variability in RNA editing among cells.

I Conclusion: RNA editing on specific sites varies sagnificantlyfrom cell to cell (Nature Communications, Harjanto et al - incollaboration with Immune Diversity group in DKFZ,Heidelberg).

Page 21: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

RNA editing - an adapting mechanism

I Main Dogma: DNA to RNA to protein expression.I Hypothesis: Random changes in the RNA (editing) create

variability, making cells behave di↵erently, thus allowing anindividual to adapt to change in the same way that DNAmutations help species adapt to change.

I Experiment: We are given RNA molecules from a largenumber of genetically identical cells (same DNA) of anindividual organism, subject to change. We do not knowwhich cell each RNA molecule comes from except for a smallnumber of cells (single cell experiments).

I Question: Are cells di↵erent based on the percentage ofediting of their RNA molecules?

I Statistical Challenge: We need to use single cell data toinfer variability in RNA editing among cells.

I Conclusion: RNA editing on specific sites varies sagnificantlyfrom cell to cell (Nature Communications, Harjanto et al - incollaboration with Immune Diversity group in DKFZ,Heidelberg).

Page 22: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

RNA editing - an adapting mechanism

I Main Dogma: DNA to RNA to protein expression.I Hypothesis: Random changes in the RNA (editing) create

variability, making cells behave di↵erently, thus allowing anindividual to adapt to change in the same way that DNAmutations help species adapt to change.

I Experiment: We are given RNA molecules from a largenumber of genetically identical cells (same DNA) of anindividual organism, subject to change. We do not knowwhich cell each RNA molecule comes from except for a smallnumber of cells (single cell experiments).

I Question: Are cells di↵erent based on the percentage ofediting of their RNA molecules?

I Statistical Challenge: We need to use single cell data toinfer variability in RNA editing among cells.

I Conclusion: RNA editing on specific sites varies sagnificantlyfrom cell to cell (Nature Communications, Harjanto et al - incollaboration with Immune Diversity group in DKFZ,Heidelberg).

Page 23: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

RNA editing - an adapting mechanism

I Main Dogma: DNA to RNA to protein expression.I Hypothesis: Random changes in the RNA (editing) create

variability, making cells behave di↵erently, thus allowing anindividual to adapt to change in the same way that DNAmutations help species adapt to change.

I Experiment: We are given RNA molecules from a largenumber of genetically identical cells (same DNA) of anindividual organism, subject to change. We do not knowwhich cell each RNA molecule comes from except for a smallnumber of cells (single cell experiments).

I Question: Are cells di↵erent based on the percentage ofediting of their RNA molecules?

I Statistical Challenge: We need to use single cell data toinfer variability in RNA editing among cells.

I Conclusion: RNA editing on specific sites varies sagnificantlyfrom cell to cell (Nature Communications, Harjanto et al - incollaboration with Immune Diversity group in DKFZ,Heidelberg).

Page 24: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

RNA editing - an adapting mechanism

I Main Dogma: DNA to RNA to protein expression.I Hypothesis: Random changes in the RNA (editing) create

variability, making cells behave di↵erently, thus allowing anindividual to adapt to change in the same way that DNAmutations help species adapt to change.

I Experiment: We are given RNA molecules from a largenumber of genetically identical cells (same DNA) of anindividual organism, subject to change. We do not knowwhich cell each RNA molecule comes from except for a smallnumber of cells (single cell experiments).

I Question: Are cells di↵erent based on the percentage ofediting of their RNA molecules?

I Statistical Challenge: We need to use single cell data toinfer variability in RNA editing among cells.

I Conclusion: RNA editing on specific sites varies sagnificantlyfrom cell to cell (Nature Communications, Harjanto et al - incollaboration with Immune Diversity group in DKFZ,Heidelberg).

Page 25: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

RNA editing - an adapting mechanism

I Main Dogma: DNA to RNA to protein expression.I Hypothesis: Random changes in the RNA (editing) create

variability, making cells behave di↵erently, thus allowing anindividual to adapt to change in the same way that DNAmutations help species adapt to change.

I Experiment: We are given RNA molecules from a largenumber of genetically identical cells (same DNA) of anindividual organism, subject to change. We do not knowwhich cell each RNA molecule comes from except for a smallnumber of cells (single cell experiments).

I Question: Are cells di↵erent based on the percentage ofediting of their RNA molecules?

I Statistical Challenge: We need to use single cell data toinfer variability in RNA editing among cells.

I Conclusion: RNA editing on specific sites varies sagnificantlyfrom cell to cell (Nature Communications, Harjanto et al - incollaboration with Immune Diversity group in DKFZ,Heidelberg).

Page 26: Recent Advances in Sta.s.cs: Theory of Rough Paths · Rough Paths I When a path is rough, the integrals are not uniquely defined. I The first result of the theory of rough paths

The Signature of an RNA molecule

UndergraduateResearchSupportSchemeprojectUndergraduateResearchSupportSchemeproject

The signature of a path An efficient way of capturing information

Author Nikolaos Constantinou / Supervisor Dr Anastasia Papavasileiou / Statistics Department

Motivation

Statistical Context

Results

Classification Rule

Conclusions

Data Simulation

References I.  Chevyrev and A. Kormilitzin, “A primer on the signature method in machine learning”, arXiv preprint arXiv:1603.03788, 2016.

II.  Chevyrev and H. Oberhauser, “Signature moments to characterise laws of stochastic processes”, arXiv preprint arXiv:1810.10971, 2018.

Nikolas Constantinou, 3rd year MORSE student.