Firdausi Qadri

Country: Bangladesh

BIOGRAPHICAL INFORMATIONSenior Scientist, Infectious Diseases Division and Head, Immunology Lab, icddr,b

Dr Qadri is the Senior Scientist, Infectious Diseases Division at icddr,b in the planning and implementation and setting up of research priorities in the field of vaccines and infectious diseases in this Centre. Also heads a large Immunology Unit composed of scientists, researchers, postgraduate students working in the laboratory, clinical and field sites for carrying out immunological, molecular biological and high throughput genomic and proteomic studies on natural infections and vaccine related responses. As leader in the Immunology Unit, research is carried out with scientists working in the laboratory, clinical and epidemiologal aspects of infectious diseases. The work is led by 8 upcoming scientists as well as 10 clinicians, 15 junior researchers, 10 MSc and 6 PhD level students as well as postdoctoral level fellows working in sandwich programs with international and national institutions. In addition over 150 staff are directly involved in supporting laboratory, clinical and field related activities in projects ongoing in the Unit.

Major interests and original scientific activities

Dr Qadri has made significant contributions to international scientific research, particularly in the field of infectious diseases with emphasis on infections which are very common in children in developing countries. Her work includes basic and applied immunology of infectious diseases but also clinical and large field based studies on enteric vaccines. Major contribution over the years has been made in microbiology and immunology of infectious diseases. Special interests are infections caused by V. cholerae, ETEC, Salmonella spp and Helicobacter pylori. The results have produced an impact in the field of enteric diseases specifically in the area of immunological and genetics and genomic mechanisms, diagnostics and vaccine development.

Over the last 5 years she has been leading the largest field studies in over 400,000 participants of an oral cholera vaccine in an urban slum in Bangladesh so as to pave the way forward for introducing cholera vaccine in high risk people in the country and in the near future in the region and globally. This has been a very important achievement in her career for providing evidence of the success of affordable vaccines that work effectively in the real life situation. The multi-directional work with the Government of Bangladesh and International experts has resulted in providing evidence and also supporting the transfer of technology of cholera vaccine to Bangladesh and its production locally which will hopefully be available at a low and affordable cost. Based on dialogues and intensive reviews, the Bill and Melinda Gates Foundation has funded the project for a period of five years with plans for expansion in Bangladesh and with hopes that the vaccine will be available regionally and in cholera prone areas.

Innovative ideas and projects have evolved on host and bacterial genetics from these vaccine studies in collaboration with the University of Gothenburg and the Wellcome Trust Sanger Institute. These studies will hopefully lead to better understanding of factors related to ‘take rate’ or failure to protection by oral vaccination.

Studies on enteric diseases have been designed based on laboratory and field based activities which together have yielded results that are world class in quality and evolved with active

collaboration with laboratories in the USA, UK and Europe. The focus has been on basic studies on the understanding of the mucosal immunology of diseases with the thrust on natural infections and its application and extension to better determining vaccine efficacy. Coupled to this is the attempt to understand the role of environmental and nutritional factors on the immune responses to natural infection and vaccines. Emphasis has been on studies of cholera, ETEC and typhoid vaccines and determining optimal methods for determining surrogate markers of protection. The hypo-responsiveness of developing country children to oral vaccines is also an area of interest.Study of genetics and genomics of host and pathogens has been important in the attempt to understand infectious diseases, population based predisposition, metagenomics and changing virulence attributes of pathogens.

Working with Centres of Excellence in the UK and USA in the field of proteomics, genomics and metagenomics, key features have been identified that can be related to causes of propensity of infections. Understanding the natural course of immune responses involving innate immunity, adaptive immunity, T and B cell responses, genomic, proteomic and high throughput studies are included within her area of interest.

Another important interest is the development of diagnostic tests for detection of enteric pathogens. This has included development of setting up of a hybridoma laboratory for production of mouse monoclonal antibodies and development of diagnostic assays for detection of V. cholerae O1/O139 and other bacterial pathogens. These monoclonal antibodies are used in Bangladesh and in other countries for diagnosis and research purposes. In addition to this, the development and testing of assays for detection of S.Typhi, S. Paratyphi, V. cholerae O1/O139, ETEC and H. pylori have been developed. One of the key achievements is the development of an immunological assay for the detection of typhoid and paratyphoid fever in febrile patients. The test has been found to be extremely important for the early detection and diagnosis of typhoid fever, a disease which has increased in incidence in Bangladesh and in the region over the last few years. This test known as the TPTest (Typhoid Paratyphoid Test) is used as a diagnostic test in the routine diagnostic laboratories as well as in nationwide typhoid surveillance being carried out with the government of Bangladesh. The conversion of this test to rapid diagnostics.

In addition to the research carried out at the icddr,b, Dr Qadri has set up the “Institute for developing science and health initiatives” (ideSHi; www.ideshi.org) in Bangladesh where national and international experts from Bangladesh and globally form the Board and advisory group. This initiative was set up by utilizing the Christophe & Rodolphe Merieux Grand Prize (€500,000) which she received from the French Academy of Sciences in 2012. The prize was given to her in 2012 as recognition of her contribution to infectious disease research. The primary focus at ideSHi, instituted at the Institute of Public Health within the Centre for Medical Biotechnology of the government of Bangladesh is on the development of science and technology in Bangladesh and encouraging scientists to work in the field of biological sciences by using the facilities offered by ideSHi and icddr,b laboratories and through networking with other institutions in the government and private sector. The focus of work relates to the detection of genetic disorders in young children but also other age groups in the country. For the first time efforts are being made in Bangladesh through ideSHi to diagnose inborn errors of metabolism and other genetic disorders to help in treatment so as to prevent irreversible damage, morbidity and mortality. The TWAS prize money received by Dr Qadri in 2013 for excellence in science

was also used to further enrich the ideSHi laboratory with equipment. This laboratory has excellent scientists, some of whom have recently relocated to the country to join the institution. International interns and scientists work to contribute and make ideSHi’s mission successful for further enhancing biomedical science. A large part of Dr. Qadri’s career has been focused in developing leaders in the field of infectious disease research from different disciplines and institutions. She has inspired many young scientists through her teaching and research activities. Her penchant for mentoring can be seen in her laboratory and field sites where aspiring fellows from both local and international universities join her team. To date, she has trained and mentored over 200 postgraduate students from Bangladesh and the region. In addition she has been involved in mentoring PhD students from the University of Gothenburg and Japan and Bangladesh. As a result of training programs and training grants received from the NIH (USA), Sida (Sweden) and European Union (Pasteur Institute, France), a network of international and national researchers have been developed. From the NIH funded D43 Fogarty and related grants, 18 MSc and 8 postdocs have been successfully completed training to attain higher levels of prominence in their field including faculty positions globally.

In summary, understanding the genetic and immunological basis of infectious diseases, genetic disorders as well as by technology transfer of research tools, vaccines and diagnostics is her aim and aspiration so as to benefit developing countries. As member of the High Level Panel of the UN Technology Bank which has been set up recently, this role is actively being pursued.

SURNAME : Firdausi Qadri Name : QadriPosition/ Title : Senior Scientist, Infectious Diseases Division

Date of Birth: 31st March 1951 Town and country of birth : Dhaka, Bangladesh

Address ( Institute)ICVB office, icddr,b,68 Shaheed tajuddin Ahmed Sarani, Mohakhali, Dhaka-1212, Bangladesh

Phone : +880-2-9827035Fax : +880-2-9827077E-mail: fqadri@icddrb.org

Nationality : Bangladeshi Gender : Male Female

DEGREES OBTAINED Year obtained

Awarding Institution

B Sc Honours in Biochemistry and Molecular BiologyPlaced /1st class 1st

1975 University of Dhaka, Bangladesh

Masters in Biochemistry and Molecular Biology Placed /1st class 1st

1977University of Dhaka, Bangladesh

PhD in Biochemistry/Immunology 1980 University of Liverpool, U.K

Postdoctoral 1986-1988 icddr,b, Bangladesh

PROFESSIONAL APPOINTMENTS FROM- to EMPLOYING INSTITUTION

Assistant & Associate Professor 1981-1988 Department of Biochemistry, University of Dhaka

Associate Scientist 1988-1993 Immunology Section, Laboratory Sciences Division, icddr,b

Scientist, and Head Immunology Section 1993-1995 Laboratory Sciences Division, icddr,bInternational Scientist, icddr,b, promoted to P-5 level based on achievements in 2008

2002- Laboratory Sciences Division, icddr,b

Director 2011 Centre for Vaccine Sciences, icddr,bSenior Director 2015 Infectious Diseases Division, icddr,bSenior Scientist 2016 Infectious Diseases Division, icddr,bMembership in academies and societies2008- Member of the scientific advisory board- Bangabandhu Sheikh Mujib Medical University, Bangladesh

2007- Adjunct Professor, Department of Mathematics and Natural Sciences, Biotechnology Unit, BRAC University

2005- Site Director and mentor for Fogarty Clinical Research Scholars2005- Mentor for infectious disease fellows and students including those from Harvard Medical School, Tufts University, and University of Gothenburg.

2003-2008 Member, Steering Committee on Diarrhoeal Disease Vaccines, World Health Organization, WHO Geneva 2000- Senior Associate, Department of International Health, Bloomberg School of Public Health1999- Member, Animal Experimentation Ethics Committee, icddr,b1990- External Examiner, BSc, MSc and PhD courses. Department of Biochemistry, Microbiology Dhaka, University. Supervisor of MSc,PhD students, research fellows from home and abroad.2009-2012 Member of the Government of Bangladesh team to the World Health Organization as advisor on cholera in Executive Board Meeting and the World Health Assembly2009- Member of GLaDNet, CHOLDINet on cholera and other diarrheal illness.2009- US Panel member of US-Japan Cooperative Medical Science Program on ‘Cholera and other Bacterial Enteric Infections2009- Member of Committee and Technical Committee on Drug Administration, Ministry of Health and Family Welfare, Government of Bangladesh2010- Member of Bangladesh Medical Research Council and its Ethical Review Committee 2010- Member, Technical Committee of the Bangladesh Drug Administration Directorate2011- Advisory Group Member of WHO Global Action Plan (GAP) for influenza vaccines2011- Member of the Coalition against Typhoid (CAT)2012- Member of the advisory group on Coalition for Cholera Prevention and Control (CCPC)2012- Member of the Committee of Action for Research, Extension and Services (CARES)2012 Member of Initiative against Diarrheal and Enteric diseases in Asia.2013 Honorary International Fellow of ASTMH.2013 Member of Global Task force on Cholera Control (GFTCC)2014 Member, Clinical Trail coordinating Committee of the Bangladesh Drug Administration 2014 Steering Committee Member of the GABRIEL Network, Fondation Mérieux2015 Member of the SAGE Working Group on oral cholera vaccine to WHO.2016 Strategic Advisory Group of Experts (SAGE) on Immunization to WHO2016 Member of the National Technical Committee on Bio-Technology of MoST.2016 Fellow of Indian National Science Academy2017 National task Force Committee (NTFC) for Laboratory Containment of Poliovirus, Bangladesh2017 Member of the Animal Experimentation Ethical review Committee ( AEERC) of DU2017 Committee of Control and Prevention of Food and Water born diseases of DGHS2017 Vaccine Investment Strategy Steering Committee of GAVI

2017 National Committee for Thalasamia Control and Prevention core Group, of DGHS, Bangladesh2017 One Health Bangladesh2017 Scientific Advisory Committee of Vaccines Against Shigella and ETEC (VASE) 2018 National Committee for Immunization Practices (NCIP) of MoH&FW2018 Member of the IsDB Scientific Advisory Board2018 South-East Asia Regional Immunization Technical Advisory Group (SEAR-ITAG) 2018 Chairman, 15th Asian Conference on Diarrhoeal Disease & Nutrition (ASCODD) Honour2006 Fellow, Infectious Diseases Society of America (FIDSA), USA2010 Fellow of the Bangladesh Academy of Sciences (BAS)2012- ASM Country Ambassador for Bangladesh2012 Elected Fellow of the Academy of Developing world (TWAS)2014 Fellow of American Academy of Microbiology2014- Member of the UN Secretary-General's High-level Panel on Technology Bank for the

Least Developed Countries (LDCs)2015 Adjunct Professor, Bangladesh University of Health SciencesAwards2006 Gold Medal for outstanding research in Biological Sciences for 2006 by the Bangladesh Academy of Science2011 Moselio Schaechter Award for scientific achievement by the American Society for Microbiology (ASM)2012 Christophe & Rodolphe Mérieux Foundation Prize, French Academy of Sciences2013 Prof. C.N.R. Rao Prize for contribution to scientific research from TWAS

Publications :Total number of original research and review articles published on vaccines and enteric infections: 334

1. Khan AI, Levin A, Chao DL, DeRoeck D, Dimitrov DT, Khan JAM, Islam MS, Ali M, Islam MT, Sarker AR, Clemens JD, Qadri F. The impact and cost-effectiveness of controlling cholera through the use of oral cholera vaccines in urban Bangladesh: A disease modeling and economic analysis. PLoS Negl Trop Dis. 2018; 12(10)

2. Khalil IA, Troeger C, Blacker BF, Rao PC, Brown A, Atherly DE, Brewer TG, Engmann CM, Houpt ER, Kang G, Kotloff KL, Levine MM, Luby SP, MacLennan CA, Pan WK, Pavlinac PB, Platts-Mills JA, Qadri F, Riddle MS, Ryan ET, Shoultz DA, Steele AD, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC Jr. Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016. Lancet Infect Dis. 2018 Sep 25.

3. Khan AI, Khan IA, Siddique SA, Rahman A, Islam MT, Bhuiya MAI, Saha NC, Biswas PK, Saha A, Chowdhury F, Qadri F. Feasibility, coverage and cost of oral cholera vaccination conducted by icddr,b using the existing national immunization service delivery mechanism in rural setting Keraniganj, Bangladesh. Hum Vaccin Immunother. 2018 Sep 27.

4. Houldcroft CJ, Beale MA, Sayeed MA, Qadri F, Dougan G, Mutreja A. Identification of novel adenovirus genotype 90 in children from Bangladesh. Microb Genom. 2018 Sep 24.

5. Islam MT, Clemens JD, Qadri F. Cholera Control and Prevention in Bangladesh: An Evaluation of the Situation and Solutions. J Infect Dis. 2018 Aug 28.

6. Islam MT, Sarker SK, Talukder S, Bhuyan GS, Rahat A, Islam NN, Mahmud H, Hossain MA, Muraduzzaman AKM, Rahman J, Qadri SK, Shahidullah M, Mannan MA, Tahura S,

Hussain M, Saha N, Akhter S, Nahar N, Begum F, Shirin T, Akhteruzzaman S, Qadri SS, Qadri F, Mannoor K. BMC Genet. 2018;19(1):58.

7. Impaired acylcarnitine profile in transfusion-dependent beta-thalassemia major patients in Bangladesh. Kumar Sarker S, Islam MT, Sarower Bhuyan G, Sultana N, Begum MN, Al Mahmud-Un-Nabi M, Al Noman Howladar MA, Farhana Dipta T, Muraduzzaman AKM, Kashfi Qadri S, Shirin T, Sadiya S, Hussain M, Ahmed Khan W, Akhteruzzaman S, Saleheen Qadri S, Qadri F, Mannoor K. J Adv Res. 2018; 12:55-66.

8. Andrews JR, Khanam F, Rahman N, Hossain M, Bogoch II, Vaidya K, Kelly M, Calderwood SB, Bhuiyan TR, Ryan ET, Qadri F, Charles RC. Plasma IgA responses against two Salmonella Typhi antigens identify patients with typhoid fever. Clin Infect Dis. 2018 Jul 18.

9. Baker-Austin C, Oliver JD, Alam M, Ali A, Waldor MK, Qadri F, Martinez-Urtaza J. Vibrio spp. infections.Nat Rev Dis Primers. 2018; 4(1):8.

10. Domman D, Chowdhury F, Khan AI, Dorman MJ, Mutreja A, Uddin MI, Paul A, Begum YA, Charles RC, Calderwood SB, Bhuiyan TR, Harris JB, LaRocque RC, Ryan ET, Qadri F, Thomson NR. Defining endemic cholera at three levels of spatiotemporal resolution within Bangladesh. Nat Genet. 2018; 50(7): 951-955.

11. Qadri F, Azad AK, Flora MS, Khan AI, Islam MT, Nair GB, Singh PK, Clemens JD., Emergency deployment of oral cholera vaccine for the Rohingya in Bangladesh. Lancet. 2018; 391(10133):1877-1879.

12. Saha A, Hayen A, Ali M, Rosewell A, MacIntyre CR, Clemens JD, Qadri F. Socioeconomic drivers of vaccine uptake: An analysis of the data of a geographically defined cluster randomized cholera vaccine trial in Bangladesh.Vaccine. 2018: S0264-410X (18) 30604-2.

13. Aktar A, Rahman MA, Afrin S, Akter A, Uddin T, Yasmin T, Sami MIN, Dash P, Jahan SR, Chowdhury F, Khan AI, LaRocque RC, Charles RC, Bhuiyan TR, Mandlik A, Kelly M, Kováč P, Xu P, Calderwood SB, Harris JB, Qadri F, Ryan ET. Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh. PLoS Negl Trop Dis. 2018; 12(4).

14. Midani FS, Weil AA, Chowdhury F, Begum YA, Khan AI, Debela MD, Durand HK, Reese AT, Nimmagadda SN, Silverman JD, Ellis CN, Ryan ET, Calderwood SB, Harris JB, Qadri F, David LA, LaRocque RC. Human Gut Microbiota Predicts Susceptibility to Vibrio cholerae Infection. J Infect Dis. 2018 Apr 12.

15. Mottram L, Wiklund G, Larson G, Qadri F, Svennerholm AM. Author Correction: FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in Bangladeshis. Sci Rep. 2018; 8(1):6058.

16. Islam K, Hossain M, Kelly M, Mayo Smith LM, Charles RC, Bhuiyan TR, Kováč P, Xu P, LaRocque RC, Calderwood SB, Simon JK, Chen WH, Haney D, Lock M, Lyon CE, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Harris JB, Qadri F, Ryan ET. Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera

vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers. PLoS Negl Trop Dis. 2018;12(4)

17. Qadri F, Ali M, Lynch J, Chowdhury F, Khan AI, Wierzba TF, Excler JL, Saha A, Islam MT, Begum YA, Bhuiyan TR, Khanam F, Chowdhury MI, Khan IA, Kabir A, Riaz BK, Akter A, Khan A, Asaduzzaman M, Kim DR, Siddik AU, Saha NC, Cravioto A, Singh AP, Clemens JD. Efficacy of a single-dose regimen of inactivated whole-cell oral cholera vaccine: results from 2 years of follow-up of a randomised trial. Lancet Infect Dis. 2018.

18. Sayeed MA, Islam K, Hossain M, Akter NJ, Alam MN, Sultana N, Khanam F, Kelly M, Charles RC, Kováč P, Xu P, Andrews JR, Calderwood SB, Amin J, Ryan ET, Qadri F. Development of a new dipstick (Cholkit) for rapid detection of Vibrio cholerae O1 in acute watery diarrheal stools. PLoS Negl Trop Dis. 2018; 12(3).

19. Begum YA, Rydberg HA, Thorell K, Kwak YK, Sun L, Joffré E, Qadri F, Sjöling. In Situ Analyses Directly in Diarrheal Stool Reveal Large Variations in Bacterial Load and Active Toxin Expression of Enterotoxigenic Escherichiacoli and Vibrio cholerae. mSphere. 2018; 3(1).

20. Lee B, Carmolli M, Dickson DM, Colgate ER, Diehl SA, Uddin MI, Islam S, Hossain M, Rafique TA, Bhuiyan TR, Alam M, Nayak U, Mychaleckyj JC, McNeal MM, Petri WA Jr., Qadri F, Haque R, Kirkpatrick BD. Rotavirus-specific IgA Responses Are Impaired and Serve as a Sub-Optimal Correlate of Protection among Infants in Bangladesh. Clin Infect Dis. 2018 Jan 31.

21. Lee B, Dickson DM, deCamp AC, Colgate ER, Diehl SA, Uddin MI, Sharmin S, Islam S, Bhuiyan TR, Alam M, Nayak U, Mychaleckyj JC, Taniuchi M, Petri WA Jr., Haque R, Qadri F, Kirkpatrick BD. Histoblood Group Antigen Phenotype Determines Susceptibility to Genotype-specific Rotavirus Infections and Impacts Measures of Rotavirus Vaccine Efficacy. J Infect Dis. 2018 Jan 30.

22. Levade I, Terrat Y, Leducq JB, Weil AA, Mayo-Smith LM, Chowdhury F, Khan AI, Boncy J, Buteau J, Ivers LC, Ryan ET, Charles RC, Calderwood SB, Qadri F, Harris JB, LaRocque RC, Shapiro BJ. Microb Genom. 2017; 3(12).

23. Islam MT, Sarkar SK, Sultana N, Begum MN, Bhuyan GS, Talukder S, Muraduzzaman AKM, Alauddin M, Islam MS, Biswas PP, Biswas A, Qadri SK, Shirin T, Banu B, Sadya S, Hussain M, Sarwardi G, Khan WA, Mannan MA, Shekhar HU, Chowdhury EK, Sajib AA, Akhteruzzaman S, Qadri SS, Qadri F, Mannoor K. BMC Genet. 2018; 19(1):1.

24. Bourque DL, Bhuiyan TR, Genereux DP, Rashu R, Ellis CN, Chowdhury F, Khan AI, Haq Alam N, Lazina Hossain AP, Mayo-Smith LM, Charles RC, Weil AA, LaRocque RC, Calderwood SB, Ryan ET, Karlsson EK, Qadri F, Harris JB. Analysis of the Human Mucosal Response to Cholera Reveals Sustained Activation of Innate Immune Signaling Pathways. Infect Immun. 2017; 13:.00594-17.

25. Park K, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H. Nano-Magnetic System For Rapid Diagnosis Of Acute Infection. ACS Nano. 2017; 11(11):11425-11432.

26. Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Harris JB, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F. Assessing antigen specific HLA-DR+ antibody secreting cell (DR+ASC) responses in whole blood in enteric infections using an ELISPOT technique. Microbes Infect. 2017; S1286-4579(17)30180-6.

27. Qadri F, Islam T, Clemens JD. Cholera in Yemen - An Old Foe Rearing Its Ugly Head N Engl J Med. 2017; 377(21):2005-2007.

28. Najnin N, Leder K, Qadri F, Forbes A, Unicomb L, Winch PJ, Ram PK, Leontsini E, Nizame FA, Arman S, Begum F, Biswas SK, Clemens JD, Ali M, Cravioto A, Luby SP. Impact of adding hand-washing and water disinfection promotion to oral cholera vaccination on diarrhoea-associated hospitalization in Dhaka, Bangladesh: evidence from a cluster randomized control trial. Int J Epidemiol. 2017; 46(6):2056-2066.

29. Mottram L, Wiklund G, Larson G, Qadri F, Svennerholm AM. FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in Bangladeshis. Sci Rep. 2017; 7(1):10649.

30. Khan AI, Islam MT, Qadri F. Safety of oral cholera vaccines during pregnancy in developing countries. Hum Vaccin Immunother. 2017; 13(10):2245-2246.

31. Meiring JE, Gibani M; TyVAC Consortium Meeting Group. The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26–27 October 2016, Oxford, UK. Vaccine. 2017; 35(38):5081-5088.

32. Saha A, Hayen A, Ali M, Rosewell A, Clemens JD, Raina MacIntyre C, Qadri F. Socioeconomic risk factors for cholera in different transmission settings: An analysis of the data of a cluster randomized trial in Bangladesh. Vaccine. 2017: S0264-410X (17)30917-9.

33. Bi Q, Ferreras E, Pezzoli L, Legros D, Ivers LC, Date K, Qadri F, Digilio L, Sack DA, Ali M, Lessler J, Luquero FJ, Azman AS; Oral Cholera Vaccine Working Group of The Global Task Force on Cholera Control. Lancet Infect Dis. 2017: S1473-3099(17)30359-6.

34. Darton TC, Meiring JE, Tonks S, Khan MA, Khanam F, Shakya M, Thindwa D, Baker S, Basnyat B, Clemens JD, Dougan G, Dolecek C, Dunstan SJ, Gordon MA, Heyderman RS, Holt KE, Pitzer VE, Qadri F, Zaman K, Pollard AJ; STRATAA Study Consortium. The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys. BMJ Open. 2017;7(6):

35. Sahl JW, Sistrunk JR, Baby NI, Begum Y, Luo Q, Sheikh A, Qadri F, Fleckenstein JM, Rasko DA. Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology. Sci Rep. 2017; 7(1):3402.

36. Charles RC, Nakajima R, Liang L, Jasinskas A, Berger A, Leung DT, Kelly M, Xu P, Kovác P, Giffen SR, Harbison JD, Chowdhury F, Khan AI, Calderwood SB, Bhuiyan TR, Harris JB, Felgner PL, Qadri F, Ryan ET. The plasma and mucosal IgM, IgA, and IgG responses to the Vibrio cholerae O1 protein immunome in adults with cholera in Bangladesh. J Infect Dis. 2017; 216(1):125-134.

37. Sheikh A, Rashu R, Begum YA, Kuhlman FM, Ciorba MA, Hultgren SJ, Qadri F, Fleckenstein JM. Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions. PLoS Negl Trop Dis. 2017; 11(5).

38. Andrews JR, Leung DT, Ahmed S, Malek MA, Ahmed D, Begum Y, Qadri F, Ahmed T, Faruque ASG, Nelson EJ. Determinants of severe dehydration from diarrheal disease at hospital presentation: Evidence from 22 years of admissions in Bangladesh. PLoS Negl Trop Dis. 2017; 11(4).

39. Zaman K, Sack DA, Neuzil KM, Yunus M, Moulton LH, Sugimoto JD, Fleming JA, Hossain I, Arifeen SE, Azim T, Rahman M, Lewis KDC, Feller AJ, Qadri F, Halloran ME, Cravioto A, Victor JC. Effectiveness of a live oral human rotavirus vaccine after programmatic introduction in Bangladesh: A cluster-randomized trial. PLoS Med. 2017; 14(4).

40. Bhuyan GS, Hossain MA, Sarker SK, Rahat A, Islam MT, Haque TN, Begum N, Qadri SK, Muraduzzaman AK, Islam NN, Islam MS, Sultana N, Jony MH, Khanam F, Mowla G, Matin A, Begum F, Shirin T, Ahmed D, Saha N, Qadri F, Mannoor K. Bacterial and viral pathogen spectra of acute respiratory infections in under-5 children in hospital settings in Dhaka city. PLoS One. 2017; 12(3).

41. Bitar A, De R, Melgar S, Aung KM, Rahman A, Qadri F, Wai SN, Shirin T, Hammarström ML. Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. PLoS One. 2017; 12(3).

42. Clemens JD, Nair GB, Ahmed T, Qadri F, Holmgren J. Cholera, Lancet. 2017: S0140-6736(17)30559-7.

43. Khan AI, Ali M, Chowdhury F, Saha A, Khan IA, Khan A, Akter A, Asaduzzaman M, Islam MT, Kabir A, You YA, Saha NC, Cravioto A, Clemens JD, Qadri F., Safety of the oral cholera vaccine in pregnancy: retrospective findings from a subgroup following mass vaccination campaign in Dhaka, Bangladesh. Vaccine. 2017; 35(11):1538-1543.

44. Xu P, Kelly M, Vann WF, Qadri F, Ryan ET, Kovac P. Conjugate Vaccines from Bacterial Antigens by Squaric Acid Chemistry: A Closer Look. Chembiochem. 2017; 18(8):799-815.

45. Kauffman RC, Bhuiyan TR, Nakajima R, Mayo-Smith LM, Rashu R, Hoq MR, Chowdhury F, Khan AI, Rahman A, Bhaumik SK, Harris L, O'Neal JT, Trost JF, Alam NH, Jasinskas A, Dotsey E, Kelly M, Charles RC, Xu P, Kováč P, Calderwood SB, Ryan ET, Felgner PL,

Qadri F, Wrammert J, Harris JB. Single-Cell Analysis of the Plasmablast Response to Vibrio cholerae Demonstrates Expansion of Cross-Reactive Memory B Cells. MBio. 2016; 7(6).

46. Al-Mamun MM, Sarker SK, Qadri SK, Shirin T, Mohammad QD, LaRocque R, Karlsson EK, Saha N, Asaduzzaman M, Qadri F, Mannoor MK. Examination of Huntington's disease with atypical clinical features in a Bangladeshi family tree. Clin Case Rep. 2016; 4(12):1191-1194.

47. Akhtar M, Qadri F, Bhuiyan TR, Akter S, Rafique TA, Khan A, Islam LN, Saha A, Svennerholm AM, Lundgren A. Kinetics of antibody-secreting cell and fecal IgA responses after oral cholera vaccination in different age groups in a cholera endemic country.Vaccine. 2016; (16)31117-3.

48. Sarker SK, Islam MT, Eckhoff G, Hossain MA, Qadri SK, Muraduzzaman AK, Bhuyan GS, Shahidullah M, Mannan MA, Tahura S, Hussain M, Akhter S, Nahar N, Shirin T, Qadri F, Mannoor K. Molecular Analysis of Glucose-6-Phosphate Dehydrogenase Gene Mutations in Bangladeshi Individuals. PLoS One. 2016; 11(11).

49. Uddin MI, Islam S, Nishat NS, Hossain M, Rafique TA, Rashu R, Hoq MR, Zhang Y, Saha A, Harris JB, Calderwood SB, Bhuiyan TR, Ryan ET, Leung DT, Qadri F. Biomarkers of Environmental Enteropathy are Positively Associated with Immune Responses to an Oral Cholera Vaccine in Bangladeshi Children. PLoS Negl Trop Dis. 2016; 10(11).

50. Saha A, Rosewell A, Hayen A, MacIntyre CR, Qadri F. Improving immunization approaches to cholera. Expert Rev Vaccines. 2017; 16(3):235-248.

51. Gellin BG, Qadri F. Preparing for the unpredictable: The continuing need for pandemic influenza preparedness. Vaccine. 2016; 34(45): 5391-5392.

52. Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC. A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever. Sci Rep. 2016; 6: 32878.

53. Verkerke H, Sobuz S, Ma JZ, Petri SE, Reichman D, Qadri F, Rahman M, Haque R, Petri WA Jr. Malnutrition is associated with protection from rotavirus diarrhea: evidence from a longitudinal birth cohort study in Bangladesh. J Clin Microbiol. 2016; 54(10): 2568-74.

54. Begum YA, Talukder KA, Azmi IJ, Shahnaij M, Sheikh A, Sharmin S, Svennerholm AM, Qadri F. Resistance Pattern and Molecular Characterization of Enterotoxigenic Escherichia coli (ETEC) Strains Isolated in Bangladesh. PLoS One. 2016; 11(7).

55. Matias WR, Falkard B, Charles RC, Mayo-Smith LM, Teng JE, Xu P, Kováč P, Ryan ET, Qadri F, Franke MF, Ivers LC, Harris JB. Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults. PLoS Negl Trop Dis. 2016; 10(6).

56. Colgate ER, Haque R, Dickson DM, Carmolli MP, Mychaleckyj JC, Nayak U, Qadri F, Alam M, Walsh MC, Diehl SA, Zaman K, Petri WA Jr, Kirkpatrick BD. A Randomized Controlled Trial with Delayed Dosing of Oral Rotavirus Vaccine Demonstrates Decreased

Risk of Rotavirus Gastroenteritis Associated with Serum Zinc. Clin Infect Dis. 2016; 63(5):634-41.

57. Ahmad SM, Alam J, Afsar NA, Huda N, Kabir Y, Qadri F, Raqib R, Stephensen CB. Comparisons of the effect of naturally acquired maternal pertussis antibodies and antenatal vaccination induced maternal tetanus antibodies on infant's antibody secreting lymphocyte responses and circulating plasma antibody levels. Hum Vaccin Immunother. 2016; 12(4): 886-93.

58. Qadri F, Wierzba TF, Ali M, Chowdhury F, Khan AI, Saha A, Khan IA, Asaduzzaman M, Akter A, Khan A, Begum YA, Bhuiyan TR, Khanam F, Chowdhury MI, Islam T, Chowdhury AI, Rahman A, Siddique SA, You YA, Kim DR, Siddik AU, Saha NC, Kabir A, Cravioto A, Desai SN, Singh AP, Clemens JD. Efficacy of a Single-Dose, Inactivated Oral Cholera Vaccine in Bangladesh.N Engl J Med. 2016; 374(18):1723-32.

59. Islam K, Sayeed MA, Hossen E, Khanam F, Charles RC, Andrews J, Ryan ET, Qadri F. Comparison of the Performance of the TPTest, Tubex, Typhidot and Widal Immunodiagnostic Assays and Blood Cultures in Detecting Patients with Typhoid Fever in Bangladesh, Including Using a Bayesian Latent Class Modeling Approach. PLoS Negl Trop Dis. 2016; 10(4).

60. Aktar A, Rahman MA, Afrin S, Faruk MO, Uddin T, Akter A, Sami MI, Yasmin T, Chowdhury F, Khan AI, Leung DT, LaRocque RC, Charles RC, Bhuiyan TR, Mandlik A, Bufano MK, Kováč P, Xu P, Calderwood SB, Harris JB, Qadri F, Ryan ET. O-specific polysaccharide (OSP)-specific memory B cell responses in young children, older children and adults infected with Vibrio cholerae O1 Ogawa in Bangladesh. Clin Vaccine Immunol. 2016; 23(5):427-35.

61. Sarker SA, Sultana S, Reuteler G, Moine D, Descombes P, Charton F, Bourdin G, McCallin S, Ngom-Bru C, Neville T, Akter M, Huq S, Qadri F, Talukdar K, Kassam M, Delley M, Loiseau C, Deng Y, El Aidy S, Berger B, Brüssow H. Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh. EBioMedicine. 2016; 4:124-37.

62. Khan IH, Sayeed MA, Sultana N, Islam K, Amin J, Faruk MO, Khan U, Khanam F, Ryan ET, Qadri F. Development of a simple, peripheral blood-based lateral-flow dipstick assay for accurate detection of patients with enteric fever. Clin Vaccine Immunol. 2016: 00690 -15.

63. Hatzios SK, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, Clark L, Bachovchin DA, Qadri F, Ryan ET, Davis BM, Weerapana E, Waldor MK. Chemoproteomic profiling of host and pathogen enzymes active in cholera. Nat Chem Biol. 2016; 12(6):466.

64. Saha A, Khan A, Salma U, Jahan N, Bhuiyan TR, Chowdhury F, Khan AI, Khanam F, Muruganandham S, Reddy Kandukuri S, Singh Dhingra M, Clemens JD, Cravioto A, Qadri F. The oral cholera vaccine Shanchol™ when stored at elevated temperatures maintains the safety and immunogenicity profile in Bangladeshi participants. Vaccine. 2016; 34(13):1551-8.

65. Paul RC, Faruque AS, Alam M, Iqbal A, Zaman K, Islam N, Sobhan A, DAS SK, Malek MA, Qadri F, Cravioto A, Luby SP. Incidence of severe diarrhoea due to Vibrio cholerae in

the catchment area of six surveillance hospitals in Bangladesh. Epidemiol Infect. 2016; 144(5): 927-39

66. Chowdhury F, Mather AE, Begum YA, Asaduzzaman M, Baby N, Sharmin S, Biswas R, Ikhtear Uddin M, LaRocque RC, Harris JB, Calderwood SB, Ryan ET, Clemens JD, Thomson NR, Qadri F. Vibrio cholerae Serogroup O139: Isolation from Cholera Patients and Asymptomatic Household Family Members in Bangladesh between 2013 and 2014. PLoS Negl Trop Dis. 2015; 9(11).

67. Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Dey A, Harris JB, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F. Enumeration of gut-homing β7-positive, pathogen-specific antibody secreting cells in whole blood in enterotoxigenic Escherichia coli and Vibrio cholerae-infected patients using an ELISPOT technique. Clin Vaccine Immunol. 2015; 23(1):27-36.

68. Clemens JD, Qadri F. Cholera in Bangladesh. Weekly epidemiological record, WHO. No 40, 2015.90: 517-544.

69. Chowdhury F, Kuchta A, Khan AI, Faruque AS, Calderwood SB, Ryan ET, Qadri F. The increased severity in patients presenting to hospital with diarrhea in Dhaka, Bangladesh since the emergence of the hybrid strain of Vibrio cholerae O1 is not unique to cholera patients. Int J Infect Dis. 2015; 40:9-14.

70. Paul RC, Faruque AS, Alam M, Iqbal A, Zaman K, Islam N, Sobhan A, DAS SK, Malek MA, Qadri F, Cravioto A, Luby SP. Incidence of severe diarrhoea due to Vibrio cholerae in the catchment area of six surveillance hospitals in Bangladesh. Epidemiol Infect. 2016; 144(5): 927-39.

71. Shahunja KM, Leung DT, Ahmed T, Bardhan PK, Ahmed D, Qadri F, Ryan ET, Chisti MJ. Factors Associated with Non-typhoidal Salmonella Bacteremia versus Typhoidal Salmonella Bacteremia in Patients Presenting for Care in an Urban Diarrheal Disease Hospital in Bangladesh. PLoS Negl Trop Dis. 2015; 9(9).

72. Khan AI, Chowdhury F, Leung DT, Larocque RC, Harris JB, Ryan ET, Calderwood SB, Qadri F. Cholera in pregnancy: Clinical and immunological aspects. Int J Infect Dis. 2015; 39: 20-24.

73. Sarker AR, Islam Z, Khan IA, Saha A, Chowdhury F, Khan AI, Cravioto A, Clemens JD, Qadri F, Khan JA. Estimating the cost of cholera-vaccine delivery from the societal point of view: A case of introduction of cholera vaccine in Bangladesh. Vaccine. 2015; 33(38): 4916-21.

74. Qadri F,  Ali M, Chowdhury F, Khan AI, Saha A, Khan IA, Begum YA, Bhuiyan TR, Chowdhury MI, Uddin MJ, Khan JAM, Chowdhury AI, Rahman A, Siddique SA, Asaduzzaman M, Akter A, Khan MA, You YA, Siddik AU, Saha NC, Kabir A, Riaz BK, Biswas SK, Begum F, Unicomb L, Luby SP, Cravioto A, Clemens JD. Feasibility and effectiveness of the oral cholera vaccine, in an urban “cholera-endemic” setting in Bangladesh: a cluster-randomised non-blinded trial. Lancet.2015; 386(10001):1362-71.

75. Sayeed MA, Bufano MK, Xu P, Eckhoff G, Charles RC, Alam MM, Sultana T, Rashu MR, Berger A, Gonzalez-Escobedo G, Mandlik A, Bhuiyan TR, Leung DT, LaRocque RC, Harris JB, Calderwood SB, Qadri F, Vann WF, Kováč P, Ryan ET. A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP: rTTHc) Induces Serum, Memory and

Lamina Proprial Responses against OSP and Is Protective in Mice. PLoS Negl Trop Dis. 2015; 9(7).

76. Leung DT, Das SK, Malek MA, Qadri F, Faruque AS, Chisti MJ, Ryan ET. Concurrent Pneumonia in Children Under 5 Years of Age Presenting to a Diarrheal Hospital in Dhaka, Bangladesh. Am J Trop Med Hyg. 2015; 93(4):831-5.

77. Chowdhury F, Khan IA, Patel S, Siddiq AU, Saha NC, Khan AI, Saha A, Cravioto A, Clemens J, Qadri F, Ali M. Diarrheal Illness and Healthcare Seeking Behavior among a Population at High Risk for Diarrhea in Dhaka, Bangladesh. PLoS One. 2015; 10(6): e0130105.

78. Sahl JW, Sistrunk JR, Fraser CM, Hine E, Baby N, Begum Y, Luo Q, Sheikh A, Qadri F, Fleckenstein JM, Rasko DA. Examination of the Enterotoxigenic Escherichia coli Population Structure during Human Infection. MBio. 2015; 6(3).

79. Falkard B, Uddin T, Arifur Rahman M, Franke MF, Aktar A, Uddin MI, Bhuiyan TR, Leung DT, Charles RC, Larocque RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Plasma Leptin Levels in Children Hospitalized with Cholera in Bangladesh. Am J Trop Med Hyg. 2015; 93(2):244-9.

80. David LA, Weil A, Ryan ET, Calderwood SB, Harris JB, Chowdhury F, Begum Y, Qadri F, LaRocque RC, Turnbaugh PJ. Gut microbial succession follows acute secretory diarrhea in humans. MBio. 2015; 6(3):e00381-15.

81. Liu F, Yang X, Wang Z, Nicklasson M, Qadri F, Yi Y, Zhu Y, Lv N, Li J, Zhang R, Guo H, Zhu B, Sjöling Å, Hu Y. Draft genomes of four enterotoxigenic Escherichia coli (ETEC) clinical isolates from China and Bangladesh. Gut Pathog. 2015; 7:10.

82. Khanam F, Sayeed MA, Choudhury FK, Sheikh A, Ahmed D, Goswami D, Hossain ML, Brooks A, Calderwood SB, Charles RC, Cravioto A, Ryan ET, Qadri F. Typhoid Fever in young children in bangladesh: clinical findings, antibiotic susceptibility pattern and immune responses. PLoS Negl Trop Dis. 2015; 9(4).

83. Ivers LC, Charles RC, Hilaire IJ, Mayo-Smith LM, Teng JE, Jerome JG, Rychert J, LaRocque RC, Xu P, Kováč P, Ryan ET, Qadri F, Almazor CP, Franke MF, Harris JB. Immunogenicity of the bivalent oral cholera vaccine Shanchol in Haitian adults with HIV infection. J Infect Dis. 2015; 212(5):779-83.

84. Kirkpatrick BD, Colgate ER, Mychaleckyj JC, Haque R, Dickson DM, Carmolli MP, Nayak U, Taniuchi M, Naylor C, Qadri F, Ma JZ, Alam M, Walsh MC, Diehl SA; the PROVIDE Study Teams, Petri WA Jr. The "Performance of Rotavirus and Oral Polio Vaccines in Developing Countries" (PROVIDE) Study: Description of Methods of an Interventional Study Designed to Explore Complex Biologic Problems. Am J Trop Med Hyg. 2015; 92(4):744-51

85. Luo Q, Qadri F, Kansal R, Rasko DA, Sheikh A, Fleckenstein JM. Conservation and Immunogenicity of Novel Antigens in Diverse Isolates of Enterotoxigenic Escherichia coli. Infection and immunity. 2015; 83:1089-1103.

86. Ellis CN, LaRocque RC, Uddin T, Krastins B, Mayo-Smith L, Sarracino D, Karlsson E, Rahman A, Shirin T, Bhuiyan TR, Chowdhury F, Kahn AI, Ryan ET, Calderwood SB, Qadri F, Harris JB. Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera. Infect Immun. 2015; 83(3):1089-103.

87. Sugimoto JD, Koepke AA, Kenah EE, Halloran ME, Chowdhury F, Khan AI, LaRocque RC, Yang Y, Ryan ET, Qadri F, Calderwood SB, Harris JB, Longini IM Jr. Household Transmission of Vibrio cholerae in Bangladesh. PLoS Negl Trop Dis. 2014; 8(11).

88. Rychert J, Creely D, Mayo-Smith LM, Calderwood SB, Ivers LC, Ryan ET, Boncy J, Qadri F, Ahmed D, Ferraro MJ, Harris JB. Evaluation of MALDI-TOF Mass Spectrometry for Identification of Vibrio cholerae. J Clin Microbiol. 2015; 53(1):329-31.

89. Ahmad SM, Raqib R, Qadri F, Stephensen CB. The effect of newborn vitamin A supplementation on infant immune functions: Trial design, interventions, and baseline data. Contemp Clin Trials. 2014; 39(2):269-79.

90. Uddin MJ, Wahed T, Saha NC, Kaukab SS, Khan IA, Khan AI, Saha A, Chowdhury F, Clemens JD, Qadri F. Coverage and acceptability of cholera vaccine among high-risk population of urban Dhaka, Bangladesh. Vaccine. 2014; 32(43):5690-5.

91. Leung DT, Bhuiyan TR, Nishat NS, Hoq MR, Aktar A, Rahman MA, Uddin T, Khan AI, Chowdhury F, Charles RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Circulating Mucosal Associated Invariant T Cells Are Activated in Vibrio cholerae O1 Infection and Associated with Lipopolysaccharide Antibody Responses. PLoS Negl Trop Dis. 2014; 8(8).

92. Weil AA, Begum Y, Chowdhury F, Khan AI, Leung DT, LaRocque RC, Charles RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Bacterial Shedding in Household Contacts of Cholera Patients in Dhaka, Bangladesh. Am J Trop Med Hyg. 2014; 91(4):738-42.

93. Begum YA, Baby NI, Faruque AS, Jahan N, Cravioto A, Svennerholm AM, Qadri F. Shift in Phenotypic Characteristics of Enterotoxigenic Escherichia coli (ETEC) Isolated from Diarrheal Patients in Bangladesh. PLoS Negl Trop Dis. 2014: 17; 8(7).

94. Huda MN, Lewis Z, Kalanetra KM, Rashid M, Ahmad SM, Raqib R, Qadri F, Underwood MA, Mills DA, Stephensen CB. Stool Microbiota and Vaccine Responses of Infants. Pediatrics. 2014;134(2):362-72.

95. Sheikh A, Lou Q, Roy K, Shabaan S, Kumar P, Qadri F, Fleckenstein, Contribution of the highly conserved EaeH surface protein to enterotoxigenic Escherichia coli pathogenesis. JM. Infect Immun. 2014; 82(9):3657-66.

96. Khan MK, Zaman S, Chakraborty S, Chakravorty R, Alam MM, Bhuiyan TR, Rahman MJ, Fernández C, Qadri F, Seraj ZI. In silico predicted mycobacterial epitope elicits in vitro T-cell responses, Mol Immunol. 2014; 61(1):16-22.

97. Bhuiyan TR, Choudhury FK, Khanam F, Saha A, Sayeed MA, Salma U, Qadri F, Lundgren A, Svennerholm AM, Sack DA. Response on letter by Arya et al.: "Evaluation of immune responses to an oral typhoid vaccine, Ty21a, in children from 2 to 5 years of age in Bangladesh." Vaccine. 2014; 32(32): 4014.

98. Charles RC, Hilaire IJ, Mayo-Smith LM, Teng JE, Jerome JG, Franke MF, Saha A, Yu Y, Kováč P, Calderwood SB, Ryan ET, Larocque RC, Almazor CP, Qadri F, Ivers LC, Harris JB. Immunogenicity of a killed bivalent (o1 and o139) whole cell oral cholera vaccine, shanchol, in haiti. PLoS Negl Trop Dis. 2014; 8(5).

99. Alam MM, Aktar A, Afrin S, Rahman MA, Aktar S, Uddin T, Rahman MA, Mahbuba DA, Chowdhury F, Khan AI, Bhuiyan TR, Begum YA, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F. Antigen-Specific Memory B-cell Responses to Enterotoxigenic Escherichia coli Infection in Bangladeshi Adults. PLoS Negl Trop Dis. 2014; 8(4).

100. Bhuiyan TR, Islam MM, Uddin T, Chowdhury MI, Janzon A, Adamsson J, Lundin SB, Qadri F, Lundgren A. Th1 and Th17 Responses to Helicobacter pylori in Bangladeshi Infants, Children and Adults. PLoS One. 2014; 9(4).

101. Fleckenstein J, Sheikh A, Qadri F. Novel antigens for enterotoxigenic Escherichia coli vaccines. Expert Rev Vaccines. 2014; 13(5):631-9.

102. Uddin T, Aktar A, Xu P, Johnson RA, Rahman MA, Leung DT, Afrin S, Akter A, Alam MM, Rahman A, Chowdhury F, Khan AI, Bhuiyan TR, Bufano MK, Rashu R, Yu Y, Wu-Freeman Y, Harris JB, LaRocque RC, Charles RC, Kováč P, Calderwood SB, Ryan ET, Qadri F. Immune Responses to O-Specific Polysaccharide and Lipopolysaccharide of Vibrio cholerae O1 Ogawa in Adult Bangladeshi Recipients of an Oral Killed Cholera Vaccine and Comparison to Responses in Patients with Cholera. Am J Trop Med Hyg. 2014; 90(5):873-81.

103. Bhuiyan TR, Choudhury FK, Khanam F, Saha A, Sayeed MA, Salma U, Lundgren A, Sack DA, Svennerholm AM, Qadri F. Cellular and Cytokine Responses to Salmonella enterica Serotype Typhi Proteins in Patients with Typhoid Fever in Bangladesh. Vaccine. 2014; 32(9):1055-60.

104. Charles RC, Liang L, Khanam F, Sayeed MA, Hung C, Leung DT, Baker S, Ludwig A, Harris JB, Larocque RC, Calderwood SB, Qadri F, Felgner PL, Ryan ET. Immunoproteomic Analysis of Antibody in Lymphocyte Supernatant in Patients with Typhoid Fever in Bangladesh. Clin Vaccine Immunol. 2014; 21(3):280-5.

105. DAS SK, Begum D, Ahmed S, Ferdous F, Farzana FD, Chisti MJ, Latham JR, Talukder KA, Rahman MM, Begum YA, Faruque AS, Malek MA, Qadri F, Ahmed T, Alam N. Geographical diversity in seasonality of major diarrhoeal pathogens in Bangladesh observed between 2010 and 2012. Epidemiol Infect. 2014; 142(12):2530-41.

106. Bourdin G, Navarro A, Sarker SA, Pittet AC, Qadri F, Sultana S, Cravioto A, Talukder KA, Reuteler G, Brüssow H. Coverage of diarrhoea-associated Escherichia coli isolates from different origins with two types of phage cocktails. Microb Biotechnol. 2014; 7(2):165-76.

107. Alam MM, Bufano MK, Xu P, Kalsy A, Yu Y, Freeman YW, Sultana T, Rashu MR, Desai I, Eckhoff G, Leung DT, Charles RC, Larocque RC, Harris JB, Clements JD, Calderwood SB, Qadri F, Vann WF, Kováč P, Ryan ET. Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide. PLoS Negl Trop Dis. 2014;8(2).

108. Bhuiyan TR, Choudhury FK, Khanam F, Saha A, Sayeed MA, Salma U, Lundgren A, Sack DA, Svennerholm AM, Qadri F. Evaluation of immune responses to an oral typhoid

vaccine, Ty21a, in children from 2 to 5 years of age in Bangladesh. Vaccine. 2014; 32(9):1055-60

109. Leung DT, Das SK, Malek MA, Qadri F, Faruque AS, Ryan ET. Impact of Ramadan on Clinical and Microbiologic Parameters of Patients Seen at a Diarrheal Hospital in Urban Dhaka, Bangladesh, 1996-2012. Am J Trop Med Hyg. 2014; 90(2):294-8.

110. Charles RC, Liang L, Khanam F, Sayeed MA, Hung C, Leung DT, Baker S, Ludwig A, Harris JB, Larocque RC, Calderwood SB, Qadri F, Felgner PL, Ryan ET. Immunoproteomic analysis of antibody-in-lymphocyte supernatant (ALS) in patients with typhoid fever in Bangladesh Clin Vaccine Immunol. 2014; 21(3):280-5.

111. Das SK, Ahmed S, Ferdous F, Farzana FD, Chisti MJ, Latham JR, Talukder KA, Rahman M, Begum YA, Qadri F, Faruque AS, Ahmed T. Etiological diversity of diarrhoeal disease in Bangladesh. J Infect Dev Ctries. 2013; 7(12): 900-9.

112. Saha A, Qadri F. Infection: Mass vaccination is feasible in response to cholera epidemics. Nat Rev Gastroenterol Hepatol. 2013; 10(12):700-1.

113. Sarker AR, Islam Z, Khan IA, Saha A, Chowdhury F, Khan AI, Qadri F, Khan JA. Cost of illness for cholera in a high risk urban area in Bangladesh: an analysis from household perspective. BMC Infect Dis. 2013; 13(1):518.

114. Khan IA, Saha A, Chowdhury F, Khan AI, Uddin MJ, Begum YA, Riaz BK, Islam S, Ali M, Luby SP, Clemens JD, Cravioto A, Qadri F. Coverage and cost of a large oral cholera vaccination program in a high-risk cholera endemic urban population in Dhaka, Bangladesh. Vaccine. 2013; 31(51):6058-64.

115. Khanam F, Sheikh A, Sayeed MA, Bhuiyan MS, Choudhury FK, Salma U, Pervin S, Sultana T, Ahmed D, Goswami D, Hossain ML, Mamun KZ, Charles RC, Brooks WA, Calderwood SB, Cravioto A, Ryan ET, Qadri F. Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood Lymphocytes in Patients in Dhaka, Bangladesh. PLoS Negl Trop Dis.2013; 7(7).

116. Rahman A, Rashu R, Bhuiyan TR, Chowdhury F, Khan AI, Islam K, Larocque RC, Ryan ET, Wrammert J, Calderwood SB, Qadri F, Harris JB. Antibody secreting cell responses after Vibrio cholerae O1 infection and oral cholera vaccination in adults in Bangladesh. Clin Vaccine Immunol. 2013; 20(10):1592-8.

117. Charles RC, Sultana T, Alam MM, Yu Y, Wu-Freeman Y, Bufano MK, Rollins SM, Tsai L, Harris JB, Larocque RC, Leung DT, Brooks WA, Nga TV, Dongol S, Basnyat B, Calderwood SB, Farrar J, Khanam F, Gunn JS, Qadri F, Baker S, Ryan ET. Identification of Immunogenic Salmonella enterica Serotype Typhi Antigens Expressed in Chronic Biliary Carriers of S. Typhi in Kathmandu, Nepal. PLoS Negl Trop Dis. 2013; 7(8).

118. Alam MM, Leung DT, Akhtar M, Nazim M, Akter S, Uddin T, Khanam F, Mahbuba DA, Ahmad SM, Bhuiyan TR, Calderwood SB, Ryan ET, Qadri F. Antibody avidity following

administration of an oral killed cholera vaccine: comparing humoral immune responses in Bangladeshi children with those in adults. Clin Vaccine Immunol. 2013; 20(10):1541-8.

119. Ahmed T, Bhuiyan TR, Zaman K, Sinclair D, Qadri F. Vaccines for preventing enterotoxigenic Escherichia coli (ETEC) diarrhoea. Cochrane Database Syst Rev. 2013; 7:CD009029.

120. Karlsson EK, Harris JB, Tabrizi S, Rahman A, Shlyakhter I, Patterson N, O'Dushlaine C, Schaffner SF, Gupta S, Chowdhury F, Sheikh A, Shin OS, Ellis C, Becker CE, Stuart LM, Calderwood SB, Ryan ET, Qadri F, Sabeti PC, Larocque RC. Natural selection in a bangladeshi population from the cholera-endemic ganges river delta. Sci Transl Med. 2013; 5(192):192ra86.

121. Leung DT, Uddin T, Xu P, Aktar A, Johnson RA, Rahman MA, Alam MM, Bufano MK, Eckhoff G, Wu-Freeman Y, Yu Y, Sultana T, Khanam F, Saha A, Chowdhury F, Khan AI, Charles RC, Larocque RC, Harris JB, Calderwood SB, Kovác P, Qadri F, Ryan ET. Immune responses to the O-specific polysaccharide antigen in children receiving a killed oral cholera vaccine compared to responses following natural cholera infection in Bangladesh. Clin Vaccine Immunol. 2013; 20(6):780-8.

122. Wahed T, Kaukab SS, Saha NC, Khan IA, Khanam F, Chowdhury F, Saha A, Khan AI, Siddik AU, Cravioto A, Qadri F, Uddin J. Knowledge of, attitudes toward, and preventive practices relating to cholera and oral cholera vaccine among urban high-risk groups: findings of a cross-sectional study in Dhaka, Bangladesh. BMC Public Health. 2013; 13(1):242.

123. Alam MM, Tsai LL, Rollins SM, Sheikh A, Khanam F, Bufano MK, Yu Y, Wu-Freeman Y, Kalsy A, Sultana T, Sayeed MA, Jahan N, Larocque RC, Harris JB, Leung DT, Brooks WA, Calderwood SB, Charles RC, Qadri F, Ryan ET. Identification of in vivo-induced bacterial proteins during human infection with Salmonella enterica serotype Paratyphi A. J Clin Invest. 2013; 123(3):1343-7.

124. Leung DT, Das SK, Malek MA, Ahmed D, Khanam F, Qadri F, Faruque AS, Ryan ET. Non-Typhoidal Salmonella Gastroenteritis at a Diarrheal Hospital in Dhaka, Bangladesh, 1996-2011. Am J Trop Med Hyg. 2013; 88(4):661-9.

125. Ahmed D, Islam MS, Begum YA, Janzon A, Qadri F, Sjöling A. Presence of enterotoxigenic Escherichia coli in biofilms formed in water containers in poor households coincides with epidemic seasons in Dhaka. J Appl Microbiol. 2013; 114(4):1223-9.

126. Saha A, Chowdhury MI, Nazim M, Alam MM, Ahmed T, Hossain MB, Hore SK, Sultana GN, Svennerholm AM, Qadri F. Vaccine specific immune response to an inactivated oral cholera vaccine and EPI vaccines in a high and low arsenic area in Bangladeshi children. Vaccine. 2013 :1;31(4):647-52.

127. Qadri F, Bhuiyan TR, Sack DA, Svennerholm AM. Immune responses and protection in children in developing countries induced by oral vaccines. Vaccine. 2013: 31(3):452-60.

128. Alam MM, Arifuzzaman M, Ahmad SM, Hosen MI, Rahman MA, Rashu R, Sheikh A, Ryan ET, Calderwood SB, Qadri F. Study of avidity of antigen-specific antibody as a means

of understanding development of long-term immunological memory after Vibrio cholerae O1 infection. Clin Vaccine Immunol. 2013; 20(1):17-23.

129. Seed KD, Faruque SM, Mekalanos JJ, Calderwood SB, Qadri F, Camilli A. Phase Variable O Antigen Biosynthetic Genes Control Expression of the Major Protective Antigen and Bacteriophage Receptor in Vibrio cholerae O1. PLoS Pathog. 2012; 8(9).

130. Johnson RA, Uddin T, Aktar A, Mohasin M, Alam MM, Chowdhury F, Harris JB, Larocque RC, Bufano M, Yu Y, Wu Y, Leung DT, Sarracino D, Krastins B, Charles RC, Xu P, Kovác P, Calderwood SB, Qadri F, Ryan ET. Comparison of immune responses to the O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi adult patients with cholera. Clin Vaccine Immunol. 2012; 19(11):1712-21.

131. Weil AA, Chowdhury F, Khan AI, Leung DT, Uddin T, Begum YA, Saha NC, Charles RC, Larocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Frequency of Reexposure to Vibrio cholerae O1 Evaluated by Subsequent Vibriocidal Titer Rise after an Episode of Severe Cholera in a Highly Endemic Area in Bangladesh. Am J Trop Med Hyg. 2012; 87(5):921-926.

132. Sealfon R, Gire S, Ellis C, Calderwood S, Qadri F, Hensley L, Kellis M, Ryan ET, Larocque RC, Harris JB, Sabeti PC. High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic. BMC Genomics. 2012; 13:468.

133. Harris JB, LaRocque RC, Qadri F, Ryan ET, Calderwood SB. Cholera. Lancet. 2012; 379 (9835): 2466-76.

134. Arifuzzaman M, Rashu R, Leung DT, Hosen MI, Bhuiyan TR, Bhuiyan MS, Rahman MA, Khanam F, Saha A, Charles RC, Larocque RC, Weil AA, Clements JD, Holmes RK, Calderwood SB, Harris JB, Ryan ET, Qadri F. Antigen-specific memory T cell responses after vaccination with an oral killed cholera vaccine in Bangladeshi children and comparison with natural cholera. Clin Vaccine Immunol. 2012; 19(8):1304-11.

135. Nicklasson M, Sjöling A, von Mentzer A, Qadri F, Svennerholm AM. Expression of Colonization Factor CS5 of Enterotoxigenic Escherichia coli (ETEC) Is Enhanced In Vivo and by the Bile Component Na Glycocholate Hydrate. PLoS One. 2012; 7(4).

136. Patel SM, Rahman MA, Mohasin M, Riyadh MA, Leung DT, Alam MM, Chowdhury F, Khan AI, Weil AA, Aktar A, Nazim M, Larocque RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Memory B cell responses to Vibrio cholerae O1 lipopolysaccharide are associated with protection against infection in household contacts of cholera patients in Bangladesh. Clin Vaccine Immunol. 2012;19(6):842-8

137. Leung DT, Chowdhury F, Calderwood SB, Qadri F, Ryan ET. Immune responses to cholera in children. Expert Rev Anti Infect Ther. 2012; 10(4):435-44.

138. Lundgren A, Bhuiyan T, Novak D, Kaim J, Reske A, Lu YJ, Qadri F, Malley R. Characterization of Th17 responses to Streptococcus pneumoniae in humans: Comparisons

between adults and children in a developed and a developing country. Vaccine. 2012; 30(26):3897-907.

139. Leung DT, Rahman MA, Mohasin M, Patel SM, Aktar A, Khanam F, Uddin T, Riyadh MA, Saha A, Alam MM, Chowdhury F, Khan AI, Charles R, Larocque R, Harris JB, Calderwood SB, Qadri F, Ryan ET. Memory B cell and other immune responses in children receiving two doses of a killed oral cholera vaccine compared to responses following natural cholera infection in Bangladesh. Clin Vaccine Immunol. 2012; 19(5):690-8.

140. Tarique AA, Kalsy A, Arifuzzaman M, Rollins SM, Charles RC, Leung DT, Harris JB, Larocque RC, Sheikh A, Bhuiyan MS, Saksena R, Clements JD, Calderwood SB, Qadri F, Kovác P, Ryan ET. Transcutaneous immunization with a Vibrio cholerae O1 Ogawa synthetic hexasaccharide conjugate following oral whole cell cholera vaccination boosts vibriocidal responses and induces protective immunity in mice. Clin Vaccine Immunol. 2012; 19(4):594-602

141. Mohammad Arifuzzaman, Tanvir Ahmed, Mohammad Arif Rahman, Fahima Chowdhury, Rasheduzzaman Rashu, Ashraful I. Khan, Regina C. LaRocque, Jason B. Harris, Taufiqur Rahman Bhuiyan, Edward T. Ryan, Stephen B. Calderwood, Qadri F. Individuals with Le(a+b−) Blood Group Have Increased Susceptibility to Symptomatic Vibrio cholerae O1 Infection. PLoS Neglected Tropical Disease. 2011; 5(12).

142. Sheikh A, Charles RC, Sharmeen N, Rollins SM, Harris JB, Bhuiyan MS, Arifuzzaman M, Khanam F, Bukka A, Kalsy A, Porwollik S, Leung DT, Brooks WA, Larocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET. In Vivo Expression of Salmonella enterica Serotype Typhi Genes in the Blood of Patients with Typhoid Fever in Bangladesh. PLoS Negl Trop Dis. 2011; 5(12).

143. Harris JA, Roy K, Woo-Rasberry V, Hamilton DJ, Kansal R, Qadri F, Fleckenstein JM. Directed Evaluation of Enterotoxigenic Escherichia coli Autotransporter Proteins as Putative Vaccine Candidates. PLoS Negl Trop Dis. 2011; 5(12).

144. Bishop AL, Tarique AA, Patimalla B, Calderwood SB, Qadri F, Camilli A. Immunization of Mice With Vibrio cholerae Outer-Membrane Vesicles Protects Against Hyperinfectious Challenge and Blocks Transmission. J Infect Dis. 2012; 205(3):412-21.

145. Ahmed T, Bhuiyan TR, Zaman K, Qadri F, Vaccines for preventing enterotoxigenic Escherichia coli (ETEC) diarrhea (Intervention protocol), Cochrane Database Syst Rev 2011;3: CD009029

146. Saha A, Chowdhury MI, Khanam F, Bhuiyan MS, Chowdhury F, Khan AI, Khan IA, Clemens J, Ali M, Cravioto A, Qadri F. Safety and immunogenicity study of a killed bivalent (O1 and O139) whole-cell oral cholera vaccine Shanchol, in Bangladeshi adults and children as young as 1 year of age. Vaccine 2011; 29(46): 8252-8292.

147. Shin OS, Uddin T, Citorik R, Wang JP, Della Pelle P, Kradin RL, Bingle CD, Bingle L, Camilli A, Bhuiyan TR, Shirin T, Ryan ET, Calderwood SB, Finberg RW, Qadri F, Larocque RC, Harris JB. LPLUNC1 Modulates Innate Immune Responses to Vibrio cholerae. J Infect Dis. 2011; 204(9):1349-57.

148. Xu P, Alam MM, Kalsy A, Charles RC, Calderwood SB, Qadri F, Ryan ET, Kováč P, Simple, direct conjugation of bacterial O-SP-core antigens to proteins: development of cholera conjugate vaccines. Bioconjug Chem. 2011; 22(10):2179-85.

149. Son MS, Megli CJ, Kovacikova G, Qadri F, Taylor RK. Characterization of Vibrio cholerae O1 El Tor biotype variant clinical isolates from Bangladesh and Haiti, including a molecular genetic analysis of virulence genes. J Clin Microbiol. 2011; 49(11): 3739-49.

150. Shirin T, Rahman A, Danielsson A, Uddin T, Bhuyian TR, Sheikh A, Qadri SS, Qadri F, Hammarström ML. Antimicrobial peptides in the duodenum at the acute and convalescent stages in patients with diarrhea due to Vibrio cholerae O1 or enterotoxigenic Escherichia coli infection. Microbes Infect. 2011; 13(12-13):1111-20.

151. Alam NH, Raqib R, Ashraf H, Qadri F, Ahmed S, Zasloff M, Agerberth B, Salam MA, Gyr N, Meier R. L-isoleucine-supplemented oral rehydration solution in the treatment of acute diarrhoea in children: a randomized controlled trial. J Health Popul Nutr. 2011; 29(3):183-90.

152. Kuchta A, Rahman T, Sennott EL, Bhuyian TR, Uddin T, Rashu R, Chowdhurry F, Kahn AI, Arifuzzaman M, Weil AA, Podolsky M, Larocque RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Vibrio cholerae O1 Infection Induces Pro-inflammatory CD4+ T Cell Responses in Blood and Intestinal Mucosa of Infected Humans. Clin Vaccine Immunol. 2011; 18(8):1371-7.

153. Leung DT, Rahman MA, Mohasin M, Riyadh MA, Patel SM, Alam MM, Chowdhury F, Khan AI, Kalivoda EJ, Aktar A, Bhuiyan MS, Larocque RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. A comparison of memory B cell, antibody secreting cell, and plasma antibody responses in young children, older children, and adults with infection caused by Vibrio cholerae O1 El Tor Ogawa in Bangladesh. Clin Vaccine Immunol. 2011; 18(8):1317-25.

154. Sheikh A, Khanam F, Sayeed MA, Rahman T, Pacek M, Hu Y, Rollins A, Bhuiyan MS, Rollins S, Kalsy A, Arifuzzaman M, Leung DT, Sarracino DA, Krastins B, Charles RC, Larocque RC, Cravioto A, Calderwood SB, Brooks WA, Harris JB, Labaer J, Qadri F, Ryan ET. Interferon-γ and Proliferation Responses to Salmonella enterica Serotype Typhi Proteins in Patients with S. Typhi Bacteremia in Dhaka, Bangladesh. PLoS Negl Trop Dis. 2011; 5(6).

155. Sinclair D, Abba K, Zaman K, Qadri F, Graves PM. Oral vaccines for preventing cholera. Cochrane Database Syst Rev. 2011; 16 ;( 3):CD008603.

156. Chowdhury F, Rahman MA, Begum YA, Khan AI, Faruque AS, Saha NC, Baby NI, Malek MA, Kumar AR, Svennerholm AM, Pietroni M, Cravioto A, Qadri F. Impact of rapid urbanization on the rates of infection by Vibrio cholerae O1 and enterotoxigenic Escherichia coli in Dhaka, Bangladesh. PLoS Negl Trop Dis. 2011; 5(4).

157. Islam MS, Mahmud ZH, Ansaruzzaman M, Faruque SM, Talukder KA, Qadri F, Alam M, Islam S, Bardhan PK, Mazumder RN, Khan AI, Ahmed S, Iqbal A, Chitsatso O, Mudzori J, Patel S, Midzi SM, Charimari L, Endtz HP, Cravioto A. Phenotypic, genotypic, and antibiotic sensitivity patterns of strains isolated from the cholera epidemic in Zimbabwe. J Clin Microbiol. 2011; 49(6):2325-7.

158. Alam MM, Riyadh MA, Fatema K, Rahman MA, Akhtar N, Ahmed T, Chowdhury MI, Chowdhury F, Calderwood SB, Harris JB, Ryan ET, Qadri F., Antigen-specific memory B-cell responses in Bangladeshi adults after one- or two-dose oral killed cholera vaccination and comparison with responses in patients with naturally acquired cholera. Clin Vaccine Immunol. 2011; 18(5):844-50.

159. Seed KD, Bodi KL, Kropinski AM, Ackermann HW, Calderwood SB, Qadri F, Camilli A. Evidence of a Dominant Lineage of Vibrio cholerae-Specific Lytic Bacteriophages Shed by Cholera Patients over a 10-Year Period in Dhaka, Bangladesh. mBio. 2011; 2(1).

160. Uddin T, Harris JB, Bhuiyan TR, Shirin T, Uddin MI, Khan AI, Chowdhury F, Larocque RC, Alam MN, Ryan ET, Calderwood SB, Qadri F. Mucosal immunologic responses in cholera patients in Bangladesh. Clin Vaccine Immunol. 2011; 18(3):506-12.

161. Matsuda F, Chowdhury MI, Saha A, Asahara T, Nomoto K, Tarique AA, Ahmed T, Nishibuchi M, Cravioto A, Qadri F. Evaluation of a probiotics, Bifidobacterium breve BBG-01, for enhancement of immunogenicity of an oral inactivated cholera vaccine and safety: A randomized, double-blind, placebo-controlled trial in Bangladeshi children under 5 years of age. Vaccine. 2011; 29(10):1855-8.

162. Sheikh A, Charles RC, Rollins SM, Harris JB, Bhuiyan MS, Khanam F, Bukka A, Kalsy A, Porwollik S, Brooks WA, LaRocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET. Analysis of Salmonella enterica serotype paratyphi A gene expression in the blood of bacteremic patients in Bangladesh. PLoS Negl Trop Dis. 2010; 4(12).

163. Bhuiyan TR, Saha A, Lundgren A, Qadri F, Svennerholm AM. Immune responses to Helicobacter pylori infection in Bangladeshi children during their first two years of life and the association between maternal antibodies and onset of infection. J Infect Dis. 2010; 202(11):1676-84.

164. Roy K, Bartels S, Qadri F, Fleckenstein JM. Enterotoxigenic Escherichia coli elicits immune responses to multiple surface proteins. Infect Immun. 2010; 78(7):3027-35.

165. Kendall EA, Chowdhury F, Begum Y, Khan AI, Li S, Thierer JH, Bailey J, Kriesel K, Tacket CO, Larocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB, Stine OC. Relatedness of Vibrio cholerae O1/O139 from patients and their household contacts, determined by multilocus variable number tandem repeat analysis (MLVA). J Bacteriol. 2010; 192(17):4367-76.

166. Charles RC, Sheikh A, Krastins B, Harris JB, Bhuiyan MS, Larocque RC, Logvinenko T, Sarracino DA, Kudva IT, Eisenstein J, Podolsky MJ, Kalsy A, Brooks WA, Ludwig A, John M, Calderwood SB, Qadri F, Ryan ET. Characterization of anti-Salmonella enterica serotype Typhi antibody responses in bacteremic Bangladeshi patients using Immuno-affinity Proteomic-based Technology (IPT). Clin Vaccine Immunol. 2010; 17(8):1188-95.

167. Larson CP, Nasrin D, Saha A, Chowdhury MI, Qadri F. The added benefit of zinc supplementation after zinc treatment of acute childhood diarrhoea: a randomized, double-blind field trial. Trop Med Int Health. 2010; 15(6):754-61.

168. Sheikh A, Shamsuzzaman S, Ahmad SM, Nasrin D, Nahar S, Alam MM, Al Tarique A, Begum YA, Qadri SS, Chowdhury MI, Saha A, Larson CP, Qadri F. Zinc influences innate immune responses in children with enterotoxigenic Escherichia coli-induced diarrhea. J Nutr. 2010; 140(5):1049-56.

169. Chowdhury F, Begum YA, Alam MM, Khan AI, Ahmed T, Bhuiyan MS, Harris JB, Larocque RC, Faruque AS, Endtz H, Ryan ET, Cravioto A, Svennerholm AM, Calderwood SB, Qadri F. Concomitant Enterotoxigenic E. coli Infection Induces Increased Immune Responses to Vibrio cholerae O1 Antigens in Patients with Cholera in Bangladesh. Infect Immun. 2010; 78(5):2117-24.

170. Rahman KM, Duggal P, Harris JB, Saha SK, Streatfield PK, Ryan ET, Calderwood SB, Qadri F, Yunus M, LaRocque RC. Familial aggregation of Vibrio cholerae-associated infection in Matlab, Bangladesh. J Health Popul Nutr. 2009; 27(6):733-8.

171. Begum YA, Chakraborty S, Chowdhury A, Ghosh AN, Nair GB, Sack RB, Svennerholm AM, Qadri F. Isolation of a bacteriophage specific for CS7-expressing strains of enterotoxigenic Escherichia coli. J Med Microbiol. 2010; 59(Pt 3):266-72.

172. Kim HB, Wang M, Ahmed S, Park CH, LaRocque RC, Faruque AS, Salam MA, Khan WA, Qadri F, Calderwood SB, Jacoby GA, Hooper DC. Transferable quinolone resistance in Vibrio cholerae. Antimicrob Agents Chemother. 2010; 54(2):799-803.

173. Chowdhury MI, Sheikh A, Qadri F. Development of Peru-15 (CholeraGarde), a live-attenuated oral cholera vaccine: 1991-2009. Expert Rev Vaccines. 2009; 8(12):1643-52. Review.

174. Khan AI, Chowdhury F, Harris JB, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F. Comparison of clinical features and immunological parameters of patients with dehydrating diarrhoea infected with Inaba or Ogawa serotypes of Vibrio cholerae O1. Scand J Infect Dis. 2010; 42(1):48-56.

175. Kendall EA, Tarique AA, Hossain A, Alam MM, Arifuzzaman M, Akhtar N, Chowdhury F, Khan AI, Larocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Development of immunoglobulin M memory to both a T-cell-independent and a T-cell-dependent antigen following infection with Vibrio cholerae O1 in Bangladesh. Infect Immun. 2010; 78(1):253-9.

176. Weil AA, Khan AI, Chowdhury F, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F, Harris JB. Clinical outcomes in household contacts of patients with cholera in Bangladesh. Clin Infect Dis. 2009; 49(10):1473-9.

177. Ahmed T, Arifuzzaman M, Lebens M, Qadri F, Lundgren A. CD4+ T-cell responses to an oral inactivated cholera vaccine in young children in a cholera endemic country and the enhancing effect of zinc supplementation. Vaccine. 2009; 28(2):422-9.

178. Charles RC, Harris JB, Chase MR, Lebrun LM, Sheikh A, LaRocque RC, Logvinenko T, Rollins SM, Tarique A, Hohmann EL, Rosenberg I, Krastins B, Sarracino DA, Qadri F,

Calderwood SB, Ryan ET. Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. PLoS One. 2009; 4(9).

179. Sheikh A, Bhuiyan MS, Khanam F, Chowdhury F, Saha A, Ahmed D, Jamil KM, LaRocque RC, Harris JB, Ahmad MM, Charles R, Brooks WA, Calderwood SB, Cravioto A, Ryan ET, Qadri F. Salmonella enterica serovar Typhi-specific immunoglobulin A antibody responses in plasma and antibody in lymphocyte supernatant specimens in Bangladeshi patients with suspected typhoid fever. Clin Vaccine Immunol. 2009; 16(11):1587-94.

180. Weil AA, Arifuzzaman M, Bhuiyan TR, LaRocque RC, Harris AM, Kendall EA, Hossain A, Tarique AA, Sheikh A, Chowdhury F, Khan AI, Murshed F, Parker KC, Banerjee KK, Ryan ET, Harris JB, Qadri F, Calderwood SB. Memory T-cell responses to Vibrio cholerae O1 infection. Infect Immun. 2009; 77(11):5090-6.

181. Siddique AK, Nair GB, Alam M, Sack DA, Huq A, Nizam A, Longini IM, Qadri F, Faruque SM, Colwell RR, Ahmed S, Iqbal A, Bhuiyan NA, Sack RB. El Tor cholera with severe disease: a new threat to Asia and beyond. Epidemiol Infect. 2010; 138(3):347-52.

182. Janzon A, Bhuiyan T, Lundgren A, Qadri F, Svennerholm AM, Sjöling A. Presence of high numbers of transcriptionally active Helicobacter pylori in vomitus from Bangladeshi patients suffering from acute gastroenteritis. Helicobacter. 2009; 14(4):237-47.

183. Sarker P, Bhuiyan TR, Qadri F, Alam NH, Wretlind B, Bishop AE, Mathan M, Agerberth B, Andersson J, Raqib R. Differential expression of enteric neuroimmune-network in invasive and acute watery diarrhoea. Neurogastroenterol Motil. 2010; 22(1):70-8.

184. Rollenhagen JE, Kalsy A, Saksena R, Sheikh A, Alam MM, Qadri F, Calderwood SB, Kovác P, Ryan ET. Transcutaneous immunization with a synthetic hexasaccharide-protein conjugate induces anti-Vibrio cholerae lipopolysaccharide responses in mice. Vaccine. 2009; 27(36):4917-22.

185. Harris AM, Bhuiyan MS, Chowdhury F, Khan AI, Hossain A, Kendall EA, Rahman A, LaRocque RC, Wrammert J, Ryan ET, Qadri F, Calderwood SB, Harris JB. Antigen-specific memory B-cell responses to Vibrio cholerae O1 infection in Bangladesh. Infect Immun. 2009; 77(9):3850-6.

186. Blackburn D, Husband A, Saldaña Z, Nada RA, Klena J, Qadri F, Girón JA. Distribution of the Escherichia coli common pilus among diverse strains of human enterotoxigenic E. coli. J Clin Microbiol. 2009; 47(6):1781-4.

187. Harris JB, Podolsky MJ, Bhuiyan TR, Chowdhury F, Khan AI, Larocque RC, Logvinenko T, Kendall J, Faruque AS, Nagler CR, Ryan ET, Qadri F, Calderwood SB. Immunologic Responses to Vibrio cholerae in Patients Co-Infected with Intestinal Parasites in Bangladesh. PLoS Negl Trop Dis. 2009; 3(3).

188. Nelson EJ, Tanudra A, Chowdhury A, Kane AV, Qadri F, Calderwood SB, Coburn J, Camilli A.High prevalence of spirochetosis in cholera patients, Bangladesh. Emerg Infect Dis. 2009; 15(4):571-3.

189. Janzon A, Sjöling A, Lothigius A, Ahmed D, Qadri F, Svennerholm AM. Failure to detect Helicobacter pylori DNA in drinking and environmental water in Dhaka, Bangladesh, using highly sensitive real-time PCR assays. Appl Environ Microbiol. 2009; 75(10):3039-44.

190. Ahmed T, Lundgren A, Arifuzzaman M, Qadri F, Teneberg S, Svennerholm AM. Children with the Le(a+b-) blood group have increased susceptibility to diarrhea caused by enterotoxigenic Escherichia coli expressing colonization factor I group fimbriae. Infect Immun. 2009; 77(5):2059-64.

191. Rodas C, Iniguez V, Qadri F, Wiklund G, Svennerholm AM, Sjöling A. Development of multiplex PCR assays for detection of enterotoxigenic Escherichia coli colonization factors and toxins. J Clin Microbiol. 2009; 47(4):1218-20.

192. Bhuiyan TR, Lundin SB, Khan AI, Lundgren A, Harris JB, Calderwood SB, Qadri F. Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation. Infect Immun. 2009; 77(5):1888-93.

193. Larocque RC, Sabeti P, Duggal P, Chowdhury F, Khan AI, Lebrun LM, Harris JB, Ryan ET, Qadri F, Calderwood SB A variant in long palate, lung and nasal epithelium clone 1 is associated with cholera in Bangladeshi population. Genes Immun. 2009; 10(3):267-72.

194. Ahmed T, Svennerholm AM, Al Tarique A, Sultana GN, Qadri F. Enhanced immunogenicity of an oral inactivated cholera vaccine in infants in Bangladesh obtained by zinc supplementation and by temporary withholding breast-feeding. Vaccine. 2009; 27(9):1433-9.

195. Shamsuzzaman S, Ahmed T, Mannoor K, Begum YA, Bardhan PK, Sack RB, Sack DA, Svennerholm AM, Holmgren J, Qadri F. Robust gut associated vaccine-specific antibody-secreting cell responses are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral killed bivalent V. cholerae O1/O139 whole cell cholera vaccine: comparison with other mucosal and systemic responses. Vaccine. 2009; 27(9):1386-92.

196. Bhuiyan TR, Qadri F, Saha A, Svennerholm AM. Infection by Helicobacter pylori in Bangladeshi children from birth to two years: relation to blood group, nutritional status, and seasonality. Pediatr Infect Dis J. 2009; 28(2):79-85.

197. Harris AM, Chowdhury F, Begum YA, Khan AI, Faruque AS, Svennerholm AM, Harris JB, Ryan ET, Cravioto A, Calderwood SB, Qadri F. Shifting prevalence of major diarrheal pathogens in patients seeking hospital care during floods in 1998, 2004, and 2007 in Dhaka, Bangladesh. Am J Trop Med Hyg. 2008; 79(5):708-14.

198. Bhuiyan TR, Qadri F, Bardhan PK, Ahmad MM, Kindlund B, Svennerholm AM, Lundgren A. Comparison of mucosal B- and T-cell responses in Helicobacter pylori-infected subjects in a developing and a developed country. FEMS Immunol Med Microbiol.2008; 54(1): 70-9

199. Sears CL, Islam S, Saha A, Arjumand M, Alam NH, Faruque AS, Salam MA, Shin J, Hecht D, Weintraub A, Sack RB, Qadri F “Association of enterotoxigenic Bacteroides fragilis infection with inflammatory diarrhea”. Clin Infect Dis. 2008; 47(6):797-803

200. Larson CP, Roy SK, Khan AI, Rahman AS, Qadri F. Zinc treatment to under five

children: applications to improve child survival and reduce burden of disease. J Health Popul Nut. 2008, 26(3):356-65

201. Harris JB, Larocque RC, Chowdhury F, Khan AI, Logvinenko T, Faruque AS, Ryan ET, Qadri F, Calderwood SB. Susceptibility to Vibrio cholerae Infection in a Cohort of Household Contacts of Patients with Cholera in Bangladesh. PLoS Negl Trop Dis. 2008 9;2(4): e221

202. Sack DA, Qadri F, Svennerholm AM, Determinants of Responses to Oral Vaccines in Developing Countries- Ann. Nestle 2008; 66:71-79.

203. Morita M, Ohnishi M, Arakawa E, Bhuiyan NA, Nusrin S, Alam M, Siddique AK, Qadri F, Izumiya H, Nair GB, Watanabe H. Development and validation of a mismatch amplification mutation PCR assay to monitor the dissemination of an emerging variant of Vibrio cholerae O1 biotype El Tor. 2008; 52(6):314-7.

204. Nelson EJ, Chowdhury A, Flynn J, Schild S, Bourassa L, Shao Y, LaRocque RC, Calderwood SB, Qadri F, Camilli A. Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the aquatic environment. 2008; 4(10).

205. LaRocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB,Qadri F,A Proteomic Analysis of Vibrio cholerae in human Stool – Infect Immun. 2008, 76(9):4145-51

206. T Ahmed and Qadri F-Enteroxigenic Escherichia coli’s Endemicity in Developing Countries and Its Emergence during Diarrheal Epidemics and Natural Disaster. Emerging Infections in Asia.-2008,163-177.

207. Channa R Jayasekera, Jason B Harris, Md. Saruar Bhuiyan, Fahima Chowdhury, Ashraful I Khan, Abu S.G Faruque, John Glidewell, Regina C LaRocque, Edward T Ryan, Rafi Ahmed, Qadri F, Stephen B Calderwood. Cholera toxin-specific memory B cell responses are induced in patients with dehydrating diarrhea caused by V.cholerae O1. J Infect Dis. 2008, 198(7): 1056-61.

208. Fahima Chowdhury, M.B.B.S.; Qadri F ; Ashraful I Khan, M.B.B.S., M.Sc.;Jason B Harris, M.D., M.P.H.; Regina C LaRocque, M.D., M.P.H.; Mohiul I Chowdhury, M.B.B.S., M.P.H.;Edward T Ryan; ASG Faruque, M.B.B.S., M.P.H. ; Stephen B Calderwood , M.D. A comparison of clinical and immunologic features in children and older patients hospitalized with severe cholera in Bangladesh –Pediatr Infect Dis J. 2008, 27(11): 986-92.

209. Ahmed F, André-Leroux G, Haouz A, Boutonnier A, Delepierre M, Qadri F, Nato F, Fournier JM, Alzari PM. Crystal structure of a monoclonal antibody directed against an antigenic determinant common to Ogawa and Inaba serotypes of Vibrio cholerae O1. 2008 70(1): 284-8

210. Svennerholm A-M, Qadri F. Mucosal immune responses against enterotoxigenic Escherichia coli (ETEC) in humans. In Immunity against Mucosal pathogens (M Vajdy, ed), Springer Verlag – 2008

211. Lothigius A, Janzon A, Begum Y, Sjöling A, Qadri F, Svennerholm AM, Bölin I. Enterotoxigenic Escherichia coli is detectable in water samples from an endemic area by real-time PCR. J Appl Microbiol. 2008;104(4):1128-36

212. Qadri F, Saha A, Ahmed T, Al Tarique A, Begum YA, Svennerholm A M. Disease burden due to enterotoxigenic Escherichia coli in the first 2 years of life in an urban community in Bangladesh.Infect Immun. 2007; 75: 3961-8.

213. Qadri F, Ahmed T, Ahmed F, Bhuiyan MS, Mostofa MG, Cassels FJ, Helander A, Svennerholm AM. Mucosal and systemic immune responses in patients with diarrhea due to CS6-expressing enterotoxigenic Escherichia coli. Infect Immun. 2007; 75: 2269-74.

214. Qadri F, Chowdhury MI, Faruque SM, Salam MA, Ahmed T, Begum YA, Saha A, Al Tarique A, Seidlein LV, Park E, Killeen KP, Mekalanos JJ, Clemens JD, Sack DA; the PXV Study Group. Peru-15, a live attenuated oral cholera vaccine, is safe and immunogenic in Bangladeshi toddlers and infants. Vaccine. 2007; 25:231-8.

215. Begum YA, Talukder KA, Nair GB, Khan SI, Svennerholm AM, Sack RB, Qadri F. Comparison of enterotoxigenic Escherichia coli isolated from surface water and diarrhoeal stool samples in Bangladesh. Can J Microbiol. 2007; 53:19-26.

216. S child S, Tamayo R, Nelson EJ, Qadri F, Calderwood SB, Camilli A. Genes induced late in infection increase fitness of Vibrio cholerae after release into the environment. 2007; 2(4):264-77.

217. Flach CF, Qadri F, Bhuiyan TR, Alam NH, Jennische E, Holmgren J, Lonnroth I. Differential expression of intestinal membrane transporters in cholera patients. FEBS Lett. 2007; 581:3183-8.

218. Ahmed T and Qadri F. Enterotoxigenic Escherichia coli’s endemicity in developing countries and its emergence during diarrheal epidemics and natural disasters. Growing Infections in Asia. 2007. Springer publications

219. Ghose C, Kalsy A, Sheikh A, Rollenhagen J, John M, Young J, Rollins SM, Qadri F, Calderwood SB, Kelly CP, Ryan ET. Transcutaneous immunization with Clostridium difficile toxoid A induces systemic and mucosal immune responses and toxin A-neutralizing antibodies in mice. Infect Immun. 2007; 75:2826-32.

220. Flach CF, Qadri F, Bhuiyan TR, Alam NH, Jennische E, Lonnroth I, Holmgren J. Broad up-regulation of innate defense factors during acute cholera.Infect Immun. 2007; 75:2343-50.

221. Nelson EJ, Chowdhury A, Harris JB, Begum YA, Chowdhury F, Khan AI, Larocque RC, Bishop AL, Ryan ET, Camilli A, Qadri F, Calderwood SB. Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea “2007; 104(48):19091-6.

222. Ansaruzzaman M, Bhuiyan NA, Begum YA, Kuhn I, Nair GB, Sack DA, Svennerholm AM, Qadri F. Characterization of enterotoxigenic Escherichia coli from diarrhoeal patients in Bangladesh using phenotyping and genetic profiling. J Med Microbiol. 2007; 56:217-22.

223. Qadri F, Ahmed T, Ahmed F, Begum YA, Sack DA, Svennerholm AM; PTE Study Group. Reduced doses of oral killed enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine is safe and immunogenic in Bangladeshi infants 6-17 months of age: dosing studies in different age groups. Vaccine. 2006; 24:1726-33.

224. Qadri F, Ahmed F, Ahmed T, Svennerholm AM. Homologous and cross-reactive immune responses to enterotoxigenic Escherichia coli colonization factors in Bangladeshi children. Infect Immun. 2006; 74:4512-8.

225. LaRocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Postgenomic approaches to cholera vaccine development. Expert Rev Vaccines. 2006; 5:337-46.

226. Sjoling A, Qadri F, Nicklasson M, Begum YA, Wiklund G, Svennerholm AM. In vivo expression of the heat stable (estA) and heat labile (eltB) toxin genes of enterotoxigenic Escherichia coli (ETEC). Microbes Infect. 2006; 8: 2797-802.

227. Ryan ET, Calderwood SB, Qadri F. Live attenuated oral cholera vaccines. Expert Rev Vaccines. 2006; 5: 483-94.

228. Rollenhagen JE, Kalsy A, Cerda F, John M, Harris JB, Larocque RC, Qadri F, Calderwood SB, Taylor RK, Ryan ET. Transcutaneous immunization with toxin-coregulated pilin A induces protective immunity against Vibrio cholerae O1 El Tor challenge in mice.Infect Immun. 2006; 74:5834-9.

229. Nair GB, Qadri F, Holmgren J, Svennerholm AM, Safa A, Bhuiyan NA, Ahmad QS, Faruque SM, Faruque AS, Takeda Y, Sack DA. Cholera due to altered El Tor strains of Vibrio cholerae O1in Bangladesh.J Clin Microbiol. 2006 44:4211-3.

230. Bolin I, Wiklund G, Qadri F, Torres O, Bourgeois AL, Savarino S, Svennerholm AM. Enterotoxigenic Escherichia coli with STh and STp genotypes is associated with diarrhea both in children in areas of endemicity and in travelers. J Clin Microbiol. 2006; 44:3872-7.

231. Harris JB, Baresch-Bernal A, Rollins SM, Alam A, LaRocque RC, Bikowski M, Peppercorn AF, Handfield M, Hillman JD, Qadri F, Calderwood SB, Hohmann E, Breiman RF, Brooks WA, Ryan ET. Identification of in vivo-induced bacterial protein antigens during human infection with Salmonella enterica serovar Typhi. Infect Immun. 2006; 74:5161-8.

232.233. Schwartz BS, Harris JB, Khan AI, Larocque RC, Sack DA, Malek MA, Faruque AS,

Qadri F, Calderwood SB, Luby SP, Ryan ET. Diarrheal epidemics in Dhaka, Bangladesh, during three consecutive floods: 1988, 1998, and 2004. Am J Trop Med Hyg. 2006; 74:1067-73.

234. Qadri F, Chowdhury NR, Takeda Y, Nair GB. 2005. Vibrio parahaemolyticus, seafood safety and associations with higher organisms. In: Oceans and Health: Pathogens in the Marine Environment. Edited by Belkin and Colwell, Springer, New York, USA.

235. Qadri F, Chowdhury MI, Faruque SM, Salam MA, Ahmed T, Begum YA, Saha A, Alam MS, Zaman K, Seidlein LV, Park E, Killeen KP, Mekalanos JJ, Clemens JD, Sack DA; Peru-15 Study Group. Randomized, controlled study of the safety and immunogenicity of Peru-15, a live attenuated oral vaccine candidate for cholera, in adult volunteers in Bangladesh. J Infect Dis. 2005; 192:573-9.

236. Qadri F, Khan AI, Faruque AS, Begum YA, Chowdhury F, Nair GB, Salam MA, Sack DA, Svennerholm AM. Enterotoxigenic Escherichia coli and Vibrio cholerae diarrhea, Bangladesh, 2004. Emerg Infect Dis. 2005; 11:1104-7.

237. Qadri F, Svennerholm AM, Faruque AS, Sack RB. Enterotoxigenic Escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and prevention. Clin Microbiol Rev. 2005; 18:465-83.

238. Qadri F, Svennerholm AM, Shamsuzzaman S, Bhuiyan TR, Harris JB, Ghosh AN, Nair GB, Weintraub A, Faruque SM, Ryan ET, Sack DA, Calderwood SB. Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in Bangladesh. Infect Immun. 2005; 73: 6577-83.

239. Harris JB, Khan AI, LaRocque RC, Dorer DJ, Chowdhury F, Faruque AS, Sack DA, Ryan ET, Qadri F, Calderwood SB. Blood group, immunity, and risk of infection with Vibrio cholerae in an area of endemicity. Infect Immun. 2005; 73:7422-7.

240. Alam A, Larocque RC, Harris JB, Vanderspurt C, Ryan ET, Qadri F, Calderwood SB. Hyperinfectivity of human-passaged Vibrio cholerae can be modeled by growth in the infant mouse. Infect Immun. 2005; 73:6674-9.

241. Falklind-Jerkerus S, Felici F, Cavalieri C, Lo Passo C, Garufi G, Pernice I, Islam MM, Qadri F, Weintraub A. Peptide’s mimicking Vibrio cholerae O139 capsular polysaccharide elicit protective antibody response. Microbes Infect. 2005; 7:1453-60.

242. Larocque RC, Harris JB, Dziejman M, Li X, Khan AI, Faruque AS, Faruque SM, Nair GB, Ryan ET, Qadri F, Mekalanos JJ, Calderwood SB. Transcriptional profiling of Vibrio cholerae recovered directly from patient specimens during early and late stages of human infection. Infect Immun. 2005; 7:4488-93.

243. Begum YA, Talukder KA, Nair GB, Qadri F, Sack RB, Svennerholm AM. Enterotoxigenic Escherichia coli isolated from surface water in urban and rural areas of Bangladesh. J Clin Microbiol. 2005; 43:3582-3.

244. Faruque SM, Bin Naser I, Fujihara K, Diraphat P, Chowdhury N, Kamruzzaman M, Qadri F, Yamasaki S, Ghosh AN, Mekalanos JJ. Genomic sequence and receptor for the Vibrio cholerae phage KSF-1phi: evolutionary divergence among filamentous vibriophages mediating lateral gene transfer. J Bacteriol. 2005; 187:4095-103.

245. Asaduzzaman M, Ryan ET, John M, Hang L, Khan AI, Faruque AS, Taylor RK, Calderwood SB, Qadri F. The major subunit of the toxin-coregulated pilus TcpA induces mucosal and systemic immunoglobulin A immune responses in patients with cholera caused by Vibrio cholerae O1 and O139. Infect Immun. 2004; 72:4448-54.

246. Saha D, LaRocque RC, Khan AI, Harris JB, Begum YA, Akramuzzaman SM, Faruque AS, Ryan ET, Qadri F, Calderwood SB. Incomplete correlation of serum vibriocidal antibody titer with protection from Vibrio cholerae infection in urban Bangladesh. J Infect Dis. 2004; 189:2318-22. 247. Attridge SR, Wallerstrom G, Qadri F, Svennerholm AM. Detection of antibodies

to toxin-coregulated pili in sera from cholera patients. Infect Immun. 2004; 72:1824-7.

248. Shibani-Chennoufi S, Sidoti J, Bruttin A, Dillmann ML, Kutter E, Qadri F, Sarker SA, Brussow H. Isolation of Escherichia coli bacteriophages from the stool of pediatric diarrhea patients in Bangladesh. J Bacteriol. 2004; 186:8287-94.

249. Qadri F, Bhuiyan TR, Dutta KK, Raqib R, Alam MS, Alam NH, Svennerholm AM, Mathan MM. Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induce increases in innate cells and inflammatory mediators at the mucosal surface of the gut. Gut. 2004; 5:62-9.

250. Qadri F, Ahmed T, Wahed MA, Ahmed F, Bhuiyan NA, Rahman AS, Clemens JD, Black RE, Albert MJ. Suppressive effect of zinc on antibody response to cholera toxin in children given the killed, B subunit-whole cell, oral cholera vaccine. Vaccine. 2004; 22:416-21.

251. Bhuiyan NA, Qadri F, Faruque AS, Malek MA, Salam MA, Nato F, Fournier JM, Chanteau S, Sack DA, Balakrish Nair G. Use of dipsticks for rapid diagnosis of cholera caused by Vibrio cholerae O1 and O139 from rectal swabs. J Clin Microbiol. 2003; 41:3939-41.

252. Qadri F, Ryan ET, Faruque AS, Ahmed F, Khan AI, Islam MM, Akramuzzaman SM, Sack DA, Calderwood SB. Antigen-specific immunoglobulin A antibodies secreted from circulating B cells are an effective marker for recent local immune responses in patients with cholera: comparison to antibody-secreting cell responses and other immunological markers. Infect Immun. 2003; 71:4808-14.

253. Qadri F, Ahmed T, Ahmed F, Bradley Sack R, Sack DA, Svennerholm AM. Safety and immunogenicity of an oral, inactivated enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine in Bangladeshi children 18-36 months of age. Vaccine. 2003; 21:2394-403.

254. Raqib R, Moly PK, Sarker P, Qadri F, Alam NH, Mathan M, Andersson J. Persistence of mucosal mast cells and eosinophils in Shigella-infected children. Infect Immun. 2003; 71(5):2684-92.

255. Albert MJ, Qadri F, Wahed MA, Ahmed T, Rahman AS, Ahmed F, Bhuiyan NA, Zaman K, Baqui AH, Clemens JD, Black RE. Supplementation with zinc, but not vitamin A, improves seroconversion to vibriocidal antibody in children given an oral cholera vaccine. J Infect Dis. 2003; 187(6): 909-13.

256. Qadri F, Alam MS, Nishibuchi M, Rahman T, Alam NH, Chisti J, Kondo S, Sugiyama J, Bhuiyan NA, Mathan MM, Sack DA, Nair GB. Adaptive and inflammatory immune responses in patients infected with strains of Vibrio parahaemolyticus. J Infect Dis. 2003; 187(7): 1085-96.

257. Sack RB, Siddique AK, Longini IM Jr, Nizam A, Yunus M, Islam MS, Morris JG Jr, Ali A, Huq A, Nair GB, Qadri F, Faruque SM, Sack DA, Colwell RR. A 4-year study of the epidemiology of Vibrio cholerae in four rural areas of Bangladesh. J Infect Dis. 2003; 187(1): 96-101.

258. Merrell DS, Butler SM, Qadri F, Dolganov NA, Alam A, Cohen MB, Calderwood SB, Schoolnik GK, Camilli A. Host-induced epidemic spread of the cholera bacterium. Nature. 2002; 417(6889):642-5.

259. Pichel MG, Binsztein N, Qadri F, Giron JA. Type IV longus pilus of enterotoxigenic Escherichia coli: occurrence and association with toxin types and colonization factors among strains isolated in Argentina. J Clin Microbiol. 2002; 40(2): 694-7.

260. Raqib R, Qadri F, SarkEr P, Mia SM, Sansonnetti PJ, Albert MJ, Andersson J. Delayed and reduced adaptive humoral immune responses in children with shigellosis compared with in adults. Scand J Immunol. 2002; 55(4): 414-23.

261. Attridge SR, Johansson C, Trach DD, Qadri F, Svennerholm AM. Sensitive microplate assay for detection of bactericidal antibodies to Vibrio cholerae O139. Clin Diagn Lab Immunol. 2002; 9(2):383-7.

262. Qadri F, Raqib R, Ahmed F, Rahman T, Wenneras C, Das SK, Alam NH, Mathan MM, Svennerholm AM. Increased levels of inflammatory mediators in children and adults infected with Vibrio cholerae O1 and O139. Clin Diagn Lab Immunol. 2002; 9(2): 221-9.

263. Qadri F, Asaduzzaman M, Wenneras C, Mohi G, Albert MJ, Abdus Salam M, Sack RB, Jertborn M, McGhee JR, Sack DA, Holmgren J. Enterotoxin-specific immunoglobulin E responses in humans after infection or vaccination with diarrhea-causing enteropathogens. Infect Immun. 2000; 68(10): 6077-81.

264. Qadri F, Giron JA, Helander A, Begum YA, Asaduzzaman M, Xicohtencatl-Cortes J, Negrete E, Albert MJ. Human antibody response to longus type IV pilus and study of its prevalence among enterotoxigenic Escherichia coli in Bangladesh by using monoclonal antibodies. J Infect Dis. 2000; 181(6): 2071-4.

265. Raqib R, Mia SM, Qadri F, Alam TI, Alam NH, Chowdhury AK, Mathan MM, Andersson J. Innate immune responses in children and adults with Shigellosis. Infect Immun. 2000; 68(6): 3620-9.

266. Gutierrez-Cazarez Z, Qadri F, Albert MJ, Giron JA. Identification of enterotoxigenic Escherichia coli harboring longus type IV pilus gene by DNA amplification. J Clin Microbiol. 2000; 38(5):1767-71.

267. Attridge SR, Qadri F, Albert MJ, Manning PA. Susceptibility of Vibrio cholerae O139 to antibody-dependent, complement-mediated bacteriolysis. Clin Diagn Lab Immunol. 2000; 7(3):444-50.

268. Qadri F, Wenneras C, Ahmed F, Asaduzzaman M, Saha D, Albert MJ, Sack RB, Svennerholm A. Safety and immunogenicity of an oral, inactivated enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine in Bangladeshi adults and children. Vaccine. 2000; 18(24):2704-12.

269. Qadri F, Das SK, Faruque AS, Fuchs GJ, Albert MJ, Sack RB, Svennerholm AM. Prevalence of toxin types and colonization factors in enterotoxigenic Escherichia coli isolated during a 2-year period from diarrheal patients in Bangladesh. J Clin Microbiol. 2000; 38(1):27-31.

270. Wenneras C, Qadri F, Bardhan PK, Sack RB, Svennerholm AM. Intestinal immune responses in patients infected with enterotoxigenic Escherichia coli and in vaccinees. Infect Immun. 1999; 67(12):6234-41.

271. Qadri F, Ahmed F, Karim MM, Wenneras C, Begum YA, Abdus Salam M, Albert MJ, McGhee JR. Lipopolysaccharide- and cholera toxin-specific subclass distribution of B-cell responses in cholera. Clin Diagn Lab Immunol. 1999; 6(6):812-8.

272. Albert MJ, Qadri F, Bhuiyan NA, Ahmad SM, Ansaruzzaman M, Weintraub A. Phagocytosis of Vibrio cholerae O139 Bengal by human polymorphonuclear leukocytes. Clin Diagn Lab Immunol. 1999; 6(2):276-8.

273. Azim T, Rashid A, Qadri F, Sarker MS, Hamadani J, Salam MA, Wahed MA, Albert MJ. Antibodies to Shiga toxin in the serum of children with Shigella-associated haemolytic uraemic syndrome. J Med Microbiol. 1999; 48(1):11-6.

274. Helander A, Wenneras C, Qadri F, Svennerholm AM. Antibody responses in humans against coli surface antigen 6 of enterotoxigenic Escherichia coli. Infect Immun. 1998; 66(9):4507-10.

275. Qadri F, Makela PH, Holmgren J, Albert MJ, Mannoor K, Kantele A, Saha D, Salam MA, Kantele JM. Enteric infections in an endemic area induce a circulating antibody-secreting cell response with homing potentials to both mucosal and systemic tissues. J Infect Dis. 1998; 177(6):1594-9.

276. Rudin A, Wiklund G, Wenneras C, Qadri F. Infection with colonization factor antigen I-expressing enterotoxigenic Escherichia coli boosts antibody responses against heterologous colonization factors in primed subjects. Epidemiol Infect.1997;119(3):391-3.

277. Qadri F, Wenneras C, Albert MJ, Hossain J, Mannoor K, Begum YA, Mohi G, Salam MA, Sack RB, Svennerholm AM. Comparison of immune responses in patients infected with Vibrio cholerae O139 and O1. Infect Immun. 1997; 65(9):3571-6.

278. Qadri F, Jonson G, Begum YA, Wenneras C, Albert MJ, Salam MA, Svennerholm AM. Immune response to the mannose-sensitive hemagglutinin in patients with cholera due to Vibrio cholerae O1 and O0139. Clin Diagn Lab Immunol. 1997; 4(4):429-34.

279. Albert MJ, Islam D, Nahar S, Qadri F, Falklind S, Weintraub A. Rapid detection of Vibrio cholerae O139 Bengal from stool specimens by PCR. J Clin Microbiol. 1997; 35(6):1633-5.

280. Faruque SM, Ahmed KM, Abdul Alim AR, Qadri F, Siddique AK, Albert MJ. Emergence of a new clone of toxigenic Vibrio cholerae O1 biotype El Tor displacing V. cholerae O139 Bengal in Bangladesh. J Clin Microbiol. 1997; 35(3):624-30.

281. Linnerberg M, Widmalm G, Rahman MM, Jansson P-E, Holme T, Qadri F, Albert MJ. Structural studies of the O-antigenic polysaccharide from an Aeromonas caviae strain. Carbohyd Res 1996; 291:165-174.

282. Clemens J, Albert MJ, Rao M, Huda S, Qadri F, Van Loon FP, Pradhan B, Naficy A, Banik A. Sociodemographic, hygienic and nutritional correlates of Helicobacter pylori infection of young Bangladeshi children. Pediatr Infect Dis J. 1996; 15(12):1113-8.

283. Azim T, Qadri F, Ahmed S, Sarker MS, Halder RC, Hamadani J, Chowdhury A, Wahed MA, Salam MA, Albert MJ. Lipopolysaccharide-specific antibodies in plasma and stools of children with Shigella-associated leukemoid reaction and hemolytic-uremic syndrome. Clin Diagn Lab Immunol. 1996; 3(6):701-5.

284. Qadri F, Mohi MG, Chowdhury A, Alam K, Azim T, Sears C, Sack RB, Albert MJ. Monoclonal antibodies to the enterotoxin of Bacteroides fragilis: production, characterization, and immunodiagnostic application. Clin Diagn Lab Immunol. 1996; 3(5):608-10.

285. Qadri F, Mohi MG, Azim T, Faruque SM, Kabir AK, Albert MJ. Production, characterization and immunodiagnostic application of a monoclonal antibody to Shiga toxin. J Diarrhoeal Dis Res. 1996; 14(2):95-100.

286. Albert MJ, Ansaruzzaman M, Shimada T, Rahman A, Bhuiyan NA, Nahar S , Qadri F, Islam MS. Characterization of Aeromonas trota strains that cross-react with Vibrio cholerae O139 Bengal. J Clin Microbiol. 1995; 33(12):3119-23.

287. Giron JA, Qadri F, Azim T, Jarvis KJ, Kaper JB, Albert MJ. Monoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli. Infect Immun. 1995; 63(12):4949-52.

288. Qadri F, Mohi G, Hossain J, Azim T, Khan AM, Salam MA, Sack RB, Albert MJ, Svennerholm AM. Comparison of the vibriocidal antibody response in cholera due to Vibrio cholerae O139 Bengal with the response in cholera due to Vibrio cholerae O1. Clin Diagn Lab Immunol. 1995; 2(6):685-8.

289. Islam LN, Ferdous A, Azim T, Qadri F, Rahman A, Islam MS, Tzipori S. Peripheral blood granulocytes and mononuclear cell responses in monkeys with experimental shigellosis. J Diarrhoeal Dis Res. 1994; 12(2):97-102.

290. Albert MJ, Holme T, Lindberg B, Lindberg J, Mosihuzzaman M, Qadri F, Rahman MM. Structural studies of the Shigella boydii type 5 O-antigen polysaccharide. Carbohydr Res. 1994; 265(1):121-7.

291. Giron JA, Qadri F, Azim T, Jarvis KJ, Kaper JB, Albert MJ. Monoclonal antibodies specific for the bundle-forming pilus of enteropathogenic Escherichia coli. Infect Immun. 1995; 63(12):4949-52.

292. Haque MA, Qadri F, Ohki K, Kohashi O. Surface components of shigellae involved in adhesion and haemagglutination. J Appl Bacteriol. 1995; 79(2):186-94.

293. Ciznar I, Qadri F, Hoque S, Bin AA, Schultsz C, Bartkova G. Mucosal immune response in patients with dysentery. Adv Exp Med Biol. 1995; 371B:919-22.

294. Qadri F, Azim T, Hossain A, Islam D, Mondal G, Faruque SM, Albert MJ. A monoclonal antibody to Shigella dysenteriae serotype 13 cross-reacting with Shiga toxin. Adv Exp Med Biol. 1995; 371B:923-6.

295. Qadri F, Hasan JA, Hossain J, Chowdhury A, Begum YA, Azim T, Loomis L, Sack RB, Albert MJ. Evaluation of the monoclonal antibody-based kit Bengal SMART for rapid detection of Vibrio cholerae O139 synonym Bengal in stool samples. J Clin Microbiol. 1995; 33(3):732-4.

296. Clemens J, Albert MJ, Rao M, Qadri F, Huda S, Kay B, van Loon FP, Sack D, Pradhan BA, Sack RB. Impact of infection by Helicobacter pylori on the risk and severity of endemic cholera. J Infect Dis. 1995; 171(6):1653-6.

297. Azim T, Halder RC, Sarker MS, Ahmed S, Hamadani J, Chowdhury A, Qadri F, Salam MA, Sack RB, Albert MJ. Cytokines in the stools of children with complicated shigellosis. Clin Diagn Lab Immunol. 1995; 2(4):492-5.

298. Haque M, Masihur Rahman K, Azad Khan A, Hasan M, Amin Miah MR, Rahman T, Khurshed Alam AK, Qadri F. Isolation and characterization of Helicobacter pylori strains from peptic ulcer patients in Dhaka, Bangladesh. Indian J Gastroenterol. 1995; 14(4):128-30.

299. Qadri F, Chowdhury A, Hossain J, Chowdhury K, Azim T, Shimada T, Islam KM, Sack RB, Albert MJ. Development and evaluation of rapid monoclonal antibody-based

coagglutination test for direct detection of Vibrio cholerae O139 synonym Bengal in stool samples. J Clin Microbiol. 1994; 32(6):1589-90.

300. Qadri F, Azim T, Hossain A, Chowdhury A, Albert MJ. Monoclonal antibodies specific for Shigella dysenteriae serotype 13. Production, characterization, and diagnostic application. Diagn Microbiol Infect Dis. 1994;18(3):145-9.

301. Qadri F, Haque A, Faruque SM, Bettelheim KA, Robins-Browne R, Albert MJ. Hemagglutinating properties of enteroaggregative Escherichia coli. J Clin Microbiol. 1994; 32(2):510-4.

302. Albert MJ, Alam K, Ansaruzzaman M, Qadri F, Sack RB. Lack of cross-protection against diarrhea due to Vibrio cholerae O139 (Bengal strain) after oral immunization of rabbits with V. cholerae O1 vaccine strain CVD103-HgR. J Infect Dis. 1994;169(1):230-1.

303. Qadri F, Haque A, Hossain A, Albert MJ. Production of slime polysaccharides by Shigella dysenteriae type 1. Microbiol Immunol. 1994; 38(1):11-8.

304. Sayeed S, Sack DA, Qadri F. Protection from Shigella sonn infection by immunisation of rabbits with Plesiomonas shigelloides (SVC 01). J Med Microbiol. 1992; 37(6):382-4.

305. Qadri F, Azim T, Hossain A, Islam D, Mondol G, Faruque SM, Albert MJ. A monoclonal antibody to Shigella dysenteriae serotypes 13 cross-reacting with Shiga toxin. FEMS Microbiol Lett. 1993;107(2-3):343-7. Adv Exp Med Biol. 1995; 371B:923-6.

306. Albert MJ, Qadri F, Ansaruzzaman M, Kibriya AK, Haider K, Neogi PK, Alam K, Alam AN. Characterization of Aeromonas caviae antigens which cross-react with Shigella boydii 5. J Clin Microbiol. 1992; 30(5):1341-3.

307. Sayeed S, Sack DA, Qadri F. Occurrence of a large plasmid in strai of Plesiomonas shigelloides with cross-reactivity against Shigella sonnei. Indian J Med Res. 1992; 95:21-2.

308. Schultsz C, Qadri F, Hossain SA, Ahmed F, Ciznar I. Shigella- specific IgA in saliva of children with bacillary dysentery. FEMS Microbiol Immunol. 1992; 4(2):65-72.

309. Rahman MM, Qadri F, Albert MJ, Hossain A, Mosihuzzaman M. Lipopolysaccharide composition and virulence properties of clinical and environmental strains of Vibrio fluvialis and Vibrio mimicus. Microbiol Immunol. 1992; 36(4):327-38.

310. Schultsz C, Qadri F, Ciznar I, Bastkova G, Hossain SA, Wadstrom T. Binding of Shigella species to hydrophobic gels. Biologia 1992; 47:249-56.

311. Albert MJ, Ansaruzzaman M, Faruque SM, Haider K, Qadri F, Islam MM, Kibriya AK, Tzipori S. Outbreak of keratoconjunctivitis due to Salmonella weltevreden in a guinea pig colony. J Clin Microbiol. 1991; 29(9):2002-6.

312. Albert MJ, Salam A, Qadri F, Kibriya AK, Tzipori S. Simultaneous infection with multiple serotypes of Shigellae in a patient. Diagn Microbiol Infect Dis. 1991; 14(4):353-4.

313. Qadri F, Azim T, Chowdhury A, Hossain J, Sack RB, Albert MJ. Production, characterization, and application of monoclonal antibodies to Vibrio cholerae O139 synonym Bengal. Clin Diagn Lab Immunol. 1994; 1(1):51-4.

314. Haque M, Rahman KM, Khan AK, Hassan M, Miah MR, Qadri F, Akhter Q. Antigen profile of Helicobacter pylori strains isolated from peptic ulcer patients in Dhaka, Bangladesh. Bangladesh Med Res Counc Bull. 1993; 19(3):71-8.

315. Albert MJ, Ansaruzzaman M, Qadri F, Hossain A, Kibriya AK, Haider K, Nahar S, Faruque SM, Alam AN. Characterisation of Plesiomonas shigelloides strains that share type-specific antigen with Shigella flexneri 6 and common group 1 antigen with Shigella flexneri spp. and Shigella dysenteriae 1. J Med Microbiol. 1993; 39(3):211-7.

316. Islam MS, Hasan MK, Miah MA, Qadri F, Yunus M, Sack RB, Albert MJ. Isolation of Vibrio cholerae O139 Bengal from water in Bangladesh. Lancet. 1993; 342(8868):430.

317. Qadri F, Haque MA, Hossain A, Azim T, Alam K, Albert MJ. Role of Shigella dysenteriae type 1 slime polysaccharide in resistance to serum killing and phagocytosis. Microb Pathog. 1993; 14(6):441-9.

318. Haider K, Hossain A, Wanke C, Qadri F, Ali S, Nahar S. Production of mucinase and neuraminidase and binding of Shigella to intestinal mucin. J Diarrhoeal Dis Res. 1993; 11(2):88-92.

319. Albert MJ, Qadri F, Haque A, Bhuiyan NA. Bacterial clump formation at the surface of liquid culture as a rapid test for identification of enteroaggregative Escherichia coli. J Clin Microbiol. 1993; 31(5):1397-9.

320. Huq A, Parveen S, Qadri F, Sack DA, Colwell RR. Comparison of Vibrio cholerae serotype 01 strains isolated from patients and the aquatic environment. J Trop Med Hyg. 1993; 96(2):86-92.

321. Haider K, Rahman H, Hossain A, Qadri F, Bhuiyan NA. Construction of a plasmidless Shigella dysenteriae type 1 strain for genetic studies of Shigella. Bangladesh J Microbiol 1993; 85-93.

322. Qadri F, Haq S, Hossain SA, Ciznar I, Tzipori S. The association of haemagglutination and adhesion with lipopolysaccharide of Shigella dysenteriae serotype l. J Med Microbiol. 1991; 34(5): 259-64.

323. Haider K, Azad AK, Qadri F, Nahar S, Ciznar I. Role of plasmids in virulence- associated attributes and in O-antigen expression in Shigella dysenteriae type l strains. J Med Microbiol. 1990; 33(1): 1-9.

324. Qadri F, Raqib R, Husain IA, Ciznar I. Cell surface proteins from shigella dysenteriae type l. Zentralbl Bakteriol. 1990; 273(3):287-99.

325. Qadri F, Haq S, Ciznar I. Hemagglutinating properties of Shigella dysenteriae type l and other Shigella species. Infact Immun. 1989; 57(9):2909-11.

326. Sayeed S, Sack DA, Qadri F. Cross-reacting antigens between Plesiomonas shiglloides 0:17 and Shigella sonnei. Bangladesh J Microbiol 1989; 6:7-12.

327. Qadri F, Hossain SA, Ciznar I, HaiderK, Ljungh A, Wadstrom T, Sack DA. Congo red binding and salt aggregation as indicators of virulence in Shigella species. J Clin Microbiol. 1988; 26(7): 1343-8.

328. Shameem GM, Qadri F, Isolation and purification of placental type alkaline phosphatase from a seminoma. Clin Chem. 1987; 33 (2Pt 1): 248-52.

329. Qadri F. The reactive triazine dyes—their usefulness and limitation in protein purifications. Trends in Biotechnol 1985; 3:7-12.

330. Yasmin T, Qadri F. Purification of placental alkaline phosphatase by sulphate- mediated chromatography on Cibacron Blue 3G-A. J Chromatogr. 1984.19; 315:425-9.

331. Qadri F, Dean PD. The effect of nucleotide presaturation on the chromatographic behaviour of 6-phosphogluconate dehydrogenase from Bacillus stearothermophilus on immobilized triazine dyes. Biochem J.1981 1; 199(3):471-2.

332. Dean PD, Qadri F. Affinity Chromatography on Immobilized Dyes, in: Solid Phase Biochemistry: Analytical Synthetic Aspects, ed. 1981. W. H.

333. Qadri F, Dean PD. The use of various immobilized-triazine affinity dyes for the purification of 6-phosphogluconate dehydrogenase from Bacillus stearothermophilus. Biochem J. 1980; 191(1): 53-62.

334. Dean PDG, Qadri F, Jessup W, Bouriotis V, Angal S, Potuzak H, Leatherbarrow RJ, Miron T, George E, Morgan MRA. In Affinity Chromatography, INSERM, ed Egly J, 1979; 86:321-44

Fellowship and grant supportOngoing1. Ref # 065429 (Qadri)

The Wellcome Trust grant 05/01/2015 – 04/01/2019 0.60 calendar‘Epidemiological studies on typhoid fever’ £535,739

The overall aim of the grant is to provide the science to underpin the implementation of new vaccinees for the control of enteric fever in different epidemiological settings in Africa and Asia.

2. GAVI CONTRACT NO. PP45820815 09/01/2015 – 10/31/2018 1.0 calendar GAVI Cholera Vaccination Urban Slums against CH $2,854,682Targeted Vaccination of Children amongst the Urban Slums against Cholera: Evaluation of a Potentially Cost-effective and Impactful Strategy for Deploying oral Cholera Vaccine in Bangladesh

3. D-43 TW005572 (Ryan/Qadri)) /01/2011– 2/28/2019 0.40 calendarNIH/MGH $815,210Training program in vaccine development and public health The purpose of this study is train students in Mucosal Immunology and Epidemiology

4. 1R01AI103055 (Harris) 2/01/2013 – 11/30/2018 0.60 calendar Massachusetts General Hospital (MGH), USA $340,555 Innate and Early B cell Responses to Vibrio choleraeThe purpose of the study is to to obtain blood specimens and duodenal biopsies from adult participants who are vaccinated with the killed oral cholera vaccine, Dukoral®, and identify innate immune and adaptive immune responses induced by vaccination

5. 5RO1A1089894 (Fleckenstein) 12/02/2011 – 01/31/2019 0.60 calendar Washington University in St. Louis $321,842 Novel Antigen Identification for an Enterotoxigenic E. Coli Vaccine The long-term objective of this project is to identify molecular targets on the surface of enterotoxigenic E. coli that could be used in a vaccine. It combines the use of comparative genomics, transcriptome analysis, and immuno- proteomic analysis to arrive at a core set of conserved vaccine targets. Proteins which are: (1) highly conserved and (2) immunogenic will be used to vaccinate mice and examine their relative protective efficacy against ETEC.

6.R01 AI 106878 (Ryan) 04/10/2014 – 03/31/2019 1.00 calendar NIH/NIAID $398,532 O-specific polysaccharide responses and cholera

The plasma O-specific polysaccharide (OSP) specific IgA, IgG and IgM antibody response will be assessed using a standardized enzyme linked immunosorbent assay (ELISA) following natural cholera infection.

7. OPP1131107 (Qadri) 05/01/2015 – 06/30/209 0.60 calendarBill & Melinda Gates Foundation, USA $1,335,088'Determining disease burden due to enteric pathogens to estimate prevalence of enteric diseases in Bangladesh in children and adults using Taqman qPCR technology'

The purpose of this project is to carry out analyses of specimens from the two different surveillance studies, the 2% systematic surveillance of diarrheal patients at the icddr,b, as well as the nationwide surveillance as well as in selected hospitals of Bangladesh and to determine prevalence of enteric pathogens in children of different age groups as well as adults.

8. OPP1135223 (Qadri) 10/01/2015 – 09/30/2019 0.50 calendar'Control of Endemic Cholera in Bangladesh' $2,732,453The purpose of this proposal is to build a plan (including surveillance of high risk areas) and identify strategies for the introduction of OCV in Bangladesh; and identify a financing plan for the introduction of a local vaccine in Bangladesh in the short term.

9. DMID PR-140031 – Task B & D (UMB) 01/01/2016 - 02/11/2019 1.00 calendar $686,111DMID 14-0031: A phase 1 double-blinded, placebo-controlled, dose escalating study to evaluate the safety and immunogenicity of double mutant heat-labile toxin LTR192F/L211A (dmLT) from Enterotoxigenic Escherichia coli (ETEC) by oral, sublingual, or intradermal vaccination in adults residing in an endemic area.

10. DMID PR-140031 - Task-C (UMB) 05/15/2017 - 03/15/2020 1.20 calendar $624,233DMID 14-0031: A phase 1 double-blinded, placebo-controlled, dose escalating study to evaluate the safety and immunogenicity of double mutant heat-labile toxin LTR192F/L211A (dmLT) from Enterotoxigenic Escherichia coli (ETEC) by oral, sublingual, or intradermal vaccination in adults residing in an endemic area.

11. University of Oxford 11/01/2017 – 10/31/2021 1.00 calendar'Typhoid conjugate vaccine - effectiveness study $8,172,524A phase III cluster randomized trial of Typhoid Vi-Polysaccharide Conjugate Vaccine (TCV) to assess the impact of the vaccine in preventing typhoid infection among Bangladeshi children

12. OPP1171432Extended analysis-Cholera and Typhoid 11/01/2017 – 12/31/2019 0.60 calendarBill & Melinda Gates Foundation, USA $661,991

The icddr,b and IVI have collaborated on multiple research projects addressing the epidemiology of vaccines for cholera. This is in addition to each institution`s individual work on cholera and typhoid fever. To date, papers with significant global health impact been published on these

studies, yet, the papers are relatively few in number in relation to the size and richness of the data available from the studies. Computerized datasets from these projects have been cleaned, archived, and documented, and are available for analyses

13. UNICEF 2/01/2017 – 12/31/2018 1.8 calendar $488,519‘Oral Cholera Vaccination Campaign among the Unregistered Rohingya Myanmar Nationals (URMN) in Bangladesh to Assess the Effectiveness: Test-Negative Study Design'Surveillance of the Rohingya refugees in Cox’s bazaar, Bangladesh.ong Bangladeshi children