tumores neuroendocrinos club.1ppt

32
Clasificación patológica de los Tumores neuroendocrinos Harold J . Bolaños MD Patólogo Universidad del Cauca Facultad Ciencias de la Salud Departamento de Patología

Upload: haroldbolanos

Post on 09-May-2015

594 views

Category:

Health & Medicine


0 download

DESCRIPTION

Este documento contiene la clasificación actualizada de los tumores neuroendocrinos

TRANSCRIPT

Page 1: Tumores neuroendocrinos club.1ppt

Clasificación patológica de los Tumores neuroendocrinos

Harold J . Bolaños

MD Patólogo

Universidad del Cauca

Facultad Ciencias de la Salud

Departamento de Patología

Page 2: Tumores neuroendocrinos club.1ppt
Page 3: Tumores neuroendocrinos club.1ppt
Page 4: Tumores neuroendocrinos club.1ppt

Sinaptofisina

Page 5: Tumores neuroendocrinos club.1ppt
Page 6: Tumores neuroendocrinos club.1ppt
Page 7: Tumores neuroendocrinos club.1ppt

Figure 4 High-resolution CT scans showing the two distinct metastatic types of

ileal neuroendocrine tumors

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120

Page 8: Tumores neuroendocrinos club.1ppt

Table 3 Tumor markers of common use (tissue and fluid)

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120

Page 9: Tumores neuroendocrinos club.1ppt

Figure 2 Histology of digestive neuroendocrine neoplasms

according to tumor grade

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120

Page 10: Tumores neuroendocrinos club.1ppt
Page 11: Tumores neuroendocrinos club.1ppt
Page 12: Tumores neuroendocrinos club.1ppt
Page 13: Tumores neuroendocrinos club.1ppt

Table 1 Gastrointestinal neoplasms

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120

Page 14: Tumores neuroendocrinos club.1ppt
Page 15: Tumores neuroendocrinos club.1ppt
Page 16: Tumores neuroendocrinos club.1ppt
Page 17: Tumores neuroendocrinos club.1ppt
Page 18: Tumores neuroendocrinos club.1ppt
Page 19: Tumores neuroendocrinos club.1ppt
Page 20: Tumores neuroendocrinos club.1ppt
Page 21: Tumores neuroendocrinos club.1ppt
Page 22: Tumores neuroendocrinos club.1ppt
Page 23: Tumores neuroendocrinos club.1ppt
Page 24: Tumores neuroendocrinos club.1ppt
Page 25: Tumores neuroendocrinos club.1ppt
Page 26: Tumores neuroendocrinos club.1ppt
Page 27: Tumores neuroendocrinos club.1ppt
Page 28: Tumores neuroendocrinos club.1ppt

Figure 1 Molecular targeted therapy for NETs.

Basu B et al. Endocr Relat Cancer 2010;17:R75-R90

Page 29: Tumores neuroendocrinos club.1ppt

Table 2 WHO 2010 classification and suggested grading

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120

Page 30: Tumores neuroendocrinos club.1ppt

Table 4 Sequence of imaging procedures for optimal visualization

of primary tumors

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120

Page 31: Tumores neuroendocrinos club.1ppt

Figure 1 Functional characteristics of neuroendocrine cells with

relevant antigens

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120

Page 32: Tumores neuroendocrinos club.1ppt

Figure 3 Current therapeutic targets in the neuroendocrine tumor cell

Rindi, G. & Wiedenmann, B. (2011) Neuroendocrine neoplasms of the gut and pancreas: new insights

Nat. Rev. Endocrinol. doi:10.1038/nrendo.2011.120