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USF Health - Update Presented to: Research Matters at USF Health Tuesday, February 20, 2007 Abdul S. Rao, M.D, M.A, D.Phil Sr. Associate Vice President USF Health

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USF Health - Update

Presented to:

Research Matters at USF Health

Tuesday, February 20, 2007

Abdul S. Rao, M.D, M.A, D.Phil

Sr. Associate Vice President

USF Health

Facts About USF and USF Health

� 43,000+ students on four campuses

� Carnegie Foundation Classification 2005� Comprehensive doctoral with medical/veterinary� RU/VH (Research University/Very High Research Activity)

� Among 63 public universities in the U.S.� Among 95 public and private universities in the U.S.� In the State of Florida

Research Matters at USF Health

� In the State of Florida� One of three public university� One of four public and private university

� Colleges/Schools at USF Health� College of Medicine

� School of Physical Therapy & Rehabilitation Sciences� School of Basic Biomedical Sciences

� College of Nursing� College of Public Health

Commitment to make USF one of the top 50 public research universities

in the U.S.

President Judy Genshaft’s address – Fall 2004

Research Matters at USF Health

President Judy Genshaft’s address – Fall 2004

Commitment to gain membership of the Association of American

Universities (AAU)

USF Strategic Plan – 2007-2012

In NIH ranking, place USF Health COM in the top 50th percentile of U.S.

medical colleges/schools

Research Matters at USF Health

medical colleges/schools

Vice President/Dean Steve Klasko

Extramural Funding

310

164

287

255

290

144

200

250

300

350$; millions

USF USF - Health COM CON COPH

Research Matters at USF Health

164

88

116 112

144

2.6 2.7 1.7 4

29 25 19 16

133

144

120

0

50

100

150

FY 02-03 FY 03-04 FY 04-05 FY 05-06

Fiscal Years

$; millions

Date Source: USF Office of Research

Research Matters at USF Health

USF Research Cont’d…

• Molecular Medicine is ranked 49th out of 107 universities in NIH funding (FY 05-06) with $4.7m in research grants

Research Matters at USF Health

• Family Medicine is ranked 35th out of 50 universities in NIH funding (FY 05-06) with $315,181 in research grants

Graduate Programs @ USF Health

• Doctoral Programs programs:• Integrated Medical Sciences• Nursing Science• Public Health• Cancer Biology

Research Matters at USF Health

• Cancer Biology• Physical Therapy

• Master-level programs

• Certificate Programs

A Paradigm Shift at USF Health

Research matters in….

• Education– Professional– Graduate– Nursing

Research Matters at USF Health

– Nursing– Residency– Fellowships

• Clinical Practice

• Community Service

Enhance Faculty ProductivityPERFORMANCE METRICS

Accomplish Goals I & II USF Strategic Plan 2007-12

Research Matters at USF HealthResearch Matters at USF Health

INPUTS

Reorganized Basic Science

Research at USF Health COM

Research Matters at USF Health

Merged Basic Science Departments

COM Departmental Organization Structure: Pre-Merger

DEPARTMENTS

BASIC BASIC/CLINICAL CLINICAL

Medical Micro& Immunology

Biochemistry &

Pathology

Interdisciplinary

Internal Medicine Surgery

Psychiatry Pediatrics

Research Matters at USF Health

Mol. Biology

Pharmacology &Therapeutics

Physiology &Biophysics

OncologyPsychiatry Pediatrics

OB/GYN Neurosurgery

Neurology Family Medicine

Ophthalmology Anesthesiology

Radiology Otolaryngology

COM Departmental Organization Structure: Post-Merger

Molecular Pharmacology

& Physiology

Physiology &

Biophysics

Pharmacology &

Therapeutics

Molecular Medicine

Medical Microbiology

& Immunology

Biochemistry &

Molecular Biology

BASIC

Interdisciplinary

Oncology

Pathology &

Cell Biology

Pathology

Anatomy

BASIC/CLINICAL

Internal Medicine Surgery

Pediatrics Psychiatry

CLINICAL

DEPARTMENTS

Research Matters at USF Health

New Merged Departments

OB/GYN Neurology

Neurosurgery Anesthesiology

Family Medicine Ophthalmology

Otolaryngology Radiology

Signature Research Programs

Faculty, staff and students

from:• Departments

• Centers• Institutes• Colleges

Neurosciences

Cardiovascular

Research Matters at USF Health

• Colleges• Schools

at

• USF• USF Health

• Affiliate Partners

Allergy, Immunology, & Infectious Diseases

Cancer Biology

Emerging/Supporting Technologies

• Genomics and Proteomics

• Bioinformatics/Computational Biology

• Pharmacogenomics

Research Matters at USF Health

• Pharmacogenomics

• Drug Discovery and Development

• Structural Biology

• Biomedical Engineering

• Regenerative and Nano Medicine

Institute for Translational & Clinical Research @ USF Health

• Entrepreneurial..to meet the needs of today’s stakeholders and corporate partners

• “One-stop” shop for:• Investigators (USF and Non-USF Faculty)• Clinical Coordinators• Patients• Referring MD’s • Corporate Partners (pharmaceutical, biotech, medical device

Research Matters at USF Health

• Corporate Partners (pharmaceutical, biotech, medical device companies, etc.)

• Contract development, negotiation, & management services• Appropriate billing and collection services• Biostatistics and epidemiology support• Facilitate submission of protocols to the IRB’s• Education and training of students, staff, and faculty• Oversight in the proper conduct of human subject research• Data management and analysis services

↑ Translational & Clinical ResearchUSF Faculty, Residents, Staff,

and Students

• Acquisition of new knowledge

• Improved quality of patient care

Research Matters at USF Health

• Diverse therapeutic portfolio

• Recruitment & retention of quality basic

scientists, physicians, residents, students, etc.

Targeted Faculty Recruitment

Research Matters at USF Health

Recruitment

World Class Scholars…I

• Thomas Unnash, PhD– Signature Program: Global Health and AIID

– Current Institution: UAB

– Total Research Awards: $6 million; NIH ~$4.6 million

Research Matters at USF Health

million

– PhD: MIT

– Postdoctoral Fellowships: Harvard

– Status: ACCEPTED

World Class Scholars…II

• Jeffrey Gruen, MD– Signature Program: Neurosciences; Learning Disabilities

– Current Institution: Yale

– Total Research Awards: ~$1 million

– MD: Tulane

– Residency/Fellowship: Yale

– Candidate for the Rothman Chair in Learning Disabilities

Research Matters at USF Health

– Candidate for the Rothman Chair in Learning Disabilities

– His paper on the association of DCDC2 gene with reading disabilities was cited by journal Science as the Top 5 scientific breakthroughs of 2005

– Status: Under Negotiation

World Class Scholars…III

• David Hui, PhD– Signature Program: Cardiovascular; Lipid Metabolism

– Current Institution: University of Cincinnati

– Total Research Awards: ~$4.5 million (Four NIH RO1’s)

– PhD: Indiana

Research Matters at USF Health

– PhD: Indiana

– Postdoctoral Fellowship: UCSF

– Candidate for the Chair, Department of Molecular Medicine

– Status: Under Negotiation

Targeted Faculty Recruitment…I

• Concluded:

– Dr. Robert Pedowitz, Chair, Department ofOrthopedic Surgery

• Signature Program: Sports Medicine

– Dr. Min You, Associate Professor, Department ofMolecular Pharmacology and Physiology

Research Matters at USF Health

Molecular Pharmacology and Physiology• Field of Interest: Lipid Metabolism

• Signature Program: Cardiovascular Diseases

• Current Institution: Indiana University

• Two NIH RO1’s with ~$2.2 million (direct cost)

• PhD: University of Illinois, Chicago

• Postdoctoral Fellowships: Vanderbilt University and WaltherOncology Center, Indiana University

Targeted Faculty Recruitment…II

• Concluded:– Dr. Nader Rahimi, Associate Professor,

Department of Molecular Medicine• Field of Interest: Angiogenesis

• Signature Program: Cardiovascular Diseasesand Cancer Biology

Research Matters at USF Health

• Signature Program: Cardiovascular Diseasesand Cancer Biology

• Current Institution: Boston University

• Funding:– One R01 with over $200K/year in direct costs

– Two RO1’s are currently being reviewed at the NIH

• PhD: Queens University, Canada

• Postdoctoral Fellowship: Harvard University

Targeted Faculty Recruitment…III

• Concluded:– Dr. Wil Milhous

• Start date: June 1, 2007• College of Public Health: Associate Dean for Research, and

Professor, Department of Global Health• Current Position/Institution: Chief Science Officer for

Therapeutics, Walter Reed Army Institute of Research

Research Matters at USF Health

Therapeutics, Walter Reed Army Institute of Research• PhD, 1983, University of North Carolina-Chapel Hill• Other: Diplomate, American Board of Medical Microbiology;

Fellow, American Academy of Microbiology; • Editorial board, Experimental Parasitology; • 15 patents and/or invention disclosures• Reviewer, Science, Nature, New England Journal of

Medicine, Journal of Infectious Disease and 12 other publications

Targeted Faculty Recruitment…IV

• Started (April 2006):– Dr. Dennis Kyle

• Department of Global Health

• College of Public Health

• Previous Position: Deputy Director, Division of Experimental Therapeutics, Walter Reed Army Institute of Research

Research Matters at USF Health

• PhD: Clemson University, 1984

• Funding: R01: Artemisiniin-Induced Dormancy and Malaria Treatment Failure (2006-2007)

• Funding: Private: Development of New Drugs to Treat Leishmaniasis and Late Stage Sleeping Sickness and Leishmaniasis (2006-2011)

• 5 Patents awarded, 1993-2004

Targeted Faculty Recruitment…V2006-07

• Six NIH funded faculty in the basic sciences

• Two chairs of basic and clinical departments(one each)

Research Matters at USF Health

(one each)

• At least three Endowed Chairs

• Director and Endowed Chair at Shriner’sHospital for Children's

New Clinical, Education, &

Research Space

Research Matters at USF Health

Research Space

Where patient interests are put first….

�Named the Carol and Frank Morsani Center for Advanced Healthcare�196,000 Square feet�6 Stories

�8 Operating Rooms�5 Endoscopy Suites�Diagnostic Imaging�Clinical space

�Concierge level services

Centers for Advanced Healthcare - NORTH

Research Matters at USF Health

�Concierge level services�“One Stop Shopping” service line

approach �Patient Education Center�Integrated teams (primary care, specialists, holistic)

�Women’s health�Sports Medicine�Brain health�Digestive Disorders

�Pharmacy�Basic/Translational/Clinical Research

Where form follows function….

� 126,000 sq. ft.

� 7 Stories

� Clinical Space

�Diagnostic Imaging

�Office Based Procedures

�Office Visits

� Faculty Offices

Centers for Advanced Healthcare - SOUTH

Research Matters at USF Health

� Faculty Offices

� Patient Education

� Clinical Research� Concierge level services� One Stop Shopping” service

line approach (physicians, diagnostics, procedures)

� Patient Centric

� Streamlined Work flow

� $24 Million

Centerfor Advanced

Medical Learning

and Simulation

We continue with Lifelong Learning …..an

internationally unique center

Research Matters at USF Health

….translating medical advances and knowledge into improved patient care

It’s a One-of-a-Kind, World-Class Education and Research Center

� 70,000 SF Training Center

� 50,000 SF Research Center

� 350 Room, 3-Star Hotel

Research Matters at USF Health

� $70 Million in Private Funding

� USF Health to Manage Research and Training Center

� Projected Occupancy – February 2008

Where Clinical skills are simulated and practiced….

� Surgical Skills Lab – 12,000 SF� 40 Workstations & 2 OR Suites

� Simulation Center/Virtual Hospital – 5,000 SF� Emergency Room (ER)

Research Matters at USF Health

� Emergency Room (ER)� Operating Room (OR)� Intensive Care Unit (ICU)� Standard Patient Room

� Concept Development Laboratory� Prototype development for:

� Robotics� Minimally Invasive Surgery� Image-Guided Surgery� Computer-Assisted Surgery

� Center for Advanced Research

Where innovations are tested and brought to market faster…

Research Matters at USF Health

� Center for Advanced Research� 50,000 SF � Interdisciplinary Research� Translation Research

Where great opportunities exist for..

• National and international exposure of products and services

• Translating medical advances and knowledge into improved patient care

• Faster product to market

• Advanced research

• Advanced and

Research Matters at USF Health

• Advanced and comprehensive continuing education and skill development

Meeting with Pamela and Leslie Muma

Research Matters at USF Health

Date: February 13, 2007

Time: 12:30 – 2:00 pm

Location: Mise en Place

USF Health’s Goal

USF Health’s goal is to create a world class Center for

Developmental Genetics and Neonatology in Tampa which will

Research Matters at USF Health

Neonatology in Tampa which will be the destination of choice for the

advanced care of critically ill newborns

USF Health’s Goal

• To elevate the Division of Neonatology to nationalprominence through cutting edge, evidence-basedmedicine

• To further enhance comprehensive neonatalclinical care at the expanded NICU at TGH

Research Matters at USF Health

clinical care at the expanded NICU at TGH

• To bring multidisciplinary basic and translationalresearch to the bedside

• To recruit and retain outstanding physicians,scientists, fellows, students, and support staff

Pamela and Leslie Muma Endowed Chair

Research Matters at USF Health

Pamela and Leslie Muma Endowed Chair Search Committee (Proposed)

• David Keefe, MD, Chair, OB/GYN (Committee Chair)• Pamela Muma• Charles Paidas, MD, Chief, Pediatric Surgery• Patricia Emmanuel, MD, Department of Pediatrics• Jeff Krischer, PhD, Department of Pediatrics• Terri Ashmeade, MD, Chief, Neonatology• Greg Alexander, ScD, Perinatal Epidemiology• Ruben Quintero, MD, Chief, Maternal/Fetal Medicine• Deana Nelson, RN, TGH

Research Matters at USF Health

• Deana Nelson, RN, TGH• Pam Sanders, RN, Nurse Manager TGH• Tom Klein, PhD, Department of Molecular Medicine

External Consultants:• Robert Kleigman, MD, Muma Chair of Pediatrics, Medical College of Wisconsin• Charles F. Simmons, Jr., MD, Chair, Department of Pediatrics, Ahmanson Pediatric Center,

Director, Division of Neonatology and Director of NICU at Cedars-Sinai Medical Center

Ex-Officio Members:• Robert Nelson, MD, Chair, Department of Pediatrics • Abdul S. Rao, MD, MS, DPhil, Senior Associate Vice President

Pamela and Leslie Muma Endowed Chair

Timeline

Research Matters at USF Health

•New England Journal of Medicine•Pediatric Research•American Journal of Perinatology

About Diversified Search/Ray & Berndston

� Top 10 retained search firms in the United States;

� Healthcare and higher education sectors represent the most served industries;

� Exclusive U.S. partner for Ray & Berndston, the 5th largest search firm in the world with 51

Research Matters at USF Health

5th largest search firm in the world with 51 offices in the 32 countries;

� Reputation for excellence for over 32-years with consistent recognition as an industry leader of consultative retained executive search services; and

� Longstanding client relationships as evidenced by a 75 percent repeat business rate.

Select Healthcare and Higher Education Clients for SeniorExecutive, Academic and Administrative Searches

� Ascension Health

� Arizona State University

� Bowdoin College

� Carnegie Mellon University

� Children’s Hospital of Boston

� Children’s Hospital of Philadelphia

Research Matters at USF Health

� Children’s Hospital of Philadelphia

� Dana-Farber Cancer Institute

� Drexel University

� Duke University

� Georgia Institute of Technology

� Johns Hopkins University

� London Business School

� Massachusetts Institute of Technology

Select Healthcare and Higher Education Clients for Senior Executive, Academic and Administrative Searches

� Middlebury College

� MD Anderson Cancer Center

� Montefiore Medical Center

� Partners Healthcare

� University of Pennsylvania

Research Matters at USF Health

� University of Pennsylvania

� SSM Healthcare

� Stanford University

� St. Christopher’s Hospital for Children

� UPMC Health System

� Williams College

PEDIATRICS

Rothman ChairRothman ChairMuma ChairMuma ChairCMS ClinicsTGH Clinics

CRI Laboratories

School of Physical Therapy

Rothman Chair in Rothman Chair in Neonatology/Developmental PediatricsNeonatology/Developmental Pediatrics

World Class ScholarWorld Class ScholarDirector of SIPDirector of SIP

Women & Children SIP

College of Nursing

Clinical/Community

SIP - Neurodevelopment and Child Health

Research Matters at USF Health

PSYCHIATRYSilver Chair Silver Chair

Roskamp ChairRoskamp ChairChild and Adolescent Psych;

Silver CenterInstitute for Research in

Psychiatry

PUBLIC HEALTHMarrell ChairMarrell Chair

Community and Family Health;

Epidemiology and

Biostatistics; Chiles Center for Healthy Mothers and Infants

FMHICommunications

Special Ed

PsychologySocial Work

Director of SIPDirector of SIP

CABR

Community/Basic Research

Translational/Clinical Research