enzymes
TRANSCRIPT
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ENZYMES
http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gif
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Enzymes are proteinsChemical reactions need help to
get started.
Ex: A fire needs a match to get it started.
The reactants (what you start with) need help to carry out the chemical reaction to develop the products
http://www.chuckwagondiner.com/art/matches.jpghttp://plato.acadiau.ca/COURSES/comm/g5/Fire_Animation.gif
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______________ to get a chemical reaction _______________
= ________________________
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ACTIVATION ENERGY
REACTANTSPRODUCTS
ACTIVATIONENERGY
Energy requiredSTARTED
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Exergonic Reactions
Fre
e e
nerg
y
Progress of the reaction
∆G < O
EA
Figure 8.14
A B
C D
Reactants
A
C D
B
Transition state
A B
C D
Products
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___________ HELP CHEMICAL REACTIONS _______________
by ____________ the___________________________to get a chemical reaction started.
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DECREASING
Enzymes
ACTIVATION ENERGY required
HAPPEN FASTER
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Progress of the reaction
Products
Course of reaction without enzyme
Reactants
Course of reaction with enzyme
EA
withoutenzyme
EA with enzymeis lower
∆G is unaffected by enzyme
Fre
e e
nerg
y
Figure 8.15
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PROTEINS CAN BE ENZYMES
SUBSTRATE
ENZYME-SUBSTRATE COMPLEX
PRODUCTSENZYMEUnchanged& Reusable
ENZYME
Image modified from: http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gifArrow: http://www.gifanimations.com/action/ImageDisplay/1/2/11/next
ACTIVESITE
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ENZYMES _____ like a _______________
to only _________of _________.
Enzymes are ___________ by thereaction and ___________
LOCK AND KEY
REUSABLEUNCHANGED
FIT
ONE KIND SUBSTRATE
http://www.grand-illusions.com/images/articles/toyshop/trick_lock/mainimage.jpg
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FACTORS THAT AFFECT ENZYME ACTIVITY
__________ & ______________
Conditions that are TOO ACIDIC
or TOO HOT cause proteins to________ or _________
pH temperature
UNWIND DENATURE
http://www.desktopfotos.de/Downloads/melt_cd.jpg http://www.nealbrownstudio.com/adm/photo/163_nb_fried_egg.jpg
See a movieChoose narrated
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Progress of the reaction
Products
Course of reaction without enzyme
Reactants
Course of reaction with enzyme
EA
withoutenzyme
EA with enzymeis lower
∆G is unaffected by enzyme
Fre
e e
nerg
y
Figure 8.15