Nouaying Kue

BME 281

Dermagraft® is a dermal substitute that is a result of original human skin. It is a cell based tissue that is grown on a three dimensional scaffold.

A new packet, will contain cells that are important for the wound to heal.

Dermagraft is packaged in 2in x 3in rectangles.

Nanoskin is an organic fiber layered skin substitute that acts as a building block for the skin to regrow.

It is also packaged individually, for usage.

The Nanoskin is packaged in boxes of 12 packets which contain 10cm x 10cm squares of Nanoskin.

There are many dermal injuries that are treated by artificial skin.

Burns Skin deformations/abrasions Bone regeneration Ulcers Excoriations Epidermolysis Bullosa

There are approximately 150,000 amputations a year. Diabetes is the leading cause of this.

Artificial skin works by utilizing its coating to protect the affected area from bacteria.

The substitute dermis was designed so that it would not prohibit natural bodily restoration functions.

It provides a layout for the body to follow to reproduce the skin which was once there.

It regulates the humidity and gas conditions inside the wound.

As well, it does not restrict the movement of affected body parts.

Sixty-four year old female with foot ulcers from a result of Type II diabetes. Took two applications of dermagraft and four months to treat.

Fourty-one year old male, with Type I diabetes ulcer. Took two treatments and five months.

Sixty-seven year old male, with Type II diabetes took a three month weekly treatment.

Sixty-seven year old male Type II Diabetes

Depending on the brand, using artificial skin can a cheap and cost effective way to recover from ulcers, burns, etc.

The price for a box of Nanoskin is $80.00

The application process is fairly easy.

The materials will not prevent you from performing your duties.

They can be easily replaced or removed.

Patients can have a feeling of peace, by removing unsightly injuries that would prevent them from being at their peak mental state.

The treatment is fairly short, 3-5 month period.

The price per application of Dermagraft is $1,500.00

Nanoskin, may need to be replaced more often.

The transparent character of the artificial skin will be unsightly for a while.

Researchers are looking to further develop the uses of artificial skin to target more diseases, such as skin cancer.

Looking to incorporate nano-technology to help speed up the healing process.

Wider array of usage, such as on prosthetics.

For large areas, sensors are to be placed on the substitute skin.

More affordable prices for treatments.

"Bionano Future." Bionano Future. N.p., n.d. Web. 12 Oct. 2012. <http://www.bionanofuture.com/index.html>.

Guan, Guoping. "Scaffolds Decorated by In Vivo Environment Improve Cell Proliferation and Wound Healing." Millennium Web Catalog. N.p., n.d. Web. 12 Oct. 2012. <http://0-ieeexplore.ieee.org.helin.uri.edu/xpl/articleDetails.jsp?tp=>.

"InnovatecsCo." InnovatecsCo. N.p., n.d. Web. 12 Oct. 2012. <http://www.innovatecsco.com/>.

Kemmerrer, S. V. "Dermagraft Scale-up Case Study." Millennium Web Catalog. N.p., n.d. Web. 12 Oct. 2012. <http://0-ieeexplore.ieee.org.helin.uri.edu/xpl/articleDetails.jsp?tp=>.

Morgan, J. R. "Growth Factor Delivery from Genetically Modified Skin Grafts." Millennium Web Catalog. N.p., n.d. Web. 12 Oct. 2012. <http://0-ieeexplore.ieee.org.helin.uri.edu/xpl/articleDetails.jsp?tp=>.

"Wound Care Dressings." Wound Care Dressings. N.p., n.d. Web. 12 Oct. 2012. <http://feetdoc.com/wound_care_dressings.html>.