lp mg glande salivare majore esofag stomac 2016

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 1/61

GLANDELE SALIVARE MAJORE

ESOFAGSTOMAC

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 2/61

CAPSULA: ţes. conj. densSTROMA: - septe conjunctivo-vasculare,

- reţea de fibre de reticulină şi capilarePARENCHIMUL: glande tubulo-acinoase compuse

•Porţiunea sere!oare: ainii sere!ori : seroşi, mucoşi şi micşti•Porţiunea e"re!oare: ana#e#e e"re!oare

 – In!ra#o$u#are: ducte intercalare Boll, canale striatePfluger 

 – In!er#o$u#are – In!er#o$are – Cana#u# %rini%a#

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 3/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 4/61

 Acinul seros

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 5/61

 Acinul mucos

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 6/61

 Acinul mixt

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 7/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 8/61

tructura parenc!imului glandelor salivare

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 9/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 10/61

"uct intercalar 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 11/61

#anal striat

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 12/61

"ucte striate

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 13/61

#anal interlobular 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 14/61

#anal interlobar 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 15/61

#anal excretor principal

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 16/61

$landa parotidă

%&

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 17/61

$landa parotidă

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 18/61

$l b dib l ă

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 19/61

$l. submandibulară

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 20/61

$landa submandibulară

'(

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 21/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 22/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 23/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 24/61

Gl d bli lă

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 25/61

Glanda sublinguală

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 26/61

$landa sublinguală

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 27/61

ESOFAGUL

 – MUCOASA

 – SU&MUCOASA – MUSCULARA – ADVENTI'IA

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 28/61

ecţiune transversalăecţiune transversală:: lumenul esofagului estelumenul esofagului este stelat stelat  --  pliuri pliuri

longitudinale ale mucoasei longitudinale ale mucoasei  -- dispar ladispar latrecerea bolului alimentar trecerea bolului alimentar 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 29/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 30/61

() MUCOASA• E%i!e#iu# *e su%ra+aţ,: 

epiteliu pavimentos stratificatnekeratinizat 

• Corion #a.ina %ro%ria/ – Ţesut conjunctiv lax 

 – Foliculi limfoizi 

 – Glande cardiale• )ocali*are: porţiunile iniţiale

şi terminale• ecreţie de mucus neutru

• Musu#ara .uoasei - fibre musculare netede 

dispuse :  - iniţial numai longitudinal

- apoi pe două straturi:  • intern circular

• extern longitudinal

 - se +ngroaşă progresiv spre cardie

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 31/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 32/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 33/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 34/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 35/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 36/61

0 SU&MUCOASA

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 37/61

0) SU&MUCOASA

• esut conjunctiv mai dens

• ase sanguine şi limfatice• ervi : plexul nervos Meissner • esut limfoid difu* sau nodular 

• Glande esofagiene propriu-zise

 – $l. tubulo-acinoase compusede tip mucos – /ucus slab acid – "uctul excretor traversea*ă

mucoasa - se desc!ide +nlumenul esofagului

Elasticitatea submucoasei permitedisparitia pliurilor in timpuldeglutitiei.

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 38/61

1 MUSCULARA

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 39/61

1) MUSCULARA • ' straturi de fibre musculare:  intern - circular  

extern- longitudinal   0ntre straturile de fibre musculare -

plexul mienteric Auerbac!

• 1/3 superioară - fibremusculare striate• 1/3 mijlocie - amestec de fibre

musculare striate şi netede• 1/3 inferioară - fibre

musculare netede

 – 1ntern: circular  – 2xtern: longitudinal

2 ADVENTI'IA

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 40/61

2) ADVENTI'IA 

• Ţesut conjunctiv lax 

• Vase sanguine şi nervi 

• Paniculi de celule adipoase

STOMACUL

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 41/61

STOMACUL• Or3an cavitar musculo -

glandular  Anatomic:

• Regiune cardială• Regiune fundică

• Regiune pilorică

  3istologic:• 2 !unii:

 – ucoasă – !ubmucoasă – usculară – !eroasă peritoneală

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 42/61

() TUNICA MUCOAS4

• "piteliu de suprafa#ă

• "piteliu glandular • $orion• usculara mucoasei 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 43/61

• EPITELIUL DE SUPRAFA'4:simplu cilindric monomorf 

• MO:- celule +nalte, cilindrice,

dispuse pe un singur r4nd

- nucleul ovoid, situat ba*al5 n !E citoplasma apical" #

aspect spumos, vacuolar 

ecretă mucus alcalin 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 44/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 45/61

-gl.tubulare simple sauramificate,situate in

corion

6ormate din:

 – Is!.

 – G5!

 – Cor%u# 3#an*ei

G%&'("%" )*'(+$" 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 46/61

CorpIstm

Gât 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 47/61

+stmul  : - celule 7 epiteliul de suprafaţă- celule de re*ervă - rol +n regenerare 

G,tul  coletul.:  &. $"%*%" *$0 - "2+$"  &*+%+&R".4

$  cel cubice8 neregulate, mici  - con inț  granule de mucus acid 

  -secreta si enzime ptdipeptide

  5.  $"%*%" (" R"6"R789nediferenţiate sau celulele stemlocali*are:  - g4tul glandei

- istm

C # # * i

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 48/61

• Cor%u# 3#an*ei:a. #elule principaleb. #elule parietale

c. #elule enteroendocrine

a) #2);)2)2 <=1#1<A)29>1/?$22,

 A"2)?/?=62, @A>?61)2 

-  /ai numeroase profund- ecretăcomponenta enzimatic" asucului gastric

MO: 

• celule piramidale sau cilindrice• delimitea*ă lumenul glandei• limitele celulare mai şterse• nucleul: eucrom, nucleolat

• citoplasma: +n 32 granulară, ba*ofilă

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 49/61

b. #2);)2)2 <A=12A)2 9A#1"?61)2, "2)?/?=62

• umeroase superficial• 6ormă piramidală• u ajung +n lumen-

canalicul intercelular 

• ecretă: 3#l, factorulintrinsec #astle

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 50/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 51/61

CELULELE ENTEROENDOCRINE APUD SED/

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 52/61

) CELULELE ENTEROENDOCRINE APUD sau SED/

 – ituate printre celulele epiteliale ale

mucoasei gastrice şi intestinale – ecretă %ormoni peptidici &i aminebiogene

 – !E# nu se eviden'iaz" (ecesit" impregn"ri argentice

 – unt situate pe m.b., nu ajung n lumen –  0n citoplasmă: granule delimitate de

membrane – %ormoni 

 – ipuri:  argentafine: conţin granule ce reduc direct

 Ag?B

  argirofile: se impregnea*ă cu Ag ?Bnumaidupă o prealabilă tratare cu substanţereducătoare

  enterocromafine: se colorea*ă cu bicromatde potasiu

  CORIONUL MUCOASEIGASTRICE

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 53/61

GASTRICE• conţine glandele gastrice• este redus, dispus interglandular

• #esut conjunctiv lax  cu :  fibre : colagen şi reticulină  celule: fibroblaste, /f, lf,

plasmocite, mastocite, </,mici foliculi limfoi*i, rare fibremusc netede

MUSCULARA MUCOASEI 

• fibre musculare netede• dispuse +n general +n ' straturi: intern circularextern longitudinal  

0) TUNICA SU&MUCOAS4

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 54/61

0) TUNICA SU&MUCOAS4 • 'esut conjunctiv mai dens• vase sanguine şi limfatice•  plexul nervos eissner  

1) TUNICA MUSCULAR4 • f. musc. netede dispuse +n 3 straturi • oblic intern  - e bine definit numai la

cardie • mijlociu circular   – mai pronunţat +n reg  pilorului, unde formea*ă sfincterul piloric

• extern longitudinal  mai evident +n

regiunea corpului stomacului

• 0ntre stratul mijlociu circular şi externlongitudinal se află plexul mienteric

 &uerbac9 

• 2 SEROASA PERITONEAL4

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 55/61

2) SEROASA PERITONEAL4 tunica externă a stomacului

  6ormată dintr-un :• mezoteliu 9epiteliu simplu pavimentos• 'esut conjunctiv subseros 

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 56/61

Mucoasa

mm

Submucoasa

Musculara ext.

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 57/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 58/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 59/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 60/61

8/16/2019 Lp Mg Glande Salivare Majore Esofag Stomac 2016

http://slidepdf.com/reader/full/lp-mg-glande-salivare-majore-esofag-stomac-2016 61/61