curriculum vitae (1) personal data: dr. mohamed farouk...

CURRICULUM VITAE

(1) PERSONAL DATA:

Name : Dr. Mohamed Farouk Elshal

Current position : Professor of Biochemistry, Molecular Biology

Department, Genetic Engineering and

Biotechnology Research Institute, University of

Sadat City, Egypt

Linked In : https://www.linkedin.com/in/prof-mohamed-

farouk-elshal-a9b3b926

Google Scholar : https://scholar.google.com/citations?user=yOwFHk0AAAAJ&hl=en

Date of birth : 23 / 02 / 1971

Place of birth : Mansoura – Egypt

Marital status : Married

E-mail : [email protected]

Tel : (+2) 0502349040

Mobile : (+2) 01021279933 / 0114885910

(2) EDUCATOIN

1988-1992 B.Sc. in Chemistry, Faculty of Science - Mansoura University - EGYPT

1992-1993 Diploma in Computer System-Analysis and Software Programming,

Computer Center, Mansoura University – EGYPT

1993-1996 M.Sc. in Biochemistry, “Quantitative Analysis of Cellular DNA-Content

using Flow Cytometry“. Faculty of Science, Mansoura University – EGYPT

1997-2001 Ph.D. in Biochemistry and Molecular biology, “Utilization of Flow

Cytometry in the Assessment of Genetic Abnormalities in gastrointestinal

disorders“. Faculty of Science, Mansoura University – EGYPT

(3) WORK EXPERIENCE:

1992-1995 Research Assistant, Chemistry Department, Mansoura University, Egypt.

1995-2000 Clinical Biochemistry specialist; Flow cytometry unit, Biotechnology Research

Department, Gastroenterology Center, Mansoura University – Egypt.

2000-2001 Assistant Lecturer of Biochemistry, Genetic Engineering and Biotechnology

Research Institute (GEBRI), Menoufiya University – Egypt.

2001–2006 Lecturer of Biochemistry, Molecular Biology Department, (GEBRI), Menoufiya

University – Egypt.

2006-2008 Assistant Professor of Biochemistry at Molecular Biology Department, Head of

Flow Cytometry Unit, Genetic Engineering And Biotechnology Research Institute

(GEBRI), University of Sadat City – Egypt.

Mohamed Farouk Elshal, Ph.D.

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2008-2015 Associate Professor at Biochemistry Department, Faculty of science, King

Abdulaziz University, Jeddah, KSA.

2015-till now Professor of Biochemistry at Molecular Biology Department, Head of Flow

Cytometry Unit, Genetic Engineering And Biotechnology Research Institute

(GEBRI), University of Sadat City – Egypt.

(4) INVITED PROFESSIONAL APPOINTMENTS

2001-2004 Lecturer of Immunology, Zoology Department, Faculty of Science,

Menoufiya University – Egypt.

2006- 2007 Visiting Assistant Professor of Biochemistry, Biochemistry Division,

Chemistry Department, Faculty of Science, Mansoura University-

Egypt.

2008-2015 Visiting Associate Professor of Biochemistry, Biochemistry

Department, Faculty of Science, King Abdulaziz University, Jeddah,

KSA.

(5) POST-DOCTORAL FELLOWSHIP:

2004-2006 Post-Doctoral Research Fellow, National Heart, Lung, and Blood

Institute, National Institutes of Health, Bethesda, Maryland, USA.

(6) WORKSHOPS AND FACULTY TRAINING COURSES:

1. Computer Sciences and software programming, Computer Center, Mansoura

University 1/2/1992 to 4/2/1993.

2. Flow Cytometry and imaging techniques Training Course, Ain Shams University –

Cairo, Egypt from 21-23 October 1998.

3. Applications of Flow Cytometry in Clinical Practice Training Course, Cairo

University, National Cancer Institute – Cairo, Egypt, from 13-18 October 1998.

4. “Teaching Staff Preparation Course”, Faculty of Education, Menoufiya University,

Egypt. 2000

5. “Faculty & Leadership Development Project training courses” FLDP-project -

Minoufiya University, Feb. 2006 to June 2006.

6. “Faculty & Leadership Development Project training courses”, Sadat City University,

Egypt from July to August 2015.

(7) RESEARCH AND DEVELOPMENT

1. Head of Flow Cytometry Research Unit, at GEBRI, Sadat City University to assist

researchers and postgraduate students.

2. Cofounder of Immunology Unit, at King Fahd Medical Research Center, King

Abdulaziz University, Jeddah – KSA.


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3. Cofounder of Stem Cells Research Unit, at King Fahd Medical Research Center,

King Abdulaziz University, Jeddah – KSA.

(8) PUBLICATIONS:

1. Abdel-Moneim M. Osman, Huda M. Al-Kreathy, Amal Al-Zahrani, Osama A. Ahmed,

Wafaa S. Ramadan, Mohamed F. ElShal, Samir E. Al-Harthi, Ahmed S. Ali and

Lateef M. Khan. Enhancement of Efficacy and Reduced Toxicity of Cisplatin

Through Self Nanoemulsifying Drug Delivery System (SNEDDS). Int. J.

Pharmacol., 2017, DOI: 10.3923/ijp.2017.

2. Mohamed SA, Elshal MF, Kumosani TA, Aldahlawi AM, Basbrain TA, Alshehri FA,

Choudhry H. L-Asparaginase Isolated from Phaseolus vulgaris Seeds Exhibited

Potent Anti-Acute Lymphoblastic Leukemia Effects In-Vitro and Low

Immunogenic Properties In-Vivo. International Journal of Environmental

Research and Public Health. 2016 Oct 14;13(10):1008.

3. Elshal MF, Aldahlawi AM, Saadah OI, McCoy JP. Expression of CD200R1 and its

ligand CD200 on T-helper lymphocytes of pediatric patients with ulcerative

colitis and Crohn's disease. Clinical Laboratory 2016,62(8) (DOI:

10.7754/Clin.Lab.2016.151231).

4. Foda AA, Zalata KR, Elshal MF. Genetic dissimilarity between primary colorectal

carcinoma and their lymph node metastases: Ploidy, p53, Bcl-2 and c-myc

expression. Pathology. 2016 Feb 1;48:S124.

5. Mohamed F. Elshal, Kaleemuddin M., Alia M. Aldahlawi, Omar Saadah, J. Philip

McCoy. Altered expression of CD200R1 on dendritic cells of patients with

inflammatory bowel diseases: in silico investigations and clinical evaluations.

BMC Genomics 2016, 17(Suppl 6):P29.

6. Mohamed M. Abdel-aziz, Mohamed F. Elshal, Aymn T. Abass, Sherif El-Kafrawy,

Sameera Ezzat, Mohamed Abdel-Wahab A. Comparison of AFP-L3 and p53

antigen concentration with alpha-fetoprotein as serum markers for hepatocellular

carcinoma. Clin Lab. 2016;62(6):1121-9.

7. Mohamed SA, Elshal MF, Kumosani TA, Mal AO, Ahmed YM, Almulaiky YQ, Asseri

AH, Zamzami MA. Heavy Metal Accumulation is Associated with Molecular

and Pathological Perturbations in Liver of Variola louti from the Jeddah Coast of

Red Sea. Int J Environ Res Public Health. 2016 Mar 21;13(3). pii: E342.

8. Alia M. Aldahlawi, Mohamed F. Elshal, Laila A. Damiaiti, Laila H. Damanhori, Sami

M. Bahlas. Analysis of CD95 and CCR7 expression on circulating CD4+

lymphocytes revealed disparate immunoregulatory potentials in systemic lupus

erythematosus. Saudi Journal of Biological Sciences, Volume 23, Issue 1,

January 2016, Pages 101–107.

9. Zalata KR, Elshal MF, Foda AA, Shoma A. Genetic dissimilarity between primary

colorectal carcinomas and their lymph node metastases: ploidy, p53, bcl-2, and

c-myc expression—a pilot study. Tumor Biology. 2015 Aug 1;36(8):6579-84.


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10. Osman, A. M., Al-Zahrani, A., Al-Harthi, S. E., El-Hanafy, A. A., Elashmaoui, H. M.,

& Al-Kreathy HM, Ramadan WS, Elshal, M. F. Enhancement of efficacy and

reduced toxicity of cisplatin through self nanoemulsifying drug delivery system

(SNEDDS). Molecular Medicine Reports. (In press).

11. Elshal MF, Aldahlawi AM, Saadah OI, McCoy JP. Reduced Dendritic Cells Expressing

CD200R1 in Children with Inflammatory Bowel Disease: Correlation with Th17

and Regulatory T Cells. Int J Mol Sci. 2015 Dec 4;16(12):28998-9010.

12. Rasha M. Saleh, Walaa F. Awadin, Reham A. El-Shafei, Yousef Y. Elseady, Faheim E.

Wehaish and Mohamed F. Elshal. Cardioprotective role of tadalafil against

cisplatin-induced cardiovascular damage in rats. European Journal of

Pharmacology. Eur J Pharmacol. 2015 Sep 14. pii: S0014-2999(15)30247-8. doi:

10.1016/j.ejphar.2015.09.015.

13. Saleh A. Mohamed, Mohamed F. Elshal, Taha A. Kumosani, and Alia M. Aldahlawi.

Purification and Characterization of Asparaginase from Phaseolus vulgaris

Seeds, Evidence-Based Complementary and Alternative Medicine, Volume 2015

(2015), Article ID 309214

14. Murad HA, Habib H, Kamel Y, Alsayed S, Shakweer M, Elshal M. Thearubigins

protect against acetaminophen-induced hepatic and renal injury in mice:

biochemical, histopathological, immunohistochemical, and flow cytometry

study. Drug Chem Toxicol. 2015 Aug 3:1-9.

15. Zalata, K. R., Elshal, M. F., Foda, A. A., & Shoma, A. (2015). Genetic dissimilarity

between primary colorectal carcinomas and their lymph node metastases: ploidy,

p53, bcl-2, and c-myc expression-a pilot study. Tumour Biol. 2015

Aug;36(8):6579-84. doi: 10.1007/s13277-015-3353-y

16. Alia M. Aldahlawi, Mohammed F. Elshal, Fai T. Ashgan, Sami Bahlas, Chemokine

receptors expression on peripheral CD4-lymphocytes in rheumatoid arthritis:

Coexpression of CCR7 and CD95 is associated with disease activity, Saudi

Journal of Biological Sciences, Volume 22, Issue 4, July 2015, Pages 453–458.

17. Osman AM, Telity SA, Damanhouri ZA, Al-Harthy SE, Al-Kreathy HM, Ramadan WS,

Elshal MF, Khan LM, Kamel F. (). Chemosensitizing and nephroprotective

effect of resveratrol in cisplatin -treated animals. Cancer Cell Int, 2015, 15, 6.

doi: 10.1186/s12935-014-0152-2

18. Osman, A. M., Al-Malki, H. S., Al-Harthi, S. E., El-Hanafy, A. A., Elashmaoui, H. M.,

& Elshal, M. F. (2015). Modulatory role of resveratrol on cytotoxic activity of

cisplatin, sensitization and modification of cisplatin resistance in colorectal

cancer cells. Mol Med Rep. doi: 10.3892/mmr.2015.3513.

19. Mohamed F. Elshal, Alia M. Aldahlawi, Arwa A. Zehairy. Studying modulatory

effects of Prostaglandin E2 on dendritic cells-induced apoptosis by breast cancer

cells. Life Sci J 2014;11(10):155-162.

http://www.ncbi.nlm.nih.gov/pubmed/26690123


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20. Mohamed F. Elshal, Taha A. Kumosani, Essam I. Azhar, Alia M. Aldahlawi.

Quantification of circulating endothelial and progenitor cells as biomarkers for

dengue virus infection. Life Sci J 2014;11(10):250-256.

21. Faheim E. Wehaish, Yousef Y. Elseady, Rasha M. Saleh and Mohamed F. Elshal.

Molecular and Immunohistochemical Evidences for Cardiovascular Damage in

Addition to Renal Toxicity of Cisplatin in Rats. Life Sci J 2014;11(6):1-8

22. Aldahlawi AM, Elshal MF: Differentiation of Monocyte Isolated from Leukocyte

Depletion Filters into Immature Dendritic Cells Resistant to Stimulation with

Lipopolysaccharide. Life Science Journal 2013;10(4): 2542-2547.

23. Mohamed F. Elshal, Abdulrahman L. Almalki, Hussein K Hussein and Jalal A. Khan:

Synergistic antiosteoporotic effect of Lepidium Sativum and alendronate in

glucocorticoid-induced osteoporosis in Wistar rats. Afr J Tradit Complement

Altern Med. 2013; 10(5):267-273.

24. Abdel-MoneimM Osman, Ohoud M Al-Orabi, Mohamed F ElShal, Wafaa Saad El-

Din, Mohamed N. Alaama, Huda M. Al-Kerathy, ZoheirA Damanhouri and et

al. Chemosensetizing and cardioprotective effects of resveratrol in doxorubicin-

treated animals. Cancer Cell International 2013, 13:52 doi:10.1186/1475-2867-

13-52

25. Elshal, Mohamed F.; Bernawi, Amna E.; Al-Ghamdy, Maryam A.; et al. The

association of bone mineral density and parathyroid hormone with serum

magnesium in adult patients with sickle-cell anaemia, Archives of Medical

Science Volume: 8 Issue: 2 Pages: 270-276 Published: APR 2012. DOI:

10.5114/aoms.2012.28554.

26. Abdel-Moneim M Osman, Hadeel M Bayoumi, Sameer E Al-Harthi, Zoheir A

Damanhouri and Mohamed F ElShal. Modulation of doxorubicin cytotoxicity

by resveratrol in a human breast cancer cell line. Cancer Cell International 2012,

12:47. DOI:10.1186/1475-2867-12-47.

27. Elshal MF, Kumosani TA. Abulnaja KO. Influence of defatted flaxseed diet on insulin

sensitivity, vascular permeability and lipid profile in a rat model of type 2

diabetes mellitus. Journal of Medicinal Plants Research, 2012 Vol. 6(11):2188-

2193.

28. Damanhouri. L H., Al-Sakkaf. K.A, Elshal. M.F. The relationship between

Erythropoietin and adiponectin and the inflammatory cytokines. Life Sc. J. 2012,

9(4):5121-27.

29. Mohamed F. Elshal, Mohamed Abdel Salam and Jalaluddin A. Khan. n vitro

cytotoxicity and induction of apoptosis by multiwalled carbon nanotubes in

human peripheral lymphocytes: Correlation with physicochemical properties.

African Journal of Biotechnology Vol. 11(52), pp. 11455-11462, 28 June, 2012.

DOI: 10.5897/AJB11.4082.


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30. Abu-Zinadah OA, Hussein HK, Elshal MF and Elnaggar MH. Effect of excess dietary

copper on proliferation and differentiation of the proerythroblasts and

erythrocytes in rats. African Journal of Biotechnology, 2012 Vol. 11 (22):6187-

6191.

31. Maha M. Al-Bazi, Mohamed F. Elshal, Samir M. Khoja. Reduced coenzyme Q10 in

female smokers and its association with lipid profile in a young healthy adult

population. Arch Med Sci 2011;7,6:948-954. DOI: 10.5114/aoms. 2011.26605.

32. El-Far, Mohamed; Elshal, Mohamed; Refaat, Manar; et al.Antitumor activity and

antioxidant role of a novel water-soluble carboxymethyl chitosan-based

copolymer. Drug Development and Industrial Pharmacy Volume: 37:1481-1490

Published: DEC 2011. DOI:10.3109/03639045.2011.587430.

33. Jalal JA, Elshal MF, Qari MH, Al-Gamdy MA, Bernawi AE. Hypoparathyroidism and

hypocalcemia in sickle cell disease: correlation with bone turnover markers and

bone mineral density. Journal of Appplied Hematology 2011 (2): 34-40.

34. El-Far M, Elshal M, Refaat M, El-Sherbiny IM. Antitumor activity and antioxidant role

of a novel water-soluble carboxymethyl chitosan-based copolymer. Drug Dev

Ind Pharm. 2011 Dec;37(12):1481-90.

35. Jalal JA, Kumosani TA, Elshal MF: Elucidation of the possible causes in some regions

of Saudi Arabia using biochemical, microbiological, toxicological and

immunological approaches. KAU Science Bulletin, JKAU: Sci., 2010 Vol. 22

No. 1, pp: 225-238; DOI: 10.4197 / Sci. 22-1.15 2010.

36. El-Far M, Elshal MF, Bondock S, Refaat M. Preclinical biochemical studies using a

novel 5-aminolevulinic acid ester derivative with superior properties for

photodynamic therapy of tumors. International Journal of Medicine and Medical

Sciences Vol. 1(7) pp. 278-287, July, 2009.

37. Elshal MF, Abdelaziz A, Abbas A, Mahmoud K, Fathy H, Mongy SE, El-Basyuoni S,

Ahmed H, McCoy P. Quantification of circulating endothelial cells in peripheral

blood of systemic lupus erythaematosus patients: a simple and reproducible

method of assessing endothelial injury and repair. Nephrol Dial Transplant.

Nephrol Dial Transplant. 2009 May;24(5):1495-9.

38. Elshal MF, El-Sayed IH, Elsaied MA, El-Masry SA, Kumosani TA. Sperm head

defects and disturbances in spermatozoal chromatin and DNA integrities in

idiopathic infertile subjects: Association with cigarette smoking. Clin Biochem.

2009 May;42(7-8):589-94.

39. Kumosani TA, Elshal MF, Al-Jonaid AA, Abduljabar HS. The influence of smoking on

semen quality, seminal microelements and Ca(2+)-ATPase activity among

infertile and fertile men. Clin Biochem. 2008 41(14-15):1199-203.


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40. Elshal MF, Khan SS, Raghavachari N, Takahashi Y, Barb J, Bailey JJ, Munson PJ,

Solomon MA, Danner RL, McCoy JP Jr. A unique population of effector

memory lymphocytes identified by CD146 having a distinct immunophenotypic

and genomic profile. BMC Immunol. 2007 Nov 13;8:29.

41. Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide

D, Combs CA, Hall G, Zhang J, Raffeld M, Rogers TB, Stetler-Stevenson W,

Frank JA, Reitz M, Finkel T. Human mesenchymal stem cells exert potent

antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med. 2006 May

15; 203(5):1235-47.

42. Elshal MF, McCoy JP. Multiplex bead array assays: Performance evaluation and

comparison of sensitivity to ELISA. Methods. 2006 Apr;38(4):317-23.

43. El-Saied MA, Abdelaziz AM, Elkholy AM, Elshal MF: Effect of PUFA and NB-UVB

on the profiles of activated T-Lymphocytes in peripheral blood of patients with

Psoriasis Vulgaris. Egypt. J. Derm. Androl. 2006 26 (2): 65-74.

44. M A Elsaied, M F Elshal, N M Dawoud, I H El-Sayed, S El-Masry: Lipid Peroxidation

and Antioxidant Enzymes in Infertile Men: Correlation with Sperm Chromatin

Structure Assay. J. Pan-Arab League of Dermatologists Vol. 17, No. 1, February

2006

45. Elshal MF, Khan SS, Takahashi Y, Solomon MA, McCoy JP. CD146 (Mel-CAM), an

Adhesion Marker of Endothelial Cells, is a Novel Marker of Lymphocyte Subset

Activation in Normal Peripheral Blood. Blood. 2005 Oct 15;106(8):2923-4.

46. M A Elsaied, E A Farag, M F Elshal and Y E Youssef. Sperm Chromatin Structure

Assay in Varicocele Patients. J. Pan-Arab League of Dermatologists Vol. 16,

No. 1 : 141-149, February 2005

47. M. F. Elshal, J P McCoy. The detection of circulating angiogenic and vasculogenic

cells by flow cytometry. J. Clin. Ligand Assay 2004; 3:163-169.

48. M. F. Elshal, Y. Takahashi, S. Chakrabarti, R. Srinivasan, D. Suffredini, T. Igarashi, S.

Solomon, A. Lundqvist, A. J. Barrett, J. P. McCoy, Jr, and Richard Childs.

Complex Alterations in Serum Cytokines and Increased Il-4 Levels Characterize

Patients Developing Chronic Thrombocytopenia after Allogeneic Hematopoietic

Cell Transplantation. Blood, Nov 2004; 104: 4985.

49. Moustafa Ahmed El-Saied, Hanan Fathy and M F ElShal, Flow Cytometric Study of

The Effect Of Narrow-band UVB On Epidermal Cell Cycle and Ki67 Antigen

Expression in Chronic Plaque Psoriasis. J. Pan-Arab League of Dermatologists

Vol. 15, No. 1:81-90 , February 2004.

50. Elshal MF, Elsayed IH, El Kady IM, Badra G, El-Refaei A, El-Batanony M, Hendy

OM. Role of concurrent S. mansoni infection in H. pylori-associated gastritis: a


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flow cytometric DNA-analysis and oxyradicals correlations. Clin Chim Acta.

2004 16;346(2):191-8.

51. El-khawaga OA, Salem TA, Elshal MF. Protective role of Egyptian propolis against

tumor in mice. Clin Chim Acta. 2003 Dec;338(1-2):11-6.

52. M F. El-Refaei, T A. Salem, M.F.Elshal, and M Othman: Tannic acid potentially

inhbits tumor growth, raises survival of mice bearing syngeneic tumor. Eg. J.

Biochemistry 2003; 21:139-155.

53. S. A. Riad, A. A. Hemeida, M Osman, M.F. Elshal. Probiotic effects on gene

expression, DNA content and cell proliferation in bovans-white laying hens.

Egyptian J. Genet. Cytol., 32:317-339, July 2003.

54. M. F. Elshal, H A. Ismael, A Al-Hendy, and K El Halfawy: Heterogeneity of

spermatozoal dna in infertile men and its relationship to sperm motility and

semen quality. Eg. J. of Laboratory Medicine 2002, 14:51-64.

55. M. F. Elshal, Ibrahim H. El-sayed and Khalil El Halfawy: The Chromatin Structure

And In-Situ Denaturation Of Nuclear Dna In Sperms Of Infertile Men:

Correlation With Oxidative Stress. Eg. J. Biochemistry 2002; 235-250.

56. M Abdel-Wahab, A Abo-Elenein, O Fathy, N Gadel-Hak, M.F. Elshal, A Yassen, A

Sultan, and F. Ezzat: Does Cholecystectomy Affect Antral Mucosa? Endoscopic,

Histopathologic and DNA Flow Cytometric Study. HepatoGastroenterology

47:621-625; 2000.

57. M Abdel-Wahab, A.M. Attalah, M.F. Elshal, M.Abdel-Raouf, K.R.Zalata and F. Ezzat:

Cellular Proliferation And Ploidy of the Gastric Mucosa: The Role of

Helicobacter Pylori. Hepato-Gastroenterology 44:880-885; 1997.

58. A.M.Attalah, M.Abdel-Wahab, M.F. Elshal, K.R.Zalata, and F. Ezzat: Apoptosis in

Chronic Gastritis: Evaluation of the Gastric mucosa by DNA flow cytometry and

the Expression of the High Molecular Weight Cytokeratin. Hepato-

Gastroenterology 43:1305-1312; 1996.

59. M Abdel-Wahab, A.M. Attalah, M.F. Elshal, I Eldousoky, K.R.Zalata, N Gadel-Hak,

and F. Ezzat: Correlation between endoscopy, histopathology and DNA flow

cytometry in patients with gastric dyspepsia. Hepato-Gastroenterology 43:1313-

1320, 1996.

60. M. Attalah, H. G. Osman, M. F. Elshal, K. R. Zalata and M. Abdel-Wahab:

Quantitative analysis of cellular DNA content using Flow Cytometry: Evaluation

of the Biochemical Significance of Cellular DNA, serum Gastrin abnormalities

in Peptic Ulcer Diseases. Mans. Science Bulletin, 23:37; 1996.


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(9) PATENTS

61. El-Far M.A., Elshal M. & El-Sherbiny I.M. (Dec. 2007). Chemically modified chitosan

as efficient anticancer agent. (UK Patent: GB-2-454-221-A).

(10) Abstracts and Posters:

62. Mohamed F. Elshal: Role of the Expression CCR7+CCR5+ CX3CR1+ CD95+/- Cells

in the Peripheral Blood Lymphocytes in Systemic Lupus Erythematous Patients.

15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27

Aug, 2013. Poster.

63. Mohamed F. Elshal: Impact of Systemic Lupus Erythematosus on Chemokines

Expression and Apoptosis Induction in Peripheral Blood Lymphocytes. Xth

International Congress of the Saudi Hematology Society, Madina Monwara 20-

22 December, 2011.

64. Mohamed F.Elshal: Potential Role of CD146 in Lymphocyte Transendothelial

Migration and Inflammation. The Ninth International Conference on Chemistry

and Its Role in Development ICCRD 9th -2007. Sharm Elsheikh, Egypt 16-19

April 2007.

65. Mohamed F.Elshal: Profiling of CD146 (MUC18) Circulating Endothelial Cells”. The

International Conference of Genetic Engineering and Biotechnology, Sharm El-

sheikh, Egypt 16-19 Dec. 2006, Oral Presentation.

66. Mohamed F.Elshal: Profiling of peripheral blood circulating endothelial cells”.

American Heart Association 2005 Annual Scientific Meeting: Dallas

Convention Center -Dallas, TX., USA.

67. Yoshiyuki Takahashi, Abdul Tawab, Roger Kurlander, Mohamed Elshal, Charles

Bolan, E.J. Read, Susan Leitman, J. Philip McCoy, Andreas Lundqvist, Erkut

Bahceci, and Richard Childs. AMD3100 Mobilized Apheresis Products Are

Rich in T-Cells That Do Not Undergo a Th-2 Type Cytokine Polarization:

Implications for Allografting. Blood, Nov 2005; 106: 296.

68. Lundqvist, N. Hamoui, J. Andersson, M. Elshal, Y. Takahashi, R. Srinivasan, D.

Suffredini, P. J. McCoy, Jr., and R. Childs. Allograft Cell Content and GVHD

Differ in Murine Recipients of AMD3100 Versus G-CSF Mobilized Peripheral

Blood Stem Cells. Blood, Nov 2005; 106: 3108.

69. Raghavachari, N; Khan, SS; Elshal, M; et al.Transcript profiling of peripheral blood

circulating endothelial cells. Circulation Volume: 112 Issue: 17 Pages: U275-

U276 Published: OCT 25 2005.

70. Mohamed F. Elshal: Heterogenity of Spermatozoal DNA content in Infertile Men And

Its Relationship to Sperm Motility and Semen Quality”. ESLM’S First Arab

Congress “Advanced Laboratory Technology – The Quest for the Best”; Cairo,

Egypt.


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71. Mohamed F. Elshal: The chromatin structure and in-situ denaturation of nuclear DNA

in sperms of infertile men”. The 5th National Conference of Biochemistry and

Molecular Biology, Cairo, Egypt.

72. Mohamed F. Elshal: Cellular prolifer Helicobacter pylori”. International Health,

Alexandria, Egypt.

73. Mohamed F. Elshal: Correlation between endoscopy, histopathology and DNA flow

cytometry in patients with gastric Dyspepsia". 4th United European

Gastroenterology Week –50th Anuual Meeting of the German Society of

Gastroenterology and Metabolisim - 2th United European Gastroenterology

Meeting Gut: S2(37): 211; 1995, Berlin, Germany.

74. Mohamed F. Elshal: A study of the cellular DNA flow cytometry and the high

molecular weight cytokeratin expression in gastric epithelial cells". 4th United

European Gastroenterology Week –50th Annual Meeting of the German Society

of Gastroenterology and Metabolisim - 2th United European Gastroenterology

Meeting Gut: S2(37): 212; 1995, Berlin, Germany.

(11) THESES

75. M.F. Elshal: Utilization of Flow Cytometry in the Assessment of Genetic

Abnormalities in gastrointestinal disorders. Ph.D. Thesis, Mansoura University,

2001.

76. M.F. Elshal: Quantitative Analysis of Cellular DNA-Content using Flow Cytometry.

(Master Thesis). Mansoura University, 1996.

(12) CONFERENCES and WORKSHOPS

1. The 3rd International Genomic Medicine Conference (The 3rd IGMC, 2015),

Jeddah, KAU. Saudi Arabia.

2. Recent Advances in Flow Cytometry. The first BD Biosciences Research Users'

meeting for the Middle East region on Dec. 11 & 12, 2014 in Dubai.

3. International Genomic Medicine Conference in Saudi Arabia. Jeddah, KSA

November 24-26, 2013.

4. Xth International Congress of the Saudi Hematology Society, Madina Monwara 20-

22 December, 2011.

5. Mesenchymal Stem Cells: Sources and Potential Applications. Workshop on stem

cell will be held in March, 21st, WESTEIN HOTEL, Jeddah, KSA, February 2010.

6. The Ninth International Conference on Chemistry and Its Role in Development

ICCRD 9th -2007. Sharm Elsheikh, Egypt 16-19 April 2007.

7. The International Conference of Genetic Engineering and Biotechnology, Sharm El-

sheikh, Egypt 16-19 Dec. 2006.

8. American Heart Association 2005 Annual Scientific Meeting: Dallas Convention

Center -Dallas, TX., USA.


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9. American Society of Hematology 46th Annual Meeting: San Diego , CA , USA .

published as an abstract in Blood (ASH Annual Meeting Abstracts), Nov 2004.

10. ESLM’S First Arab Congress “Advanced Laboratory Technology – The Quest for

the Best”; Cairo, Egypt, March 2001.

11. The 5th National Conference of Biochemistry and Molecular Biology, Cairo, Egypt,

14-16 May 2002.

12. International conference on infectious diseases and public.health, Alexandria, Egypt,

October 17-20, 1997.

(13) FUNDED PROJECTS

1. Mohamed Farouk Elshal, Jalauldin A. Khan, Khaled Omr Aboulnaja. Comparative

study between Peripheral Vascular Permeability in Diabetic and non-diabetic

hyperinsulinemia models in rats. Project No. 3-23/429 funded by Deanship of

Scientific Research, King Abdulaziz University, KSA.

2. Mohamed Farouk Elshal, Taha Koumosani, Khalid O. Abulnaja, Therapeutic

effects of some natural products extracts on lowering cardiovascular diseases risk

caused by endothelial cells dysfunction in diabetic and obese diabetic rats. Project

No. 185/428 funded by Deanship of Scientific Research, King Abdulaziz University,

KSA.

3. Jalaluldin Aazem Khan, Ahmed N. Abou-Khatwa, Mohamed Farouk Elshal.

Elucidation of the possible causes of camels’ death in some regions of Saudi Arabia

using biochemical, microbiological, toxicological and immunological approaches.

Project No. 165/428 funded by Deanship of Scientific Research, King Abdulaziz

University, KSA.

4. Mohamed Farouk Elshal, Abdulrahman O. Almalki, Comparison of the

biochemical effects of Lepidium sativum and Bisphosphonate on glucocorticoid

induced osteoporosis in adult female rats. Project No.: 3-87/428 funded by Deanship

of Scientific Research, King Abdulaziz University, KSA.

5. Jalaluldin Aazem Khan, Mohamed Abdulsalam, Mohamed Farouk Elshal,

Investigating the cytotoxic effects of carbon nanotubes on human blood

lymphocytes: A flow cytometric study. Project No. 3-107/428 funded by Deanship of

Scientific Research, King Abdulaziz University, KSA.

6. Alia M. A. Aldahlawi, Mohamed F. Elshal. Dendritic cells Generation from

Leukocytes Depleted Fraction, King Abdulaziz University- Deanship of Scientific

research, 2011.

7. Mohamed F. Elshal, Alia M. Dahlawi: Studying modulatory effects of Prostaglandin

E2 on dendritic cells-induced apoptosis by breast cancer. DSR funded project 2013.

8. Mohamed F. Elshal, Taha A. Kumosani, Essam I. Azhar, Alia M. Aldahlawi.

Quantification of circulating endothelial and progenitor cells as biomarkers for

dengue virus infection. DSR project 2013.

9. Saleh Mohamed, Mohamed Elshal: Enzymatic Approaches for Controlling Tumor

growth “Project number: 11-BIO-1516-03”, 2014.


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10. Kaltoom Elsakaf, Mohamed Elshal, et al.,: Studying the abnormalities of the

cellular energy dependant AMP-activated protein kinase signalling pathway in

obesity and the risk of breast cancer development in Saudi Arabia “Project number:

10-BIO1255-03, 2014.

11. Mohamed F. Elshal, Alia M. Aldahlwi, Omar I. Saadah: Assessment of the

expression of CD200 and CD200r on cells from patients with inflammatory bowel

disease and their association with inflammatory markers. (DSR, KAU, KSA)

(RG/32/02), 2015.

(14) THESES SUPERVISION:

1. Rania Mostafa Sultan: Study of the immunological changes associated with some

gastrointestinal diseases using flow cytometry. Chemistry Department, Faculty

of Science, Mansoura University, 2002-2005.

2. Sherif Ghobrial: Effects of DDB , glycyrrhizin, Curcumin and their combinations on

experimentally induced-hepatic injury. Molecular Biology department, Genetic

Engineering and Biotechnology Research Institute. 2004-2007

3. Patul Redini, Response of liver and heart functions to L-Carnitine intake in a model of

nonalcoholic fatty liver disease in rats. Biochemistry Department, Faculty of

Science, King Abdulaziz University, 2008:2010.

4. Khalid Al-Ghamdi: The biochemical effects of some plant extracts on vascular

endothelial dysfunction in type II diabetic rats, Biochemistry Department,

Faculty of Science, King Abdulaziz University, 2009-2011

5. Laila Al-Domiati: Impact of systemic lupus erythemotosus on chemokines expression

& apoptosis induction in perphral blood lymphocyte. Biochemistry Department,


6. Fae Talal: Impact of Rheumatoid Arthritis on chemokines expression & apoptosis

induction in perphral blood lymphocyte. Biochemistry Department, Faculty of

Science, King Abdulaziz University, 2010-2012

7. Abdel-Aziz Al-Oraby: Vitamin D binding protein (DBP) role in the development of

cardiovascular diseases in hemodialysis patients. Biochemistry Department,


8. Mohamed Abdo Asiri: The diagnostic value of B-type natriuretic peptide for detection

of cardiovascular diseases in peroteneial dialysis patients. Biochemistry

Department, Faculty of Science, King Abdulaziz University, 2010-2013

9. Arwa Al-Zeheri: The impact of different biological modifiers on the stimulation of

monocyte derived dendritic cells toward breast cancer cell line. Department of

Biological Sciences, Faculty of Science, King Abdulaziz University, 2011-2014

10. Amany Al-Zahrani: Studying The Capacity of Boswellia sacra Essential Oil in

Directing Dendritic Cells Differentiation, Maturation, and Immunological


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Functions. Department of Biological Sciences, Faculty of Science, King

Abdulaziz University, 2012-2015.

11. Mashael Fahad Al-Otaibi: "Association of Vitamin.D with Cardiometabolic Risk

Factors in Rheumatoid Arthritis & Systemic Lupus Erythematosus Patients"

Biochemistry Department, Faculty of Science, King Abdulaziz University, May

2016.

12. Rawan Abdulwahed: " Modulation of CD28 and p38 expression by treatment with

vitamin D in patients with rheumatoid arthritis". Biochemistry Department,

Faculty of Science, King Abdulaziz University, May 2016.

(15) EDITORIAL BOARD MEAMBERSHIP AND REVIWEING COMMITEES:

1. Editor for Journal of Medical Laboratory and Diagnosis

2. Reviewer for Journal of Human and Experimental Toxicology

3. Reviewer for Clinical Immunology Journal

4. Reviewer for Archives of Medical Sciences

5. Reviewer for Journal of Pediatric Biochemistry

6. Reviewer for Journal of Reproductive Sciences

7. Reviewer for Journal of Human Reproductive Sciences

8. Reviewer for Journal of Systems Biology in Reproductive Medicine

9. Reviewer for Journal of Biomarker Insights

10. Reviewer for Journal of Medical Laboratory and Diagnosis

11. Reviewer for Journal of King Saud University (Science)

12. Reviewer for Journal of King Abdulaziz University (Science)

13. Reviewer for King Abdulaziz City for Sciences and Technology, KSA

14. Reviewer for the Deanship of Scientific Research, Taif University, KSA

(16) RESEARCH EXPERIENCE

A. IN THE FIELD OF FLOW CYTOMETRY

DNA Ploidy status and Cell cycle analysis

Intracellular protein analysis

Cellular proliferation assays

Immunophenotyping

Multiparametric analysis

Rare cells isolation and characterization

Sperm chromatin structure assay “SCSA”

Oncogenes analysis (p53, BAX, Bcl-2, p21)

Functional assays (proliferation, oxidative stress, apoptosis)

Experience running different types of flow cytometers and cell sorter:

BD FACScalibur, BD FACSAria, and FACScanto flow cytometers,


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Bekman-Coulter Cyan flow cytometer

Bekman-Coulter Navious flow cytometer.

Amnis flowsight image cytometer

B. IN THE FIELD OF STEM CELLS

Separation and Maintenance using Magnetic beads separation and Flow

cytometry cell sorter.

Identifying new therapeutics targeting cancer stem cells in vitro using Tissue

culture techniques and flow cytometry

Monitoring response to treatment.

C. IN THE FIELD OF IMMUNOLOGY

Immunophenotyping assays,

Proliferation assays,

magnetic bead separation and sorting assays,

Enzyme Linked Immunosorbent Assay.

MULTIPLEX BEAD-ARRAY ASSAYS (using Luminex bead array

technology)

Hormones analysis,

Cytokines analysis,

Genes analysis,

Soluble proteins analysis.

D. IN-VIVO TECHNIQUES

Tumor induction in experimental animals and methods of treatment thereof.

Induction of Angiogenesis and methods of treatment.

Induction of diabetes type 1 and type 2 in experimental animals and test

antidiabetic drugs.

Induction of hepatic fibrosis in animal models using chemical and test new

materials to treat these abnormalities.

Induction of Cardiac diseases and test compounds that has possible therapeutic

effects.

(17) TEACHING EXPERIENCE:

A. Basic Biochemistry courses

Biochemistry of Metabolism II BIOC 312

Biochemistry of Bioenergetics BIOC 331

Biochemistry of Proteins

Biochemistry of Carbohydrates

Biochemistry of Lipids

Biochemistry of Vitamins

B. Advanced Biochemistry courses (Post graduate)

Medical Biochemistry

Metabolism and its regulation

Biochemistry of oncogenes

C. Immunology courses

Basic Immunology


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Immunological techniques

Biochemistry of the immune system BIOC 446

D. Flow Cytometry course (Post graduate)

Basics in Cytometry

Nucleic Acid Analysis

Immunophenotyping Assays

Functional Assays

Leukemia and Lymphoma

E. Cancer Molecular Biology course (Post graduate)

Basics in cancer Biology

Oncogenes

Molecular Biochemistry

F. Career Skills and Scientific Writing

(18) COMPUTER SKILLS

o Flow cytometry Complex data analysis using FCS-Express V3.0,

o Flow-Jo multi-analysis of flow cytometric data

o Cell cycle analysis using MOD-FIT,

o Immunophenotyping analysis using different flow cytometry softwares.

o Multiplex Bead Array Assay Analysis software on Luminex xMAP Bead Array

Platform.

o Statistical softwares: SPSS, MedCalc, and Instat.

o MS-DOS, Microsoft windows and Office applications: Microsoft office.

(19) MEMBERSHIPS

The Egyptian Society of Biochemistry and Molecular Biology.

The Egyptian Society of Genetics.

International Clinical Cytometry Society

curriculum vitae (1) personal data: dr. mohamed farouk...

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