gnipst bulletin 29.4.pdf

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25th

October , 2013 Volume No.: 29 Issue No.: 0

Contents Message from GNIPS

Letter to the Editor News Update

Health awareness

Disease Outbreak Ne

Forth Coming Events

Drugs Update

Campus News

Students Section

Editors Note

Archive

Vision

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O

PHARMACEUTICAL AND BIOLOGICAL SCIENCE

EDITOR: Soumya BhattacharyaGURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND

TECHNOLOGY

GNIPST Photo Gallery

For your comments/contributionORFor Back-Issues,

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MESSAGE FROM GNIPSTGNIPST BULLETIN is the official publication of Guru Nanak

Institute of Pharmaceutical Science & Technology. All the members

of GNIPST are proud to publish the 29th Volume of GNIPSTBULLETIN. Over the last two years this bulletin updating readers

with different scientific, cultural or sports activities of this

prestigious institute and promoting knowledge of recent development

in Pharmaceutical and Biological Sciences. Students section is

informing readers about some curious facts of drug discovery, science,

sports and other relevant fields. We look forward to seeing your

submission and welcome comments and ideas you may have.

LETTER TO THE EDITOR.

NEWS UPDATE

World Polio Day,2013 (24thOctober, 2013)

World Polio Day was observed globally on 24th

October. World PolioDay aims to shed light on October 24th, which marks the month in

which Jonas Salk was born (28th October). Jonas was the leader of

the team that invented the first polio vaccine in 1955. Polio was once a

disease feared worldwide, striking suddenly and paralysing mainly

children for life. There are several partners in the Global Polio

Eradication Initiative, the largest private-public partnership for

health, which has reduced polio by 99%. Polio now survives onlyamong the world's poorest and most marginalized communities,

where it stalks the most vulnerable children. The Initiative's goal is to

reach every last child with polio vaccine and ensure a polio free world

for future generations.Read more

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Experimental drug reduces brain damage in rodents

afflicted by stroke (25thOctober, 2013)

An experimental drug called 3K3A-APC appears to reduce brain

damage, eliminate brain hemorrhaging and improve motor skills in

older stroke-afflicted mice and stroke-afflicted rats with comorbid

conditions such as hypertension, according to a new study from Keck

Medicine of USC.Read more

Genetic variants associated with bronchodilatorresponsiveness (25thOctober, 2013)

A new study from Brigham and Women's Hospital (BWH) reveals

several new gene variants that are associated with how people living

with chronic obstructive pulmonary disease (COPD) respond to

inhaled bronchodilators. COPD is a progressive breathing disorder

that limits airflow in the lungs. Bronchodilators are medicines used toalleviate respiratory disorder symptoms.Read more

High-Dose Statins Reduce Gum Inflammation in

Heart Disease Patients(3 rd October, 2013)

Statins, commonly prescribed medications for lowering cholesterol,

also reduced inflammation associated with gum disease in a newstudy published in the Journal of the American College of Cardiology. The

study suggests that steps taken to reduce gum disease may also

reduce inflammation in the arteries and vice versa.Read more

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Anti-Cancer drug benefits women with breast

cancer who have failed previous treatments (27thSeptember, 2013)

First results from a phase III clinical trial of the combination drug, T-

DM1, show that it significantly improves the length of time before the

disease worsens in women with advanced HER2 positive breast

cancer whose cancer has recurred or progressed despite previous

treatments, including trastuzumab and lapatinib.Read more

HEALTH AWARENESS

Polio-An overview

Polio is a highly infectious disease caused by a virus. It invades the

nervous system, and can cause total paralysis in a matter of hours. Thevirus enters the body through the mouth and multiplies in the

intestine. Initial symptoms are fever, fatigue, headache, vomiting,

stiffness in the neck and pain in the limbs. One in 200 infections leads

to irreversible paralysis (usually in the legs). Among those paralysed,

5% to 10% die when their breathing muscles become immobilized.

People most at risk

Polio mainly affects children under five years of age.

Prevention

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There is no cure for polio, it can only be prevented. Polio vaccine,

given multiple times, can protect a child for life.

Global caseload

Polio cases have decreased by over 99% since 1988, from an estimated

350 000 cases in more than 125 endemic countries then, to 223

reported cases in 2012. In 2013, only parts of three countries in the

world remain endemic for the diseasethe smallest geographic area in

historyand case numbers of wild poliovirus type 3 are down to

lowest-ever levels.

The Global Polio Eradication Initiative

Launch

In 1988, the forty-first World Health Assembly adopted a resolution

for the worldwide eradication of polio. It marked the launch of the

Global Polio Eradication Initiative (GPEI), spearheaded by national

governments, WHO, Rotary International, the US Centers for Disease

Control and Prevention (CDC), UNICEF, and supported by key

partners including the Bill and Melinda Gates Foundation. This

followed the certification of the eradication of smallpox in 1980,

progress during the 1980s towards elimination of the poliovirus in the

Americas, and Rotary Internationals commitment to raise funds to

protect all children from the disease.

Progress

Overall, since the GPEI was launched, the number of cases has fallen

by over 99%. In 2013, only three countries in the world remain polio-

endemic: Nigeria, Pakistan and Afghanistan.

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In 1994, the WHO Region of the Americas was certified polio-free,

followed by the WHO Western Pacific Region in 2000 and the WHO

European Region in June 2002. Of the three types of wild poliovirus

(type 1, type 2 and type 3), type 2 wild poliovirus transmission has

been successfully stopped (since 1999).

More than 10 million people are today walking, who would otherwise

have been paralysed. An estimated more than 1.5 million childhood

deaths have been prevented, through the systematic administration of

Vitamin A during polio immunization activities.

Opportunity and risks: an emergency approachThe strategies for polio eradication work when they are fully

implemented. This is clearly demonstrated by Indias success in

stopping polio in January 2011, in arguably the most technically-

challenging place. However, failure to implement strategic

approaches leads to ongoing transmission of the virus. Endemic

transmission is continuing in Nigeria, Pakistan and Afghanistan.

Failure to stop polio in these last remaining areas could result in asmany as 200 000 new cases every year, within 10 years, all over the

world.

Recognizing both the epidemiological opportunity and the significant

risks of potential failure, the World Health Assembly in May 2012

adopted a resolution declaring the completion of polio eradication a

programmatic emergency for global public health and called for the

development of a comprehensive polio eradication and endgame

strategy through 2018 to secure a lasting polio-free world.

Subsequently, the three remaining endemic countries launched

national polio emergency action plans, overseen in each case by the

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respective head of state, and the partner agencies of the GPEI also

moved their operations to an emergency footing, working under the

auspices of the Global Emergency Action Plan 2012-2013. By the start

of 2013, the impact of the emergency approaches is being seen, with

the lowest number of reported cases in fewer districts of fewer

countries than at any previous time.

Since then, the new Polio Eradication and Endgame Strategic Plan

2013-2018 has been developed, in consultation with polio-affected

countries, stakeholders, donors, partners and national and

international advisory bodies. The new Plan was presented at a

Global Vaccine Summit in Abu Dhabi, United Arab Emirates, at theend of April 2013. It is the first plan to eradicate all types of polio

disease simultaneously both due to wild poliovirus and due to

vaccine-derived polioviruses. Global leaders and individual

philanthropists signaled their confidence in the Plan by pledging

three-quarters of the Plans projected US$5.5 billion cost over the six

years. They also called upon additional donors to commit upfront the

additional US$1.5 billion needed to secure a lasting polio-free world.Future benefits of polio eradication

Once polio is eradicated, the world can celebrate the delivery of a

major global public good that will benefit all people equally, no

matter where they live. Economic modelling has found that the

eradication of polio would save at least US$ 4050 billion over the

next 20 years, mostly in low-income countries. Most importantly,success will mean that no child will ever again suffer the terrible

effects of lifelong polio-paralysis.

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(Based on WHO factsheet)

DISEASE OUTBREAK NEWS

Human infection with avian influenza A(H7N9) virus(24th October,2013)The National Health and Family Planning Commission, China

notified WHO of a new laboratory confirmed case of human infection

with avian influenza A (H7N9) virus.Read more

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FORTHCOMING EVENTS

The 2nd Pharm. Tech IAPST International Conference on "New insights intodiseases and recent therapeutic approaches" from 17th to 19th January 2014 in

Kolkata, India.Read more

DRUGS UPDATES

FDA approves second brain imaging drug to help

evaluate patients for Alzheimers disease,

dementia (25th October, 2013)

The U.S. Food and Drug Administration today approved Vizamyl

(flutemetamol F 18 injection), a radioactive diagnostic drug for use

with positron emission tomography (PET) imaging of the brain inadults being evaluated for Alzheimer's disease (AD) and dementia.

Read more

CAMPUS NEWS

Students of GNIPST organized pre puja celebration programme,

Saaranya on 7th October, 2013 in college Auditorium.

GNIPST organized a garment distribution programme on 28thSeptember, 2013 at Dakshineswar Kali Temple and Adyapith,

Kolkata. On this remarkable event about hundred people have

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received garments. More than hundred students and most of the

faculties participated on that day with lot of enthusiasm.

GNIPST celebrated World Heart Day (29th September) andPharmacists Day(25th September) on 25thand 26th September,

2013 in GNIPST Auditorium. A seminar on Violence against

woman and female foeticide was held on GNIPST Auditorium on

25th September organized by JABALA Action Research

Organization. On 26th September an intra-college Oral and Poster

presentation competition related to World Pharmacists day and

Heart day was held in GNIPST. Ms. Purbali Chakraborty of

B.Pharm 4th year won the first prize in Oral Presentation. Thewinner of Poster presentation was the group of Ms. Utsa Sinha,

Mr. Koushik Saha and Mr. Niladri Banerjee (B.Pharm 4th year). A

good number of students have participated in both the competition

with their valuable views.

STUDENTS SECTION

WHO CAN ANSWER FIRST????

Name of which disease was derived from Greek

word for grey?

Who first developed oral polio vaccine?Answer of Previous Issues Questions:

A) Rabies B)Louis Pasteur

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Identify the personality

Solve the Puzzle

If x=3, Box=40, then Men=?

Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for StudentsSection& answers of this Section [email protected]

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EDITORS NOTE

I am proud to publish the 4

th

issue of 29

th

Volume of GNIPSTBULLETIN. GNIPST BULLETIN now connected globally through

facebook account GNIPST bulletin

I want to convey my thanks to all the GNIPST members and the

readers for their valuable comments, encouragement and supports.

I am thankful to Dr. Abhijit Sengupta, Director of GNIPST for his

valuable advice and encouragement. Special thanks to Dr. Prerona

Saha andMr. Debabrata Ghosh Dastidar for their kind co-operation

and technical supports. I am thankful to Mr. Subha Bhattacharjee

for his contribution to solve the puzzle section.

An important part of the improvement of the bulletin is the

contribution of the readers. You are invited to send in your write ups,

notes, critiques or any kind of contribution for the forthcoming special

and regular issue.

ARCHIVE

Teachers daywas celebrated on 5th September, 2013 by the

students of GNIPST in GNIPST Auditorium.

Azalea (exotic flower ) , the fresher welcome programme fornewcomers of GNIPST in the session 2013-14 was held on 8thAugust in GNIPST Auditorium.

One day seminar cum teachers development programme forschool teachers on the theme ofRecent Trends of Life Sciences

in Higher Education organized by GNIPST held on 29th June,

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2013 at GNIPST auditorium. The programme was inaugurated by

Prof . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy

Director of JIS Group and Dr. Abhijit Sengupta, Director cum

Principal of GNIPST with lamp lighting. The programme started

with an opening song performed by the B.Pharm students of this

institute. The seminar consists of a series of lectures, video

presentations and poster session. On the pre lunch session 4

lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata

Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty

respectively. On their presentation the speakers enlighten the

recent development of Pharmacy, Genetics and Microbiology and

their correlation with Life Sciences. On the post lunch session, Ms.Saini Setua and Ms. Sanchari Bhattacharjee explained the recent

development and career opportunities in Biotechnology and

Hospital Management. The programme was concluded with

valedictory session and certificate distribution.

About 50 Higher secondary school teachers from different

schools of Kolkata and North& South 24 Parganas district of

West Bengal participated in this programme. A good interactivesession between participants and speakers was observed in the

seminar. The seminar was a great success with the effort of

faculties, staffs and students of our Institute. It was a unique

discussion platform for school teachers and professional of the

emerging and newer branches of Life Science.

The following B.Pharm. final year students have qualified,

GPAT-2013. We congratulate them all.

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The general body meeting of APTI, Bengal Branch has been conducted

at GNIPST on 15th June, 2012. The program started with a nice

presentation by Dr. Pulok Kr. Mukherjee, School of Natural Products,

JU on the skill to write a good manuscript for publication in impact

journals. It was followed by nearly two hour long discussion among

more than thirty participants on different aspects of pharmacy

education. Five nonmember participants applied for membership onthat very day.

GNIPST is now approved by AICTE and affiliated to WBUT for

conducting the two years post graduate course (M.Pharm) in

P H A R M A C O L O G Y . The approved number of seat is 18.The number of seats in B.Pharm. has been increased from 60 to 120.

AICTE has sanctioned a release of grant under Research Promotion

Scheme (RPS) during the financial year 2012-13to GNIPST as per the

details below:

a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical

Science & Technology.

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b.Principal Investigator: Dr. LopamudraDutta.

c. Grant-in-aid sanctioned:Rs. 16,25000/- only

d.Approved duration: 3 years

e. Title of the project: Screening and identification of potentialmedicinal plant ofPurulia & Bankura districts of West Bengal with

respect to diseases such as diabetes, rheumatism, Jaundice,

hypertension and developing biotechnological tools for enhancing

bioactive molecules in these plants.

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