infection and immunityiai.asm.org/content/27/3.toc.pdffatal measles infection in marmosets ......

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INFECTION AND IMMUNITY Volume27 Contents for March 1980 Number3 Bacterial and Mycotic Infections Haemophilus influenzae b Infection in Rats: Effect of Splenectomy on Bloodstream and Meningeal Invasion After Intravenous and Intranasal Inoculations. E. R. MOXON,* J. F. GOLDTHORN, AND A. D. SCHWARTZ ......................................... 872-875 Isolation and Characterization of Arginine Auxotrophs of Cryptococ- cus neoformans. JUDITH C. RHODES* AND DEXTER H. How- ARD .............. ...................... 910-914 Growth Characteristics and Pathogenesis of Experimental Pneumo- cystis carindi Pneumonia. PETER D. WALZER,* RALPH D. Pow- ELL, JR., KOKICHI YONEDA, MARY ELLEN RUTLEDGE, AND JAMES E. MILDER ....................................... 928-937 Production of Bacteremia and Meningitis in Infant Rats with Group B Streptococcal Serotypes. PATRICIA FERRIERI,* BARBARA BURKE, AND JOANN NELSON .......................... 1023-1032 Viral Infections Role of Specific Cytotoxic Lymphocytes in Cellular Immunity Against Murine Cytomegalovirus. MONTO Ho ... ...... 767-776 Failure to Detect Naturally Occurring Serum Inhibitors of Hepatitis B Virus Deoxyribonucleic Acid Polymerase. G. HESS,* W. AR- NOLD, H. H. DORMEYER, W. KOESTERS, G. GAHL, H. G. HOFF- MANN, H. SCHONBORN, AND K. H. MEYER ZUM BUSCHENFELDE 793-797 Diminished Antiviral Effect of Human Interferon in the Presence of Therapeutic Concentrations of Antineoplastic Agents. THOMAS C. CESARIO* AND LEWIS M. SLATER ..... ......... 842-845 Murine Cytomegalovirus: Detection of Latent Infection by Nucleic Acid Hybridization Technique. KWOK-SING CHEUNG,* ENG- SHANG HUANG, AND DAVID J. LANG ................ ...... 851-854 Autoimmunity Induced by Syngeneic Splenocyte Membranes Carry- ing Irreversibly Adsorbed Paramyxovirus. MONROE D. EATON 855-861 Alveolar Macrophage Ingestion and Phagosome-Lysosome Fusion Defect Associated with Virus Pneumonia. GEORGE J. JAKAB,* GLENN A. WARR, AND PHILIP L. SANNES ....... 960-968 Fatal Measles Infection in Marmosets: Pathogenesis and Prophy- laxis. PAUL ALBRECHT,* DOUGLAS LORENZ, MICHAEL J. KLUTCH, JAMES H. VICKERS, AND FRANCIS A. ENNIS ... 969-978 Identification of Lactate Dehydrogenase-Elevating Virus as the Eti- ological Agent of Genetically Restricted, Age-Dependent Po- lioencephalomyelitis of Mice. DOUGLAS MARTINEZ,* MARGO A. BRINTON, THOMAS G. TACHOVSKY, AND ANDRE H. PHELPS 979-987 Rabies Serogroup Viruses in Neuroblastoma Cells: Propagation, "Autointerference," and Apparently Random Back-Mutation of Attenuated Viruses to the Virulent State. H F. CLARK ...... 1012-1022 Oral Microbiology and Immitnology Carbon Dioxide Metabolism by Capnocytophaga ochracea: Identi- fication, Characterization, and Regulation of a Phosphoenol- pyruvate Carboxykinase. PAUL A. KAPKE, ALBERT T. BROWN,* AND THOMAS T. LILLICH .. ............................ .. 756-766 Continued on following page

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INFECTION AND IMMUNITYVolume27 Contents for March 1980 Number3

Bacterial and Mycotic InfectionsHaemophilus influenzae b Infection in Rats: Effect of Splenectomy

on Bloodstream and Meningeal Invasion After Intravenous andIntranasal Inoculations. E. R. MOXON,* J. F. GOLDTHORN, ANDA. D. SCHWARTZ ......................................... 872-875

Isolation and Characterization of Arginine Auxotrophs of Cryptococ-cus neoformans. JUDITH C. RHODES* AND DEXTER H. How-ARD .............. ...................... 910-914

Growth Characteristics and Pathogenesis of Experimental Pneumo-cystis carindi Pneumonia. PETER D. WALZER,* RALPH D. Pow-ELL, JR., KOKICHI YONEDA, MARY ELLEN RUTLEDGE, ANDJAMES E. MILDER ....................................... 928-937

Production of Bacteremia and Meningitis in Infant Rats with GroupB Streptococcal Serotypes. PATRICIA FERRIERI,* BARBARABURKE, AND JOANN NELSON.......................... 1023-1032

Viral InfectionsRole of Specific Cytotoxic Lymphocytes in Cellular Immunity

Against Murine Cytomegalovirus. MONTO Ho ... ...... 767-776Failure to Detect Naturally Occurring Serum Inhibitors of Hepatitis

B Virus Deoxyribonucleic Acid Polymerase. G. HESS,* W. AR-NOLD, H. H. DORMEYER, W. KOESTERS, G. GAHL, H. G. HOFF-MANN, H. SCHONBORN, AND K. H. MEYER ZUM BUSCHENFELDE 793-797

Diminished Antiviral Effect of Human Interferon in the Presence ofTherapeutic Concentrations ofAntineoplastic Agents. THOMASC. CESARIO* AND LEWIS M. SLATER ..... ......... 842-845

Murine Cytomegalovirus: Detection of Latent Infection by NucleicAcid Hybridization Technique. KWOK-SING CHEUNG,* ENG-SHANG HUANG, AND DAVID J. LANG ................ ...... 851-854

Autoimmunity Induced by Syngeneic Splenocyte Membranes Carry-ing Irreversibly Adsorbed Paramyxovirus. MONROE D. EATON 855-861

Alveolar Macrophage Ingestion and Phagosome-Lysosome FusionDefect Associated with Virus Pneumonia. GEORGE J. JAKAB,*GLENN A. WARR, AND PHILIP L. SANNES ....... 960-968

Fatal Measles Infection in Marmosets: Pathogenesis and Prophy-laxis. PAUL ALBRECHT,* DOUGLAS LORENZ, MICHAEL J.KLUTCH, JAMES H. VICKERS, AND FRANCIS A. ENNIS... 969-978

Identification of Lactate Dehydrogenase-Elevating Virus as the Eti-ological Agent of Genetically Restricted, Age-Dependent Po-lioencephalomyelitis of Mice. DOUGLAS MARTINEZ,* MARGOA. BRINTON, THOMAS G. TACHOVSKY, AND ANDRE H. PHELPS 979-987

Rabies Serogroup Viruses in Neuroblastoma Cells: Propagation,"Autointerference," and Apparently Random Back-Mutation ofAttenuated Viruses to the Virulent State. H F. CLARK ...... 1012-1022

Oral Microbiology and ImmitnologyCarbon Dioxide Metabolism by Capnocytophaga ochracea: Identi-

fication, Characterization, and Regulation of a Phosphoenol-pyruvate Carboxykinase. PAUL A. KAPKE, ALBERT T. BROWN,*AND THOMAS T. LILLICH .. ............................ .. 756-766

Continued on followingpage

continued from precedingpage

Virulence of Streptococcus mutans: Restoration of Pathogenesis ofa Glucosyltransferase-Defective Mutant (C4). MASATOMO HIR-ASAWA, HIROSHI KIYONo, TETSUO SHIOTA, RICHARD A. HULL,RoY CURTISS III, SUZANNE M. MICHALEK, AND JERRY R.MCGHEE* ...............................................

Effect of Growth Conditions on Sucrose Phosphotransferase Activityof Streptococcus mutans. A. M. SLEE* AND J. M. TANZER ...

Determination of the Specificity of Plasma Cells for Bacterial Anti-gens In Situ. STEVEN E. SCHONFELD* AND JONATHAN M.KAGAN ......................................

Virulence of Streptococcus mutans: In Vivo Reversion of a Low-Virulence Mutant Results in Partial Displacement and Patho-genesis. MASATOMO HIRASAWA, HIROSHI KIYONO, TETSUOSHIOTA, JAMES L. BABB, SUZANNE M. MICHALEK, AND JERRYR. McGHEE* .......................................

Pathogenic Mechanisms, Ecology, and EpidemiologyIsolation and Characterization of Melanin-Producing (met) Mutants

of Vibrio cholerae. BRUCE E. IVINS AND RANDALL K.HOLMES*.

Opsonization of Four Bacteroides Species: Role of the ClassicalComplement Pathway and Immunoglobulin. ROBERT W.ToFTE,* PHILLIP K. PETERSON, DAVID SCHMELING, JAMESBRACKE, YOUNGKI KIM, AND PAUL G. QUIE .... ..

Attachment of Proteus mirabilis to Human Urinary Tract EpithelialCells In Vitro Is Different from That of Escherichiacoli. CATHARINA SVANBORG EDEN,* PETER LARSSON, ANDHELENA LOMBERG ........................................

In Vitro Studies of Interaction of Rickettsia and Macrophages: Effectof Ultraviolet Light on Coxiella burnetii Inactivation and Mac-rophage Enzymes. JAMES S. LITTLE,* RICHARD A. KISHIMOTO,AND PETER G. CANONICO .......................

Comparison of Virulence Markers of Peritoneal and Fallopian TubeIsolates with Endocervical Neisseria gonorrhoeae Isolates fromWomen with Acute Salpingitis. D. L. DRAPER,* J. F. JAMES,G. F. BROOKS, AND R. L. SWEET* ................

Isolation and Characterization of Spontaneously Arising Auxotrophicand Kanagawa Phenomenon-Negative Mutants of Vibrio para-haemolyticus. DON G. BURSTYN, LORE A. MCNiCOL, AND M.J. VOLL* ........ ... ... ... .... ....

Curing of a Plasmid Is Correlated with an Attenuation of Virulencein the Marine Fish Pathogen Vibrio anguillarum. JORGE H.CROSA,* LINDA L. HODGES, AND MICHAEL H. SCHIEWE ....

Hemagglutination Properties and Adherence Ability of Aeromonashydrophila. H. M. ATKINSON AND T. J. TRUST* ....

Effects of a Single Hit from Alpha Hemolysin Produced by Esche-richia coli on the Morphology of Sheep Erythrocytes. SALLYE. JORGENSEN,* ROBERT F. HAMMER, AND GRACE K. WU ....

Role of Antibody and Complement in Control of EncephalitozoonA cuniculi Infections by Rabbit Macrophages. JERRY Y. NIED-

ERKORN* AND JOHN A. SHADDUCK .... .... ......

ImmunologyGenetic Resistance to Trypanosoma congolense Infections in

Mice. DOUGLAS D. WHITELAW,* JAMES A. MACASKILL, PETERH. HOLMES, FRANCIS W. JENNINGS, AND GEORGE M. URQUHART

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995-1002

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Alteration of Polymorphonuclear Leukocyte Activity by Viable Can-dida albicans. ANTHONY E. HILGER* AND DAVID L. DANLEY

Mechanisms of Immunity in Typhus Infection: Analysis of Immunityto Rickettsia mooseri Infection ofGuinea Pigs. JAMES R. MUR-PHY, CHARLES L. WISSEMAN, JR.,* AND PAUL FISET ......

Biological Activities of Fragments Derived from BordetellapertussisEndotoxin: Isolation of a Nontoxic, Shwartzman-Negative LipidA Possessing High Adjuvant Properties. GERARD AYME, MAR-TINE CAROFF, RICHARD CHABY, NICOLE HAEFFNER-CAVAILLON,ANNICK LE DUR, MONIQUE MOREAU, MIRCtA MUSET, MARIE-CLAUDE MYNARD, MICHA ROUMIANTZEFF, DOMINIQUESCHULTZ, AND LADISLAS SZABO* ...........................

Anti-Inulin [f8-(2--1)-Linked Polyfructose] and Anti-Grass Levan[/3-(2--6)-Linked Polyfructose] Antibody Response in Mice. C.C. CHIEN ...........................................

Influence of Anti-Slime Glycolipoprotein Serum on the InteractionBetween Pseudomonas aeruginosa and Macrophages.PASQUALE F. BARTELL* AND ARTHUR KRIKSZENS ........

Enhanced Phagocytosis and Bactericidal Activity of Hepatic Retic-uloendothelial System During Endotoxin Tolerance. GIUSEPPERUGGIERO, AUGUSTO ANDREANA, RICCARDO UTILI,* AND Do-MENICO GALANTE ...............................

Demonstration of a New Type of Immunoglobulin G Receptor inStreptococcus zooepidemicus Strains. ERLING B. MYHRE* ANDGORAN KRONVALL .........................................

Antibodies Against the Measles Matrix Polypeptide After ClinicalInfection and Vaccination. CAROLYN E. MACHAMER, EDWARDC. HAYES, SUSAN D. GOLLOBIN, LINDA K. WESTFALL, AND HANSJ. ZWEERINK* ...... .... .... ... ..... ...... ...

Immunostimulant Activities of a Lipophilic Muramyl Dipeptide De-rivative and of Desmuramyl Peptidolipid Analogs. MONIQUEA. PARANT, FRAN ,COISE M. AUDIBERT, LOUIS A. CHEDID, *MICHEL R. LEVEL, PIERRE L. LEFRANCIER, JEAN P. CHOAY,AND EDGAR LEDERER .....................................

Hemolytic Complement and Serum C3 Levels in Zebu Cattle Infectedwith Trypanosoma congolense and Trypanosoma vivax and theEffect of Trypanocidal Treatment. F. R. RURANGIRWA, H.TABEL, G. Loss, AND I. R. TIZARD* .......................

Effect of Treponema pallidum-Infected Testis Supernatants on theCellular Response of Normal Rabbit Lymphocytes. KONRADWICHER,* VICTORIA WICHER, AND DOROTHY KAMINSKI ...

Humoral and Cellular Immune Responses Qf Seronegative ChildrenVaccinated with a Cold-Adapted Influenza A/HK/123/77(HlNl) Recombinant Virus. ARYE LAZAR, NOBUHIKO OKABE,AND PETER F. WRIGHT* ...................................

Cell-Mediated Immune Response of Human Lymphocytes to Influ-enza A/USSR (HiN1) Virus Infection. ARYE LAZAR AND PE-TER F. WRIGHT* ........................................

Antibacterial Activity of Bladder Surface Mucin Duplicated in theRabbit Bladder by Exogenous Glycosami'o'glycan (Sodium Pen-tosanpolysulfate). C. LOWELL PARSONS,* JEFFREY J. POLLEN,HABIBULLAH ANWAR, AND JOSEPH D. SCHMIDT ...

Breast Milk Lymphocyte Response to K1 Antigen of Escherichiacoli. MARGARET A. KELLER,* JEWEL L. TURNER, JOAN A.STRATTON, AND MICHAEL E. MILLER ... ...

Continued

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Heterogeneity of Group A Type-Specific Antibodies. A. M. ELKHOLY, K. HAFEZ, N. GUIRGUIS, R. R. FACKLAM,* D. R. JOHN-SON, AND L. WANNAMAKER ................................ 953-959

Measles-Specific Antibodies in Sera and Cerebrospinal Fluids ofPatients with Multiple Sclerosis. EDWARD C. HAYES, SUSAND. GOLLOBIN, CAROLYN E. MACHAMER, LINDA K. WESTFALL,AND HANS J. ZWEERINK* ............. 1033-1037

/; Lack of Immunoglobulin M Suppression by Immunoglobulin G An-tibody in Thymectomized, Irradiated, and Bone Marrow-Recon-stituted Mice Infected with Toxoplasma gondii. JENNY AR-YANPOUR, ABBAS HAFIZI, AND FARROKH MODABBER* ......

* Asterisk refers to person to whom inquiries regarding the paper should be addressed.1038-1040

Volume 27 Contents for January 1980Bacterial and Mycotic Infections

Demonstration of Specific Binding Sites for Human Serum Albuminin Group C and G Streptococci. ERLING B. MYHRE* AND

GORAN KRONVALL. ...................................... 6-14Vaccination of Cows with a K99 Extract to Protect Newborn Calves

Against Experimental Enterotoxic Colibacilliosis. B. NAGY 21-24Concanavalin A-Mediated Affinity Film for Treponema pallidum.

J. B. BASEMAN,* Z. ZACHAR, AND N. S. HAYES .............. 260-263

Viral InfectionsImmunosuppressive Effect of Murine Cytomegalovirus. L. LOH AND

J. B. HUDSON ...................... 54-60

Serum Antibodies to Herpes Simplex Virus Type 1 During ActiveOral Herpes Infection. JOAN J. RATNER* AND KENDALL 0.SMITH .................................. 113-117

Different Susceptibilities of Skin to Type 1 and Type 2 HerpesSimplex Viruses in Newborn Rabbits. JANG 0. OH* ANDPETROS MINASI ....................... ......... 168-174

Dengue-2 Vaccine: Preparation from a Small-Plaque Virus Clone.KENNETH H. ECKELS,* VENTON R. HARRISON, PETER L. SUM-MERS, AND PHILIP K. RUSSELL ............................. 175-180

Dengue-2 Vaccine: Viremia and Immune Responses in Rhesus Mon-keys. ROBERT McN. ScoTr,* ANANDA NISALAK, KENNETH H.EcKELs, MARKPOL TINGPALAPONG, VENTON R. HARRISON,DOUGLAS J. GOULD, FRANK E. CHAPPLE, AND PHILIP K. Rus-

SELL ............... 181-186

Oral Microbiology and ImmunologyVirulence of Streptococcus mutans: Revertants of Mutant C4. T.

IKEDA,* S. OTAKE, M. HIRASAWA, K. WILLIAMS, H. KIYOYONO,J. R. McGHEE, AND T. SHIOTA ............................. 25-31

Effect of Cultural Conditions on Trimethylsilyl-Sugar Profiles ofStreptococcus mutans. D. B. DRUCKER* AND H. S. ALuYi 32-37

Ecological Relationships of Bacteria Involved in a Simple, MixedAnerobic Infection. D. MAYRAND * AND B. C. MCBRIDE.44-50

Requirements for Fatty Acid Synthesis and a Chelation-SensitiveStep in the Production of Glucosyltransferase by Streptococcusmutans. HOWARD K. KURAMITSU* AND LILLIAN WONDRACK 107-112

Neutrophil Chemotaxis Dysfunction in Human Periodontitis. T. E.VAN DYKE, H. U. HOROSZEWICZ, L. J. CIANCIOLA, AND R. J.GENCO* ................................................. 124-132

Purification and Characterization of a Rhamnose-Containing CellWall Antigen of Streptococcus mutans B13 (Serotype d). AK-RAPORN PRAKOBPHOL, ROSEMARY LINZER, * AND ROBERT J.GENCO .................................................. 150-157

Characterization of Tufted Streptococci Isolated from the "CornCob" Configuration of Human Dental Plaque. CHRISTIANMOUTON,* HOMER S. REYNOLDS, AND ROBERT J. GENCO.235-245

Biological and Chemical Characterization of Endotoxin from Cap-nocytophaga sputigena. R. H. STEVENS,* M. N. SELA, W. P.MCARTHUR, A. NOWOTNY, AND B. F. HAMMOND 246-254

Asterisk refers to person to whom inquiries regarding the paper should be addressed.

Number 1

CONTENTS

Detection of a Fibroblast Proliferation Inhibitory Factor from Cap-nocytophaga sputigena. R. H. STEVENS,* M. N. SELA, J. SHAP-IRA, AND B. F. HAMMOND ................................. 271-275

Pathogenic Mechanisms, Ecology, and EpidemiologyProteolytic Action of Legionella pneumophila on Human Serum

Proteins. HANS E. MOLLER .............................. 51-53Binding of Cholesterol by Sulfhydryl-Activated Cytolysins. MARY

K. JOHNSON,* CHRISTIANE GEOFFROY, AND JOSEPH E. ALOUF 97-101Action of Bacterial Lipopolysaccharide on the Respiration of Mouse

Liver Mitochondria. ANNE MCGIVNEY AND S. G. BRADLEY* 102-106Immunochemical Studies of the Lipopolysaccharides of Vibrio chol-

erae: Constitution of O-Specific Side Chain and Core Polysac-charide. SYED RAZIUDDIN ................................ 211-215

Production of K99 Antigen by Enterotoxigenic Escherichia coliStrains of Antigen Groups 08, 09, 020, and 0101 Grown atDifferent Conditions. FRITS K. DE GRAAF,* FRAN B. WIENTJES,AND PIA KLASSEN-BOOR .. ....................... 216-221

Prevalence of Pilus Antigens, Enterotoxin Types, and Enteropatho-genicity Among K88-Negative Enterotoxigenic Escherichia colifrom Neonatal Pigs. H. W. MOON,* E. M. KOHLER, R. A.SCHNEIDER, AND S. C. WHIPP ............................. 222-230

Experimental Syphilis and Serological Examination for Trepone-matosis in Hares. I. HORVATH,* F. KEMENES, L. MOLNAR, A.SZEKY, AND I. RACZ .............................. 231-234

Ganglioside and Monosaccharide Inhibition of Nonspecific Lympho-cyte Mitogenicity by Group A Streptococcal Pyrogenic Exotox-ins. PATRICK M. SCHLIEVERT, DIANE J. SCHOETTLE,AND DEN-NIS W. WATSON* ........................................ 276-279

Transduction of Staphylococcal Enterotoxin B Synthesis: Establish-ment of the Toxin Gene in a Recombination-DeficientMutant. WILLIAM M. SHAFER AND JOHN J. IANDOLO* 280-282

ImmunologyAnalysis of the Anticomplementary Activity in Sera of Three African

Patientswith Parasitic and Bacteriological Infections. MICHAELLOOS* AND MANFRED P. DIERICH .......................... 1-5

Effect of Rifampin on the Immune Response in Mice. AREZKIBELLAHSj:NE AND ARNE FORSGREN* .......... 15-20

Immunization of Mice with Trypanosoma cruzi Polyribosomes. L.L. LEON,* W. LEON, L. CHAVES, S. C. G. COSTA, M. QUEIROZCRUZ, H. M. BRASCHER, AND A. OLIVEIRA LIMA . 38-43

Resistance to Listeriosis in Mice That Are Deficient in the FifthComponent of Complement. JEAN-CLAUDE PETIT .......... 61-67

Host Defenses in Murine Malaria: Immunological Characteristics ofa Protracted State of Immunity to Plasmodium yoelii. JAMESR. MURPHY .............................................. 68-74

Etiology of the Liver Granulomatous Response in Schistosoma mar-soni-Infected Athymic Nude Mice. ADELE F. AMSDEN, Dov L.BOROS,* AND ANDREW T. HOOD ....................... 75-80

Influence of Route of Administration on Immediate and ExtendedProtection in Rats Immuunized with Escherichia coli Heat-La-bile Enterotoxin. FREDERICK A. KLIPSTEIN* AND RICHARD F.ENGERT .. ........... ... ....... .... .... 81-86

CONTENTS

Effect of Selenium and Dimethyl Dioctadecyl Ammonium Bromideon the Vaccine-Induced Immunity of Swiss-Webster MiceAgainst Malaria (Plasmodium berghei). ROBERT S. DESO-WITZ * AND JOHN W. BARNWELL ........................... 87-89

Depression of B-Lymphocyte Levels in the Peripheral Blood of Cowswith Mastitis. THOMAS J. YANG,* PATRICIA A. JANTZEN-ABO,AND LEANDER F. WILLIAMS .................. . 90-93

Absorption of Ablastic Activity from Mouse Serum Using a Trypa-nosma musculi Population Rich in Dividing Forms. BRADFORD0. BROOKS AND NORMAN D. REED* ........................ 94-96

Enzyme-Linked Immunosorbent Assay for Group B StreptococcalAntibodies. NEAL S. ROTE,* NANCY L. TAYLOR, ANN 0. SHI-GEOKA, JAMES R. SCOTT, AND HARRY R. HILL ..... 118-123

Cell-Mediated Immunity Against Herpes Simplex Induction of Cy-totoxic T Lymphocytes. MICHAEL J. P. LAWMAN, BARRY T.RouSE,* RICHARD J. COURTNEY, AND ROBERT D. WALKER ... 133-139

Experimental Murine Candidiasis: Cell-Mediated Immunity AfterCutaneous Challenge. STEPHEN A. MOSER,* JUDITH E.DOMER, AND FRANCES J. MATHER ............ 140-149

Effect of Prostaglandins and Cyclic Adenosine 3',5-MonophosphateModulators on Herpes Simplex Virus Growth and InterferonResponse in Human Cells. KENNETH F. TROFATTER, JR.,* ANDCHARLES A. DANIELS ..................................... 158-167

Transfer Factor: a Murine Model. MICHAEL E. WILLIAMS ANDCAROL A. KAUFFMAN* .. . ............. .... ...... 187-191

Effect of T-Cell Deficiency on the Chronicity of Arthritis Induced inMice by Mycoplasma pulmonis. EDWARD C. KEYSTONE, *DAVID TAYLOR-ROBINSON, MARY F. OSBORN, LUCY LING,CHRISTINE POPE, AND VICTOR FORNASIER ........ 192-196

Immunogenicity of the Ribosomal Fraction of Salmonella typhimu-rium: Analysis of Humoral Immunity. EIJI KITA* AND SHUZOKASHIBA ........... 197-203

Ribonuclease-Sensitive Ribosomal Vaccine of Pseudomonas ae-ruginosa. RINSKE GONGGRIJP,* WIL J. H. A. MULLERS, PAULJ. M. R. LEMMENS, AND C. P. A. VAN BOVEN ............ 204-210

Immunofluorescent Characterization of Lymphocytes in Lungs ofRats Infected with Mycoplasma pulmonis. JERRY K. DAVIS,PHILLIP A. MADDOX, RANDY B. THORP, AND GAIL H. CASSELL* 255-259

Rate of Clearance of Virulent Treponema pallidum (Nichols) fromthe Blood Stream of Normal, Mycobacterium bovis BCG-Treated, and Syphilitic Rabbits. STEPHEN GRAVES .... 264-267

Difference in Antigen-Presenting Ability of Macrophages BetweenHigh- and Low-Responder Mice in Delayed-Type Hypersensi-tivity to Mycobacterium bovis BCG. REIKO M. NAKAMURA,*TOHRU TOKUNAGA, AND SABURO YAMAMOTO .......... ..... 268-270

Volume 27 Contents for February 1980 Number 2

Bacterial and Mycotic InfectionsIsolation of Deoxyribonucleic Acid from Mycobacterium avium

by Rapid Nitrogen Decompression. PAUL M. YANDELL ANDCHAROLOrTE MCCARTHY* ................................. 368-375

CONTENTS

Growth Characteristics ofGroup A Streptococci in a New ChemicallyDefined Medium. I. VAN DE RIJN* AND R. E. IKESSLER ..... 444-448

Genetic Mapping in Phage Group 2 Staphylococcus aureus. ScoTrM. MARTIN, STEVEN C. SHOHAM, MARGARET ALSUP, AND MAR-VIN ROGOLSKY* .......................................... 532-541

Adherence of Candida albicans to a Fibrin-Platelet Matrix FormedIn Vitro. PATRICIA A. MAISCH AND RICHARD A. CALDERONE* 650-656

Viral InfectionsRestriction Endonucleases in Identification of a Genome Type

of Adenovirus 19 Associated with Keratoconjunctivitis.GCRAN WADELL* AND J. C. DE JONG ...... ................. 292-296

Replication of Rubella Virus in Human Mononuclear BloodCells. J. T. M. VAN DER LOGT, A. M. VAN LOON, AND J. VANDER VEEN*.*... ............................... 309-314

Shift in the Prevalent Human Rotavirus Detected by RibonucleicAcid Segment Differences. ROMILIo T. ESPEJo,* ONOFRE MU-&6z, FRANCISCO SERAFIN, AND PEDRO ROMERO .......... ... 351-354

Significance of Bursa of Fabricius as Target Organ in InfectiousBursal Disease of Chickens. ILSE KAUFER AND EUGEN WEISS* 364-367

Pathology of Chickens Infected with Avian .Nephroblastoma VirusMAV-2(N). SUSAN L. WATTS AND RALPH E. SMITH* ........ 501-512

Antiviral Cell-Mediated Immune Responses and Effect of Chromo-some Polymorphism in Herpesvirus saimiri-Infected Monkeys.RUSSELL H. NEUBAUER,* HARVEY RABIN, AND FRANCES E.DUNN . ................................................. 549-555

Oral Microbiology and ImmunologySialidase-Enhanced Lectin-Like Mechanism for Actinomyces visco-

sus and Actinomyces naeslundii Hemagglutination. R. P. EL-LEN,* E. D. FILLERY, K. H. CHAN, AND D. A. GROVE .......... 335-343

Excretion of Extracellular Lipids by Streptococcus mutans BHT andFA-1. ERLINDA CABACUNGAN AND RONALD A. PIERINGER* 556-562

Evidence for an Immunological Relationship Between Streptococcusmutans and Human Cardiac Tissue. MICHAEL HUGHES,* SU-SAN M. MACHARDY, ANTHONY J. SHEPPARD, AND NICHOLAS C.WOODS .................................................. 576-588

Immunochemical Differences Between Oral and Nonoral Strains ofBacteroides asaccharolyticus. BERNARD J. MANSHEIM* ANDSYLVIA E. COLEMAN ........... ........................... 589-596

Binding of Streptococcal Antigens to Muscle Tissue In Vitro.MURRAY W. STINSON,* RUSSELL J. NISENGARD, AND EARL J.BERGEY ................................................. 604-613

Streptococcus mutans Adherence: Presumptive Evidence for Pro-tein-Mediated Attachment Followed by Glucan-Dependent Cel-lular Accumulation. ROBERT H. STAAT,* SHARON D. LANGLEY,AND R. J. DOYLE ......................................... 675-681

Adherence of Oral Streptococci to Keratinized and NonkeratinizedHuman Oral Epithelial Cells. ALEXANDRA SKLAVOUNOU ANDGREG R. GERMAINE* ........... .......................... 686-689

Virulence of Streptococcus mutans: Immunochemical Characteriza-tion of a Serotype g-Defective Mutant (C307). MASATOMOHIRASAWA, HIROSHI KIYONo, TETSUO SHIOTA, SUZANNE M.MICHALEK, AND JERRY R. MCGHEE* ...... ................. 697-699

CONTENTS

Pathogenic Mechanisms, Ecology, and EpidemiologyIron Acquisition by Neisseria meningitidis In Vitro. FRED S. AR-

CHIBALD AND I. W. DEVOE* ...............................

Cecal Toxin(s) from Guinea Pigs with Clindamycin-Associated Co-litis, Neutralized by Clostridium sordellii Antitoxin. JEROLDE. REHG ........................

Mucin Model for Group B Type III Streptococcal Infection inMice. DIANE 0. FLEMING ................................

Bacterial Translocation from the Gastrointestinal Tract of Athymic(nu/nu) Mice. WILLIAM E. OWENS AND RODNEY D. BERG* ..

Properties of Selected Rickettsiae of the Spotted Fever Group.ROBERT L. ANACKER,* THOMAS F. MCCAUL, WILLY BURGDOR-FER, AND ROBERT K. GERLOFF .............................

High-Molecular-Weight Antigenic Protein Complex in the OuterMembrane of Neisseria gonorrhoeae. WILBERT J. NEW-HALL V, CHARLES E. WILDE III, WILLIAM D. SAWYER, ANDRICHARD A. HAAK* .......................................

Inhibition of Ribonucleic Acid Synthesis by Group A StreptococcalPyrogenic Exotoxin. PATRICK M. SCHLIEVERT, KRISTINE M.BETTIN, AND DENNIS W. WATSON* .........................

Adherence ofPseudomonas aeruginosa to Tracheal Cells Injured byInfluenza Infection or by Endotracheal Intubation. REUBENRAMPHAL, PETER M. SMALL, JOSEPH W. SHANDS, JR., WERNERFISCHLESCHWEIGER, AND PARKER A. SMALL, JR.* ...........

Sexual Transmission of Spotted Fever Group Rickettsiae by InfectedMale Ticks: Detection of Rickettsiae in Immature Spermatozoaof Ixodes ricinus. STANLEY F. HAYES,* WILLY BURGDORFER,AND ANDRE AESCHLIMANN ................................

Comparison of Escherichia coli Fimbrial Antigen F7 with Type 1Fimbriae. IDA 0RSKOV,* FRITS 0RSKOV, AND AKSEL BIRCH-ANDERSEN ...............................

Adherence of Candida albicans and Other Candida Species toMucosal Epithelial Cells. ROBERT D. KING,* JEAN C. LEE,AND ANTOINETTE L. MORRIS ...........................

Plasmid Associated with Pathogenicity and Calcium Dependency ofYersinia enterocolitica. P. GEMSKI,* JANET R. LAZERE, ANDT. CASEY ................................................

Influence of Serum Concentration on Opsonization by the Classicaland Alternative Complement Pathways. ROBERT W. TOFrE,,*PHILLIP K. PETERSON, YOUNGKi KIM, AND PAUL G. QUIE ..

Chemotaxigenesis by Encapsulated Staphylococcus aureus M.DAVID J. SCHMELING,* PHILLIP K. PETERSON, IRWIN M. BARR,YOUNGKI KiM, AND PAUL G. QUIE ........... ..............

Immunology

Enzyme-Linked Immunosorbent Assay for Antibodies to Toxplasmagondii Polysaccharides in Human Toxoplasmosis. JOSE R. MI-NEO, MARIO E. CAMARGO,* AND ANTONIO W. FERREIRA ......

Failure of Synthetic Muramnl Dipeptide to Increase AntibacterialResistance. H. FINGER AND C.-H. WIRSING VON KoNIG ....

In Vitro Synthesis of Anti-Mycobacterial Antibodies in Biopsies fromSkin Lesions of Leprosy Patients. RUDY F. M. LAI A FAT,JIMMY CHAN PIN JIN, RALPH VAN FURTH, AND MORTEN HAR-BOE ....................................................

322-334

387-390

449-454

461-467

468-474

475-482

542-548 F

614-619

638-642

657-666

667-674

682-685

693-696

700-703

283-287

288-291

297-301

CONTENTS

Bacteriostatic Effect of Serum: Role of Antibody to Lipopolysaccha-ride. S. PETER FITZGERALD AND HENRY J. ROGERS* ........ 302-308

Immunological Characterization of Two Major Proteins Isolatedfrom the Outer Membrane of Proteus mirabilis. FELIZITASBUB, PETRA BIEKER, HANS H. MARTIN, AND KATHRYNNIXDORFF* .............................................. 315-321

Isolation, Characterization, and Biological Properties of a Tubercu-lin-Active Peptidoglycan Isolated from the Culture Filtrate ofMycobacterium tuberculosis. K. C. GUPTA* AND S. LANDI . 344-350

Complement-Dependent Antiviral Monospecific Antibody-MediatedLysis of Murine Cells Coated with Sendai Virus or Its EnvelopeComponent. YASUHIRO HOSAKA,* YASUO FUKAMI, YUKO YA-SUDA, AND Josh A. BONILLA ............................... 355-363

Effects of Cyclophosphamide on Murine Candidiasis. STEPHEN A.MOSER* AND JUDITH E. DOMER ........................... 376-386

Biphasic Protection Against Bacterial Infection in Mice Induced byVaccination of Propionbacterium acnes. Funo, KOBAYASHI,*TAKAO NAGOYA, TOMOYUKI KOSHI, AND YUSHI SAINO ....... 391-396

Serology and Energetics of Cross-Reactions Among the H3 Antigensof Influenza Viruses. P. ANNE UNDERWOOD. ............... . 397-404

Comparison of Two Enzyme-Linked Immunosorbent Assays for An-tigen Quantitation: Direct Competition and Antibody Inhibi-tion. J. PETER RISSING,* THOMAS B. BUXTON, ROY A. TAL-LEDO, AND TERRY JOE SPRINKLE ........................ 405-410

Immunoglobulin G and M Antibodies to Pneumococcal Polysaccha-rides Detected by Enzyme-Linked Immunosorbent Assay.DOUGLAS J. BARRETT,* ARTHUR J. AMMANN, SUZANNE STEN-MARK, AND DIANE W. WARA ............................... 411-417

Bacteriostatic Enterochelin-Specific Immunoglobulin from NormalHuman Serum. DAVID G. MOORE, ROBERT J. YANCEY,CHARLES E. LANKFORD, AND CHARLES F. EARHART* .... ..... 418-423

Immunogenicity of Ribosomes from Enzymatically Lysed Strepto-coccus pyogenes. BRUCE A. GREEN AND WILLIAM JOHNSON* 424-430

Isolation of Specific and Common Antibodies to StaphylococcalEnterotoxins B, C1, and C2. AMY C.-M. LEE, RUTH N. ROBBINS,RAOUL F. REISER, AND MERLIN S. BERGDOLL* . ............. 431-434

Correlation of the Duration and Magnitude of Protection AgainstSalmonella Infection Afforded by Various Vaccines with Anti-body Titers. CARL R. ANGERMAN AND TOBY K. EISENSTEIN* 435.443

Thioglycolate Medium Decreases Resistance to Bacterial Infectionin Mice. LAWRENCE A. BAKER AND PRISCILLA A. CAMPBELL* 455-460

In Vitro Stimulation of Human Peripheral Blood Lymphocytes bySoluble and Membrane Fractions ofRenografin-Purified TyphusGroup Rickettsiae. A. LOUIS BOURGEOIS,* GREGORY A.DASCH, AND DOUGLAS M. STRONG ........................ 483-491

Microtiter Enzyme-Linked Immunosorbent Assay for Immunoglob-ulin G Cholera Antitoxin in Humans: Method and Correlationwith Rabbit Skin Vascular Permeability Factor Technique.CHARLES R. YOUNG, MYRON M. LEVINE,* JOHN P. CRAIG, ANDRoY ROBINs-BROWNE...................................... 492-496

Microtiter Enzyme-Linked Immunosorbent Assay for Immunoglob-ulin G Cholera Antitoxin in Humans: Sensitivity and Specific-ity. ROY M. ROBINS-BROWNE, CHARLES R. YOUNG, MYRONM. LEVINE,* AND JOHN P. CRAIG ...... ...... 497-500

CONTENTS

Effect of Dietary Essential Amino Acid Limitations upon NativeLevels of Murine Serum Immunoglobulins, Transferrin, andComplement. THOMAS M. PETRO AND J. K. BHATTACHARJEE* 513-518

Comparative Stimulation of Granulocyte Adherence and Chemotaxisby Bacterial Products. PHILIP J. SPAGNUOLO* AND JERROLDJ. ELLNER ............................................... 519-524

Enzyme-Linked Immunosorbent Assay for Quantitating the HumoralImmune Response to the Colonization Factor Antigen of Enter-otoxigenic Escherichia coli. STEVEN CLEGG,* DOLORES G. Ev-ANS, AND DOYLE J. EVANS, JR............................. 525-531

Immunoglobulin E Antibodies Against Staphylococcus aureus CellWalls in the Sera of Patients with Hyperimmunoglobulinemia Eand Recurrent Staphylococcal Infection. KURT SCHOPFER,*STEVEN D. DOUGLAS, AND BRIAN J. WILKINSON ........... 563-568

New Method for Isolation of Immunologically Pure Pili from Esch-erichia coli. TIMO K. KORHONEN,* EEVA-LnSA NURMIAHO,HELENA RANTA, AND CATHARINA SVANBORG EDPN .......... 569-575

Characterization ofa Flagellar Sheath Protein of Vibrio cholaere. K.W. HRANITZKY, A. MULHOLLAND, A. D. LARSON,* E. R. Eu-BANKS, AND L. T. HART ................................... 597-603-1

Investigation of the Component of Propionibacterium acnes (Cory-nebacterium parvum) Responsible for Macrophage Activation.GEORGE E. BUCK* AND MICHAEL T. KELLY ................. 620-627

Effect of Immunosuppression on the Development of ExperimentalHematogenous Candida Endophthalmitis. DAVID K. HEN-DERSON, LISA J. HOCKEY, LISA J. VUKALCIC, AND JOHN E.EDWARDS, JR.* ........................................... 628-631

Antitoxic Immunity to Cholera in Dogs Immunized Orally withCholera Toxin. NATHANIEL F. PIERCE,* WILLIAM C. CRAY,JR., AND PAMELA F. ENGEL ................................. 632-637

Effects of Activated Macrophages on Nocardia asteroides.GREGORY A. FILICE, BLAINE L. BEAMAN, AND JACK S. REMING-TON * .... ... ... .... ... ... .... ... ... ... 643-649

New Type of Antibody-Enzyme Conjugate Which Specifically KillsCandida albicans. KENJI OKUDA,* KAZUYUKI ISHIWARA,YOSHIKUNI NOGUCHI, TOYOZOH TAKAHASHI, AND ICHIRO TA-DOKORO ............................ ......... 690-692

ErrataFractionation and Properties of Glucans Produced by Streptococcus

mutans. MASAKAZU INOUE AND ToSHIHIKo KOGA ........ .. 704Immunoglobulin Al Protease Production by Haemophilus influ-

enzae and Streptococcus pneumoniae. CAROLYN J. MALE ... 704Host Defenses in Experimental Scrub Typhus: Role of Normal and

Activated Macrophages. CAROL A. NACY AND JOSEPH V. OS-TERMAN ..... ..... .... .... ..... ..... ..... 705

CONTENTS

Volume 27 Contents for March 1980Bacterial and Mycotic Infections

Haemophilus influenza b Infection in Rats: Effect of Splenectomyon Bloodstream and Meningeal Invasion After Intravenous andIntranasal Inoculations. E. R. MoxoN,* J. F. GOLDTHORN, ANDA. D. SCHWARTZ ..... ................ .....

Isolation and Characterization of Arginine Auxotrophs of Cryptococ-cus neoformans. JUDITH C. RHODES* AND DEXTER H. How-ARD.

Growth Characteristics and Pathogenesis of Experimental Pneumo-cystis carinii Pneumonia. PETER D. WALZER,* RALPH D. Pow-ELL, JR., KOKICHI YONEDA, MARY ELLEN RUTLEDGE, ANDJAMES E. MILDER.

Production of Bacteremia and Meningitis in Infant Rats with GroupB Streptococcal Serotypes. PATRICIA FERRIERI,* BARBARABURKE, AND JOANN NELSON ................... ..

Viral InfectionsRole of Specific Cytotoxic Lymphocytes in Cellular Immunity

Against Murine Cytomegalovirus. MONTO Ho ..Failure to Detect Naturally Occurring Serum Inhibitors of Hepatitis

B Virus Deoxyribonucleic Acid Polymerase. G. HESS,* W. AR-NOLD, H. H. DORMEYER, W. KOESTERS, G. GAHL, H. G. HOFF-MANN, H. SCHONBORN, AND K. H. MEYER ZUM BUSCHENFELDE

Diminished Antiviral Effect of Human Interferon in the Presence ofTherapeutic Concentrations ofAntineoplastic Agents. THOMASC. CESARIO* AND LEWIS M. SLATER ... .............

Murine Cytomegalovirus: Detection of Latent Infection by. NucleicAcid Hybridization Technique. KWOK-SING CHEUNG,* ENG-SHANG HUANG, AND DAVID J. LANG ............ ....

Autoimmunity Induced by Syngeneic Splenocyte Membranes Carry-ing Irreversibly Adsorbed Paramyxovirus. MONROE D. EATON

Alveolar Macrophage Ingestion and Phagosome-Lysosome FusionDefect Associated with Virus Pneumonia. GEORGE J. JAKAB,*GLENN A. WARR, AND PHILIP L. SANNES ....... ....

Fatal Measles Infection in Marmosets: Pathogenesis and Prophy-laxis. PAUL ALBRECHT,* DOUGLAS LORENZ, MICHAEL J.KLUTCH, JAMES H. VICKERS, AND FRANCIS A. ENNIS.

Identification of Lactate Dehydrogenase-Elevating Virus as the Eti-ological Agent of Genetically Restricted, Age-Dependent Po-lioencephalomyelitis of Mice. DOUGLAS MARTINEZ,* MARGOA. BRINTON, THOMAS G. TACHOVSKY, AND ANDRE H. PHELPS

Rabies Serogroup Viruses in Neuroblastoma Cells: Propagation,"Autointerference," and Apparently Random Back-Mutation ofAttenuated Viruses to the Virulent State. H F. CLARK ..

Oral Microbiology and ImmunologyCarbon Dioxide Metabolism by Capnocytophaga ochracea: Identi-

fication, Characterization, and Regulation of a Phosphoenol-pyruvate Carboxykinase. PAUL A. KAPKE, ALBERT T. BROWN,*AND THOMAS T. LILLICH ......

Number 3

872-875

910-914

928-937

1023-1032

767-776

793-797

842-845

851-854

855-861

960-968

969-978

979-987

1012-1022

756-766

CONTENTS

Alteration of Polymorphonuclear Leukocyte Activity by Viable Can-dida albicans. ANTHONY E. HILGER* AND DAVID L. DANLEY 714-720

Mechanisms of Immunity in Typhus Infection: Analysis of Immunityto Rickettsia mooseri Infection of Guinea Pigs. JAMES R. MUR-PHY, CHARLES L. WISSEMAN, JR.,* AND PAUL FISET ... 730-738

Biological Activities of Fragments Derived from BordetellapertussisEndotoxin: Isolation of a Nontoxic, Shwartzman-Negative LipidA Possessing High Adjuvant Properties. GERARD AYME, MAR-TINE CAROFF, RICHARD CHABY, NICOLE HAEFFNER-CAVAILLON,ANNICK LE DUR, MONIQUE MOREAU, MIRCEA MUSET, MARIE-CLAUDE MYNARD, MICHA ROUMIANTZEFF, DOMINIQUESCHULTZ, AND LADISLAS SZABO* ....... .................... 739-745

Anti-Inulin [f-(2-41)-Linked Polyfructose] and Anti-Grass LevanIfi-(2-.6)-Linked Polyfructose] Antibody Response in Mice. C.C. CHIEN ..... ...... ........................... 746-755

Influence of Anti-Slime Glycolipoprotein Serum on the InteractionBetween Pseudomonas aeruginosa and Macrophages.PASQUALE F. BARTELL* AND ARTHUR KRIKSZENS .... .... 777-783

Enhanced Phagocytosis and Bactericidal Activity of Hepatic Retic-uloendothelial System During Endotoxin Tolerance. GIUSEPPERUGGIERO, AUGUSTO ANDREANA, RICCARDO UTILI,* AND Do-MENICO GALANTE ........... ................ 798-803

Demonstration of a New Type of Immunoglobulin G Receptor inStreptococcus zooepidemicus Strains. ERLING B. MYHRE* ANDGORAN KRONVALL ...................... ...... 808-816

Antibodies Against the Measles Matrix Polypeptide After ClinicalInfection and Vaccination. CAROLYN E. MACHAMER, EDWARDC. HAYES, SUSAN D. GOLLOBIN, LINDA K. WESTFALL, AND HANSJ. ZWEERINK* ........... 817-825

Immunostimulant Activities of a Lipophilic Muramyl Dipeptide De-rivative and of Desmuramyl Peptidolipid Analogs. MONIQUEA. PARANT, FRANCOISE M. AUDIBERT, LOUIS A. CHEDID,*MICHEL R. LEVEL, PIERRE L. LEFRANCIER, JEAN P. CHOAY,AND EDGAR LEDERER ... 826-831

Hemolytic Complement and Serum C3 Levels in Zebu Cattle Infectedwith Trypanosoma congolense and Trypanosoma vivax and theEffect of Trypanocidal Treatment. F. R. RURANGIRWA, H.TABEL, G. Loss, AND I. R. TIZARD* .... ...... ... 832-836

Effect of Treponema pallidum-Infected Testis Supernatants on theCellular Response of Normal Rabbit Lymphocytes. KONRADWICHER,* VICTORIA WICHER, AND DOROTHY KAMINSKI .. 846-850

Humoral and Cellular Immune Responses of Seronegative ChildrenVaccinated with a Cold-Adapted Influenza A/HK/123/77(HlNi) Recombinant Virus. ARYE LAZAR, NOBUHIKO OKABE,AND PETER F. WRIGHT* ... ....... .... ....... 862-866

Cell-Mediated Immune Response of Human Lymphocytes to Influ-enza A/USSR (HlNi) Virus Infection. ARYE LAZAR AND PE-TER F. WRIGHT* .... ....................... 867-871

Antibacterial Activity of Bladder Surface Mucin Duplicated in theRabbit Bladder by Exogenous Glycosaminoglycan (Sodium Pen-tosanpolysulfate). C. LOWELL -PARSONS,* JEFFREY J. POLLEN,HABIBULLAH ANWAR, AND JOSEPH D. SCHMIDT............. 876-881

Breast Milk Lymphocyte Response to K1 Antigen of Escherichiacoli. MARGARET A. KELLER,* JEWEL L. TURNER, JOAN A.STRATTON, AND MICHAEL E. MILLER ..... .......... 903-909

CONTENTS

Virulence of Streptococcus mutans: Restoration of Pathogenesis ofa Glucosyltransferase-Defective Mutant (C4). MASATOMO HIR-ASAWA, HIROSHI KIYONo, TETSUO SHIOTA, RICHARD A. HULL,RoY CURTISS III, SUZANNE M. MICHALEK, AND JERRY R.MCGHEE*.

Effect of Growth Conditions on Sucrose Phosphotransferase Activityof Streptococcus mutans. A. M. SLEE* AND J. M. TANZER ...

Determination of the Specificity of Plasma Cells for Bacterial Anti-gens In Situ. STEVEN E. SCHONFELD* AND JONATHAN M.KAGAN.

Virulence of Streptococcus mutans: In Vivo Reversion of a Low-Virulence Mutant Results in Partial Displacement and Patho-genesis. MASATOMO HIRASAWA, HIROSHI KIYONo, TETSUOSHIOTA, JAMES L. BABB, SUZANNE M. MICHALEK, AND JERRYR. McGHEE*. .......................

Pathogenic Mechanisms, Ecology, and EpidemiologyIsolation and Characterization of Melanin-Producing (mel) Mutants

of Vibrio cholerae. BRUCE E. IVINS AND RANDALL K.HOLMES*.

Opsonization of Four Bacteroides Species: Role of the ClassicalComplement Pathway and Immunoglobulin. ROBERT W.TOFTE,* PHILLIP K. PETERSON, DAVID SCHMELING, JAMESBRACKE, YOUNGKI KIM, AND PAUL G. QUIE.

Attachment of Proteus mirabilis to Human Urinary Tract EpithelialCells In Vitro Is Different from That of Escherichiacoli. CATHARINA SVANBORG EDEN,* PETER LARSSON, ANDHELENA LOMBERG ............. ...

In Vitro Studies of Interaction of Rickettsia and Macrophages: Effectof Ultraviolet Light on Coxiella burnetii Inactivation and Mac-rophage Enzymes. JAMES S. LITTLE,* RICHARD A. KISHIMOTO,AND PETER G. CANONICO ....... ............

Comparison of Virulence Markers of Peritoneal and Fallopian TubeIsolates with Endocervical Neisseria gonorrhoeae Isolates fromWomen with Acute Salpingitis. D. L. DRAPER,* J. F. JAMES,G. F. BROOKS, AND R. L. SWEET* ............ ....

Isolation and Characterization of Spontaneously Arising Auxotrophicand Kanagawa Phenomenon-Negative Mutants of Vibrio para-haemolyticus. DON G. BURSTYN, LORE A. McNICOL, AND M.J.VOLL* ... ...... .... ..... .... ....

Curing of a Plasmid Is Correlated with an Attenuation of Virulencein the Marine Fish Pathogen Vibrio anguillarum. JORGE H.CROSA,* LINDA L. HODGES, AND MICHAEL H. SCHIEWE.

Hemagglutination Properties and Adherence Ability of Aeromonashydrophila. H. M. ATKINSON AND T. J. TRUST* ... ....

Effects of a Single Hit from Alpha Hemolysin Produced by Esche-richia coli on the Morphology of Sheep Erythrocytes. SALLYE. JORGENSEN,* ROBERT F. HAMMER, AND GRACE K. Wu ....

Role of Antibody and Complement in Control of Encephalitozooncuniculi Infections by Rabbit Macrophages. JERRY Y. NIED-ERKORN* AND JOHN A. SHADDUCK .........

ImmunologyGenetic Resistance to Trypanosoma congolense Infections in

Mice. DOUGLAS D. WHITELAW,* JAMES A. MACASKILL, PETERH. HOLMES, FRANCIS W. JENNINGS, AND GEORGE M. URQUHART

915-921

922-927

947-952

1003-1011

721-729

784-792

804-807

837-841

882-888

889-896

897-902

938-946

988-994

995-1002

707-713

CONTENTS

Heterogeneity of Group A Type-Specific Antibodies. A. M. ELKHOLY, K. HAFEZ, N. GUIRGUIS, R. R. FACKLAM,* D. R. JOHN-SON, AND L. WANNAMAKER..............................

Measles-Specific Antibodies in Sera and Cerebrospinal Fluids ofPatients with Multiple Sclerosis. EDWARD C. HAYES, SUSAND. GOLLOBIN, CAROLYN E. MACHAMER, LINDA K. WESTFALL,AND HANS J. ZWEERINK .... ....... ...

Lack of Immunoglobulin M Suppression by Immunoglobulin G An-tibody in Thymectomized, Irradiated, and Bone Marrow-Recon-stituted Mice Infected with Toxoplasma gondii. JENNY AR-YANPOUR, ABBAS HAFIZI, AND FARROKH MODABBER* .....

953-959

1033-1037

1038-1040