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  • 7/25/2019 Asperger 7

    1/12

    Anxiety in

    Adolescents

    With

    Asperger

    Syndrome:

    Negative

    Thoughts,

    Behavioral Problems,

    and Life Interference

    Sylvana

    Farrugia and

    Jennifer Hudson

    This study

    examined

    anxiety symptoms

    in

    29

    adolescents with

    Asperger

    syndrome (AS)

    aged 12 to 16 years, compared

    to 30

    nonclinical

    (NC)

    adolescents

    and 34 adolescents

    with anxiety

    disorders

    (AD). Comorbidity

    between anxiety

    symptoms

    and

    negative

    thoughts, behavioral problems, and life

    interference

    was also examined. Self- and

    parental reports revealed

    significantly higher

    levels of anxiety in both the AS

    group

    and the AD group

    than in the NC group. Negative

    thoughts,

    behavioral

    problems, and life interference

    were significantly

    higher for the

    AS

    group than

    for

    the two

    comparison

    groups.

    sperger syndrome

    (AS) is

    one

    of

    the five

    pervasive de-

    velopmental

    disorders PDDs) that

    share a cluster of

    developmental

    problems in reciprocal

    social interac-

    tion,

    communication,

    and stereotyped

    interests

    and

    behaviors

    American

    Psychiatric

    Association

    [APA],

    2000).

    S

    is,

    how-

    ever,

    a distinctive subtype

    of PDD, characterized

    by social

    dysfunction

    and idiosyncratic

    interests,

    without clinically sig-

    nificant delay in language

    and

    cognitive development. Diag-

    nosing individuals

    with AS is complicated.

    First, there

    is

    no

    universal agreement

    on diagnostic criteria

    (Klin, Volkmar,

    Sparrow,

    2000).

    Second,

    the

    term

    Aspe ger

    syndrome

    is often

    used synonymously

    with high-functioning

    autism HFA),

    characterizing those who

    function at the

    high

    end of the autis-

    tic

    spectrum disorders ASD),

    a term used synonymously

    with

    PDD Ghaziuddin, 2002).Third,

    individuals

    with

    S

    present

    with high rates

    of comorbid disorders,

    which might delay or

    obscure

    the diagnosis of AS Sverd, 2003).

    Common

    comorbid

    problems in the AS population in -

    dude

    emotional disorders such as anxiety

    and

    depression

    Ghaziuddin,

    Weidmer,

    Ghaziuddin, 1998; Wing, 1981) as

    well as behavioral disorders

    such as conduct disorder

    CD),

    oppositional defiant

    disorder ODD),

    and attention-deficit/

    hyperactivity

    disorder ADHD)

    Barnhill et al.,

    2000;

    Gill-

    berg,

    2002).

    Anxiety and depressive disorders

    are conceptual-

    ized as internalizing

    disorder, while behavior disorders a

    considered externalizing disorders

    (Achenbach, 1985). D

    spite this evidence,

    most

    of the studies

    on comorbidity in

    A

    have focused

    mainly on depression, rather than

    anxiety and b

    havioral

    problems, which

    are the focus

    of

    the present study

    Comorbid

    Anxiety Disorders

    in

    Adolescents With

    AS

    In the PDD population,

    fears are

    very

    common and

    occ

    more

    frequently

    than

    in

    nondisabled controls (Matson

    Lov

    1990).

    Clinically significant

    anxiety, which differs from fe

    on

    level ofseverity, associated

    distress, and life

    interference, h

    also

    been documented. For

    example,

    Gillott,

    Furniss,

    and

    W

    ter (2001)

    found that children

    with HFA

    reported

    signi

    candy higher

    anxiety

    levels

    than

    typically developing

    childre

    however, when

    compared

    to

    the

    clinically anxious

    populatio

    mean,

    children with

    HFA obtained

    lower

    anxiety scores. O

    the

    other hand, two studies using structured

    clinical intervie

    found

    that

    individuals with

    PDD met

    full

    criteria

    for at lea

    one anxiety

    disorder

    (Muris

    Steerneman,

    1998;

    Rumse

    Rapoport, Sceery, 1985).

    Clinicians

    have also observed high

    levels of anxiety

    in

    t

    adolescent

    population

    (Attwood,

    1998;

    Szatmari,

    1991; Ta

    tam, 2000; Wing,

    1996). Despite

    these clinical accounts,

    well as the strong evidence

    that

    anxiety

    disorders are one

    the most common forms

    ofadolescent psychopathology

    (Don

    van

    Spence, 2000), research

    on

    anxiety in

    adolescents wi

    AS

    is still lacking.

    However, the few

    studies that

    have

    emerge

    in recent

    years

    found

    that both

    self- and parental reports

    sho

    that

    adolescents

    with AS have

    significantly

    higher

    levels

    anxiety than

    adolescents in the general

    population (Bellin

    2004;

    Kim, Szatmari,

    Bryson, Streiner,

    Wilson, 200

    Tonge, Brereton,

    Gray, Einfeld,

    1999) and adolescents w,

    CD

    (Green,

    Gilchrist,

    Burton,

    Cox, 2000).

    In

    addition

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    FOCUS ON

    UTISM

    ND OTHER DEVELOPMENT L

    DISABILITIES

    26

    these

    high internalizing

    symptoms,

    adolescents

    with AS

    have

    high levels of

    externalizing

    problems

    (Kim

    et al., 2000).

    In

    fact,

    levels of

    conduct

    and

    overactivity

    symptoms

    are so high

    that adolescents

    with

    AS

    are sometimes

    misdiagnosed

    as

    hav-

    ing

    CD

    (Green

    et al.,

    2000)

    or ADHD

    (Attwood,

    1998).

    Comorbid

    Behavior

    Disorders

    in

    Adolescents

    With S

    In a

    study

    by Green

    and

    colleagues

    2000), adolescents

    with

    AS

    and

    their parents

    reported levels

    of CD,

    ODD,

    and/or

    ADHD

    as

    high as

    adolescents

    with

    CD,

    who like

    adolescents

    with

    AS,

    show a

    failure

    of

    social adaptation,

    even

    though ofa

    different

    etiology. Kim

    and

    colleagues

    2000)

    also

    found

    clin-

    ically

    relevant scores

    ofPADHD

    and

    ODD

    in 9-

    to 14-year-old

    adolescents

    with AS;

    however,

    based on

    parental reports,

    these

    adolescents

    did

    not

    reach clinically

    significantly

    levels

    of CD .

    Tonge

    and colleagues

    (1999)

    found

    that the

    level of

    behav-

    ioral

    problems in

    adolescents

    with

    AS was higher

    than that

    found in

    general

    childhood populations

    (Rutter,

    1989) and

    even

    higher

    than

    that found

    in populations

    with

    intellectual

    disabilities

    (Einfeld

    Tonge,

    1996).

    The

    point

    illustrated

    by these

    studies is

    that

    adolescents

    with AS

    present

    with both

    emotional

    and behavioral

    problems.

    But

    what

    are the risk

    factors

    for these

    comorbid

    problems

    in

    adolescents?

    Apart

    from

    the

    complex

    interplay

    between

    bio-

    logical,

    psychological,

    and

    environmental factors

    (Cooper,

    2000),

    cognition

    has a

    major

    role

    in

    the

    development

    and

    maintenance of

    internalizing

    and

    externalizing

    problems

    in

    clinical

    and community

    samples

    of

    adolescents (Schniering

    Rapee,

    2002,

    2004a,

    2004b).

    Cognitive

    Factors

    in Adolescents

    With S

    According to

    IFrith

    (1991),

    deficits

    in cognitive

    processes

    also

    have

    a

    role in

    the

    multiple behavioral

    manifestations

    exhibited

    by

    adolescents

    with AS.

    Individuals

    with AS have

    difficulties

    in

    conceptualizing

    and

    appreciating the thoughts

    and feelings

    of other

    people Ozonoff

    Miller,

    1995).

    They

    are

    also rigid

    in their thinking (Church,

    Alisanski,

    &Amanullah,

    2000),

    which

    makes

    them

    unable to

    learn

    from mistakes

    (Prior

    Hoff-

    mann, 1990),

    to cope

    with

    being wrong

    (Attwood,

    1998),

    and

    to

    change

    their behavior to

    meet

    environmental

    demands

    (Szatmari,

    Bremner,

    Nagy,

    1989).

    However,

    to our

    knowledge, there

    is no

    research investi-

    gating

    cognitive

    biases

    that

    may

    predispose or

    maintain anxi-

    ety

    and behavioral

    problems

    in adolescents

    with AS.

    On

    the

    other hand,

    cognitive

    factors

    related to depression

    have

    been

    investigated

    by

    two studies

    using the same

    sample

    of thirty-

    three 12-

    to

    18-year-olds

    with AS

    (Barnhill, 2001;

    Barnhill

    Myles,

    2001).

    Barnhill found

    a

    significant

    positive

    relationship

    between depressive

    symptoms

    and

    ability

    attributions

    for

    so-

    cial failure.

    Barnhill

    and Myles

    found

    that adolescents

    with AS

    have

    a learned

    helplessness

    style, meaning

    that

    the

    more de-

    pressive

    symptoms

    reported by the

    adolescents, the

    more

    the

    adolescents

    explained

    negative

    events

    by internal,

    stable, and

    global

    causes.

    These

    results

    are

    consistent with

    studies involv-

    ing clinical

    and

    nonclinical adolescents

    without AS,

    whose de-

    pressive

    symptoms

    were strongly

    predicted by

    thoughts

    on

    personal failure

    (Schniering

    Rapee,

    2002, 2004a,

    2004b).

    These

    researchers

    also

    found

    that anxiety

    symptoms

    were

    strongly

    predicted

    by thoughts

    on social

    threat,

    whereas

    ex-

    ternalizing

    symptoms

    were strongly

    predicted by

    thoughts

    on

    hostility. Thus,

    research

    needs to be

    conducted

    to see if

    the

    cognitions of

    adolescents

    with AS are

    also

    related

    to

    specific

    internalizing

    and

    externalizing

    problems, which

    in the

    general

    population have

    been found

    to

    be

    highly

    distressing,

    leading

    to significant

    life

    interference

    (Schniering

    Rapee, 2002).

    Level

    of

    Distress and

    Life

    Interference

    in

    Adolescents

    With

    S

    Adolescents

    with

    AS experience difficulties

    arising

    from

    their

    core

    symptoms

    (Steyn Le

    Couteur,

    2003). In

    addition, they

    have

    to deal

    with the

    transitional

    changes

    of adolescence,

    which is a

    difficult

    time

    for many teenagers,

    but more so

    for

    adolescents

    with

    AS,

    who

    have

    major

    problems

    with

    peer

    group identification

    and peer relationships

    (Green

    et al.,

    2000).

    In fact,

    Tantam

    (1991) asserted

    that

    AS may cause

    the

    great-

    est disability

    in adolescence, when

    social

    relationships

    are

    the

    key

    to

    almost every achievement. Even

    though

    at times ado-

    lescents

    with AS do not

    consider

    themselves

    to

    be at risk for

    any of

    these

    problems (Barnhill

    et

    al., 2000),

    these

    complexi-

    ties

    dearly

    provide difficulties

    for

    them

    (Groden,

    Cantela,

    Prince,

    Berryman, 1994),

    affecting

    their

    overall

    life

    adapta-

    tion

    and leading to

    a

    highly disabling

    condition

    (Tantam,

    2000).

    Thus

    it

    is important

    that adolescents

    with AS are

    iden-

    tified

    as

    early

    as possible

    and

    provided with

    appropriate

    inter-

    ventions.

    The

    Present

    Study

    Recent

    years have

    witnessed

    numerous

    studies

    on anxiety

    and

    behavior

    disorders in

    adolescents,

    but

    the

    presence

    of

    these

    problems in adolescents

    with

    AS has rarely

    been

    studied. In

    the

    few

    studies that have

    been

    conducted,

    individuals

    with AS

    demonstrated

    high

    levels of

    both anxiety

    and behavioral

    prob-

    lems.

    However,

    none of

    these

    studies

    examined

    anxiety

    and

    behavioral

    problems specifically

    in adolescents

    with AS and

    used

    comparison

    groups to

    tease

    apart

    the

    specificity

    or

    gen-

    erality of

    these

    problems.

    It

    is

    important

    to

    examine anxiety

    and behavioral symp-

    toms

    in adolescents

    with AS

    because

    they

    might represent

    ad-

    I

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    VOLUME 21, NUMBER

    1 SPRING 6

    ditional

    debilitating problems,

    which

    if left untreated might

    lead

    to significant life interference

    and

    persist

    through adult-

    hood. In addition, the potential comorbidity

    of

    these

    two

    problems

    might increase

    the

    overall severity

    of the

    condition.

    This comorbidity of

    emotional and

    behavioral problems,

    as

    well as

    their impact on quality of

    life,

    are

    two other areas

    that

    have

    not

    been

    covered

    in

    the

    studies

    of

    adolescents

    with

    AS.

    In this population

    there is also a paucity of research on cogni-

    tion,

    which in

    the general population has

    been found to be

    a

    critical

    factor

    in the development

    and maintenance

    ofboth

    in-

    ternalizing and

    externalizing disorders.

    The

    reviewed

    studies

    on adolescents

    with AS

    were

    further limited because

    they

    (a) used

    only

    one-tailed

    statistical analysis,

    thus

    predicting

    the

    direction

    of

    the results,

    and

    (b) used either

    a parent or

    self-

    report,

    between which

    there is a demonstrated low

    level of

    agreement

    (Engel, Rodrigue,

    Geften, 1994) that could

    skew

    the results.

    In an effort to address

    these issues,

    the present

    study

    ex-

    amined anxiety symptoms in adolescents

    with

    AS

    and

    provided

    two

    comparison

    groups,

    a

    group

    of

    individuals

    with

    anxiety

    disorders

    (AD) and

    a group of individuals from

    the

    general

    population

    (nonclinical;

    NC). The

    relationship

    betveen

    anxi-

    ety

    symptoms and negative

    automatic thoughts, behavioral

    problems, and life

    interference was also examined.

    The meth-

    odology

    of

    this study was

    strengthened

    by

    the

    use of

    nondi-

    rectional

    two-tailed

    analyses and information

    obtained from

    both adolescents and

    parents.

    The

    purpose of

    the

    present

    study was to

    answer the

    following

    questions:

    1.

    Are adolescents

    diagnosed

    wvith

    AS

    more

    likely

    to

    experience symptoms of

    anxiety

    than

    adolescents in

    the general population?

    And is the level

    of

    anxiety

    experienced

    by adolescents

    with AS as high as that

    experienced

    by adolescents

    with

    AD? It

    was anticipated

    that

    adolescents

    with AS and adolescents

    wvith AD

    would

    both

    manifest

    significantly

    higher

    levels

    of

    anxiety

    than

    the

    NC group.

    2.

    Do the three diagnostic groups

    differ significantly on

    levels

    of

    negative

    automatic thoughts, behavioral prob-

    lems, and life interference?

    Is there a

    correlation between

    any

    of these three

    factors and anxiety

    symptoms? And

    are the negative automatic

    thoughts correlated

    with

    the

    anxiety and

    behavioral

    problems

    exhibited

    by adolescents

    with AS?

    It

    was

    expected

    that

    due to the equivalent

    levels

    of

    anxiety

    symptoms exhibited by adolescents

    wiith AS and

    adolescents

    with

    AD,

    both

    would

    exhibit

    more negative

    thoughts, behav-

    ioral

    problems,

    and life

    interference when compared to

    the NC

    group. It was also

    anticipated that

    threat-based

    thoughts

    would

    correlate

    with

    anxiety

    symptoms, whereas

    hostility cog-

    nitions would

    correlate wvith behavioral problems

    in all

    three

    diagnostic groups.

    2

    Method

    rticip nts

    The sample consisted of 93 adolescents and one of

    their par

    ents:

    29 adolescents with

    AS, 34

    adolescents

    with

    AD, and

    3

    NC

    adolescents.

    The 64

    (69 )

    boys

    and 29

    (31 )

    girls

    wer

    between 12 and

    16 years

    of age,

    with

    a

    mean age of 13.8

    years

    The AD and

    NC groups had similar

    proportions

    of boys

    and

    girls,

    but

    the AS group

    had a higher

    boy

    to girl ratio, which

    consistent

    with the

    gender ratio found in the AS

    population

    (AD:

    19

    boys,

    15

    girls;

    NC:

    19

    boys,

    11 girls; AS: 26 boys

    3 girls).

    Asperger Group. Adolescents with

    AS

    were

    recruited v

    two sources:

    20 from local

    support groups and

    the remain

    ing 80 via the Autism

    Association of

    New South Wale

    (NSW).

    All of the

    adolescents

    in this

    group

    had

    been diag

    nosed

    with AS by qualified

    mental health

    professionals:

    31

    by psychiatrists,

    28

    by

    clinical psychologists,

    21 by child pe

    diatricians

    and

    clinical

    psychologists, 17

    by child pediatri

    cians, and

    one adolescent diagnosed by

    a

    clinical

    psychologis

    and

    a

    psychiatrist.

    These adolescents were

    diagnosed

    within

    the last

    8

    years in

    the following settings: private

    practice (55 )

    the Autism Association of

    NSW (24 ); Forestville

    Autism Aus

    tralia

    (10 ); and the

    Child

    and

    Family Health Center,

    Delphi

    Anxiety,

    and Westmead

    Children's Hospital, with

    the

    latte

    three settings

    diagnosing one adolescent

    each.

    Anxious

    Group.

    Adolescents from

    the

    AD

    sample

    pre

    sented

    for assessment and

    treatment

    at

    the Macquarie

    Un

    versity

    Child and

    Adolescent Anxiety

    Clinic,

    Sydney, A ustralia

    Postgraduate students in

    clinical

    psychology,

    under the super

    vision of experienced

    clinical psychologists,

    interviewed th

    adolescents

    and their

    parents

    separately,

    using

    the Anxiety Dis

    orders

    Interview

    Schedule for DSM IV Child and Parent

    Ver

    sion

    ADIS-IV-C/P;

    Silverman

    Albano, 1996). From th

    assessed 88 participants,

    54 met criteria

    for another disorde

    in

    addition

    to anxiety.

    The present

    study

    included the 34

    ado

    lescents who

    only

    met criteria for anxiety disorders,

    with d

    agnosis based

    on

    interviews

    with both

    parents

    and adolescents

    The

    principal diagnosis

    in

    the

    AD

    group

    included

    the

    follow

    ing:

    generalized

    anxiety

    disorder

    (41 ),

    separation

    anxiety dis

    order

    (18 ),

    social

    phobia

    (18 ),

    obsessive

    compulsive

    disorde

    (15 ), specific

    phobia

    (6 ) and panic

    (3 ),

    with

    73

    diag

    nosed with

    more than one anxiety disorder.

    Nonclinical Group.

    The NC group

    consisted

    of

    adoles

    cents

    recruited

    from

    the

    community

    via an advertisemen

    placed in

    a local

    newspaper.

    To avoid bias,

    the advertisemen

    provided

    a general statement

    that the study was investigatin

    factors affecting

    adolescents.

    The inclusion criterion

    was tha

    these

    adolescents

    have never sought

    treatment from a

    menta

    health

    professional.

    These participants

    were

    not

    interviewed

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    FOCUS ON AUTISM

    AND

    OTHER

    DEVELOPMENTAL DISABILITIES

    28

    because

    we

    did

    not

    want

    to select a

    diagnosis-free

    group.

    Rather,

    we

    wanted

    to make

    comparisons with a more

    normally

    distributed

    nonclinical group.

    It

    is recognized,

    therefore, that

    some of these

    adolescents

    may have

    met

    criteria

    for some

    forms

    of

    psychopathology.

    Since

    the NC group was the

    most

    difficult to recruit,

    these participants received monetary

    com-

    pensation.

    e sures

    Questionnaires. The Children sAutomaticThoughts

    Scale

    (CATS; Schniering

    Rapee, 2002) is a self-report

    of negative

    automatic thoughts

    in children

    aged

    7-16

    years. It consists

    of

    40 items yielding a total score

    and

    four cognitive

    subscales:

    (a)

    Physical Threat, (b) Social Threat,

    (c) Personal Failure, and

    (d)

    Hostile Intent. The

    scale

    effectively

    discriminates between

    nonclinical and clinical

    anxious,

    depressed, or

    behavior disor-

    dered

    children,

    with a

    mean total score

    for the

    community

    group

    significantly lower

    than

    the

    mean for

    the

    anxious

    group

    (mean difference

    = -25.88), the depressed group

    (mean dif-

    ference =

    -30.52), and

    the

    behavior disordered group

    (mean

    difference =

    -11.85). Internal consistency was also

    very high

    (.95), and

    test-retest correlation

    coefficient

    for the total score

    was

    .76 at

    3

    months (Schniering

    Rapee, 2004a, 2004b).

    The present study slightly

    modified the CATS

    self-report

    and

    used

    it

    as

    an informant report

    for the

    AS

    group,

    in

    addition

    to

    self-report.

    The Spence Children sAnxiety

    Scale

    (SCAS;

    Spence, 1998)

    is a

    measure

    of overall

    levels

    of anxiety

    in children

    and adoles-

    cents.

    In

    addition

    to the total score,

    it

    includes six

    subscales

    based

    on

    DSM-IV

    criteria:

    (a)

    Panic/Agoraphobia,

    (b)

    So-

    cial Phobia, (c)

    Separation Anxiety, (d) Generalized

    Anxiety,

    (e) Obsessive-Compulsiveness,

    and (f) Fears

    of Physical

    Injury,

    with the latter

    closely

    resembling Specific

    Phobias in

    DSM-IV.

    The SCAS has

    been found to

    have

    sound

    psychometric prop-

    erties, with

    a

    convergent validity of .75

    and

    an

    internal relia-

    bility

    coefficient

    of

    .93

    and

    a

    Guttman

    split-half

    reliability

    of

    .92 (Spence, Barrett, Turner,

    2003).

    The present study used

    both the SCAS

    self-report and parent report,

    which correlate

    well

    with each other, with parent-child agreement

    ranging

    from

    .41 to

    .66

    (Nauta et al.,

    2004).

    The

    Strengthsand DifficultiesQuestionnaire

    SDQ; Good-

    man, 1997)

    is

    a

    brief

    behavioral screening measure consisting

    of

    25 positive

    and negative attributes that generates scores for

    five

    subscales: (a) Emotional

    Symptoms, (b) Conduct

    Prob-

    lems, (c) Hyperactivity/Inattention,

    (d) Peer Relationship

    Prob-

    lems,

    and (e)

    Prosocial

    Behavior. The first

    four

    subscales

    are

    added to

    provide a

    valid

    total difficulty

    score

    with

    an

    internal

    reliability of.82

    (Goodman, 2001). The SDQ reliability

    is sat-

    isfactory, whether judged

    by

    internal

    consistency

    (mean = .73),

    cross-informant correlation (mean = .34), or retest stability

    up

    to

    6

    months

    (mean = .62) (Goodman, 2001). In the

    present

    study, adolescents

    completed

    the

    self-report

    version

    suitable

    for ages

    11 to 16,

    and

    parents

    completed the informant-rated

    version, which covers

    the

    same

    25 items, thus

    increasing com

    parability

    of

    scores obtained

    from children and parents (Good

    man, Meltzer, Bailey, 2003).

    The

    Life

    nterference

    Measure

    (LIM;

    Lyneham, Abbott,

    Rapee,

    2003) is

    a new self-report questionnaire

    consisting

    of

    31

    items scored

    on a scale

    from

    0 to 4,

    which

    when added to

    gether

    give a

    global

    life

    interference score.

    The

    self-report ver

    sion was slightly

    modified and used as an informant report

    for

    the

    AS group. This measure

    has not

    yet

    been

    analyzed

    for

    psy

    chometric properties; however, an analysis using

    the data

    from

    the present

    study showed high

    internal

    reliability

    for

    both

    the adolescents' (alpha = .95)

    and parents'

    (alpha = .91)

    tota

    score.

    Additional Questions. In

    addition to completing

    the

    four questionnaires (SCAS, SDQ, CATS,

    LIM),

    the parents

    o

    adolescents

    with AS were

    asked

    to

    answer

    the

    following six ad

    ditional

    questions

    written

    by

    the

    researchers: (a)

    In

    which

    clinic/center

    was

    your

    child diagnosed?

    (b)

    Which

    of

    these

    professionals (child

    pediatrician, clinical psychologist, psychia-

    trist,

    other)

    diagnosed

    your

    child? (c) How long ago was

    you

    child diagnosed?

    (d)

    Has

    your

    child ever been given psycho

    logical

    treatment? If

    yes, what

    type of

    treatment?

    (e)

    Has

    you

    child ever

    been

    given

    treatment for

    anxiety symptoms?

    If yes

    what type of

    treatment?

    (f)

    Is your child

    taking

    any

    medica

    tion?

    If

    yes, what type of

    medication and for what problem?

    Procedure

    This

    research

    was

    approved

    by

    Macquarie

    University Ethic

    Review

    Committee, the

    Macquarie University Anxiety Re-

    search

    Unit,

    and

    the

    Education and Research Committee

    o

    the Autism Association

    of

    NSW.

    In the

    AD group,

    parents

    seeking treatment

    for their

    chil

    dren's anxiety contacted

    the

    Child and Adolescent

    Anxiet

    Clinic

    for

    an initial

    assessment. The clinic sent the

    family the

    information/consent form to be signed by

    parents and

    ado

    lescents,

    as well as

    the four parent

    questionnaires

    (SCAS

    CATS, SDQ,

    LIM) and

    the

    two self-questionnaires (SCAS

    SDQ). Participants

    returned the

    questionnaires and consen

    form at

    the time

    of the assessment;

    postgraduate clinical psy

    chology students

    interviewed the parents and adolescents sep

    arately,

    using the

    ADIS-IV-C/P.

    In

    the AS group,

    an

    information

    sheet

    explaining the

    na

    ture

    of

    the

    present study

    was sent

    to five AS support

    groups

    The

    parents

    of interested

    participants were asked to

    contac

    the

    researchers by

    phone. The self-report and parent report o

    the

    four questionnaires

    (SCAS,

    CATS,

    SDQ,

    LIM) were sen

    to

    these participants, together with the six

    additional question

    and

    the information/consent

    form.

    Parents and

    adolescent

    were

    asked to

    separately fill

    in

    the

    questionnaires, which would

    take approximately a

    half

    hour,

    and

    return them

    in

    the self

    addressed envelope.

    Recruitment of other adolescents with AS

    was

    completed through

    the Autism Association of

    NSW. On

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    21, NUMBER

    1,

    SPRING 2006

    2

    hundred

    self-addressed

    envelopes, each

    containing the pack-

    age

    of questionnaires,

    additional questions, and information/

    consent forms, were given

    to

    the principals of four

    different

    schools,

    situated at Central

    Coast, South

    East

    Sydney,

    West-

    ern Sydney,

    and North

    Sydney,

    who

    sent the

    envelopes

    to the

    families of students

    with

    AS;

    participation

    was

    voluntary.

    To

    attend

    these

    particular

    schools,

    the

    adolescents

    had

    to

    have

    been diagnosed

    with

    AS by qualified

    mental

    health profes-

    sionals.

    To validate the self-report

    method of this

    study,

    rather than

    relying

    only

    on

    the answers

    provided by adolescents

    Nith AS,

    who

    might

    have

    misunderstood the items due

    to

    their

    diffi-

    culties with abstract terms,

    a parent version of each

    measure

    was

    included,

    thus

    increasing

    our

    confidence

    that the

    results

    obtained are reliable.

    In the NC group, those interested were

    asked to contact

    the researchers by

    phone.

    After

    ensuring

    that they

    had

    never

    sought

    treatment from mental

    health professionals,

    the re-

    searchers sent

    them a

    self-addressed

    envelope containing

    the

    SCAS

    and

    SDQ parent version

    and

    the

    SCAS, CATS,

    SDQ,

    and LIM self version,

    together with the

    information/consent

    form. Participants

    indicated their willingness

    to participate

    in

    the study by returning

    the signed consent

    form,

    together with

    the

    completed questionnaires,

    to the researchers. These

    par-

    ticipants

    then

    received

    monetary comp ensation for their

    par-

    ticipation.

    Results

    Preliminary

    Analyses

    Gender.

    Although the

    three

    diagnostic

    groups

    differed

    significantly

    with

    respect

    to gender,

    c

    2

    (2, N =

    93)

    = 8.94,

    p

    < .05, no significant

    difference was found

    between

    male and

    female

    scores on the administered measures,

    so gender

    was not

    used as a covariate in

    later

    analyses.

    Age.

    The

    adolescents'

    age was not significantly

    different

    across the three

    diagnostic

    groups,

    F(2, 90) =

    .78,

    p

    >

    .05

    (AS

    group, M = 13.76,

    SD = 1.27;

    AD

    group, M =

    13.82,

    SD

    1.29; NC group,

    M=

    13.90, SD 1.56). In

    addition,

    no

    sig-

    nificant

    correlation

    was

    found

    between

    age

    and

    anxiety

    levels

    as

    measured

    by the

    SCAS self-report

    total score: AS group,

    r(29) = .27, p >

    .05;

    AD

    group, r(34) = .07, p > .05, and NC

    group, ;(30)

    = .35, p > .05.

    Analyses

    Differences

    betveen the three

    diagnostic

    groups

    were investi-

    gated using one-way

    analysis

    of variance

    (ANOVA).

    The

    de-

    pendent

    measures

    for the analyses included

    the raw total scores

    and subscales of

    the SCAS, CATS,

    SDQ,

    and

    LIM,

    both

    par-

    ent and self-report.

    A

    Bonferroni correction was used

    to

    adjust

    for

    inflation

    of

    the Type

    1

    error

    rate

    on

    follow-up comparisons.

    TABLE 1

    Correlation

    Between Adolescent Self-Reports and

    Parent

    Reports in Each Group on All Four Measures

    Asperger Anxious

    Nonclinica

    Measure (n = 29)

    n

    = 34)

    (n = 30)

    SCAS

    .697 *

    .527**

    .433*

    CATS .727**

    SDQ .515** .566**

    .410*

    L M

    .688**

    Note.

    SCAS

    = Spence

    Children s

    Anxiety Scale

    (Spence, 1998 ; CATS =

    Children s

    Automatic Thoughts Scale (Schniering

    Rapee, 2002); SDQ

    Strengths

    and Difficulties

    QuestionnaireGoodman,

    1997 ; LIM = Life

    Interference Measure

    (Lyneham,

    Abbott, Rapee,

    2003 . Dashes indicate

    that

    the

    CATS

    and

    LIM

    measures

    were not

    administered

    to parents

    of

    adolescents in the

    anxiety

    disorders and nonclinical

    groups.

    p