gnipst bulletin 26.3

7/28/2019 Gnipst Bulletin 26.3

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28th

June, 2013 Volume No.: 26 Issue No.: 03

ContentsMessage from GNIPS

Letter to the EditorNews Update

Health awareness

Disease Outbreak Ne

Forth Coming Events

Drugs Update

Campus News

Students Section

Editors Note

Archive

Vision

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O

PHARMACEUTICAL AND BIOLOGICAL SCIENCE

EDITOR: Soumya Bhattacharya

GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE ANDTECHNOLOGY

GNIPST Photo Gallery

For your comments/contributionORFor Back-Issues,

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MESSAGE FROM GNIPSTGNIPST BULLETIN is the official publication of Guru Nanak

Institute of Pharmaceutical Science & Technology. All the

members of GNIPST are proud to publish the 26th

Volume of

GNIPST BULLETIN. Over the last two years this bulletin

updating readers with different scientific, cultural or sports

activities of this prestigious institute and promoting knowledge of

recent development in Pharmaceutical and Biological Sciences.

Students section is informing readers about some curious facts of

drug discovery, science, sports and other relevant fields. We look

forward to seeing your submission and welcome comments and

ideas you may have.

LETTER TO THE EDITOR.

NEWS UPDATE

International Day Against Drug Abuse and Illicit

Trafficking :26 June,2013

The International Day Against Drug Abuse and Illicit Trafficking on

26th june . this day is observed with United Nation coordiation to

strengthen action and cooperation to achieve the goal of an

international society free of drug abuse. The theme of this year is

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"Make health your 'new high' in life, not drugs" aims to inform the

public and particularly young people, about the harmful effects of

new psychoactive substances (NPS) or legal high substances. Today,

there is an alarming new drug problem; demand has soared for

substances not under international control. veryone has a part to play

in protecting the youth of the world from dangerous substances.

UNODC leads the annual World Drug Campaign to drive home the

message that illicit drugs pose a danger to society, aims to mobilize

wide public support and seeks to inspire people to act against drugabuse. Read more

Gene mutation may have effect on benefit of

aspirin use for colorectal cancer(25th June, 2013)According to recent clinical trials, the association between aspirin use

and risk of colorectal cancer was affected by mutation of the gene

BRAF, with regular aspirin use associated with a lower risk of BRAF-

wild-type colorectal cancer but not with risk of BRAF-mutated

cancer. The findings suggest that BRAF-mutant colon tumor cells

may be less sensitive to the effect of aspirin.Read more

Novel therapy to treat Muscular Dystrophy (25th June,

2013)Researchers at Boston University College of Health & Rehabilitation

Sciences: Sargent College have identified a combinatorial therapeutic

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approach that has proven effective in treating muscular dystrophy in a

mouse model.Read more

Antibiotic shows analgesic action following surgery(25th June, 2013)

Researchers at university Sapienza in Rome analyzed that a single

dose of the antibiotic Ceftriaxone given for antimicrobial prophylaxis

prior to surgery enhanced patient pain thresholds after the procedure.

Read more

Computerized brain fitness program improves the

memory of older adults(25th June, 2013)

Researchers have found that older adults who regularly used a brain-

fitness program called Dakim Brain Fitness on a computer

demonstrated significantly improved memory and language skills.

Read more

Nano goldfor vaccine development (25th June, 2013)US scientists have developed a novel vaccination method that uses

tiny gold particles to mimic a virus and carry specific proteins to the

body's specialist immune cells. The technique differs from the

traditional approach of using dead or inactive viruses as a vaccine and

was demonstrated in the lab using a specific protein that sits on the

surface of the respiratory syncytial virus (RSV).Read more

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New Palm-Sized Microarray Technique Grows

1,200 Individual Cultures of Microbes(25th June, 2013)Scientists at the University of Texas at San Antonio and the U.S.Army Institute of Surgical Research at Fort Sam Houston have

developed a microarray platform for culturing fungal biofilms, and

validated one potential application of the technology to identify new

drugs effective against Candida albicans biofilms.Read more

Zebra fish Study Paves the Way for NewTreatments for Genetic Disorder(26th June, 2013)

A research project conducted at the Sheffield Institute for

Translational Neuroscience (SITraN) and the MRC Centre for

Developmental and Biomedical Genetics (CDBG) by Dr Andrew

Grierson and his team has revealed that zebrafish could hold the key

to finding new therapeutic approaches to treat Charcot Marie Tooth

disease (CMT), a genetic disorderRead more

Simple Two-Drug Combination Proves Effective in

Reducing Risk of Stroke (26th June, 2013)

Results of a Phase III clinical trial showed that a simple drug regimen

of two anti-clotting drugs - clopidogrel and aspirin lowered the risk

of stroke by almost one-third, compared to the standard therapy of

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aspirin alone, when given to patients who had minor or transient

stroke symptoms to prevent subsequent attacks.Read more

HEALTH AWARENESS

Drug Abuse-A Psychosocial Disorder

Substance abuse or Drug abuse is a complex and multifactorial

disorder involving individual, cultural, biological, social and

environmental factors. Substance abuse refers to the harmful or

hazardous use of psychoactive substances, including alcohol and

illicit drugs. Psychoactive substance use can lead to dependence

syndrome which includes behavioural, cognitive, and physiological

phenomena that develop after repeated substance use and that

typically include a strong desire to take the drug, difficulties in

controlling its use, persisting in its use despite harmful consequences,

a higher priority given to drug use than to other activities andobligations, increased tolerance, and sometimes a physical

withdrawal state.

The World Drug report (UNODC 2009) estimates the

total number of people using illicit drugs at upwards of 250 million

peopleequivalent to about 4 per cent of the global population aged

15 to 64. Of that number, as many as 38 million people are drug

dependent, but only about 4.9 million of them receive evidence-based

drug dependence treatment and care.

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Glues

Paint thinner

Gasoline

Laughing gas

Aerosol sprays

Cannabinoids:

These drugs result in feelings of euphoria, cause confusion and

memory problems, anxiety, a higher heart rate, as well as staggering

and poor reaction time.

Types of drugs include:

Hashish

Marijuana

Depressants:

Depressants slow down activity in the central nervous system of your

body. These drugs are also called downers because they slow the

body down and seem to give feelings of relaxation. Depressants are

available as prescription drugs to relieve stress and anger, although

drowsiness is often a side effect. The relaxation felt from these drugs

is not a healthy feeling for the body to experience, to stop abuse of

this drug, drug treatment is suggested.

Types of drugs:

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Barbiturates

Benzodiazepines

Flunitrazepam

GHB (Gamma-hydroxybutyrate)

Methaqualone

Alcohol

Tranquillisers

Hallucinogens

When taking hallucinogens, switching emotions is frequent. These

drugs change the mind and cause the appearance of things that arenot really there. Hallucinogens affect the bodys self-control, such as

speech and movement, and often bring about hostility. Other negative

side effects of these drugs include heart failure, increased heart rate,

higher blood pressure and changes in the bodys hormones.


LSD (lysergic acid diethylamide)

Mescaline

Psilocybin

Cannabis

Magic Mushrooms

Prescription Drugs

Prescription drugs can be very helpful drugs when used properly and

when under the guidance of a qualified physician. These drugs can be

used as aids in surgery, to treat medical conditions and while

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controlling various symptoms. Misuse and abuse of prescription

drugs however can be very dangerous.


Opiods: Codeine, Oxycodone, Morphine

Central nervous system depressants: barbiturates, benzodiazepines

Stimulants: dextroamphetamine, methylphenidate

Common signs and symptoms of substance abuse:

Physical Symptoms: Glazed eye, Drowsiness, Runny nose,

Coughing, Needle marks, Weight loss, Malnutrition, Tremor,

Hallucination etc.

Emotional and social signs :

Moodiness, excitement, anger, hostility, depression

Constant lying and stealing

Refusing to admit to the harmful effects of drugs

Avoiding old friends or people who could confront them

about behavior changes

Being secretive about phone calls

Having friends they do not want you to meet or talk about

Being evasive about their whereabouts

Loss of motivation

No interest in everyday life

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Playing truant from school

Treatment strategies for substance abuse:

Drug dependence is as much a disorder of the brain as any other

neurological or psychiatric illness. One of the main barriers to

treatment and care is the stigma and discrimination associated with

this treatable health disorder. The major two approaches for the

treatment of substance abuse are

Psychosocial therapy: behavioral therapy, motivational therapy,

cognitive therapy, family therapy, social engagement

Pharmacotherapy: use of opioid agonist or use of some antagonist

(disulfiram for alcohol)

Impact of substance abuse on society and health:

The negative consequences of drug abuse affect not only individualswho abuse drugs but also their families and friends, societies, and

government resources.

The most obvious effects of drug abuse which are manifested in the

individuals who abuse drugs include ill health, sickness and,

ultimately, death.

Injecting drug abuser is more prone to needle borne infection like

hepatitis and HIV AIDS.

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Children of individuals who abuse drugs often are abused or

neglected as a result of the individuals' preoccupation with drugs.

Children whose parents and other family members abuse drugs oftenare physically or emotionally abused and often lack proper

immunizations, medical care, dental care, and necessities such as food,

water, and shelter.

The risk to children is even greater when their parents or guardians

manufacture illicit drugs such as methamphetamine.

Methamphetamine abusers often produce the drug in their own

homes and apartments, using hazardous chemicals such as hydriodic

acid, iodine, and anhydrous ammonia. Children who inhabit such

homes often inhale dangerous chemical fumes and gases or ingest

toxic chemicals or illicit drugs.

Alcohol use contributes to a wide range of diseases, health conditions

and high-risk behaviours, from mental disorders and road traffic

injuries, to liver diseases and unsafe sexual behaviour.

The economic impact of drug abuse on businesses whose employees

abuse drugs can be significant. While many drug abusers are unable

to attain or hold full-time employment, those who do work put others

at risk, particularly when employed in positions where even a minor

degree of impairment could be catastrophic; airline pilots, air traffic

controllers, train operators, and bus drivers are just a few examples.

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Drug or substance abuse is a social cancer. It is essential to stop

the further proliferation of this evil disorder. Only a pro-life attitude

of young generations can break this age old psychosocial dogma.

Source:

World Health Organization

UNODC

Narcotic Control Bureau, India

DISEASE OUTBREAK NEWS

Middle East respiratory syndrome corona virus

(MERS-CoV)(26thJune, 2013)

The Ministry of Health (MoH) in Saudi Arabia has announced seven

additional laboratory-confirmed cases and a death in a previously

confirmed case of Middle East respiratory syndrome coronavirus

(MERS-CoV).Read more

FORTHCOMING EVENTS

A Teachers Development Programme for SchoolTechers will be organized by GNIPST on 29th June, 2013

at college auditorium. The theme of the programme is

Recent Trends of Life Sciences in Higher Education

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Two short-term (2 weeks each) AICTE-sponsored refresher

courses on: Innovation and excellence in Pharmaceutical Sciences for

teaching staffs of the Indian Universities and colleges in QIP Nodal

Cell (Pharmacy), Department of Pharmaceutical Technology,

Jadavpur University, Kolkata-700 032 from 2nd July to 29th

July,2013.Read more

AICTE Sponsored Quality Improvement Programme on

Production to Prescription - Opportunities for Innovation on

MCOPS, Manipal University from 1-13th July, 2013.Read more

DRUGS UPDATES

FDA approves Vibativ for hospitalized patients with

bacterial pneumonia (21st June)The U.S. Food and Drug Administration today expanded the

approved use of the antibiotic Vibativ (telavancin) to treat patients

with hospital-acquired and ventilator-associated bacterial pneumonia(HABP/VABP) caused by Staphylococcus aureus. Vibativ should be

used for the treatment of HABP/VABP only when alternative

treatments are not suitable.Read more

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FDA approves Xgeva to treat giant cell tumor of

the bone (13th June, 2013)

The U.S. Food and Drug Administration today expanded theapproved use of Xgeva (denosumab) to treat adults and some

adolescents with giant cell tumor of the bone (GCTB), a rare and

usually non-cancerous tumor.Read more

CAMPUS NEWS

The following B.Pharm. final year students have qualified, GPAT-

2013. We congratulate them all.

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STUDENTS SECTION

WHO CAN ANSWER FIRST???

Which drug was first synthesized by C.R.A.Wright in 1984 ?

Which drug was first isolated by R. Mechoulamand Y .Gaoni?

Answer of Previous Issue Question:A)Albendazole B)Ancylostoma

Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for Students Section

& answers of this Section [email protected] NOTE

I am proud to publish the 3rd

issue of 26th

Volume of GNIPST

BULLETIN. GNIPST BULLETIN now connected globally through

facebook account GNIPST bulletin

I want to convey my thanks to all the GNIPST members and the

readers for their valuable comments, encouragement& supports.

I am thankful to Dr. Abhijit Sengupta, Director of GNIPST and

Prof. Dipankar Chakraborty, Registrar of GNIPST for their

valuable advice and encouragement. Special thanks to Dr. Prerona

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Saha andMr. Debabrata Ghosh Dastidar for their kind co-operation

and technical supports.

An important part of the improvement of the bulletin is the

contribution of the readers. You are invited to send in your write ups,

notes, critiques or any kind of contribution for the forthcoming special

and regular issue.

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ARCHIVE

The general body meeting of APTI, Bengal Branch has been conducted

at GNIPST on 15

th

June, 2012. The program started with a nicepresentation by Dr. Pulok Kr. Mukherjee, School of Natural Products,

JU on the skill to write a good manuscript for publication in impact

journals. It was followed by nearly two hour long discussion among

more than thirty participants on different aspects of pharmacy

education. Five nonmember participants applied for membership on

that very day.

GNIPST is now approved by AICTE and affiliated to WBUT for

conducting the two years post graduate course (M.Pharm) in

PHARMACOLOGY. The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to 120.

2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals),

Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and Dosimetry

(SWC-2013) : On the Way to Personalized Medicine

Dates 28 Feb 2013 02 Mar 2013

Location: Chandigarh, India.Details. AICTE has sanctioned a release of grant under Research Promotion

Scheme (RPS) during the financial year 2012-13to GNIPST as per the

details below:

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a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical

Science & Technology.

b. Principal Investigator: Dr. Lopamudra Dutta.

c. Grant-in-aid sanctioned :Rs. 16,25000/- only

d. Approved duration: 3 years

e. Title of the project: Screening and identification of potential

medicinal plant of Purulia& Bankura districts of West Bengal with

respect to diseases such as diabetes, rheumatism, Jaundice,

hypertension and developing biotechnological tools for enhancing

bioactive molecules in these plants.