gnipst bulletin 28.1

7/27/2019 Gnipst Bulletin 28.1

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9th

August, 2013 Volume No.: 28 Issue No.: 01

Contents• Message from GNIPS

•

Letter to the Editor • News Update

• Health awareness

• Disease Outbreak Ne

• Forth Coming Events

• Drugs Update

• Campus News

• Student’s Section

• Editor’s Note

• Archive

•

Vision

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O

PHARMACEUTICAL AND BIOLOGICAL SCIENCE

EDITOR:Soumya Bhattacharya GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND

TECHNOLOGY

GNIPST Photo Gallery

For your comments/contributionOR

For Back-Issues,

mailto:[email protected]

Admission in Biotechnology (M.Sc) and Genetics (M.Sc) is going on

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https://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7



09-08-2013

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MESSAGE FROM GNIPST GNIPST BULLETIN is the official publication of Guru Nanak

Institute of Pharmaceutical Science & Technology. All the members

of GNIPST are proud to publish the 28th Volume of “GNIPST

BULLETIN”. Over the last two years this bulletin updating readers

with different scientific, cultural or sports activities of this prestigious

institute and promoting knowledge of recent development in

Pharmaceutical and Biological Sciences. Student’s section is

informing readers about some curious facts of drug discovery, science,

sports and other relevant fields. We look forward to seeing your

submission and welcome comments and ideas you may have.

LETTER TO THE EDITOR.

NEWS UPDATE

World Hepatitis day,2013 (28th July, 2013)

The ‘World Hepatitis Day’ was observed on 28th July globally. Every

year on 28 July, WHO and partners mark World Hepatitis Day to

increase the awareness and understanding of viral hepatitis and the

diseases that it causes. The theme of this year is "This is hepatitis.

Know it. Confront it." Hepatitis viruses A, B, C, D and E can cause

acute and chronic infection and inflammation of the liver that can lead

to cirrhosis and liver cancer. These viruses constitute a major global

health risk with around 240 million people being chronically infected with hepatitis B and around 150 million people chronically infected

with hepatitis C. World Hepatitis Day provides an opportunity to

focus on specific actions, such as:

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• strengthening prevention, screening and control of viral hepatitis

and its related diseases;

• increasing hepatitis B vaccine coverage and integration of the

vaccine into national immunization programmes;

• coordinating a global response to viral hepatitis. Read more

World Breastfeeding Week (1st August, 2013)

World Breastfeeding Week is celebrated every year from 1 to 7 August

in more than 170 countries to encourage breastfeeding and improve

the health of babies around the world. It commemorates the Innocenti

Declaration made by WHO and UNICEF policy-makers in August1990 to protect, promote and support breastfeeding.

Breastfeeding is the best way to provide newborns with the nutrients

they need. WHO recommends exclusive breastfeeding until a baby is

six months old and continued breastfeeding with the addition of

nutritious complementary foods for up to two years or beyond. Read

more

Breastfed children are less likely to develop adhd

later in life (22nd July, 2013) Researchers from Tel Aviv University have shown that breastfeeding

may also help protect against Attention Deficit/Hyperactivity

Disorder (ADHD), the most commonly diagnosed neurobehavioral

disorder in children and adolescents. Read more

Linked between Psoriasis and other medical

condition established (7th August, 2013)

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http://www.who.int/campaigns/hepatitis-day/2013/en/index.html



http://www.who.int/mediacentre/events/meetings/2013/world_breastfeeding_week/en/index.html




http://www.sciencedaily.com/releases/2013/07/130722152739.htm









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Recent study revealed that that people with psoriasis had higher

rates of chronic lung disease, diabetes, mild liver disease, heart

attack, peptic ulcer, peripheral vascular disease, kidney disease

and rheumatologic disease. Read more

High blood sugar levels tied to small increases in

dementia risk (7th August , 2013)

Elevated blood sugar levels, even among people who don't have

diabetes, are associated with an increased risk for dementia, a new

study shows. The effect was very subtle, however, suggesting that

higher blood sugar levels may be more of a nudge toward memory

loss than a shove. Read more

Obese kids more likely to have asthma, with worse

symptoms (7th August, 2013)

Overweight and obese kids are more likely to struggle with

asthma than kids of normal weight, according to a new review of more than 623,000 children.Researchers found that childrencarrying extra weight are between 1.16 to 1.37 times more likely todevelop asthma than normal-weight kids, with the risk growing as

their body-mass index Read more

Gold 'nanoprobes' hold the key to treating

killer diseases (7th August, 2013) Researchers at the University of Southampton, in collaborationwith colleagues at the University of Cambridge, have developed a

technique to help treat fatal diseases more effectively. Dr Sumeet

Mahajan and his group at the Institute for Life Sciences at

Southampton are using gold nanoprobes to identify different types

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http://www.drugs.com/news/psoriasis-other-medical-conditions-may-linked-study-says-46548.html



http://www.drugs.com/news/blood-sugar-levels-tied-small-increases-dementia-risk-46552.html



http://www.sciencedaily.com/releases/2013/08/130801233032.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29


















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of cells, so that they can use the right ones in stem cell therapies. Read more

Genes that drive brain cancer revealed (7th August,

2013) A team of researchers at the Herbert Irving Comprehensive Cancer

Center at Columbia University Medical Center has identified 18

new genes responsible for driving glioblastoma multiforme, the

most common and most aggressive form of brain cancer in adults.

Read more

HEALTH AWARENESS

Salmonella-WHO Key Facts

Key facts

• Salmonellosis, is one of the most common and widely distributed foodborne diseases, with tens of millions of human cases occurringworldwide every year.

• Most cases of salmonellosis are mild, however, sometimes peopledie from salmonellosis. The severity of the disease may depend onhost factors and the strain of Salmonella.

• Since the beginning of the 1990s, Salmonella strains which areresistant to a range of antimicrobials have emerged and are now aserious public health concern.

• Basic food hygiene practices, such as "cook thoroughly", isrecommended as a preventive measure against salmonellosis.Overview

Salmonellosis is one of the most common and widely distributed foodborne diseases and is caused by the bacteria Salmonella. It isestimated that tens of millions of human cases occur worldwide

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every year and the disease results in more than hundred thousand deaths. For Salmonella species, over 2 500 different strains (called "serotypes" or "serovars") have been identified to date. Salmonella isa ubiquitous and hardy bacteria that can survive several weeks in a

dry environment and several months in water.While all serotypes can cause disease in humans, a few are hostspecific and can reside in only one or a few animal species, forexample, Salmonella Dublin in cattle; and Salmonella Choleraesuis inpigs. When these particular serotypes cause disease in humans, itis often invasive and can be life-threatening. Most serotypes,however, are present in a wide range of hosts. Typically, suchstrains cause gastroenteritis, which is often uncomplicated and

does not need treatment, but can be severe in the young, theelderly and patients with weakened immunity. This groupfeatures Salmonella Enteritidis and Salmonella Typhimurium, thetwo most important serotypes of salmonellosis transmitted fromanimals to humans in most parts of the world.The disease

Salmonellosis is a disease caused by the bacteria Salmonella. It isusually characterized by acute onset of fever, abdominal pain,

diarrhoea, nausea and sometimes vomiting.The onset of disease symptoms occurs 6 - 72 hours (usually 12-36hours) after ingestion of Salmonella, and illness lasts 2-7 days.Symptoms of salmonellosis are relatively mild and patients willmake a recovery without specific treatment in most cases.However, in some cases, particularly in the very young and in theelderly patients, the associated dehydration can become severe and life-threatening.

Although large Salmonella outbreaks usually attract mediaattention, 60 to 80% of all salmonellosis cases are not recognized as part of a known outbreak and are classified as sporadic cases, orare not diagnosed as such at all.Sources and transmission

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• Salmonella bacteria are widely distributed in domestic and wild animals. They are prevalent in food animals such as poultry, pigs,cattle; and in pets, including cats and dogs, birds and reptiles suchas turtles.

• Salmonella can pass through the entire food chain from animal feed,primary production, and all the way to households or food-serviceestablishments and institutions.

• Salmonellosis in humans is generally contracted through theconsumption of contaminated food of animal origin (mainly eggs,meat, poultry and milk), although other foods, including greenvegetables contaminated by manure, have been implicated in itstransmission.

• Person-to-person transmission through the faecal-oral route canalso occur.• Human cases also occur where individuals have contact with

infected animals, including pets. These infected animals often donot show signs of disease.Treatment

Treatment in severe cases is symptomatic, electrolyte replacement(to provide electrolytes, such as sodium, potassium and chloride

ions, lost through vomiting and diarrhoea) and rehydration.Routine antimicrobial therapy is not recommended for mild ormoderate cases in healthy individuals. This is becauseantimicrobials may not completely eliminate the bacteria and mayselect for resistant strains, which subsequently can lead to thedrug becoming ineffective. However, health risk groups such asinfants, the elderly and immunocompromised patients may need toreceive antimicrobial therapy. Antimicrobials are alsoadministered if the infection spreads from the intestine to otherbody parts. Because of the global increase of antimicrobialresistance, treatment guidelines should be reviewed on a regularbasis taking into account the resistance pattern of the bacteria.Prevention methods

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Prevention requires control measures at all stages of the food chain, from agricultural production, to processing, manufacturingand preparation of foods in both commercial establishments and athome.

Preventive measures for Salmonella in the home are similar to thoseused against other foodborne bacterial diseases (see"Recommendations for food handlers" below).Some animals can also pass the bacteria directly to people. Thecontact between infants/young children and pet animals (cats,dogs, turtles etc.) needs careful supervision.National/regional surveillance systems are important means todetect and respond to salmonellosis and other enteric infections in

early stages, and thus to prevent them from further spreading.Recommendations for the public and travellers

• Ensure food is properly cooked and still hot when served.• Avoid raw milk and products made from raw milk. Drink only

pasteurized or boiled milk.• Avoid ice unless it is made from safe water.• When the safety of drinking water is questionable, boil it or if this

is not possible, disinfect it with a reliable, slow-release

disinfectant agent (usually available at pharmacies).• Wash hands thoroughly and frequently using soap, in particular

after contact with pets or farm animals, or after having been to thetoilet.

• Wash fruits and vegetables carefully, particularly if they are eatenraw. If possible, vegetables and fruits should be peeled.

• When travelling, refer to WHO's brochure A guide on safe food for travellers.Recommendations for food handlers

• Both professional and domestic food handlers should be vigilantwhile preparing food and should observe hygienic rules of food preparation.

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• Professional food handlers who suffer from fever, diarrhoea,vomiting or visible infected skin lesions should report to theiremployer immediately.

• The WHO Five Keys to Safer Food serve as the basis for

educational programmes to train food handlers and educateconsumers. They are especially important in preventing food poisoning. The Five Keys are:

1. Keep clean.2. Separate raw and cooked.3. Cook thoroughly.4. Keep food at safe temperatures.5. Use safe water and raw materials.

Recommendations for producers of fruits and vegetablesThe WHO Five Keys to Growing Safer Fruits and Vegetables3 isan educational manual for rural workers, including small farmerswho grow fresh fruits and vegetables for themselves, their familiesand for sale in local market. It provides them with key practices toprevent microbial contamination of fresh produces duringplanting, growing, harvesting and storing.The Five keys practices are:

•

Practice good personal hygiene.• Protect fields from animal faecal contamination.• Use treated faecal waste.• Evaluate and manage risks from irrigation water.• Keep harvest and storage equipment clean and dry.

WHO response

• WHO promotes the strengthening of food safety systems,promoting good manufacturing practices and educating retailers

and consumers about appropriate food handling and avoidingcontamination. Education of consumers and training of food handlers in safe food handling is one of the most critical means toprevent foodborne illnesses including salmonellosis.

• WHO strengthens and enhances the capacities of national and regional laboratories in the surveillance of Salmonella, the othermajor foodborne pathogens and antimicrobial resistance

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in Salmonella and Campylobacter from humans, food and animalsthrough the network called Global Foodborne Infections Network(GFN) .

• WHO’s main tool to assist Member States in surveillance,

coordination and response to outbreaks is the use of theInternational Network of Food Safety Authorities (INFOSAN) .which links national authorities in Member States in charge of managing food safety events. This network is managed jointly byFAO and WHO.

DISEASE OUTBREAK NEWS

Middle East Respiratory Syndrome coronavirus

(MERS-CoV) (1st August, 2013) WHO has been informed of an additional three laboratory-confirmed

cases of Middle East respiratory syndrome coronavirus (MERS-CoV)

infection in Saudi Arabia. Read more

FORTHCOMING EVENTS

The 2nd Pharm. Tech IAPST International Conference on "New insights into

diseases and recent therapeutic approaches" from 17th to 19th January 2014 in

Kolkata, India. Read more

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http://www.who.int/csr/don/2013_08_01/en/index.html



http://www.iapst.com/







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DRUGS UPDATES

FDA Approves Injectafer for Iron Deficiency

Anemia

Injectafer (ferric carboxymaltose injection) has received U.S. Food

and Drug Administration (FDA) approval. Injectafer is a

parenteral iron replacement product used for the treatment of iron

deficiency anemia (IDA) in adult patients who have intolerance to

oral iron or have had an unsatisfactory response to oral iron.

Injectafer is also indicated for iron deficiency anemia in adult

patients with non-dialysis dependent chronic kidney disease(NND-CKD). Read more

FDA permits marketing of first U.S. test

labeled for simultaneous detection of

tuberculosis bacteria and resistance to the

antibiotic rifampin (25th July) The U.S. Food and Drug Administration today allowed marketingof the Xpert MTB/RIF Assay, the first FDA-reviewed test that can

simultaneously detect bacteria that cause tuberculosis (TB) and

determine if the bacteria contain genetic markers that makes them

resistant to rifampin, an important antibiotic for the treatment of

TB. Read more

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http://www.drugs.com/injectafer.html


http://www.drugs.com/newdrugs/fda-approves-injectafer-iron-deficiency-anemia-3858.html



http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm362602.htm








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discussion platform for school teachers and professional of the

emerging and newer branches of Life Science.

The following B.Pharm. final year students have qualified, GPAT-

2013. We congratulate them all.

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STUDENTS’ SECTION

WHO CAN ANSWER FIRST????

Which pathophysiological term is derived from

Greek word ‘falling from’?

Which pathophysiological term is derived from Greek word ‘act of killing’?

Answer of Previous Issue’s Questions: A) B.S. Blumberg B)Liver transplantation

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Send your thoughts/ Quiz/Puzzles/games/write-

ups or any other contributions for Students’

Section& answers of this Section [email protected]

EDITOR’S NOTE

I am proud to publish the 1st

issue of 28th

Volume of GNIPST

BULLETIN.GNIPST BULLETIN now connected globally through

facebook account ‘GNIPST bulletin’

I want to convey my thanks to all the GNIPST members and the

readers for their valuable comments, encouragement and supports.

I am thankful to Dr. Abhijit Sengupta, Director of GNIPST for his

valuable advice and encouragement. Special thanks to Dr. Prerona

Saha and Mr. Debabrata Ghosh Dastidar for their kind co-operation

and technical supports.

An important part of the improvement of the bulletin is the

contribution of the readers. You are invited to send in your write ups,

notes, critiques or any kind of contribution for the forthcoming special

and regular issue.

ARCHIVE

The general body meeting of APTI, Bengal Branch has been conducted

at GNIPST on 15th June, 2012. The program started with a nice

presentation by Dr. Pulok Kr. Mukherjee, School of Natural Products,

JU on the skill to write a good manuscript for publication in impact

journals. It was followed by nearly two hour long discussion among

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gnipst bulletin 28.1

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